Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	7862
Gene name	Bromodomain and PHD finger containing 1
Gene symbol	BRPF1
Synonyms (NCBI Gene)	BR140IDDDFP
Chromosome	3
Chromosome location	3p25.3
Summary	This gene encodes a bromodomain, PHD finger and chromo/Tudor-related Pro-Trp-Trp-Pro (PWWP) domain containing protein. The encoded protein is a component of the MOZ/MORF histone acetyltransferase complexes which function as a transcriptional regulators. T

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SNP ID	Visualize variation	Clinical significance	Consequence
rs762904815	C>-,CC,CCC	Pathogenic	Intron variant, non coding transcript variant, frameshift variant, coding sequence variant
rs886041090	TG>-	Pathogenic	Frameshift variant, non coding transcript variant, coding sequence variant
rs1057519509	C>T	Pathogenic	Missense variant, non coding transcript variant, coding sequence variant
rs1057519510	C>T	Pathogenic	Stop gained, non coding transcript variant, coding sequence variant
rs1057519511	AG>-	Pathogenic	Frameshift variant, non coding transcript variant, coding sequence variant
rs1057519512	C>T	Pathogenic	Stop gained, non coding transcript variant, coding sequence variant
rs1057519513	C>T	Pathogenic	Stop gained, non coding transcript variant, coding sequence variant
rs1057519514	C>G	Pathogenic	Stop gained, non coding transcript variant, coding sequence variant
rs1057519515	T>C	Pathogenic	Missense variant, non coding transcript variant, coding sequence variant
rs1057519516	T>-	Pathogenic	Frameshift variant, non coding transcript variant, coding sequence variant
rs1057519517	->A	Pathogenic	Stop gained, non coding transcript variant, coding sequence variant
rs1553693702	G>A	Pathogenic	Missense variant, non coding transcript variant, initiator codon variant
rs1553693712	TT>-	Pathogenic	Frameshift variant, non coding transcript variant, coding sequence variant
rs1553693863	C>T	Pathogenic	Non coding transcript variant, stop gained, coding sequence variant
rs1553695017	C>T	Pathogenic	Non coding transcript variant, stop gained, coding sequence variant
rs1553695038	G>A	Likely-pathogenic	Non coding transcript variant, missense variant, coding sequence variant
rs1553695222	C>G	Pathogenic	Non coding transcript variant, stop gained, coding sequence variant
rs1553695254	A>-	Pathogenic	Frameshift variant, non coding transcript variant, coding sequence variant
rs1553696275	GA>-	Pathogenic	Frameshift variant, non coding transcript variant, coding sequence variant
rs1553697341	CTT>-	Likely-pathogenic	Non coding transcript variant, inframe deletion, coding sequence variant
rs1559662068	AG>T	Likely-pathogenic	Non coding transcript variant, frameshift variant, coding sequence variant
