Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	79089
Gene name	Transmembrane and ubiquitin like domain containing 2
Gene symbol	TMUB2
Synonyms (NCBI Gene)	FP2653
Chromosome	17
Chromosome location	17q21.31

162

Show/Hide all (162)

miRTarBase ID	miRNA	Experiments	Reference
MIRT025707	hsa-miR-7-5p	Sequencing	20371350
MIRT031324	hsa-miR-18a-5p	Sequencing	20371350
MIRT1441717	hsa-miR-106a	CLIP-seq
MIRT1441718	hsa-miR-106b	CLIP-seq
MIRT1441719	hsa-miR-1200	CLIP-seq
MIRT1441720	hsa-miR-1252	CLIP-seq
MIRT1441721	hsa-miR-140-3p	CLIP-seq
MIRT1441722	hsa-miR-17	CLIP-seq
MIRT1441723	hsa-miR-20a	CLIP-seq
MIRT1441724	hsa-miR-20b	CLIP-seq
MIRT1441725	hsa-miR-216a	CLIP-seq
MIRT1441726	hsa-miR-302a	CLIP-seq
MIRT1441727	hsa-miR-302b	CLIP-seq
MIRT1441728	hsa-miR-302c	CLIP-seq
MIRT1441729	hsa-miR-302d	CLIP-seq
MIRT1441730	hsa-miR-302e	CLIP-seq
MIRT1441731	hsa-miR-3136-5p	CLIP-seq
MIRT1441732	hsa-miR-3163	CLIP-seq
MIRT1441733	hsa-miR-3662	CLIP-seq
MIRT1441734	hsa-miR-3670	CLIP-seq
MIRT1441735	hsa-miR-3689a-3p	CLIP-seq
MIRT1441736	hsa-miR-3689c	CLIP-seq
MIRT1441737	hsa-miR-372	CLIP-seq
MIRT1441738	hsa-miR-373	CLIP-seq
MIRT1441739	hsa-miR-4439	CLIP-seq
MIRT1441740	hsa-miR-4513	CLIP-seq
MIRT1441741	hsa-miR-4728-5p	CLIP-seq
MIRT1441742	hsa-miR-519d	CLIP-seq
MIRT1441743	hsa-miR-520a-3p	CLIP-seq
MIRT1441744	hsa-miR-520b	CLIP-seq
MIRT1441745	hsa-miR-520c-3p	CLIP-seq
MIRT1441746	hsa-miR-520d-3p	CLIP-seq
MIRT1441747	hsa-miR-520e	CLIP-seq
MIRT1441748	hsa-miR-520f	CLIP-seq
MIRT1441749	hsa-miR-520g	CLIP-seq
MIRT1441750	hsa-miR-520h	CLIP-seq
MIRT1441751	hsa-miR-552	CLIP-seq
MIRT1441752	hsa-miR-93	CLIP-seq
MIRT1441719	hsa-miR-1200	CLIP-seq
MIRT1441720	hsa-miR-1252	CLIP-seq
MIRT1441753	hsa-miR-199a-5p	CLIP-seq
MIRT1441754	hsa-miR-199b-5p	CLIP-seq
MIRT1441755	hsa-miR-3127-3p	CLIP-seq
MIRT1441731	hsa-miR-3136-5p	CLIP-seq
MIRT1441732	hsa-miR-3163	CLIP-seq
MIRT1441756	hsa-miR-3189-5p	CLIP-seq
MIRT1441757	hsa-miR-3202	CLIP-seq
MIRT1441758	hsa-miR-3667-3p	CLIP-seq
MIRT1441734	hsa-miR-3670	CLIP-seq
MIRT1441759	hsa-miR-371-5p	CLIP-seq
MIRT1441760	hsa-miR-371b-5p	CLIP-seq
MIRT1441761	hsa-miR-4251	CLIP-seq
MIRT1441762	hsa-miR-4258	CLIP-seq
MIRT1441763	hsa-miR-4302	CLIP-seq
MIRT1441739	hsa-miR-4439	CLIP-seq
MIRT1441740	hsa-miR-4513	CLIP-seq
MIRT1441764	hsa-miR-4533	CLIP-seq
MIRT1441765	hsa-miR-4694-3p	CLIP-seq
MIRT1441766	hsa-miR-4758-3p	CLIP-seq
MIRT1441767	hsa-miR-496	CLIP-seq
MIRT1441768	hsa-miR-539	CLIP-seq
MIRT1441769	hsa-miR-622	CLIP-seq
MIRT1441770	hsa-miR-647	CLIP-seq
MIRT1441771	hsa-miR-3155	CLIP-seq
MIRT1441772	hsa-miR-3155b	CLIP-seq
MIRT1441773	hsa-miR-4286	CLIP-seq
MIRT1441774	hsa-miR-484	CLIP-seq
MIRT1441725	hsa-miR-216a	CLIP-seq
MIRT1441741	hsa-miR-4728-5p	CLIP-seq
MIRT2646993	hsa-miR-1253	CLIP-seq
MIRT2646994	hsa-miR-1255a	CLIP-seq
MIRT2646995	hsa-miR-1255b	CLIP-seq
MIRT2646996	hsa-miR-1298	CLIP-seq
MIRT2646997	hsa-miR-1914	CLIP-seq
MIRT1441753	hsa-miR-199a-5p	CLIP-seq
MIRT1441754	hsa-miR-199b-5p	CLIP-seq
MIRT2646998	hsa-miR-218	CLIP-seq
