Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	79570
Gene name	Sodium/potassium transporting ATPase interacting 1
Gene symbol	NKAIN1
Synonyms (NCBI Gene)	FAM77C
Chromosome	1
Chromosome location	1p35.2
Summary	NKAIN1 is a member of a family of mammalian proteins with similarity to Drosophila Nkain and interacts with the beta subunit of Na,K-ATPase (ATP1B1; MIM 182330) (Gorokhova et al., 2007 [PubMed 17606467]).[supplied by OMIM, Jun 2009]

Show/Hide all (95)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018420	hsa-miR-335-5p	Microarray	18185580
MIRT1185949	hsa-miR-1193	CLIP-seq
MIRT1185950	hsa-miR-1266	CLIP-seq
MIRT1185951	hsa-miR-128	CLIP-seq
MIRT1185952	hsa-miR-1289	CLIP-seq
MIRT1185953	hsa-miR-1343	CLIP-seq
MIRT1185954	hsa-miR-141	CLIP-seq
MIRT1185955	hsa-miR-185	CLIP-seq
MIRT1185956	hsa-miR-200a	CLIP-seq
MIRT1185957	hsa-miR-219-1-3p	CLIP-seq
MIRT1185958	hsa-miR-2278	CLIP-seq
MIRT1185959	hsa-miR-2355-5p	CLIP-seq
MIRT1185960	hsa-miR-27a	CLIP-seq
MIRT1185961	hsa-miR-27b	CLIP-seq
MIRT1185962	hsa-miR-296-5p	CLIP-seq
MIRT1185963	hsa-miR-3074-5p	CLIP-seq
MIRT1185964	hsa-miR-30a	CLIP-seq
MIRT1185965	hsa-miR-30b	CLIP-seq
MIRT1185966	hsa-miR-30c	CLIP-seq
MIRT1185967	hsa-miR-30d	CLIP-seq
MIRT1185968	hsa-miR-30e	CLIP-seq
MIRT1185969	hsa-miR-3122	CLIP-seq
MIRT1185970	hsa-miR-3124-3p	CLIP-seq
MIRT1185971	hsa-miR-3135b	CLIP-seq
MIRT1185972	hsa-miR-3150b-3p	CLIP-seq
MIRT1185973	hsa-miR-3166	CLIP-seq
MIRT1185974	hsa-miR-3170	CLIP-seq
MIRT1185975	hsa-miR-3198	CLIP-seq
MIRT1185976	hsa-miR-342-5p	CLIP-seq
MIRT1185977	hsa-miR-3607-3p	CLIP-seq
MIRT1185978	hsa-miR-3652	CLIP-seq
MIRT1185979	hsa-miR-3679-3p	CLIP-seq
MIRT1185980	hsa-miR-3686	CLIP-seq
MIRT1185981	hsa-miR-3689d	CLIP-seq
MIRT1185982	hsa-miR-3690	CLIP-seq
MIRT1185983	hsa-miR-3913-5p	CLIP-seq
MIRT1185984	hsa-miR-3919	CLIP-seq
MIRT1185985	hsa-miR-4254	CLIP-seq
MIRT1185986	hsa-miR-4259	CLIP-seq
MIRT1185987	hsa-miR-4260	CLIP-seq
MIRT1185988	hsa-miR-4270	CLIP-seq
MIRT1185989	hsa-miR-4286	CLIP-seq
MIRT1185990	hsa-miR-4294	CLIP-seq
MIRT1185991	hsa-miR-4299	CLIP-seq
MIRT1185992	hsa-miR-4306	CLIP-seq
MIRT1185993	hsa-miR-4309	CLIP-seq
MIRT1185994	hsa-miR-4424	CLIP-seq
MIRT1185995	hsa-miR-4430	CLIP-seq
MIRT1185996	hsa-miR-4434	CLIP-seq
MIRT1185997	hsa-miR-4441	CLIP-seq
MIRT1185998	hsa-miR-4450	CLIP-seq
MIRT1185999	hsa-miR-4468	CLIP-seq
MIRT1186000	hsa-miR-4487	CLIP-seq
MIRT1186001	hsa-miR-450b-3p	CLIP-seq
MIRT1186002	hsa-miR-4516	CLIP-seq
MIRT1186003	hsa-miR-4518	CLIP-seq