rs1559662077	C>T	Likely-pathogenic	Non coding transcript variant, stop gained, coding sequence variant
rs1575147387	GGACACCCCTGAT>AGGTAGAGGTG	Pathogenic	Non coding transcript variant, frameshift variant, coding sequence variant
rs1575155995	AG>-	Pathogenic	Non coding transcript variant, frameshift variant, coding sequence variant
rs1575164369	ATAG>-	Pathogenic	Non coding transcript variant, frameshift variant, coding sequence variant

160

Show/Hide all (160)

miRTarBase ID	miRNA	Experiments	Reference
MIRT052041	hsa-let-7b-5p	CLASH	23622248
MIRT050786	hsa-miR-17-3p	CLASH	23622248
MIRT047074	hsa-miR-183-5p	CLASH	23622248
MIRT043564	hsa-miR-331-3p	CLASH	23622248
MIRT480714	hsa-miR-3927-3p	PAR-CLIP	23592263
MIRT480713	hsa-miR-6831-5p	PAR-CLIP	23592263
MIRT480712	hsa-miR-4468	PAR-CLIP	23592263
MIRT480711	hsa-miR-6134	PAR-CLIP	23592263
MIRT480710	hsa-miR-6735-3p	PAR-CLIP	23592263
MIRT480708	hsa-miR-5187-5p	PAR-CLIP	23592263
MIRT480709	hsa-miR-4451	PAR-CLIP	23592263
MIRT480707	hsa-miR-541-3p	PAR-CLIP	23592263
MIRT480706	hsa-miR-654-5p	PAR-CLIP	23592263
MIRT480705	hsa-miR-6769a-5p	PAR-CLIP	23592263
MIRT480703	hsa-miR-6769b-5p	PAR-CLIP	23592263
MIRT480704	hsa-miR-4654	PAR-CLIP	23592263
MIRT480702	hsa-miR-4769-5p	PAR-CLIP	23592263
MIRT480701	hsa-miR-6728-5p	PAR-CLIP	23592263
MIRT480700	hsa-miR-488-3p	PAR-CLIP	23592263
MIRT480699	hsa-miR-6715a-3p	PAR-CLIP	23592263
MIRT480698	hsa-miR-5681a	PAR-CLIP	23592263
MIRT480697	hsa-miR-6730-5p	PAR-CLIP	23592263
MIRT480696	hsa-miR-625-5p	PAR-CLIP	23592263
MIRT480695	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT480694	hsa-miR-5698	PAR-CLIP	23592263
MIRT480693	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT480692	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT480690	hsa-miR-4525	PAR-CLIP	23592263
MIRT480691	hsa-miR-5010-5p	PAR-CLIP	23592263
MIRT480689	hsa-miR-92a-2-5p	PAR-CLIP	23592263
MIRT480688	hsa-miR-4447	PAR-CLIP	23592263
MIRT480687	hsa-miR-4472	PAR-CLIP	23592263
MIRT480686	hsa-miR-1275	PAR-CLIP	23592263
MIRT480685	hsa-miR-4665-5p	PAR-CLIP	23592263
MIRT480684	hsa-miR-510-3p	PAR-CLIP	23592263
MIRT480683	hsa-miR-6782-5p	PAR-CLIP	23592263
MIRT480714	hsa-miR-3927-3p	PAR-CLIP	23592263
MIRT480713	hsa-miR-6831-5p	PAR-CLIP	23592263
MIRT480712	hsa-miR-4468	PAR-CLIP	23592263
MIRT480711	hsa-miR-6134	PAR-CLIP	23592263
MIRT480710	hsa-miR-6735-3p	PAR-CLIP	23592263
MIRT480708	hsa-miR-5187-5p	PAR-CLIP	23592263
MIRT480709	hsa-miR-4451	PAR-CLIP	23592263
MIRT480707	hsa-miR-541-3p	PAR-CLIP	23592263
MIRT480706	hsa-miR-654-5p	PAR-CLIP	23592263
MIRT480705	hsa-miR-6769a-5p	PAR-CLIP	23592263
MIRT480703	hsa-miR-6769b-5p	PAR-CLIP	23592263
