Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	79022
Gene name	Transmembrane protein 106C
Gene symbol	TMEM106C
Synonyms (NCBI Gene)	-
Chromosome	12
Chromosome location	12q13.11

151

Show/Hide all (151)

miRTarBase ID	miRNA	Experiments	Reference
MIRT023669	hsa-miR-1-3p	Microarray	18668037
MIRT550187	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT550186	hsa-miR-4643	PAR-CLIP	21572407
MIRT550185	hsa-miR-4464	PAR-CLIP	21572407
MIRT550184	hsa-miR-4748	PAR-CLIP	21572407
MIRT550183	hsa-miR-329-5p	PAR-CLIP	21572407
MIRT550182	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT550181	hsa-miR-567	PAR-CLIP	21572407
MIRT550180	hsa-miR-466	PAR-CLIP	21572407
MIRT550179	hsa-miR-4789-5p	PAR-CLIP	21572407
MIRT550178	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT550177	hsa-miR-3924	PAR-CLIP	21572407
MIRT550176	hsa-miR-297	PAR-CLIP	21572407
MIRT550175	hsa-miR-6083	PAR-CLIP	21572407
MIRT550187	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT550186	hsa-miR-4643	PAR-CLIP	21572407
MIRT550185	hsa-miR-4464	PAR-CLIP	21572407
MIRT550184	hsa-miR-4748	PAR-CLIP	21572407
MIRT550183	hsa-miR-329-5p	PAR-CLIP	21572407
MIRT550182	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT550181	hsa-miR-567	PAR-CLIP	21572407
MIRT550180	hsa-miR-466	PAR-CLIP	21572407
MIRT550179	hsa-miR-4789-5p	PAR-CLIP	21572407
MIRT550178	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT550177	hsa-miR-3924	PAR-CLIP	21572407
MIRT550176	hsa-miR-297	PAR-CLIP	21572407
MIRT550175	hsa-miR-6083	PAR-CLIP	21572407
MIRT1429733	hsa-miR-1236	CLIP-seq
MIRT1429734	hsa-miR-139-5p	CLIP-seq
MIRT1429735	hsa-miR-147	CLIP-seq
MIRT1429736	hsa-miR-3190	CLIP-seq
MIRT1429737	hsa-miR-3911	CLIP-seq
MIRT1429738	hsa-miR-4438	CLIP-seq
MIRT1429739	hsa-miR-5095	CLIP-seq
MIRT1429740	hsa-miR-644	CLIP-seq
MIRT1429741	hsa-miR-7	CLIP-seq
MIRT1429742	hsa-miR-1292	CLIP-seq
MIRT1429743	hsa-miR-3122	CLIP-seq
MIRT1429744	hsa-miR-3157-3p	CLIP-seq
MIRT1429745	hsa-miR-365	CLIP-seq
MIRT1429746	hsa-miR-374a	CLIP-seq
MIRT1429747	hsa-miR-374b	CLIP-seq
MIRT1429748	hsa-miR-3913-5p	CLIP-seq
MIRT1429749	hsa-miR-4461	CLIP-seq
MIRT1429750	hsa-miR-4471	CLIP-seq
MIRT1429751	hsa-miR-4658	CLIP-seq
MIRT1429752	hsa-miR-4729	CLIP-seq
MIRT1429753	hsa-miR-4758-5p	CLIP-seq
MIRT1429754	hsa-miR-4760-3p	CLIP-seq
MIRT1429755	hsa-miR-4762-5p	CLIP-seq
MIRT1429756	hsa-miR-494	CLIP-seq
MIRT1429757	hsa-miR-587	CLIP-seq
MIRT2128764	hsa-miR-4728-3p	CLIP-seq
MIRT1429733	hsa-miR-1236	CLIP-seq
MIRT1429734	hsa-miR-139-5p	CLIP-seq
MIRT1429738	hsa-miR-4438	CLIP-seq
MIRT2128764	hsa-miR-4728-3p	CLIP-seq
MIRT1429739	hsa-miR-5095	CLIP-seq
MIRT1429756	hsa-miR-494	CLIP-seq
MIRT2643899	hsa-miR-1193	CLIP-seq
MIRT2643900	hsa-miR-1205	CLIP-seq
MIRT1429733	hsa-miR-1236	CLIP-seq
MIRT2643901	hsa-miR-1245b-3p	CLIP-seq
MIRT2643902	hsa-miR-1245b-5p	CLIP-seq
MIRT1429742	hsa-miR-1292	CLIP-seq
MIRT1429734	hsa-miR-139-5p	CLIP-seq
MIRT1429735	hsa-miR-147	CLIP-seq
MIRT2643903	hsa-miR-1827	CLIP-seq
MIRT2643904	hsa-miR-1972	CLIP-seq
MIRT2643905	hsa-miR-198	CLIP-seq
MIRT2643906	hsa-miR-3130-3p	CLIP-seq
MIRT2643907	hsa-miR-3142	CLIP-seq
MIRT2643908	hsa-miR-3183	CLIP-seq
MIRT2643909	hsa-miR-3189-3p	CLIP-seq
MIRT1429736	hsa-miR-3190	CLIP-seq
MIRT2643910	hsa-miR-331-5p	CLIP-seq
MIRT2643911	hsa-miR-3665	CLIP-seq
MIRT1429737	hsa-miR-3911	CLIP-seq
MIRT2643912	hsa-miR-4252	CLIP-seq
MIRT2643913	hsa-miR-4274	CLIP-seq
MIRT2643914	hsa-miR-4281	CLIP-seq
MIRT1429738	hsa-miR-4438	CLIP-seq
MIRT2643915	hsa-miR-4447	CLIP-seq
MIRT1429750	hsa-miR-4471	CLIP-seq
MIRT2643916	hsa-miR-4472	CLIP-seq
MIRT2643917	hsa-miR-4519	CLIP-seq