MIRT1186004	hsa-miR-4531	CLIP-seq
MIRT1186005	hsa-miR-4644	CLIP-seq
MIRT1186006	hsa-miR-4651	CLIP-seq
MIRT1186007	hsa-miR-4664-5p	CLIP-seq
MIRT1186008	hsa-miR-4727-3p	CLIP-seq
MIRT1186009	hsa-miR-4752	CLIP-seq
MIRT1186010	hsa-miR-4756-3p	CLIP-seq
MIRT1186011	hsa-miR-4758-3p	CLIP-seq
MIRT1186012	hsa-miR-4784	CLIP-seq
MIRT1186013	hsa-miR-485-5p	CLIP-seq
MIRT1186014	hsa-miR-488	CLIP-seq
MIRT1186015	hsa-miR-513a-5p	CLIP-seq
MIRT1186016	hsa-miR-541	CLIP-seq
MIRT1186017	hsa-miR-608	CLIP-seq
MIRT1186018	hsa-miR-629	CLIP-seq
MIRT1186019	hsa-miR-654-5p	CLIP-seq
MIRT1186020	hsa-miR-765	CLIP-seq
MIRT1186021	hsa-miR-769-3p	CLIP-seq
MIRT1185951	hsa-miR-128	CLIP-seq
MIRT1185960	hsa-miR-27a	CLIP-seq
MIRT1185961	hsa-miR-27b	CLIP-seq
MIRT2053930	hsa-miR-4268	CLIP-seq
MIRT2053931	hsa-miR-4300	CLIP-seq
MIRT2053932	hsa-miR-4448	CLIP-seq
MIRT1186015	hsa-miR-513a-5p	CLIP-seq
MIRT2053933	hsa-miR-920	CLIP-seq
MIRT1185960	hsa-miR-27a	CLIP-seq
MIRT1185961	hsa-miR-27b	CLIP-seq
MIRT2391574	hsa-miR-3659	CLIP-seq
MIRT1185981	hsa-miR-3689d	CLIP-seq
MIRT2391575	hsa-miR-3929	CLIP-seq
MIRT2391576	hsa-miR-4280	CLIP-seq
MIRT2391577	hsa-miR-4419b	CLIP-seq
MIRT1185998	hsa-miR-4450	CLIP-seq
MIRT2391578	hsa-miR-4478	CLIP-seq
MIRT2391579	hsa-miR-4658	CLIP-seq
MIRT1186009	hsa-miR-4752	CLIP-seq
MIRT1186013	hsa-miR-485-5p	CLIP-seq
MIRT2391580	hsa-miR-574-5p	CLIP-seq

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GO ID	Ontology	Definition	Evidence
GO:0002028	Process	Regulation of sodium ion transport	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0016020	Component	Membrane	IEA
GO:0051117	Function	ATPase binding	IEA

MIM	HGNC	e!Ensembl
612871	25743	ENSG00000084628

Q4KMZ8

Protein name

Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 (Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 1) (Protein FAM77C)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF05640	NKAIN	1 → 206	Na,K-Atpase Interacting protein	Family

Sequence

MGKCSGRCTLVAFCCLQLVAALERQIFDFLGYQWAPILANFLHIMAVILGIFGTVQYRSR
YLILYAAWLVLWVGWNAFIICFYLEVGQLSQDRDFIMTFNTSLHRSWWMENGPGCLVTPV
LNSRLALEDHHVISVTGCLLDYPYIEALSSALQIFLALFGFVFACYVSKVFLEEEDSFDF
IGGFDSYGYQAPQKTSHLQLQPLYTSG

Sequence length

207

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
COLOR VISION DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (1)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	34777331	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

NKAIN1 (sodium/potassium transporting ATPase interacting 1)