MIRT480704	hsa-miR-4654	PAR-CLIP	23592263
MIRT480702	hsa-miR-4769-5p	PAR-CLIP	23592263
MIRT480701	hsa-miR-6728-5p	PAR-CLIP	23592263
MIRT480700	hsa-miR-488-3p	PAR-CLIP	23592263
MIRT480699	hsa-miR-6715a-3p	PAR-CLIP	23592263
MIRT480698	hsa-miR-5681a	PAR-CLIP	23592263
MIRT480697	hsa-miR-6730-5p	PAR-CLIP	23592263
MIRT480696	hsa-miR-625-5p	PAR-CLIP	23592263
MIRT480695	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT480694	hsa-miR-5698	PAR-CLIP	23592263
MIRT480693	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT480692	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT480690	hsa-miR-4525	PAR-CLIP	23592263
MIRT480691	hsa-miR-5010-5p	PAR-CLIP	23592263
MIRT480689	hsa-miR-92a-2-5p	PAR-CLIP	23592263
MIRT480688	hsa-miR-4447	PAR-CLIP	23592263
MIRT480687	hsa-miR-4472	PAR-CLIP	23592263
MIRT480686	hsa-miR-1275	PAR-CLIP	23592263
MIRT480685	hsa-miR-4665-5p	PAR-CLIP	23592263
MIRT480684	hsa-miR-510-3p	PAR-CLIP	23592263
MIRT480683	hsa-miR-6782-5p	PAR-CLIP	23592263
MIRT825331	hsa-miR-101	CLIP-seq
MIRT825332	hsa-miR-144	CLIP-seq
MIRT825333	hsa-miR-1909	CLIP-seq
MIRT825334	hsa-miR-214	CLIP-seq
MIRT825335	hsa-miR-3136-3p	CLIP-seq
MIRT825336	hsa-miR-328	CLIP-seq
MIRT825337	hsa-miR-3619-5p	CLIP-seq
MIRT825338	hsa-miR-371-3p	CLIP-seq
MIRT825339	hsa-miR-371b-3p	CLIP-seq
MIRT825340	hsa-miR-4419a	CLIP-seq
MIRT825341	hsa-miR-4510	CLIP-seq
MIRT825342	hsa-miR-4699-3p	CLIP-seq
MIRT825343	hsa-miR-4728-5p	CLIP-seq
MIRT825344	hsa-miR-515-3p	CLIP-seq
MIRT825345	hsa-miR-519e	CLIP-seq
MIRT825346	hsa-miR-582-5p	CLIP-seq
MIRT825347	hsa-miR-761	CLIP-seq
MIRT825331	hsa-miR-101	CLIP-seq
MIRT825332	hsa-miR-144	CLIP-seq
MIRT825333	hsa-miR-1909	CLIP-seq
MIRT825334	hsa-miR-214	CLIP-seq
MIRT825348	hsa-miR-3153	CLIP-seq
MIRT825349	hsa-miR-3154	CLIP-seq
MIRT825337	hsa-miR-3619-5p	CLIP-seq
MIRT825350	hsa-miR-4311	CLIP-seq
MIRT825351	hsa-miR-4522	CLIP-seq
MIRT825352	hsa-miR-4634	CLIP-seq
MIRT825353	hsa-miR-4668-5p	CLIP-seq
MIRT825342	hsa-miR-4699-3p	CLIP-seq
MIRT825343	hsa-miR-4728-5p	CLIP-seq
MIRT825354	hsa-miR-520d-5p	CLIP-seq
MIRT825355	hsa-miR-524-5p	CLIP-seq
MIRT825356	hsa-miR-580	CLIP-seq
MIRT825347	hsa-miR-761	CLIP-seq
MIRT825357	hsa-miR-935	CLIP-seq
MIRT1943890	hsa-miR-1587	CLIP-seq
MIRT1943891	hsa-miR-185	CLIP-seq
MIRT825333	hsa-miR-1909	CLIP-seq
MIRT1943892	hsa-miR-203	CLIP-seq
MIRT825334	hsa-miR-214	CLIP-seq
MIRT1943893	hsa-miR-224	CLIP-seq
MIRT1943894	hsa-miR-3121-5p	CLIP-seq
MIRT1943895	hsa-miR-3147	CLIP-seq
MIRT1943896	hsa-miR-3150b-3p	CLIP-seq
MIRT825348	hsa-miR-3153	CLIP-seq
MIRT825337	hsa-miR-3619-5p	CLIP-seq
MIRT825338	hsa-miR-371-3p	CLIP-seq
MIRT825339	hsa-miR-371b-3p	CLIP-seq
MIRT1943897	hsa-miR-4306	CLIP-seq
MIRT825340	hsa-miR-4419a	CLIP-seq
