SCNM1 (sodium channel modifier 1)

Gene

• Entrez ID: 79005
• Gene name: Sodium channel modifier 1
• Gene symbol: SCNM1
• Synonyms (NCBI Gene): OFD19
• Chromosome: 1
• Chromosome location: 1q21.3
• Summary: SCNM1 is a zinc finger protein and putative splicing factor. In mice, Scnm1 modifies phenotypic expression of Scn8a (MIM 600702) mutations (Buchner et al., 2003 [PubMed 12920299]).[supplied by OMIM, Oct 2009]

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT693128	hsa-miR-4484	HITS-CLIP	23313552
MIRT693127	hsa-miR-510-5p	HITS-CLIP	23313552
MIRT693126	hsa-miR-4695-5p	HITS-CLIP	23313552
MIRT693125	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT693124	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT693123	hsa-miR-940	HITS-CLIP	23313552
MIRT693121	hsa-miR-3929	HITS-CLIP	23313552
MIRT693122	hsa-miR-4419b	HITS-CLIP	23313552
MIRT693120	hsa-miR-4478	HITS-CLIP	23313552
MIRT693119	hsa-miR-3664-3p	HITS-CLIP	23313552
MIRT693118	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT693117	hsa-miR-1827	HITS-CLIP	23313552
MIRT693116	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT693115	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT693114	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT693113	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT693112	hsa-miR-5095	HITS-CLIP	23313552
MIRT693111	hsa-miR-665	HITS-CLIP	23313552
MIRT693110	hsa-miR-6888-5p	HITS-CLIP	23313552
MIRT693109	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT693108	hsa-miR-4459	HITS-CLIP	23313552
MIRT693107	hsa-miR-4433a-3p	HITS-CLIP	23313552
MIRT693106	hsa-miR-6089	HITS-CLIP	23313552
MIRT693105	hsa-miR-6134	HITS-CLIP	23313552
MIRT693104	hsa-miR-4683	HITS-CLIP	23313552
MIRT693103	hsa-miR-7106-5p	HITS-CLIP	23313552
MIRT693102	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT693101	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT693100	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT693099	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT693098	hsa-miR-6799-5p	HITS-CLIP	23313552
MIRT693097	hsa-miR-541-3p	HITS-CLIP	23313552
MIRT693096	hsa-miR-654-5p	HITS-CLIP	23313552
MIRT693095	hsa-miR-30c-1-3p	HITS-CLIP	23313552
MIRT693094	hsa-miR-30c-2-3p	HITS-CLIP	23313552
MIRT693093	hsa-miR-6788-5p	HITS-CLIP	23313552
MIRT693092	hsa-miR-1273h-5p	HITS-CLIP	23313552
MIRT693091	hsa-miR-30b-3p	HITS-CLIP	23313552
MIRT693090	hsa-miR-3689a-3p	HITS-CLIP	23313552
MIRT693089	hsa-miR-3689b-3p	HITS-CLIP	23313552
MIRT693088	hsa-miR-3689c	HITS-CLIP	23313552
MIRT693087	hsa-miR-6779-5p	HITS-CLIP	23313552
MIRT693086	hsa-miR-6780a-5p	HITS-CLIP	23313552
MIRT693085	hsa-miR-1228-5p	HITS-CLIP	23313552
MIRT693084	hsa-miR-450a-1-3p	HITS-CLIP	23313552
