Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	79634
Gene name	Secernin 3
Gene symbol	SCRN3
Synonyms (NCBI Gene)	SES3
Chromosome	2
Chromosome location	2q31.1

149

Show/Hide all (149)

miRTarBase ID	miRNA	Experiments	Reference
MIRT024716	hsa-miR-215-5p	Microarray	19074876
MIRT026160	hsa-miR-192-5p	Microarray	19074876
MIRT732863	hsa-let-7b-5p	MicroarrayqRT-PCR	33946378
MIRT1330835	hsa-miR-1293	CLIP-seq
MIRT1330836	hsa-miR-186	CLIP-seq
MIRT1330837	hsa-miR-299-3p	CLIP-seq
MIRT1330838	hsa-miR-30a	CLIP-seq
MIRT1330839	hsa-miR-30b	CLIP-seq
MIRT1330840	hsa-miR-30c	CLIP-seq
MIRT1330841	hsa-miR-30d	CLIP-seq
MIRT1330842	hsa-miR-30e	CLIP-seq
MIRT1330843	hsa-miR-3133	CLIP-seq
MIRT1330844	hsa-miR-3607-5p	CLIP-seq
MIRT1330845	hsa-miR-3912	CLIP-seq
MIRT1330846	hsa-miR-3942-3p	CLIP-seq
MIRT1330847	hsa-miR-4428	CLIP-seq
MIRT1330848	hsa-miR-4434	CLIP-seq
MIRT1330849	hsa-miR-4455	CLIP-seq
MIRT1330850	hsa-miR-4483	CLIP-seq
MIRT1330851	hsa-miR-4506	CLIP-seq
MIRT1330852	hsa-miR-4516	CLIP-seq
MIRT1330853	hsa-miR-4712-3p	CLIP-seq
MIRT1330854	hsa-miR-4773	CLIP-seq
MIRT1330855	hsa-miR-545	CLIP-seq
MIRT1330856	hsa-miR-548a-3p	CLIP-seq
MIRT1330857	hsa-miR-548e	CLIP-seq
MIRT1330858	hsa-miR-548f	CLIP-seq
MIRT1330859	hsa-miR-570	CLIP-seq
MIRT1330860	hsa-miR-601	CLIP-seq
MIRT1330861	hsa-miR-609	CLIP-seq
MIRT1330862	hsa-miR-885-3p	CLIP-seq
MIRT1330863	hsa-miR-1277	CLIP-seq
MIRT1330835	hsa-miR-1293	CLIP-seq
MIRT1330836	hsa-miR-186	CLIP-seq
MIRT1330864	hsa-miR-298	CLIP-seq
MIRT1330837	hsa-miR-299-3p	CLIP-seq
MIRT1330865	hsa-miR-3129-3p	CLIP-seq
MIRT1330843	hsa-miR-3133	CLIP-seq
MIRT1330866	hsa-miR-3591-3p	CLIP-seq
MIRT1330844	hsa-miR-3607-5p	CLIP-seq
MIRT1330867	hsa-miR-3622a-3p	CLIP-seq
MIRT1330868	hsa-miR-3622b-3p	CLIP-seq
MIRT1330869	hsa-miR-3678-3p	CLIP-seq
MIRT1330870	hsa-miR-3713	CLIP-seq
MIRT1330845	hsa-miR-3912	CLIP-seq
MIRT1330871	hsa-miR-410	CLIP-seq
MIRT1330872	hsa-miR-4291	CLIP-seq
MIRT1330849	hsa-miR-4455	CLIP-seq
MIRT1330850	hsa-miR-4483	CLIP-seq
MIRT1330851	hsa-miR-4506	CLIP-seq
MIRT1330873	hsa-miR-4733-5p	CLIP-seq
MIRT1330874	hsa-miR-4744	CLIP-seq
MIRT1330854	hsa-miR-4773	CLIP-seq
MIRT1330875	hsa-miR-499-3p	CLIP-seq
MIRT1330876	hsa-miR-499a-3p	CLIP-seq
MIRT1330877	hsa-miR-519a	CLIP-seq
MIRT1330878	hsa-miR-519b-3p	CLIP-seq
MIRT1330879	hsa-miR-519c-3p	CLIP-seq
MIRT1330855	hsa-miR-545	CLIP-seq
MIRT1330856	hsa-miR-548a-3p	CLIP-seq
MIRT1330857	hsa-miR-548e	CLIP-seq
MIRT1330858	hsa-miR-548f	CLIP-seq
MIRT1330880	hsa-miR-548n	CLIP-seq
MIRT1330881	hsa-miR-548t	CLIP-seq
MIRT1330882	hsa-miR-586	CLIP-seq
MIRT1330861	hsa-miR-609	CLIP-seq
MIRT1330883	hsa-miR-633	CLIP-seq
MIRT1330884	hsa-miR-662	CLIP-seq
MIRT2097881	hsa-miR-3160-5p	CLIP-seq
MIRT2322355	hsa-miR-1200	CLIP-seq
