Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	79168
Gene name	Leukocyte immunoglobulin like receptor A6
Gene symbol	LILRA6
Synonyms (NCBI Gene)	CD85bILT-8ILT5ILT8LILRB3LILRB6
Chromosome	19
Chromosome location	19q13.42

258

Show/Hide all (258)

miRTarBase ID	miRNA	Experiments
MIRT1109258	hsa-miR-1255a	CLIP-seq
MIRT1109259	hsa-miR-1255b	CLIP-seq
MIRT1109260	hsa-miR-1261	CLIP-seq
MIRT1109261	hsa-miR-128	CLIP-seq
MIRT1109262	hsa-miR-130a	CLIP-seq
MIRT1109263	hsa-miR-130b	CLIP-seq
MIRT1109264	hsa-miR-138	CLIP-seq
MIRT1109265	hsa-miR-147	CLIP-seq
MIRT1109266	hsa-miR-148a	CLIP-seq
MIRT1109267	hsa-miR-148b	CLIP-seq
MIRT1109268	hsa-miR-152	CLIP-seq
MIRT1109269	hsa-miR-1825	CLIP-seq
MIRT1109270	hsa-miR-199a-3p	CLIP-seq
MIRT1109271	hsa-miR-199a-5p	CLIP-seq
MIRT1109272	hsa-miR-199b-3p	CLIP-seq
MIRT1109273	hsa-miR-199b-5p	CLIP-seq
MIRT1109274	hsa-miR-2054	CLIP-seq
MIRT1109275	hsa-miR-2355-3p	CLIP-seq
MIRT1109276	hsa-miR-301a	CLIP-seq
MIRT1109277	hsa-miR-301b	CLIP-seq
MIRT1109278	hsa-miR-3120-5p	CLIP-seq
MIRT1109279	hsa-miR-3129-5p	CLIP-seq
MIRT1109280	hsa-miR-3165	CLIP-seq
MIRT1109281	hsa-miR-3183	CLIP-seq
MIRT1109282	hsa-miR-3189-3p	CLIP-seq
MIRT1109283	hsa-miR-3198	CLIP-seq
MIRT1109284	hsa-miR-33a	CLIP-seq
MIRT1109285	hsa-miR-33b	CLIP-seq
MIRT1109286	hsa-miR-3545-5p	CLIP-seq
MIRT1109287	hsa-miR-3607-3p	CLIP-seq
MIRT1109288	hsa-miR-3664-3p	CLIP-seq
MIRT1109289	hsa-miR-3664-5p	CLIP-seq
MIRT1109290	hsa-miR-3666	CLIP-seq
MIRT1109291	hsa-miR-3670	CLIP-seq
MIRT1109292	hsa-miR-3686	CLIP-seq
MIRT1109293	hsa-miR-3692	CLIP-seq
MIRT1109294	hsa-miR-371-5p	CLIP-seq
MIRT1109295	hsa-miR-371b-5p	CLIP-seq
MIRT1109296	hsa-miR-3909	CLIP-seq
MIRT1109297	hsa-miR-3911	CLIP-seq
MIRT1109298	hsa-miR-3929	CLIP-seq
MIRT1109299	hsa-miR-4269	CLIP-seq
MIRT1109300	hsa-miR-4276	CLIP-seq
MIRT1109301	hsa-miR-4295	CLIP-seq
MIRT1109302	hsa-miR-4302	CLIP-seq
MIRT1109303	hsa-miR-4309	CLIP-seq
MIRT1109304	hsa-miR-432	CLIP-seq
MIRT1109305	hsa-miR-4324	CLIP-seq
MIRT1109306	hsa-miR-4419b	CLIP-seq
MIRT1109307	hsa-miR-4432	CLIP-seq
MIRT1109308	hsa-miR-4433	CLIP-seq
MIRT1109309	hsa-miR-4438	CLIP-seq
MIRT1109310	hsa-miR-4456	CLIP-seq
MIRT1109311	hsa-miR-4459	CLIP-seq
MIRT1109312	hsa-miR-4478	CLIP-seq
MIRT1109313	hsa-miR-4522	CLIP-seq
MIRT1109314	hsa-miR-454	CLIP-seq
MIRT1109315	hsa-miR-4653-3p	CLIP-seq
MIRT1109316	hsa-miR-4695-5p	CLIP-seq