MIRT693083	hsa-miR-3122	HITS-CLIP	23313552
MIRT693082	hsa-miR-3913-5p	HITS-CLIP	23313552
MIRT693081	hsa-miR-887-5p	HITS-CLIP	23313552
MIRT693080	hsa-miR-6513-5p	HITS-CLIP	23313552
MIRT693128	hsa-miR-4484	HITS-CLIP	23313552
MIRT693127	hsa-miR-510-5p	HITS-CLIP	23313552
MIRT693126	hsa-miR-4695-5p	HITS-CLIP	23313552
MIRT693125	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT693124	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT693123	hsa-miR-940	HITS-CLIP	23313552
MIRT693121	hsa-miR-3929	HITS-CLIP	23313552
MIRT693122	hsa-miR-4419b	HITS-CLIP	23313552
MIRT693120	hsa-miR-4478	HITS-CLIP	23313552
MIRT693119	hsa-miR-3664-3p	HITS-CLIP	23313552
MIRT693118	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT693117	hsa-miR-1827	HITS-CLIP	23313552
MIRT693116	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT693115	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT693114	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT693113	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT693112	hsa-miR-5095	HITS-CLIP	23313552
MIRT693111	hsa-miR-665	HITS-CLIP	23313552
MIRT693110	hsa-miR-6888-5p	HITS-CLIP	23313552
MIRT693109	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT693108	hsa-miR-4459	HITS-CLIP	23313552
MIRT693107	hsa-miR-4433a-3p	HITS-CLIP	23313552
MIRT693106	hsa-miR-6089	HITS-CLIP	23313552
MIRT693105	hsa-miR-6134	HITS-CLIP	23313552
MIRT693104	hsa-miR-4683	HITS-CLIP	23313552
MIRT693103	hsa-miR-7106-5p	HITS-CLIP	23313552
MIRT693102	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT693101	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT693100	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT693099	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT693098	hsa-miR-6799-5p	HITS-CLIP	23313552
MIRT693097	hsa-miR-541-3p	HITS-CLIP	23313552
MIRT693096	hsa-miR-654-5p	HITS-CLIP	23313552
MIRT693095	hsa-miR-30c-1-3p	HITS-CLIP	23313552
MIRT693094	hsa-miR-30c-2-3p	HITS-CLIP	23313552
MIRT693093	hsa-miR-6788-5p	HITS-CLIP	23313552
MIRT693092	hsa-miR-1273h-5p	HITS-CLIP	23313552
MIRT693091	hsa-miR-30b-3p	HITS-CLIP	23313552
MIRT693090	hsa-miR-3689a-3p	HITS-CLIP	23313552
MIRT693089	hsa-miR-3689b-3p	HITS-CLIP	23313552
MIRT693088	hsa-miR-3689c	HITS-CLIP	23313552
MIRT693087	hsa-miR-6779-5p	HITS-CLIP	23313552
MIRT693086	hsa-miR-6780a-5p	HITS-CLIP	23313552
MIRT693085	hsa-miR-1228-5p	HITS-CLIP	23313552
MIRT693084	hsa-miR-450a-1-3p	HITS-CLIP	23313552
MIRT693083	hsa-miR-3122	HITS-CLIP	23313552
MIRT693082	hsa-miR-3913-5p	HITS-CLIP	23313552
MIRT693081	hsa-miR-887-5p	HITS-CLIP	23313552
MIRT693080	hsa-miR-6513-5p	HITS-CLIP	23313552
MIRT1330324	hsa-miR-1207-5p	CLIP-seq
MIRT1330325	hsa-miR-1285	CLIP-seq
