Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	79041
Gene name	Transmembrane protein 38A
Gene symbol	TMEM38A
Synonyms (NCBI Gene)	TRIC-ATRICA
Chromosome	19
Chromosome location	19p13.11

223

Show/Hide all (223)

miRTarBase ID	miRNA	Experiments	Reference
MIRT519551	hsa-miR-106a-5p	PAR-CLIP	23446348
MIRT519550	hsa-miR-106b-5p	PAR-CLIP	23446348
MIRT519549	hsa-miR-17-5p	PAR-CLIP	23446348
MIRT519548	hsa-miR-20a-5p	PAR-CLIP	23446348
MIRT519547	hsa-miR-20b-5p	PAR-CLIP	23446348
MIRT519546	hsa-miR-519d-3p	PAR-CLIP	23446348
MIRT519545	hsa-miR-526b-3p	PAR-CLIP	23446348
MIRT519544	hsa-miR-93-5p	PAR-CLIP	23446348
MIRT519543	hsa-miR-302a-3p	PAR-CLIP	23446348
MIRT519542	hsa-miR-302b-3p	PAR-CLIP	23446348
MIRT519541	hsa-miR-302c-3p	PAR-CLIP	23446348
MIRT519540	hsa-miR-302d-3p	PAR-CLIP	23446348
MIRT519539	hsa-miR-302e	PAR-CLIP	23446348
MIRT519538	hsa-miR-372-3p	PAR-CLIP	23446348
MIRT519537	hsa-miR-373-3p	PAR-CLIP	23446348
MIRT519536	hsa-miR-520a-3p	PAR-CLIP	23446348
MIRT519535	hsa-miR-520b	PAR-CLIP	23446348
MIRT519534	hsa-miR-520c-3p	PAR-CLIP	23446348
MIRT519533	hsa-miR-520d-3p	PAR-CLIP	23446348
MIRT519532	hsa-miR-520e	PAR-CLIP	23446348
MIRT519531	hsa-miR-3159	PAR-CLIP	23446348
MIRT519530	hsa-miR-1295b-3p	PAR-CLIP	23446348
MIRT519529	hsa-miR-6807-5p	PAR-CLIP	23446348
MIRT519551	hsa-miR-106a-5p	PAR-CLIP	23446348
MIRT519550	hsa-miR-106b-5p	PAR-CLIP	23446348
MIRT519549	hsa-miR-17-5p	PAR-CLIP	23446348
MIRT519548	hsa-miR-20a-5p	PAR-CLIP	23446348
MIRT519547	hsa-miR-20b-5p	PAR-CLIP	23446348
MIRT519546	hsa-miR-519d-3p	PAR-CLIP	23446348
MIRT519545	hsa-miR-526b-3p	PAR-CLIP	23446348
MIRT519544	hsa-miR-93-5p	PAR-CLIP	23446348
MIRT519543	hsa-miR-302a-3p	PAR-CLIP	23446348
MIRT519542	hsa-miR-302b-3p	PAR-CLIP	23446348
MIRT519541	hsa-miR-302c-3p	PAR-CLIP	23446348
MIRT519540	hsa-miR-302d-3p	PAR-CLIP	23446348
MIRT519539	hsa-miR-302e	PAR-CLIP	23446348
MIRT519538	hsa-miR-372-3p	PAR-CLIP	23446348
MIRT519537	hsa-miR-373-3p	PAR-CLIP	23446348
MIRT519536	hsa-miR-520a-3p	PAR-CLIP	23446348
MIRT519535	hsa-miR-520b	PAR-CLIP	23446348
MIRT519534	hsa-miR-520c-3p	PAR-CLIP	23446348
MIRT519533	hsa-miR-520d-3p	PAR-CLIP	23446348
MIRT519532	hsa-miR-520e	PAR-CLIP	23446348
MIRT519531	hsa-miR-3159	PAR-CLIP	23446348
MIRT519530	hsa-miR-1295b-3p	PAR-CLIP	23446348
MIRT519529	hsa-miR-6807-5p	PAR-CLIP	23446348
MIRT1436887	hsa-miR-106a	CLIP-seq
MIRT1436888	hsa-miR-106b	CLIP-seq
MIRT1436889	hsa-miR-1234	CLIP-seq
MIRT1436890	hsa-miR-1254	CLIP-seq
MIRT1436891	hsa-miR-150	CLIP-seq
MIRT1436892	hsa-miR-17	CLIP-seq
MIRT1436893	hsa-miR-1913	CLIP-seq
MIRT1436894	hsa-miR-20a	CLIP-seq
MIRT1436895	hsa-miR-20b	CLIP-seq
MIRT1436896	hsa-miR-302a	CLIP-seq
MIRT1436897	hsa-miR-302b	CLIP-seq
MIRT1436898	hsa-miR-302c	CLIP-seq
MIRT1436899	hsa-miR-302d	CLIP-seq
MIRT1436900	hsa-miR-3116	CLIP-seq
MIRT1436901	hsa-miR-3156-5p	CLIP-seq
MIRT1436902	hsa-miR-324-3p	CLIP-seq
MIRT1436903	hsa-miR-372	CLIP-seq
MIRT1436904	hsa-miR-373	CLIP-seq
MIRT1436905	hsa-miR-3922-5p	CLIP-seq
MIRT1436906	hsa-miR-4252	CLIP-seq
MIRT1436907	hsa-miR-4484	CLIP-seq
MIRT1436908	hsa-miR-4695-3p	CLIP-seq
MIRT1436909	hsa-miR-4707-3p	CLIP-seq
MIRT1436910	hsa-miR-4740-3p	CLIP-seq
MIRT1436911	hsa-miR-4747-5p	CLIP-seq
MIRT1436912	hsa-miR-4753-5p	CLIP-seq
MIRT1436913	hsa-miR-4772-3p	CLIP-seq
MIRT1436914	hsa-miR-519d	CLIP-seq
MIRT1436915	hsa-miR-520g	CLIP-seq
MIRT1436916	hsa-miR-520h	CLIP-seq
MIRT1436917	hsa-miR-548an	CLIP-seq
MIRT1436918	hsa-miR-550a	CLIP-seq
MIRT1436919	hsa-miR-661	CLIP-seq
MIRT1436920	hsa-miR-767-5p	CLIP-seq
MIRT1436921	hsa-miR-93	CLIP-seq
MIRT1436889	hsa-miR-1234	CLIP-seq
MIRT2130955	hsa-miR-125a-3p	CLIP-seq
MIRT2130956	hsa-miR-1273f	CLIP-seq
MIRT2130957	hsa-miR-149	CLIP-seq
MIRT1436891	hsa-miR-150	CLIP-seq
MIRT1436893	hsa-miR-1913	CLIP-seq
MIRT2130958	hsa-miR-197	CLIP-seq
MIRT2130959	hsa-miR-3064-5p	CLIP-seq
MIRT2130960	hsa-miR-3149	CLIP-seq
MIRT2130961	hsa-miR-3170	CLIP-seq
MIRT1436902	hsa-miR-324-3p	CLIP-seq
MIRT2130962	hsa-miR-3529	CLIP-seq
MIRT2130963	hsa-miR-3545-3p	CLIP-seq
MIRT2130964	hsa-miR-379	CLIP-seq
MIRT2130965	hsa-miR-3934	CLIP-seq
MIRT2130966	hsa-miR-4254	CLIP-seq
MIRT2130967	hsa-miR-4320	CLIP-seq
MIRT2130968	hsa-miR-4451	CLIP-seq
MIRT1436907	hsa-miR-4484	CLIP-seq
MIRT2130969	hsa-miR-4650-3p	CLIP-seq
MIRT2130970	hsa-miR-4680-5p	CLIP-seq
