Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	79080
Gene name	Coiled-coil domain containing 86
Gene symbol	CCDC86
Synonyms (NCBI Gene)	Cgr1
Chromosome	11
Chromosome location	11q12.2

171

Show/Hide all (171)

miRTarBase ID	miRNA	Experiments	Reference
MIRT022797	hsa-miR-124-3p	Proteomics;Microarray	18668037
MIRT049209	hsa-miR-92a-3p	CLASH	23622248
MIRT504903	hsa-miR-1226-3p	PAR-CLIP	23446348
MIRT504902	hsa-miR-4733-3p	PAR-CLIP	23446348
MIRT504901	hsa-miR-3622a-3p	PAR-CLIP	23446348
MIRT504900	hsa-miR-3622b-3p	PAR-CLIP	23446348
MIRT504898	hsa-miR-6765-3p	PAR-CLIP	23446348
MIRT504899	hsa-miR-4704-3p	PAR-CLIP	23446348
MIRT504897	hsa-miR-4267	PAR-CLIP	23446348
MIRT504896	hsa-miR-4722-3p	PAR-CLIP	23446348
MIRT504895	hsa-miR-6727-3p	PAR-CLIP	23446348
MIRT504903	hsa-miR-1226-3p	PAR-CLIP	23446348
MIRT504902	hsa-miR-4733-3p	PAR-CLIP	23446348
MIRT504901	hsa-miR-3622a-3p	PAR-CLIP	23446348
MIRT504900	hsa-miR-3622b-3p	PAR-CLIP	23446348
MIRT504898	hsa-miR-6765-3p	PAR-CLIP	23446348
MIRT504899	hsa-miR-4704-3p	PAR-CLIP	23446348
MIRT504897	hsa-miR-4267	PAR-CLIP	23446348
MIRT504896	hsa-miR-4722-3p	PAR-CLIP	23446348
MIRT504895	hsa-miR-6727-3p	PAR-CLIP	23446348
MIRT479850	hsa-miR-548az-5p	PAR-CLIP	23592263
MIRT479848	hsa-miR-548t-5p	PAR-CLIP	23592263
MIRT479847	hsa-miR-4796-3p	PAR-CLIP	23592263
MIRT479845	hsa-miR-3125	PAR-CLIP	23592263
MIRT479846	hsa-miR-3916	PAR-CLIP	23592263
MIRT479844	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT479843	hsa-miR-3914	PAR-CLIP	23592263
MIRT479842	hsa-miR-16-1-3p	PAR-CLIP	23592263
MIRT479841	hsa-miR-622	PAR-CLIP	23592263
MIRT479840	hsa-miR-93-3p	PAR-CLIP	23592263
MIRT479839	hsa-miR-3692-5p	PAR-CLIP	23592263
MIRT479838	hsa-miR-3928-3p	PAR-CLIP	23592263
MIRT479837	hsa-miR-4731-5p	PAR-CLIP	23592263
MIRT479836	hsa-miR-5589-5p	PAR-CLIP	23592263
MIRT479835	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT479834	hsa-miR-4306	PAR-CLIP	23592263
MIRT479833	hsa-miR-4644	PAR-CLIP	23592263
MIRT479832	hsa-miR-5192	PAR-CLIP	23592263
MIRT479831	hsa-miR-222-5p	PAR-CLIP	23592263
MIRT479830	hsa-miR-6071	PAR-CLIP	23592263
MIRT479829	hsa-miR-30a-3p	PAR-CLIP	23592263
MIRT479828	hsa-miR-30d-3p	PAR-CLIP	23592263
MIRT479827	hsa-miR-30e-3p	PAR-CLIP	23592263
MIRT504903	hsa-miR-1226-3p	PAR-CLIP	26701625
MIRT504901	hsa-miR-3622a-3p	PAR-CLIP	26701625
MIRT504900	hsa-miR-3622b-3p	PAR-CLIP	26701625
MIRT504897	hsa-miR-4267	PAR-CLIP	26701625
MIRT504899	hsa-miR-4704-3p	PAR-CLIP	26701625
MIRT504896	hsa-miR-4722-3p	PAR-CLIP	26701625
MIRT504902	hsa-miR-4733-3p	PAR-CLIP	26701625
MIRT504895	hsa-miR-6727-3p	PAR-CLIP	26701625
MIRT504898	hsa-miR-6765-3p	PAR-CLIP	26701625
MIRT504903	hsa-miR-1226-3p	PAR-CLIP	23446348
MIRT504902	hsa-miR-4733-3p	PAR-CLIP	23446348
MIRT504901	hsa-miR-3622a-3p	PAR-CLIP	23446348
MIRT504900	hsa-miR-3622b-3p	PAR-CLIP	23446348
MIRT504898	hsa-miR-6765-3p	PAR-CLIP	23446348
MIRT504899	hsa-miR-4704-3p	PAR-CLIP	23446348
MIRT504897	hsa-miR-4267	PAR-CLIP	23446348
MIRT504896	hsa-miR-4722-3p	PAR-CLIP	23446348
MIRT504895	hsa-miR-6727-3p	PAR-CLIP	23446348
MIRT504903	hsa-miR-1226-3p	PAR-CLIP	23446348
MIRT504902	hsa-miR-4733-3p	PAR-CLIP	23446348
MIRT504901	hsa-miR-3622a-3p	PAR-CLIP	23446348
MIRT504900	hsa-miR-3622b-3p	PAR-CLIP	23446348
MIRT504898	hsa-miR-6765-3p	PAR-CLIP	23446348
MIRT504899	hsa-miR-4704-3p	PAR-CLIP	23446348
MIRT504897	hsa-miR-4267	PAR-CLIP	23446348
MIRT504896	hsa-miR-4722-3p	PAR-CLIP	23446348
MIRT504895	hsa-miR-6727-3p	PAR-CLIP	23446348
MIRT479850	hsa-miR-548az-5p	PAR-CLIP	23592263
MIRT479848	hsa-miR-548t-5p	PAR-CLIP	23592263
MIRT479847	hsa-miR-4796-3p	PAR-CLIP	23592263
MIRT479845	hsa-miR-3125	PAR-CLIP	23592263