MIRT1330326	hsa-miR-1321	CLIP-seq
MIRT1330327	hsa-miR-146b-3p	CLIP-seq
MIRT1330328	hsa-miR-1908	CLIP-seq
MIRT1330329	hsa-miR-2114	CLIP-seq
MIRT1330330	hsa-miR-214	CLIP-seq
MIRT1330331	hsa-miR-3187-5p	CLIP-seq
MIRT1330332	hsa-miR-3619-5p	CLIP-seq
MIRT1330333	hsa-miR-3622b-5p	CLIP-seq
MIRT1330334	hsa-miR-3945	CLIP-seq
MIRT1330335	hsa-miR-4253	CLIP-seq
MIRT1330336	hsa-miR-4270	CLIP-seq
MIRT1330337	hsa-miR-4291	CLIP-seq
MIRT1330338	hsa-miR-4433	CLIP-seq
MIRT1330339	hsa-miR-4441	CLIP-seq
MIRT1330340	hsa-miR-4471	CLIP-seq
MIRT1330341	hsa-miR-4514	CLIP-seq
MIRT1330342	hsa-miR-4662a-5p	CLIP-seq
MIRT1330343	hsa-miR-4690-5p	CLIP-seq
MIRT1330344	hsa-miR-4692	CLIP-seq
MIRT1330345	hsa-miR-4739	CLIP-seq
MIRT1330346	hsa-miR-4756-5p	CLIP-seq
MIRT1330347	hsa-miR-4763-3p	CLIP-seq
MIRT1330348	hsa-miR-4767	CLIP-seq
MIRT1330349	hsa-miR-510	CLIP-seq
MIRT1330350	hsa-miR-512-5p	CLIP-seq
MIRT1330351	hsa-miR-513a-5p	CLIP-seq
MIRT1330352	hsa-miR-566	CLIP-seq
MIRT1330353	hsa-miR-612	CLIP-seq
MIRT1330354	hsa-miR-663	CLIP-seq
MIRT1330355	hsa-miR-761	CLIP-seq
MIRT1330356	hsa-miR-922	CLIP-seq
MIRT1330327	hsa-miR-146b-3p	CLIP-seq
MIRT1330357	hsa-miR-24	CLIP-seq
MIRT1330358	hsa-miR-27a	CLIP-seq
MIRT1330359	hsa-miR-27b	CLIP-seq
MIRT1330360	hsa-miR-3652	CLIP-seq
MIRT1330361	hsa-miR-4252	CLIP-seq
MIRT1330362	hsa-miR-4284	CLIP-seq
MIRT1330363	hsa-miR-4430	CLIP-seq
MIRT1330338	hsa-miR-4433	CLIP-seq
MIRT1330364	hsa-miR-4466	CLIP-seq
MIRT1330340	hsa-miR-4471	CLIP-seq
MIRT1330365	hsa-miR-4486	CLIP-seq
MIRT1330366	hsa-miR-4505	CLIP-seq
MIRT1330367	hsa-miR-4649-5p	CLIP-seq
MIRT1330342	hsa-miR-4662a-5p	CLIP-seq
MIRT1330368	hsa-miR-4746-3p	CLIP-seq
MIRT1330369	hsa-miR-4793-3p	CLIP-seq
MIRT1330370	hsa-miR-508-5p	CLIP-seq
MIRT1330351	hsa-miR-513a-5p	CLIP-seq
MIRT1330371	hsa-miR-541	CLIP-seq
MIRT1330372	hsa-miR-661	CLIP-seq
MIRT1330373	hsa-miR-675	CLIP-seq
MIRT1330374	hsa-miR-766	CLIP-seq
MIRT1330327	hsa-miR-146b-3p	CLIP-seq
MIRT1330357	hsa-miR-24	CLIP-seq
MIRT1330358	hsa-miR-27a	CLIP-seq
MIRT1330359	hsa-miR-27b	CLIP-seq
MIRT2097842	hsa-miR-3613-3p	CLIP-seq
MIRT1330360	hsa-miR-3652	CLIP-seq
MIRT1330362	hsa-miR-4284	CLIP-seq
MIRT1330363	hsa-miR-4430	CLIP-seq
MIRT1330364	hsa-miR-4466	CLIP-seq
MIRT1330340	hsa-miR-4471	CLIP-seq
MIRT1330366	hsa-miR-4505	CLIP-seq
MIRT2097843	hsa-miR-4522	CLIP-seq
MIRT1330342	hsa-miR-4662a-5p	CLIP-seq
MIRT1330368	hsa-miR-4746-3p	CLIP-seq
MIRT1330351	hsa-miR-513a-5p	CLIP-seq
MIRT1330371	hsa-miR-541	CLIP-seq
MIRT1330373	hsa-miR-675	CLIP-seq
MIRT2322153	hsa-miR-1227	CLIP-seq
MIRT1330325	hsa-miR-1285	CLIP-seq
MIRT1330327	hsa-miR-146b-3p	CLIP-seq
MIRT1330328	hsa-miR-1908	CLIP-seq
MIRT1330329	hsa-miR-2114	CLIP-seq
MIRT1330357	hsa-miR-24	CLIP-seq