MIRT1436909	hsa-miR-4707-3p	CLIP-seq
MIRT2130971	hsa-miR-4716-5p	CLIP-seq
MIRT2130972	hsa-miR-4722-3p	CLIP-seq
MIRT2130973	hsa-miR-4735-5p	CLIP-seq
MIRT1436910	hsa-miR-4740-3p	CLIP-seq
MIRT2130974	hsa-miR-4775	CLIP-seq
MIRT2130975	hsa-miR-4781-3p	CLIP-seq
MIRT2130976	hsa-miR-4794	CLIP-seq
MIRT2130977	hsa-miR-5096	CLIP-seq
MIRT1436915	hsa-miR-520g	CLIP-seq
MIRT1436916	hsa-miR-520h	CLIP-seq
MIRT1436917	hsa-miR-548an	CLIP-seq
MIRT2130978	hsa-miR-590-3p	CLIP-seq
MIRT2130979	hsa-miR-764	CLIP-seq
MIRT1436887	hsa-miR-106a	CLIP-seq
MIRT1436888	hsa-miR-106b	CLIP-seq
MIRT1436889	hsa-miR-1234	CLIP-seq
MIRT2130955	hsa-miR-125a-3p	CLIP-seq
MIRT2130957	hsa-miR-149	CLIP-seq
MIRT1436891	hsa-miR-150	CLIP-seq
MIRT1436892	hsa-miR-17	CLIP-seq
MIRT1436893	hsa-miR-1913	CLIP-seq
MIRT1436894	hsa-miR-20a	CLIP-seq
MIRT1436895	hsa-miR-20b	CLIP-seq
MIRT1436896	hsa-miR-302a	CLIP-seq
MIRT1436897	hsa-miR-302b	CLIP-seq
MIRT1436898	hsa-miR-302c	CLIP-seq
MIRT1436899	hsa-miR-302d	CLIP-seq
MIRT2130959	hsa-miR-3064-5p	CLIP-seq
MIRT2352201	hsa-miR-3135b	CLIP-seq
MIRT2130960	hsa-miR-3149	CLIP-seq
MIRT2352202	hsa-miR-3187-3p	CLIP-seq
MIRT2352203	hsa-miR-320e	CLIP-seq
MIRT1436902	hsa-miR-324-3p	CLIP-seq
MIRT2352204	hsa-miR-339-3p	CLIP-seq
MIRT2130963	hsa-miR-3545-3p	CLIP-seq
MIRT2352205	hsa-miR-3663-5p	CLIP-seq
MIRT1436903	hsa-miR-372	CLIP-seq
MIRT1436904	hsa-miR-373	CLIP-seq
MIRT2352206	hsa-miR-3926	CLIP-seq
MIRT2130965	hsa-miR-3934	CLIP-seq
MIRT2352207	hsa-miR-4267	CLIP-seq
MIRT2352208	hsa-miR-4435	CLIP-seq
MIRT2352209	hsa-miR-4635	CLIP-seq
MIRT2130970	hsa-miR-4680-5p	CLIP-seq
MIRT2352210	hsa-miR-4701-5p	CLIP-seq
MIRT1436909	hsa-miR-4707-3p	CLIP-seq
MIRT2130973	hsa-miR-4735-5p	CLIP-seq
MIRT2130974	hsa-miR-4775	CLIP-seq
MIRT2130975	hsa-miR-4781-3p	CLIP-seq
MIRT2130976	hsa-miR-4794	CLIP-seq
MIRT1436914	hsa-miR-519d	CLIP-seq
MIRT1436915	hsa-miR-520g	CLIP-seq
MIRT1436916	hsa-miR-520h	CLIP-seq
MIRT2352211	hsa-miR-548s	CLIP-seq
MIRT2352212	hsa-miR-588	CLIP-seq
MIRT2130978	hsa-miR-590-3p	CLIP-seq
MIRT2352213	hsa-miR-671-5p	CLIP-seq
MIRT2130979	hsa-miR-764	CLIP-seq
MIRT1436921	hsa-miR-93	CLIP-seq
MIRT2130957	hsa-miR-149	CLIP-seq
MIRT2130959	hsa-miR-3064-5p	CLIP-seq
MIRT2130960	hsa-miR-3149	CLIP-seq
MIRT2130973	hsa-miR-4735-5p	CLIP-seq
MIRT2130974	hsa-miR-4775	CLIP-seq
MIRT2130976	hsa-miR-4794	CLIP-seq
MIRT2130978	hsa-miR-590-3p	CLIP-seq
MIRT2130957	hsa-miR-149	CLIP-seq
MIRT2130959	hsa-miR-3064-5p	CLIP-seq
MIRT2130960	hsa-miR-3149	CLIP-seq
MIRT2130962	hsa-miR-3529	CLIP-seq
MIRT2130964	hsa-miR-379	CLIP-seq
MIRT2130968	hsa-miR-4451	CLIP-seq
MIRT2130969	hsa-miR-4650-3p	CLIP-seq
MIRT2130973	hsa-miR-4735-5p	CLIP-seq
MIRT2130974	hsa-miR-4775	CLIP-seq
MIRT2130976	hsa-miR-4794	CLIP-seq
MIRT2130978	hsa-miR-590-3p	CLIP-seq
MIRT1436920	hsa-miR-767-5p	CLIP-seq
MIRT2130957	hsa-miR-149	CLIP-seq
MIRT2645992	hsa-miR-1976	CLIP-seq
MIRT2130959	hsa-miR-3064-5p	CLIP-seq
MIRT2130960	hsa-miR-3149	CLIP-seq
MIRT2130962	hsa-miR-3529	CLIP-seq
MIRT2645993	hsa-miR-3607-5p	CLIP-seq
MIRT2645994	hsa-miR-3690	CLIP-seq
MIRT2130964	hsa-miR-379	CLIP-seq
MIRT2130966	hsa-miR-4254	CLIP-seq
MIRT2645995	hsa-miR-4279	CLIP-seq
MIRT2130967	hsa-miR-4320	CLIP-seq
MIRT2130968	hsa-miR-4451	CLIP-seq
MIRT1436907	hsa-miR-4484	CLIP-seq
MIRT2130969	hsa-miR-4650-3p	CLIP-seq
MIRT2130972	hsa-miR-4722-3p	CLIP-seq
MIRT2130973	hsa-miR-4735-5p	CLIP-seq
MIRT1436910	hsa-miR-4740-3p	CLIP-seq
MIRT2130974	hsa-miR-4775	CLIP-seq
MIRT2130976	hsa-miR-4794	CLIP-seq
MIRT1436917	hsa-miR-548an	CLIP-seq
MIRT2130978	hsa-miR-590-3p	CLIP-seq
MIRT1436920	hsa-miR-767-5p	CLIP-seq
MIRT2130957	hsa-miR-149	CLIP-seq
MIRT2645992	hsa-miR-1976	CLIP-seq
MIRT2130959	hsa-miR-3064-5p	CLIP-seq
MIRT2130960	hsa-miR-3149	CLIP-seq
MIRT2130962	hsa-miR-3529	CLIP-seq
MIRT2645993	hsa-miR-3607-5p	CLIP-seq
MIRT2645994	hsa-miR-3690	CLIP-seq
MIRT2130964	hsa-miR-379	CLIP-seq
MIRT2130966	hsa-miR-4254	CLIP-seq
MIRT2645995	hsa-miR-4279	CLIP-seq
MIRT2130967	hsa-miR-4320	CLIP-seq
MIRT2130968	hsa-miR-4451	CLIP-seq
MIRT2130969	hsa-miR-4650-3p	CLIP-seq
MIRT2130972	hsa-miR-4722-3p	CLIP-seq
MIRT2130973	hsa-miR-4735-5p	CLIP-seq
MIRT1436910	hsa-miR-4740-3p	CLIP-seq
MIRT2130974	hsa-miR-4775	CLIP-seq
MIRT2130976	hsa-miR-4794	CLIP-seq
MIRT2130978	hsa-miR-590-3p	CLIP-seq
MIRT1436920	hsa-miR-767-5p	CLIP-seq