MIRT2643918	hsa-miR-4650-5p	CLIP-seq
MIRT2643919	hsa-miR-4678	CLIP-seq
MIRT2643920	hsa-miR-4723-3p	CLIP-seq
MIRT2128764	hsa-miR-4728-3p	CLIP-seq
MIRT2643921	hsa-miR-4753-3p	CLIP-seq
MIRT1429754	hsa-miR-4760-3p	CLIP-seq
MIRT2643922	hsa-miR-4768-5p	CLIP-seq
MIRT2643923	hsa-miR-4793-3p	CLIP-seq
MIRT2643924	hsa-miR-483-3p	CLIP-seq
MIRT1429756	hsa-miR-494	CLIP-seq
MIRT2643925	hsa-miR-499-3p	CLIP-seq
MIRT2643926	hsa-miR-499a-3p	CLIP-seq
MIRT1429739	hsa-miR-5095	CLIP-seq
MIRT2643927	hsa-miR-510	CLIP-seq
MIRT2643928	hsa-miR-544	CLIP-seq
MIRT2643929	hsa-miR-548b-3p	CLIP-seq
MIRT2643930	hsa-miR-642a	CLIP-seq
MIRT1429740	hsa-miR-644	CLIP-seq
MIRT2643931	hsa-miR-657	CLIP-seq
MIRT2643932	hsa-miR-668	CLIP-seq
MIRT1429741	hsa-miR-7	CLIP-seq
MIRT2643899	hsa-miR-1193	CLIP-seq
MIRT1429733	hsa-miR-1236	CLIP-seq
MIRT2643901	hsa-miR-1245b-3p	CLIP-seq
MIRT2643902	hsa-miR-1245b-5p	CLIP-seq
MIRT1429742	hsa-miR-1292	CLIP-seq
MIRT1429734	hsa-miR-139-5p	CLIP-seq
MIRT1429735	hsa-miR-147	CLIP-seq
MIRT2643903	hsa-miR-1827	CLIP-seq
MIRT2643904	hsa-miR-1972	CLIP-seq
MIRT2643905	hsa-miR-198	CLIP-seq
MIRT2643906	hsa-miR-3130-3p	CLIP-seq
MIRT2643907	hsa-miR-3142	CLIP-seq
MIRT2643908	hsa-miR-3183	CLIP-seq
MIRT2643909	hsa-miR-3189-3p	CLIP-seq
MIRT1429736	hsa-miR-3190	CLIP-seq
MIRT2643910	hsa-miR-331-5p	CLIP-seq
MIRT1429737	hsa-miR-3911	CLIP-seq
MIRT2643912	hsa-miR-4252	CLIP-seq
MIRT2643913	hsa-miR-4274	CLIP-seq
MIRT2643914	hsa-miR-4281	CLIP-seq
MIRT1429738	hsa-miR-4438	CLIP-seq
MIRT2643915	hsa-miR-4447	CLIP-seq
MIRT1429750	hsa-miR-4471	CLIP-seq
MIRT2643916	hsa-miR-4472	CLIP-seq
MIRT2643917	hsa-miR-4519	CLIP-seq
MIRT2643918	hsa-miR-4650-5p	CLIP-seq
MIRT2643919	hsa-miR-4678	CLIP-seq
MIRT2643920	hsa-miR-4723-3p	CLIP-seq
MIRT2128764	hsa-miR-4728-3p	CLIP-seq
MIRT2643921	hsa-miR-4753-3p	CLIP-seq
MIRT1429754	hsa-miR-4760-3p	CLIP-seq
MIRT2643922	hsa-miR-4768-5p	CLIP-seq
MIRT2643923	hsa-miR-4793-3p	CLIP-seq
MIRT2643924	hsa-miR-483-3p	CLIP-seq
MIRT1429756	hsa-miR-494	CLIP-seq
MIRT2643925	hsa-miR-499-3p	CLIP-seq
MIRT2643926	hsa-miR-499a-3p	CLIP-seq
MIRT1429739	hsa-miR-5095	CLIP-seq
MIRT2643927	hsa-miR-510	CLIP-seq
MIRT2643928	hsa-miR-544	CLIP-seq
MIRT2643929	hsa-miR-548b-3p	CLIP-seq
MIRT2643930	hsa-miR-642a	CLIP-seq
MIRT1429740	hsa-miR-644	CLIP-seq
MIRT1429741	hsa-miR-7	CLIP-seq

Show/Hide all (4)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 32296183, 33961781, 35271311
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0016020	Component	Membrane	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q9BVX2

Protein name

Transmembrane protein 106C (Endoplasmic reticulum membrane protein overexpressed in cancer)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07092	DUF1356	17 → 248	Protein of unknown function (DUF1356)	Family

Sequence

MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI
PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV
VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVSTYVTTNVSLIPPR
SEQLVNFTGKAEMGGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHY
VDCGGNSTAI

Sequence length

250

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
OSTEOARTHRITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS, HIP	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (4)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	33591950	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	34476506, 39380994	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	35924107	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	20687218	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

TMEM106C (transmembrane protein 106C)