MIRT1330331	hsa-miR-3187-5p	CLIP-seq
MIRT1330333	hsa-miR-3622b-5p	CLIP-seq
MIRT1330360	hsa-miR-3652	CLIP-seq
MIRT1330334	hsa-miR-3945	CLIP-seq
MIRT1330361	hsa-miR-4252	CLIP-seq
MIRT1330335	hsa-miR-4253	CLIP-seq
MIRT1330362	hsa-miR-4284	CLIP-seq
MIRT1330363	hsa-miR-4430	CLIP-seq
MIRT1330338	hsa-miR-4433	CLIP-seq
MIRT1330364	hsa-miR-4466	CLIP-seq
MIRT1330340	hsa-miR-4471	CLIP-seq
MIRT1330365	hsa-miR-4486	CLIP-seq
MIRT1330366	hsa-miR-4505	CLIP-seq
MIRT1330367	hsa-miR-4649-5p	CLIP-seq
MIRT1330342	hsa-miR-4662a-5p	CLIP-seq
MIRT1330368	hsa-miR-4746-3p	CLIP-seq
MIRT1330348	hsa-miR-4767	CLIP-seq
MIRT1330369	hsa-miR-4793-3p	CLIP-seq
MIRT1330370	hsa-miR-508-5p	CLIP-seq
MIRT1330349	hsa-miR-510	CLIP-seq
MIRT1330350	hsa-miR-512-5p	CLIP-seq
MIRT1330351	hsa-miR-513a-5p	CLIP-seq
MIRT1330352	hsa-miR-566	CLIP-seq
MIRT1330353	hsa-miR-612	CLIP-seq
MIRT1330372	hsa-miR-661	CLIP-seq
MIRT1330354	hsa-miR-663	CLIP-seq
MIRT1330373	hsa-miR-675	CLIP-seq
MIRT1330374	hsa-miR-766	CLIP-seq
MIRT1330327	hsa-miR-146b-3p	CLIP-seq
MIRT1330340	hsa-miR-4471	CLIP-seq
MIRT1330342	hsa-miR-4662a-5p	CLIP-seq
MIRT1330351	hsa-miR-513a-5p	CLIP-seq
MIRT2458967	hsa-miR-128	CLIP-seq
MIRT1330325	hsa-miR-1285	CLIP-seq
MIRT1330328	hsa-miR-1908	CLIP-seq
MIRT1330331	hsa-miR-3187-5p	CLIP-seq
MIRT2097842	hsa-miR-3613-3p	CLIP-seq
MIRT1330333	hsa-miR-3622b-5p	CLIP-seq
MIRT1330334	hsa-miR-3945	CLIP-seq
MIRT1330335	hsa-miR-4253	CLIP-seq
MIRT1330338	hsa-miR-4433	CLIP-seq
MIRT2458968	hsa-miR-4684-5p	CLIP-seq
MIRT1330348	hsa-miR-4767	CLIP-seq
MIRT1330371	hsa-miR-541	CLIP-seq
MIRT2458969	hsa-miR-548c-3p	CLIP-seq
MIRT1330352	hsa-miR-566	CLIP-seq
MIRT1330353	hsa-miR-612	CLIP-seq
MIRT1330354	hsa-miR-663	CLIP-seq
MIRT2458967	hsa-miR-128	CLIP-seq
MIRT1330325	hsa-miR-1285	CLIP-seq
MIRT1330328	hsa-miR-1908	CLIP-seq
MIRT1330331	hsa-miR-3187-5p	CLIP-seq
MIRT2097842	hsa-miR-3613-3p	CLIP-seq
MIRT1330333	hsa-miR-3622b-5p	CLIP-seq
MIRT1330334	hsa-miR-3945	CLIP-seq
MIRT1330335	hsa-miR-4253	CLIP-seq
MIRT2458968	hsa-miR-4684-5p	CLIP-seq
MIRT1330348	hsa-miR-4767	CLIP-seq
MIRT2458969	hsa-miR-548c-3p	CLIP-seq
MIRT1330352	hsa-miR-566	CLIP-seq
MIRT1330353	hsa-miR-612	CLIP-seq
MIRT1330354	hsa-miR-663	CLIP-seq
MIRT2458967	hsa-miR-128	CLIP-seq
MIRT1330325	hsa-miR-1285	CLIP-seq
MIRT1330328	hsa-miR-1908	CLIP-seq
MIRT1330331	hsa-miR-3187-5p	CLIP-seq
MIRT2097842	hsa-miR-3613-3p	CLIP-seq
MIRT1330333	hsa-miR-3622b-5p	CLIP-seq
MIRT2618516	hsa-miR-371b-5p	CLIP-seq
MIRT1330334	hsa-miR-3945	CLIP-seq
MIRT1330361	hsa-miR-4252	CLIP-seq
MIRT1330335	hsa-miR-4253	CLIP-seq
MIRT1330338	hsa-miR-4433	CLIP-seq
MIRT1330365	hsa-miR-4486	CLIP-seq
MIRT2097843	hsa-miR-4522	CLIP-seq
MIRT1330367	hsa-miR-4649-5p	CLIP-seq