MIRT2322356	hsa-miR-1276	CLIP-seq
MIRT1330863	hsa-miR-1277	CLIP-seq
MIRT2322357	hsa-miR-144	CLIP-seq
MIRT2322358	hsa-miR-1912	CLIP-seq
MIRT2322359	hsa-miR-1913	CLIP-seq
MIRT2322360	hsa-miR-324-3p	CLIP-seq
MIRT2322361	hsa-miR-3663-3p	CLIP-seq
MIRT1330846	hsa-miR-3942-3p	CLIP-seq
MIRT2322362	hsa-miR-409-3p	CLIP-seq
MIRT1330872	hsa-miR-4291	CLIP-seq
MIRT2322363	hsa-miR-4324	CLIP-seq
MIRT2322364	hsa-miR-4749-3p	CLIP-seq
MIRT2322365	hsa-miR-526b	CLIP-seq
MIRT2322366	hsa-miR-544b	CLIP-seq
MIRT1330855	hsa-miR-545	CLIP-seq
MIRT2322367	hsa-miR-578	CLIP-seq
MIRT1330883	hsa-miR-633	CLIP-seq
MIRT2618623	hsa-miR-1304	CLIP-seq
MIRT2322357	hsa-miR-144	CLIP-seq
MIRT2322358	hsa-miR-1912	CLIP-seq
MIRT1330838	hsa-miR-30a	CLIP-seq
MIRT1330839	hsa-miR-30b	CLIP-seq
MIRT1330840	hsa-miR-30c	CLIP-seq
MIRT1330841	hsa-miR-30d	CLIP-seq
MIRT1330842	hsa-miR-30e	CLIP-seq
MIRT2618624	hsa-miR-3146	CLIP-seq
MIRT2618625	hsa-miR-3662	CLIP-seq
MIRT2618626	hsa-miR-369-3p	CLIP-seq
MIRT2618627	hsa-miR-374a	CLIP-seq
MIRT2618628	hsa-miR-374b	CLIP-seq
MIRT1330846	hsa-miR-3942-3p	CLIP-seq
MIRT2618629	hsa-miR-4252	CLIP-seq
MIRT2618630	hsa-miR-4420	CLIP-seq
MIRT2618631	hsa-miR-4652-3p	CLIP-seq
MIRT2618632	hsa-miR-4698	CLIP-seq
MIRT1330853	hsa-miR-4712-3p	CLIP-seq
MIRT2618633	hsa-miR-4725-5p	CLIP-seq
MIRT2618634	hsa-miR-4765	CLIP-seq
MIRT2618635	hsa-miR-4777-3p	CLIP-seq
MIRT2618636	hsa-miR-504	CLIP-seq
MIRT2618637	hsa-miR-5096	CLIP-seq
MIRT2618638	hsa-miR-548c-3p	CLIP-seq
MIRT2618639	hsa-miR-577	CLIP-seq
MIRT2322367	hsa-miR-578	CLIP-seq
MIRT2618640	hsa-miR-605	CLIP-seq
MIRT2618641	hsa-miR-944	CLIP-seq
MIRT2690287	hsa-miR-106a	CLIP-seq
MIRT2690288	hsa-miR-106b	CLIP-seq
MIRT2690289	hsa-miR-1264	CLIP-seq
MIRT2322356	hsa-miR-1276	CLIP-seq
MIRT2690290	hsa-miR-17	CLIP-seq
MIRT2690291	hsa-miR-20a	CLIP-seq
MIRT2690292	hsa-miR-20b	CLIP-seq
MIRT1330838	hsa-miR-30a	CLIP-seq
MIRT1330839	hsa-miR-30b	CLIP-seq
MIRT1330840	hsa-miR-30c	CLIP-seq
MIRT1330841	hsa-miR-30d	CLIP-seq
MIRT1330842	hsa-miR-30e	CLIP-seq
MIRT2618624	hsa-miR-3146	CLIP-seq
MIRT2690293	hsa-miR-3691-3p	CLIP-seq
MIRT2618630	hsa-miR-4420	CLIP-seq
MIRT2690294	hsa-miR-4480	CLIP-seq
MIRT2618631	hsa-miR-4652-3p	CLIP-seq
MIRT2690295	hsa-miR-4662a-5p	CLIP-seq
MIRT2618633	hsa-miR-4725-5p	CLIP-seq
MIRT2618634	hsa-miR-4765	CLIP-seq
MIRT2618635	hsa-miR-4777-3p	CLIP-seq
MIRT2690296	hsa-miR-495	CLIP-seq
MIRT2618636	hsa-miR-504	CLIP-seq
MIRT2618637	hsa-miR-5096	CLIP-seq
MIRT1330877	hsa-miR-519a	CLIP-seq
MIRT1330878	hsa-miR-519b-3p	CLIP-seq
MIRT1330879	hsa-miR-519c-3p	CLIP-seq
MIRT2690297	hsa-miR-519d	CLIP-seq
MIRT2618638	hsa-miR-548c-3p	CLIP-seq
MIRT1330881	hsa-miR-548t	CLIP-seq
MIRT2618639	hsa-miR-577	CLIP-seq
MIRT2322367	hsa-miR-578	CLIP-seq
MIRT2690298	hsa-miR-93	CLIP-seq