MIRT1109317	hsa-miR-4696	CLIP-seq
MIRT1109318	hsa-miR-4698	CLIP-seq
MIRT1109319	hsa-miR-4715-3p	CLIP-seq
MIRT1109320	hsa-miR-4722-3p	CLIP-seq
MIRT1109321	hsa-miR-4723-3p	CLIP-seq
MIRT1109322	hsa-miR-4724-3p	CLIP-seq
MIRT1109323	hsa-miR-4755-3p	CLIP-seq
MIRT1109324	hsa-miR-4768-3p	CLIP-seq
MIRT1109325	hsa-miR-4790-3p	CLIP-seq
MIRT1109326	hsa-miR-4797-3p	CLIP-seq
MIRT1109327	hsa-miR-485-5p	CLIP-seq
MIRT1109328	hsa-miR-500a	CLIP-seq
MIRT1109329	hsa-miR-5095	CLIP-seq
MIRT1109330	hsa-miR-510	CLIP-seq
MIRT1109331	hsa-miR-512-5p	CLIP-seq
MIRT1109332	hsa-miR-548c-3p	CLIP-seq
MIRT1109333	hsa-miR-591	CLIP-seq
MIRT1109334	hsa-miR-644	CLIP-seq
MIRT1109335	hsa-miR-663b	CLIP-seq
MIRT1109336	hsa-miR-676	CLIP-seq
MIRT1109337	hsa-miR-936	CLIP-seq
MIRT2030353	hsa-miR-103a	CLIP-seq
MIRT2030354	hsa-miR-107	CLIP-seq
MIRT2030355	hsa-miR-122	CLIP-seq
MIRT2030356	hsa-miR-1228	CLIP-seq
MIRT2030357	hsa-miR-1245b-3p	CLIP-seq
MIRT2030358	hsa-miR-1301	CLIP-seq
MIRT2030359	hsa-miR-137	CLIP-seq
MIRT1109270	hsa-miR-199a-3p	CLIP-seq
MIRT1109272	hsa-miR-199b-3p	CLIP-seq
MIRT2030360	hsa-miR-25	CLIP-seq
MIRT2030361	hsa-miR-2861	CLIP-seq
MIRT1109279	hsa-miR-3129-5p	CLIP-seq
MIRT2030362	hsa-miR-3152-5p	CLIP-seq
MIRT2030363	hsa-miR-3187-3p	CLIP-seq
MIRT2030364	hsa-miR-32	CLIP-seq
MIRT2030365	hsa-miR-363	CLIP-seq
MIRT2030366	hsa-miR-367	CLIP-seq
MIRT1109291	hsa-miR-3670	CLIP-seq
MIRT2030367	hsa-miR-3688-3p	CLIP-seq
MIRT1109297	hsa-miR-3911	CLIP-seq
MIRT2030368	hsa-miR-4291	CLIP-seq
MIRT1109305	hsa-miR-4324	CLIP-seq
MIRT2030369	hsa-miR-4435	CLIP-seq
MIRT2030370	hsa-miR-4701-5p	CLIP-seq
MIRT2030371	hsa-miR-4716-5p	CLIP-seq
MIRT2030372	hsa-miR-4774-3p	CLIP-seq
MIRT1109326	hsa-miR-4797-3p	CLIP-seq
MIRT2030373	hsa-miR-5047	CLIP-seq
MIRT2030374	hsa-miR-544b	CLIP-seq
MIRT2030375	hsa-miR-545	CLIP-seq
MIRT2030376	hsa-miR-548s	CLIP-seq
MIRT2030377	hsa-miR-574-5p	CLIP-seq
MIRT2030378	hsa-miR-588	CLIP-seq
MIRT2030379	hsa-miR-765	CLIP-seq
MIRT2030380	hsa-miR-92a	CLIP-seq
MIRT2030381	hsa-miR-92b	CLIP-seq
MIRT1109337	hsa-miR-936	CLIP-seq
MIRT2030353	hsa-miR-103a	CLIP-seq
MIRT2030354	hsa-miR-107	CLIP-seq
MIRT2261073	hsa-miR-1200	CLIP-seq
MIRT2261074	hsa-miR-1229	CLIP-seq
MIRT2030357	hsa-miR-1245b-3p	CLIP-seq
MIRT2030358	hsa-miR-1301	CLIP-seq
MIRT1109262	hsa-miR-130a	CLIP-seq
MIRT1109263	hsa-miR-130b	CLIP-seq