Show/Hide all (26)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005267	Function	Potassium channel activity	IEA
GO:0005267	Function	Potassium channel activity	ISS
GO:0005267	Function	Potassium channel activity	TAS	19095005
GO:0005634	Component	Nucleus	IEA
GO:0006811	Process	Monoatomic ion transport	IEA
GO:0006813	Process	Potassium ion transport	IEA
GO:0007029	Process	Endoplasmic reticulum organization	IEA
GO:0010881	Process	Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	IEA
GO:0014808	Process	Release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	IEA
GO:0016020	Component	Membrane	IEA
GO:0016529	Component	Sarcoplasmic reticulum	IEA
GO:0031965	Component	Nuclear membrane	IEA
GO:0031965	Component	Nuclear membrane	ISS
GO:0031965	Component	Nuclear membrane	NAS	19095005
GO:0033017	Component	Sarcoplasmic reticulum membrane	IEA
GO:0033017	Component	Sarcoplasmic reticulum membrane	ISS
GO:0033017	Component	Sarcoplasmic reticulum membrane	NAS	19095005
GO:0034220	Process	Monoatomic ion transmembrane transport	IEA
GO:0042802	Function	Identical protein binding	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0051279	Process	Regulation of release of sequestered calcium ion into cytosol	ISS
GO:0070062	Component	Extracellular exosome	HDA	19056867
GO:0071313	Process	Cellular response to caffeine	IEA
GO:0071805	Process	Potassium ion transmembrane transport	IEA
GO:0071805	Process	Potassium ion transmembrane transport	IEA
GO:0098662	Process	Inorganic cation transmembrane transport	IEA