MIRT479846	hsa-miR-3916	PAR-CLIP	23592263
MIRT479844	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT479843	hsa-miR-3914	PAR-CLIP	23592263
MIRT479842	hsa-miR-16-1-3p	PAR-CLIP	23592263
MIRT479841	hsa-miR-622	PAR-CLIP	23592263
MIRT479840	hsa-miR-93-3p	PAR-CLIP	23592263
MIRT479839	hsa-miR-3692-5p	PAR-CLIP	23592263
MIRT479838	hsa-miR-3928-3p	PAR-CLIP	23592263
MIRT479837	hsa-miR-4731-5p	PAR-CLIP	23592263
MIRT479836	hsa-miR-5589-5p	PAR-CLIP	23592263
MIRT479835	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT479834	hsa-miR-4306	PAR-CLIP	23592263
MIRT479833	hsa-miR-4644	PAR-CLIP	23592263
MIRT479832	hsa-miR-5192	PAR-CLIP	23592263
MIRT479831	hsa-miR-222-5p	PAR-CLIP	23592263
MIRT479830	hsa-miR-6071	PAR-CLIP	23592263
MIRT479829	hsa-miR-30a-3p	PAR-CLIP	23592263
MIRT479828	hsa-miR-30d-3p	PAR-CLIP	23592263
MIRT479827	hsa-miR-30e-3p	PAR-CLIP	23592263
MIRT870071	hsa-miR-1207-5p	CLIP-seq
MIRT870072	hsa-miR-1231	CLIP-seq
MIRT870073	hsa-miR-133a	CLIP-seq
MIRT870074	hsa-miR-133b	CLIP-seq
MIRT870075	hsa-miR-136	CLIP-seq
MIRT870076	hsa-miR-1827	CLIP-seq
MIRT870077	hsa-miR-2682	CLIP-seq
MIRT870078	hsa-miR-3144-5p	CLIP-seq
MIRT870079	hsa-miR-3191	CLIP-seq
MIRT870080	hsa-miR-34a	CLIP-seq
MIRT870081	hsa-miR-34c-5p	CLIP-seq
MIRT870082	hsa-miR-3616-3p	CLIP-seq
MIRT870083	hsa-miR-3945	CLIP-seq
MIRT870084	hsa-miR-4251	CLIP-seq
MIRT870085	hsa-miR-4268	CLIP-seq
MIRT870086	hsa-miR-4288	CLIP-seq
MIRT870087	hsa-miR-4307	CLIP-seq
MIRT870088	hsa-miR-4436b-3p	CLIP-seq
MIRT870089	hsa-miR-449a	CLIP-seq
MIRT870090	hsa-miR-449b	CLIP-seq
MIRT870091	hsa-miR-449c	CLIP-seq
MIRT870092	hsa-miR-4652-5p	CLIP-seq
MIRT870093	hsa-miR-4663	CLIP-seq
MIRT870094	hsa-miR-4667-5p	CLIP-seq
MIRT870095	hsa-miR-4700-5p	CLIP-seq
MIRT870096	hsa-miR-4728-3p	CLIP-seq
MIRT870097	hsa-miR-4742-3p	CLIP-seq
MIRT870098	hsa-miR-4761-3p	CLIP-seq
MIRT870099	hsa-miR-4763-3p	CLIP-seq
MIRT870100	hsa-miR-4768-5p	CLIP-seq
MIRT870101	hsa-miR-4795-3p	CLIP-seq
MIRT870102	hsa-miR-539	CLIP-seq
MIRT870103	hsa-miR-601	CLIP-seq
MIRT870104	hsa-miR-632	CLIP-seq
MIRT870105	hsa-miR-9	CLIP-seq
MIRT870071	hsa-miR-1207-5p	CLIP-seq
MIRT1958322	hsa-miR-1236	CLIP-seq
MIRT1958323	hsa-miR-129-5p	CLIP-seq
MIRT1958324	hsa-miR-151-3p	CLIP-seq
MIRT1958325	hsa-miR-1915	CLIP-seq
MIRT1958326	hsa-miR-216b	CLIP-seq
MIRT1958327	hsa-miR-3160-3p	CLIP-seq
MIRT1958328	hsa-miR-3194-3p	CLIP-seq
MIRT870082	hsa-miR-3616-3p	CLIP-seq
MIRT1958329	hsa-miR-4258	CLIP-seq
MIRT870085	hsa-miR-4268	CLIP-seq
MIRT1958330	hsa-miR-4300	CLIP-seq
MIRT870088	hsa-miR-4436b-3p	CLIP-seq
MIRT1958331	hsa-miR-4463	CLIP-seq
MIRT1958332	hsa-miR-4499	CLIP-seq
MIRT870094	hsa-miR-4667-5p	CLIP-seq
MIRT870095	hsa-miR-4700-5p	CLIP-seq
MIRT1958333	hsa-miR-4718	CLIP-seq
MIRT1958334	hsa-miR-4726-3p	CLIP-seq
MIRT1958335	hsa-miR-4727-5p	CLIP-seq
MIRT1958336	hsa-miR-4755-3p	CLIP-seq
MIRT870099	hsa-miR-4763-3p	CLIP-seq
MIRT1958337	hsa-miR-4769-3p	CLIP-seq
MIRT1958338	hsa-miR-4772-3p	CLIP-seq
MIRT1958339	hsa-miR-767-3p	CLIP-seq
MIRT1958340	hsa-miR-920	CLIP-seq
MIRT870071	hsa-miR-1207-5p	CLIP-seq
MIRT2195101	hsa-miR-1226	CLIP-seq
MIRT870073	hsa-miR-133a	CLIP-seq
MIRT870074	hsa-miR-133b	CLIP-seq
MIRT870075	hsa-miR-136	CLIP-seq
MIRT870082	hsa-miR-3616-3p	CLIP-seq
MIRT2195102	hsa-miR-3915	CLIP-seq
MIRT2195103	hsa-miR-3928	CLIP-seq
MIRT870085	hsa-miR-4268	CLIP-seq
MIRT2195104	hsa-miR-4420	CLIP-seq
MIRT870088	hsa-miR-4436b-3p	CLIP-seq
MIRT870093	hsa-miR-4663	CLIP-seq
MIRT870098	hsa-miR-4761-3p	CLIP-seq
MIRT870099	hsa-miR-4763-3p	CLIP-seq
MIRT870105	hsa-miR-9	CLIP-seq
MIRT870094	hsa-miR-4667-5p	CLIP-seq
MIRT870095	hsa-miR-4700-5p	CLIP-seq