MIRT2646999	hsa-miR-219-1-3p	CLIP-seq
MIRT2647000	hsa-miR-22	CLIP-seq
MIRT2647001	hsa-miR-3126-5p	CLIP-seq
MIRT2647002	hsa-miR-3145-5p	CLIP-seq
MIRT2647003	hsa-miR-3154	CLIP-seq
MIRT1441771	hsa-miR-3155	CLIP-seq
MIRT1441772	hsa-miR-3155b	CLIP-seq
MIRT2647004	hsa-miR-3160-3p	CLIP-seq
MIRT2647005	hsa-miR-3162-3p	CLIP-seq
MIRT2647006	hsa-miR-3179	CLIP-seq
MIRT1441757	hsa-miR-3202	CLIP-seq
MIRT2647007	hsa-miR-3691-5p	CLIP-seq
MIRT1441759	hsa-miR-371-5p	CLIP-seq
MIRT1441760	hsa-miR-371b-5p	CLIP-seq
MIRT2647008	hsa-miR-3913-3p	CLIP-seq
MIRT1441761	hsa-miR-4251	CLIP-seq
MIRT1441762	hsa-miR-4258	CLIP-seq
MIRT1441763	hsa-miR-4302	CLIP-seq
MIRT2647009	hsa-miR-4487	CLIP-seq
MIRT1441764	hsa-miR-4533	CLIP-seq
MIRT2647010	hsa-miR-4645-5p	CLIP-seq
MIRT2647011	hsa-miR-4663	CLIP-seq
MIRT2647012	hsa-miR-4673	CLIP-seq
MIRT2647013	hsa-miR-4682	CLIP-seq
MIRT1441765	hsa-miR-4694-3p	CLIP-seq
MIRT2647014	hsa-miR-4728-3p	CLIP-seq
MIRT1441741	hsa-miR-4728-5p	CLIP-seq
MIRT2647015	hsa-miR-4731-5p	CLIP-seq
MIRT2647016	hsa-miR-4752	CLIP-seq
MIRT1441774	hsa-miR-484	CLIP-seq
MIRT2647017	hsa-miR-489	CLIP-seq
MIRT1441767	hsa-miR-496	CLIP-seq
MIRT2647018	hsa-miR-508-5p	CLIP-seq
MIRT1441768	hsa-miR-539	CLIP-seq
MIRT2647019	hsa-miR-558	CLIP-seq
MIRT2647020	hsa-miR-571	CLIP-seq
MIRT1441769	hsa-miR-622	CLIP-seq
MIRT1441770	hsa-miR-647	CLIP-seq
MIRT2647021	hsa-miR-938	CLIP-seq
MIRT2646993	hsa-miR-1253	CLIP-seq
MIRT2646994	hsa-miR-1255a	CLIP-seq
MIRT2646995	hsa-miR-1255b	CLIP-seq
MIRT2646996	hsa-miR-1298	CLIP-seq
MIRT2646997	hsa-miR-1914	CLIP-seq
MIRT1441753	hsa-miR-199a-5p	CLIP-seq
MIRT1441754	hsa-miR-199b-5p	CLIP-seq
MIRT2646998	hsa-miR-218	CLIP-seq
MIRT2646999	hsa-miR-219-1-3p	CLIP-seq
MIRT2647000	hsa-miR-22	CLIP-seq
MIRT2647001	hsa-miR-3126-5p	CLIP-seq
MIRT2647002	hsa-miR-3145-5p	CLIP-seq
MIRT2647003	hsa-miR-3154	CLIP-seq
MIRT1441771	hsa-miR-3155	CLIP-seq
MIRT1441772	hsa-miR-3155b	CLIP-seq
MIRT2647004	hsa-miR-3160-3p	CLIP-seq
MIRT2647005	hsa-miR-3162-3p	CLIP-seq
MIRT2647006	hsa-miR-3179	CLIP-seq
MIRT1441757	hsa-miR-3202	CLIP-seq
MIRT2647007	hsa-miR-3691-5p	CLIP-seq
MIRT1441759	hsa-miR-371-5p	CLIP-seq
MIRT1441760	hsa-miR-371b-5p	CLIP-seq
MIRT2647008	hsa-miR-3913-3p	CLIP-seq
MIRT1441761	hsa-miR-4251	CLIP-seq
MIRT1441762	hsa-miR-4258	CLIP-seq
MIRT1441763	hsa-miR-4302	CLIP-seq
MIRT2647009	hsa-miR-4487	CLIP-seq
MIRT1441764	hsa-miR-4533	CLIP-seq
MIRT2647010	hsa-miR-4645-5p	CLIP-seq
MIRT2647011	hsa-miR-4663	CLIP-seq
MIRT2647012	hsa-miR-4673	CLIP-seq
MIRT2647013	hsa-miR-4682	CLIP-seq
MIRT1441765	hsa-miR-4694-3p	CLIP-seq
MIRT2647014	hsa-miR-4728-3p	CLIP-seq
MIRT1441741	hsa-miR-4728-5p	CLIP-seq
MIRT2647015	hsa-miR-4731-5p	CLIP-seq
MIRT2647016	hsa-miR-4752	CLIP-seq
MIRT1441774	hsa-miR-484	CLIP-seq
MIRT2647017	hsa-miR-489	CLIP-seq
MIRT1441767	hsa-miR-496	CLIP-seq
MIRT2647018	hsa-miR-508-5p	CLIP-seq
MIRT1441768	hsa-miR-539	CLIP-seq
MIRT2647019	hsa-miR-558	CLIP-seq
MIRT2647020	hsa-miR-571	CLIP-seq
MIRT1441769	hsa-miR-622	CLIP-seq
MIRT1441770	hsa-miR-647	CLIP-seq