MIM	HGNC	e!Ensembl
611235	28462	ENSG00000072954

Q9H6F2

Protein name

Trimeric intracellular cation channel type A (TRIC-A) (TRICA) (Transmembrane protein 38A)

Protein function

Intracellular monovalent cation channel required for maintenance of rapid intracellular calcium release. Acts as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores (By similarity). Op

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF05197	TRIC	40 → 231	TRIC channel	Family

Sequence

MELLSALSLGELALSFSRVPLFPVFDLSYFIVSILYLKYEPGAVELSRRHPIASWLCAML
HCFGSYILADLLLGEPLIDYFSNNSSILLASAVWYLIFFCPLDLFYKCVCFLPVKLIFVA
MKEVVRVRKIAVGIHHAHHHYHHGWFVMIATGWVKGSGVALMSNFEQLLRGVWKPETNEI
LHMSFPTKASLYGAILFTLQQTRWLPVSKASLIFIFTLFMVSCKVFLTATHSHSSPFDAL
EGYICPVLFGSACGGDHHHDNHGGSHSGGGPGAQHSAMPAKSKEELSEGSRKKKAKKAD

Sequence length

299

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
AUTISM SPECTRUM DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (2)

Disease Name	Disease (Merged)	Source	PMID	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Essential Hypertension	Hypertension	BEFREE	21803293	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypertensive disease	Hypertension	BEFREE	21803293	★★★★★ ★☆☆☆☆ Found in Text Mining only

TMEM38A (transmembrane protein 38A)