Show/Hide all (5)

GO ID	Ontology	Definition	Evidence
GO:0006508	Process	Proteolysis	IEA
GO:0016805	Function	Dipeptidase activity	IEA
GO:0050965	Process	Detection of temperature stimulus involved in sensory perception of pain	IEA
GO:0050965	Process	Detection of temperature stimulus involved in sensory perception of pain	ISS
GO:0070004	Function	Cysteine-type exopeptidase activity	IEA

MIM	HGNC	e!Ensembl
614967	30382	ENSG00000144306

Q0VDG4

Protein name

Secernin-3

Protein function

Plays a role in thermal nociception.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03577	Peptidase_C69	77 → 271	Peptidase family C69	Family

Sequence

MEPFSCDTFVALPPATVDNRIIFGKNSDRLYDEVQEVVYFPAVVHDNLGERLKCTYIEID
QVPETYAVVLSRPAWLWGAEMGANEHGVCIGNEAVWGREEVCDEEALLGMDLVRLGLERA
DTAEKALNVIVDLLEKYGQGGNCTEGRMVFSYHNSFLIADRNEAWILETAGKYWAAEKVQ
EGVRNISNQLSITTKIAREHPDMRNYAKRKGWWDGKKEFDFAAAYSYLDTAKMMTSSGRY
CEGYKLLNKHKGNITFETMMEILRDKPSGINMEGEFLTTASMVSILPQDSSLPCIHFFTG
TPDPERSVFKPFIFVPHISQLLDTSSPTFELEDLVKKKSHFKPDRRHPLYQKHQQALEVV
NNNEEKAKIMLDNMRKLEKELFREMESILQNKHLDVEKIVNLFPQCTKDEIQIYQSNLSV
KVSS

Sequence length

424

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
METABOLIC SYNDROME	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCOLIOSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (1)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Alzheimer Disease	Alzheimer disease	Pubtator	37149819	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

SCRN3 (secernin 3)