Show/Hide all (4)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 32296183, 32814053
GO:0016020	Component	Membrane	IEA
GO:0036503	Process	ERAD pathway	IBA
GO:0036503	Process	ERAD pathway	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q71RG4

Protein name

Transmembrane and ubiquitin-like domain-containing protein 2

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00240	ubiquitin	174 → 245	Ubiquitin family	Domain

Sequence

MISRHLQNNLMSVDPASSQAMELSDVTLIEGVGNEVMVVAGVVVLILALVLAWLSTYVAD
SGSNQLLGAIVSAGDTSVLHLGHVDHLVAGQGNPEPTELPHPSEGNDEKAEEAGEGRGDS
TGEAGAGGGVEPSLEHLLDIQGLPKRQAGAGSSSPEAPLRSEDSTCLPPSPGLITVRLKF
LNDTEELAVARPEDTVGALKSKYFPGQESQMKLIYQGRLLQDPARTLRSLNITDNCVIHC
HRSPPGSAVPGPSASLAPSATEPPSLGVNVGSLMVPVFVVLLGVVWYFRINYRQFFTAPA
TVSLVGVTVFFSFLVFGMYGR

Sequence length

321

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ALZHEIMER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (1)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Osteoporosis	Osteoporosis	Pubtator	32827035	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

TMUB2 (transmembrane and ubiquitin like domain containing 2)