Show/Hide all (12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0005515	Function	Protein binding	IPI	15607035
GO:0005634	Component	Nucleus	IDA	17300783
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005694	Component	Chromosome	IDA	36695333
GO:0005694	Component	Chromosome	IEA
GO:0005730	Component	Nucleolus	IBA
GO:0005730	Component	Nucleolus	IDA	36695333
GO:0005730	Component	Nucleolus	IEA
GO:0007059	Process	Chromosome segregation	IMP	36695333
GO:0140014	Process	Mitotic nuclear division	IMP	36695333

MIM	HGNC	e!Ensembl
611293	28359	ENSG00000110104

Q9H6F5

Protein name

Coiled-coil domain-containing protein 86 (Cytokine-induced protein with coiled-coil domain)

Protein function

Required for proper chromosome segregation during mitosis and error-free mitotic progression.

PDB

8FL0 , 8FL2 , 8FL3 , 8FL4 , 8INK , 8IPD , 8IPX , 8IPY , 8IR1 , 8IR3

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03879	Cgr1	236 → 342	Cgr1 family	Coiled-coil

Sequence

MDTPLRRSRRLGGLRPESPESLTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLGSPE
RPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKP
SEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLE
LTPRAPGSPRGQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKP
KSGRVWKDRSKKRFSQMLQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKERRRQEKKQ
RRAENLKRRLENERKAEVVQVIRNPAKLKRAKKKQLRSIEKRDTLALLQKQPPQQPAAKI

Sequence length

360

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
LYMPHOMA, LARGE B-CELL, DIFFUSE	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (4)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Diffuse Large B-Cell Lymphoma	Diffuse Lymphoma	CTD_human_DG	23828858		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	Pubtator	36695333	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	BEFREE	23439384		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Schizophrenia	Schizophrenia	PSYGENET_DG	23439384		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

CCDC86 (coiled-coil domain containing 86)