MIRT2261075	hsa-miR-1343	CLIP-seq
MIRT2030359	hsa-miR-137	CLIP-seq
MIRT2261076	hsa-miR-150	CLIP-seq
MIRT2261077	hsa-miR-1915	CLIP-seq
MIRT2261078	hsa-miR-1976	CLIP-seq
MIRT2261079	hsa-miR-2117	CLIP-seq
MIRT2030360	hsa-miR-25	CLIP-seq
MIRT1109276	hsa-miR-301a	CLIP-seq
MIRT1109277	hsa-miR-301b	CLIP-seq
MIRT2261080	hsa-miR-3186-3p	CLIP-seq
MIRT2030364	hsa-miR-32	CLIP-seq
MIRT2030365	hsa-miR-363	CLIP-seq
MIRT1109290	hsa-miR-3666	CLIP-seq
MIRT2030366	hsa-miR-367	CLIP-seq
MIRT2030367	hsa-miR-3688-3p	CLIP-seq
MIRT2261081	hsa-miR-409-3p	CLIP-seq
MIRT2261082	hsa-miR-411	CLIP-seq
MIRT1109299	hsa-miR-4269	CLIP-seq
MIRT2261083	hsa-miR-4273	CLIP-seq
MIRT2261084	hsa-miR-4279	CLIP-seq
MIRT1109301	hsa-miR-4295	CLIP-seq
MIRT2261085	hsa-miR-4307	CLIP-seq
MIRT1109305	hsa-miR-4324	CLIP-seq
MIRT1109308	hsa-miR-4433	CLIP-seq
MIRT1109309	hsa-miR-4438	CLIP-seq
MIRT1109311	hsa-miR-4459	CLIP-seq
MIRT1109314	hsa-miR-454	CLIP-seq
MIRT2261086	hsa-miR-4659a-5p	CLIP-seq
MIRT2261087	hsa-miR-4659b-5p	CLIP-seq
MIRT2261088	hsa-miR-4662a-5p	CLIP-seq
MIRT2261089	hsa-miR-4713-5p	CLIP-seq
MIRT2261090	hsa-miR-4714-3p	CLIP-seq
MIRT1109319	hsa-miR-4715-3p	CLIP-seq
MIRT2030371	hsa-miR-4716-5p	CLIP-seq
MIRT1109320	hsa-miR-4722-3p	CLIP-seq
MIRT2261091	hsa-miR-4726-3p	CLIP-seq
MIRT2261092	hsa-miR-4731-3p	CLIP-seq
MIRT2261093	hsa-miR-4743	CLIP-seq
MIRT1109324	hsa-miR-4768-3p	CLIP-seq
MIRT2261094	hsa-miR-4776-3p	CLIP-seq
MIRT2261095	hsa-miR-4781-3p	CLIP-seq
MIRT2261096	hsa-miR-4789-5p	CLIP-seq
MIRT2261097	hsa-miR-4796-5p	CLIP-seq
MIRT2261098	hsa-miR-4798-3p	CLIP-seq
MIRT2261099	hsa-miR-4801	CLIP-seq
MIRT2261100	hsa-miR-483-5p	CLIP-seq
MIRT2261101	hsa-miR-498	CLIP-seq
MIRT2030373	hsa-miR-5047	CLIP-seq
MIRT1109329	hsa-miR-5095	CLIP-seq
MIRT2261102	hsa-miR-513b	CLIP-seq
MIRT2261103	hsa-miR-532-3p	CLIP-seq
MIRT2030374	hsa-miR-544b	CLIP-seq
MIRT2261104	hsa-miR-566	CLIP-seq
MIRT2261105	hsa-miR-601	CLIP-seq
MIRT2261106	hsa-miR-652	CLIP-seq
MIRT2030380	hsa-miR-92a	CLIP-seq
MIRT2030381	hsa-miR-92b	CLIP-seq
MIRT1109288	hsa-miR-3664-3p	CLIP-seq
MIRT1109298	hsa-miR-3929	CLIP-seq
MIRT1109306	hsa-miR-4419b	CLIP-seq
MIRT1109308	hsa-miR-4433	CLIP-seq
MIRT1109311	hsa-miR-4459	CLIP-seq
MIRT1109312	hsa-miR-4478	CLIP-seq
MIRT1109316	hsa-miR-4695-5p	CLIP-seq
MIRT1109324	hsa-miR-4768-3p	CLIP-seq
MIRT1109327	hsa-miR-485-5p	CLIP-seq
MIRT1109328	hsa-miR-500a	CLIP-seq