MIRT2458968	hsa-miR-4684-5p	CLIP-seq
MIRT1330348	hsa-miR-4767	CLIP-seq
MIRT2618517	hsa-miR-4786-5p	CLIP-seq
MIRT1330369	hsa-miR-4793-3p	CLIP-seq
MIRT2618518	hsa-miR-4793-5p	CLIP-seq
MIRT2618519	hsa-miR-4794	CLIP-seq
MIRT1330370	hsa-miR-508-5p	CLIP-seq
MIRT1330371	hsa-miR-541	CLIP-seq
MIRT2458969	hsa-miR-548c-3p	CLIP-seq
MIRT1330352	hsa-miR-566	CLIP-seq
MIRT1330353	hsa-miR-612	CLIP-seq
MIRT1330372	hsa-miR-661	CLIP-seq
MIRT1330354	hsa-miR-663	CLIP-seq
MIRT1330374	hsa-miR-766	CLIP-seq
MIRT2458967	hsa-miR-128	CLIP-seq
MIRT1330325	hsa-miR-1285	CLIP-seq
MIRT1330328	hsa-miR-1908	CLIP-seq
MIRT1330329	hsa-miR-2114	CLIP-seq
MIRT1330331	hsa-miR-3187-5p	CLIP-seq
MIRT2097842	hsa-miR-3613-3p	CLIP-seq
MIRT1330333	hsa-miR-3622b-5p	CLIP-seq
MIRT2618516	hsa-miR-371b-5p	CLIP-seq
MIRT1330334	hsa-miR-3945	CLIP-seq
MIRT1330361	hsa-miR-4252	CLIP-seq
MIRT1330335	hsa-miR-4253	CLIP-seq
MIRT1330338	hsa-miR-4433	CLIP-seq
MIRT1330365	hsa-miR-4486	CLIP-seq
MIRT2097843	hsa-miR-4522	CLIP-seq
MIRT1330367	hsa-miR-4649-5p	CLIP-seq
MIRT2458968	hsa-miR-4684-5p	CLIP-seq
MIRT1330348	hsa-miR-4767	CLIP-seq
MIRT2618517	hsa-miR-4786-5p	CLIP-seq
MIRT1330369	hsa-miR-4793-3p	CLIP-seq
MIRT2618518	hsa-miR-4793-5p	CLIP-seq
MIRT2618519	hsa-miR-4794	CLIP-seq
MIRT1330370	hsa-miR-508-5p	CLIP-seq
MIRT1330371	hsa-miR-541	CLIP-seq
MIRT2458969	hsa-miR-548c-3p	CLIP-seq
MIRT1330352	hsa-miR-566	CLIP-seq
MIRT1330353	hsa-miR-612	CLIP-seq
MIRT1330372	hsa-miR-661	CLIP-seq
MIRT1330354	hsa-miR-663	CLIP-seq
MIRT1330374	hsa-miR-766	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000380	Process	Alternative mRNA splicing, via spliceosome	IEA
GO:0000380	Process	Alternative mRNA splicing, via spliceosome	ISS
GO:0005515	Function	Protein binding	IPI	25416956, 27107012, 28514442, 29892012, 31515488, 32296183, 32814053, 33961781
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IEA
GO:0005681	Component	Spliceosomal complex	IEA
GO:0006397	Process	MRNA processing	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0008380	Process	RNA splicing	IBA
GO:0008380	Process	RNA splicing	IEA
GO:0008380	Process	RNA splicing	IEA
GO:0016607	Component	Nuclear speck	IEA
GO:0016607	Component	Nuclear speck	ISS
GO:0019899	Function	Enzyme binding	IPI	23382074
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 608095
• HGNC: 23136
• e!Ensembl: ENSG00000163156

Interactions View interactions

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Orofaciodigital syndrome 19	Pathogenic	rs2525218255, rs2525218553	RCV002294745 RCV002294747	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
OROFACIODIGITAL SYNDROME XIX	—	Disgenet, HPO Disgenet, HPO	★★☆☆☆ Found in Text Mining + Unknown/Other Associations