MIRT1109330	hsa-miR-510	CLIP-seq
MIRT1109331	hsa-miR-512-5p	CLIP-seq
MIRT2261073	hsa-miR-1200	CLIP-seq
MIRT2261076	hsa-miR-150	CLIP-seq
MIRT2261077	hsa-miR-1915	CLIP-seq
MIRT2261078	hsa-miR-1976	CLIP-seq
MIRT2561100	hsa-miR-2052	CLIP-seq
MIRT2561101	hsa-miR-3149	CLIP-seq
MIRT1109288	hsa-miR-3664-3p	CLIP-seq
MIRT1109298	hsa-miR-3929	CLIP-seq
MIRT2261081	hsa-miR-409-3p	CLIP-seq
MIRT2261082	hsa-miR-411	CLIP-seq
MIRT1109299	hsa-miR-4269	CLIP-seq
MIRT2261084	hsa-miR-4279	CLIP-seq
MIRT2261085	hsa-miR-4307	CLIP-seq
MIRT1109305	hsa-miR-4324	CLIP-seq
MIRT1109306	hsa-miR-4419b	CLIP-seq
MIRT1109308	hsa-miR-4433	CLIP-seq
MIRT1109309	hsa-miR-4438	CLIP-seq
MIRT1109311	hsa-miR-4459	CLIP-seq
MIRT1109312	hsa-miR-4478	CLIP-seq
MIRT1109316	hsa-miR-4695-5p	CLIP-seq
MIRT2261089	hsa-miR-4713-5p	CLIP-seq
MIRT1109319	hsa-miR-4715-3p	CLIP-seq
MIRT1109320	hsa-miR-4722-3p	CLIP-seq
MIRT2261091	hsa-miR-4726-3p	CLIP-seq
MIRT1109324	hsa-miR-4768-3p	CLIP-seq
MIRT1109327	hsa-miR-485-5p	CLIP-seq
MIRT2261101	hsa-miR-498	CLIP-seq
MIRT1109328	hsa-miR-500a	CLIP-seq
MIRT1109329	hsa-miR-5095	CLIP-seq
MIRT1109330	hsa-miR-510	CLIP-seq
MIRT1109331	hsa-miR-512-5p	CLIP-seq
MIRT2261103	hsa-miR-532-3p	CLIP-seq
MIRT2030374	hsa-miR-544b	CLIP-seq
MIRT2261073	hsa-miR-1200	CLIP-seq
MIRT2261076	hsa-miR-150	CLIP-seq
MIRT2261077	hsa-miR-1915	CLIP-seq
MIRT2261078	hsa-miR-1976	CLIP-seq
MIRT2561100	hsa-miR-2052	CLIP-seq
MIRT1109288	hsa-miR-3664-3p	CLIP-seq
MIRT1109298	hsa-miR-3929	CLIP-seq
MIRT2261081	hsa-miR-409-3p	CLIP-seq
MIRT1109299	hsa-miR-4269	CLIP-seq
MIRT2261084	hsa-miR-4279	CLIP-seq
MIRT2261085	hsa-miR-4307	CLIP-seq
MIRT1109305	hsa-miR-4324	CLIP-seq
MIRT1109306	hsa-miR-4419b	CLIP-seq
MIRT1109308	hsa-miR-4433	CLIP-seq
MIRT1109309	hsa-miR-4438	CLIP-seq
MIRT1109311	hsa-miR-4459	CLIP-seq
MIRT1109312	hsa-miR-4478	CLIP-seq
MIRT1109316	hsa-miR-4695-5p	CLIP-seq
MIRT2261089	hsa-miR-4713-5p	CLIP-seq
MIRT1109319	hsa-miR-4715-3p	CLIP-seq
MIRT1109320	hsa-miR-4722-3p	CLIP-seq
MIRT2261091	hsa-miR-4726-3p	CLIP-seq
MIRT1109324	hsa-miR-4768-3p	CLIP-seq
MIRT1109327	hsa-miR-485-5p	CLIP-seq
MIRT2261101	hsa-miR-498	CLIP-seq
MIRT1109328	hsa-miR-500a	CLIP-seq
MIRT1109329	hsa-miR-5095	CLIP-seq
MIRT1109330	hsa-miR-510	CLIP-seq
MIRT1109331	hsa-miR-512-5p	CLIP-seq
MIRT2261103	hsa-miR-532-3p	CLIP-seq
MIRT2030374	hsa-miR-544b	CLIP-seq

Show/Hide all (8)

GO ID	Ontology	Definition	Evidence
GO:0002250	Process	Adaptive immune response	IEA
GO:0002376	Process	Immune system process	IEA
GO:0002764	Process	Immune response-regulating signaling pathway	IBA
GO:0005886	Component	Plasma membrane	IBA
GO:0007166	Process	Cell surface receptor signaling pathway	IEA
GO:0016020	Component	Membrane	IEA
GO:0019221	Process	Cytokine-mediated signaling pathway	IBA
GO:0032396	Function	Inhibitory MHC class I receptor activity	IBA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q6PI73

Protein name

Leukocyte immunoglobulin-like receptor subfamily A member 6 (Immunoglobulin-like transcript 8) (ILT-8) (Leukocyte Ig-like receptor)

Protein function

May act as receptor for class I MHC antigens.

PDB

8GRX

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13895	Ig_2	28 → 117	Immunoglobulin domain	Domain
PF00047	ig	328 → 411	Immunoglobulin domain	Domain

Sequence

MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSLEAQEYQL
DKEGSPEPLDRNNPLEPKNKARFSIPSMTQHHAGRYRCHYYSSAGWSEPSDPLELVMTGF
YNKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQAL
FPVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQS
LTLQCGSDVGYDRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRCYGAH
NLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSRGYFDTFLLTKEG
AAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSFPSEPLELMVSG
HSGGSSLPPTGPPSTPASHAKDYTVENLIRMGMAGLVLVFLGILLFEAQHSQRNPQDAAG
R

Sequence length

481

Interactions

View interactions

	KEGG
	Osteoclast differentiation B cell receptor signaling pathway

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (8)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Clear cell carcinoma of kidney	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colon adenocarcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUNG DISEASES	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant lymphoma, large B-cell, diffuse	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Nonpapillary renal cell carcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thymoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (20)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Breast Neoplasms	Breast neoplasm	Pubtator	26769854	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	35321724	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Ovarian Epithelial	Epithelial ovarian carcinoma	Pubtator	30948450	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	35377522	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Critical Illness	Critical illness	Pubtator	38275610	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Degenerative polyarthritis	Arthritis	BEFREE	25525593		★★★★★ ★☆☆☆☆ Found in Text Mining only
Dermatitis Atopic	Atopic dermatitis	Pubtator	27333811	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Dermatitis, Atopic	Dermatitis	BEFREE	27333811		★★★★★ ★☆☆☆☆ Found in Text Mining only
Eczema	Eczema	BEFREE	27333811		★★★★★ ★☆☆☆☆ Found in Text Mining only
Idiopathic Pulmonary Fibrosis	Pulmonary Fibrosis	BEFREE	23258232		★★★★★ ★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory bowel disease	Pubtator	40054016	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	31700117		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mitochondrial Diseases	Mitochondrial disease	Pubtator	37335462	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasopharyngeal Carcinoma	Nasopharyngeal carcinoma	Pubtator	26730743	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Necrosis	Necrosis	Pubtator	26769854	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pheochromocytoma	Pheochromocytoma	Pubtator	33795528	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Rheumatoid Arthritis	Rheumatoid arthritis	BEFREE	26805457		★★★★★ ★☆☆☆☆ Found in Text Mining only
Septicemia	Septicemia	BEFREE	31250008		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stroke	Stroke	Pubtator	37335462	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Takayasu Arteritis	Takayasu Arteritis	BEFREE	25604533, 27769046		★★★★★ ★☆☆☆☆ Found in Text Mining only

LILRA6 (leukocyte immunoglobulin like receptor A6)