MIRT1943898	hsa-miR-4436a	CLIP-seq
MIRT1943899	hsa-miR-4492	CLIP-seq
MIRT1943900	hsa-miR-4498	CLIP-seq
MIRT825341	hsa-miR-4510	CLIP-seq
MIRT1943901	hsa-miR-4644	CLIP-seq
MIRT1943902	hsa-miR-4656	CLIP-seq
MIRT1943903	hsa-miR-4659a-3p	CLIP-seq
MIRT1943904	hsa-miR-4659b-3p	CLIP-seq
MIRT825353	hsa-miR-4668-5p	CLIP-seq
MIRT1943905	hsa-miR-4674	CLIP-seq
MIRT1943906	hsa-miR-4675	CLIP-seq
MIRT825342	hsa-miR-4699-3p	CLIP-seq
MIRT825343	hsa-miR-4728-5p	CLIP-seq
MIRT1943907	hsa-miR-4741	CLIP-seq
MIRT1943908	hsa-miR-4784	CLIP-seq
MIRT1943909	hsa-miR-488	CLIP-seq
MIRT1943910	hsa-miR-508-5p	CLIP-seq
MIRT1943911	hsa-miR-513a-5p	CLIP-seq
MIRT825344	hsa-miR-515-3p	CLIP-seq
MIRT825345	hsa-miR-519e	CLIP-seq
MIRT1943912	hsa-miR-625	CLIP-seq
MIRT1943913	hsa-miR-665	CLIP-seq
MIRT825347	hsa-miR-761	CLIP-seq
MIRT1943914	hsa-miR-762	CLIP-seq
MIRT1943915	hsa-miR-765	CLIP-seq
MIRT2182579	hsa-miR-1236	CLIP-seq
MIRT2182580	hsa-miR-3652	CLIP-seq
MIRT2182581	hsa-miR-4430	CLIP-seq
MIRT1943898	hsa-miR-4436a	CLIP-seq
MIRT2182582	hsa-miR-4520a-3p	CLIP-seq
MIRT2182583	hsa-miR-4638-3p	CLIP-seq
MIRT2182584	hsa-miR-4645-5p	CLIP-seq
MIRT2182585	hsa-miR-4673	CLIP-seq
MIRT2182586	hsa-miR-4749-3p	CLIP-seq
MIRT1943910	hsa-miR-508-5p	CLIP-seq
MIRT1943913	hsa-miR-665	CLIP-seq
MIRT2486290	hsa-miR-148a	CLIP-seq
MIRT2486291	hsa-miR-148b	CLIP-seq
MIRT2486292	hsa-miR-152	CLIP-seq
MIRT2486293	hsa-miR-2467-3p	CLIP-seq
MIRT2486294	hsa-miR-3678-3p	CLIP-seq
MIRT2486295	hsa-miR-4697-3p	CLIP-seq

Show/Hide all (27)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000123	Component	Histone acetyltransferase complex	IDA	24065767
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	25281266, 32296183
GO:0005634	Component	Nucleus	IDA	18794358, 24065767, 25593309, 27939640
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005694	Component	Chromosome	IEA
GO:0005737	Component	Cytoplasm	IDA	27939640
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005886	Component	Plasma membrane	IDA
GO:0006325	Process	Chromatin organization	IEA
GO:0006338	Process	Chromatin remodeling	IMP	27939640
GO:0006355	Process	Regulation of DNA-templated transcription	IDA	18794358
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0010698	Function	Acetyltransferase activator activity	IDA	27939640
GO:0043995	Function	Histone H4K5 acetyltransferase activity	IDA	16387653
GO:0043996	Function	Histone H4K8 acetyltransferase activity	IDA	16387653
GO:0043997	Function	Histone H4K12 acetyltransferase activity	IDA	16387653
GO:0045893	Process	Positive regulation of DNA-templated transcription	IDA	18794358
GO:0046872	Function	Metal ion binding	IEA
GO:0050793	Process	Regulation of developmental process	NAS	16387653
GO:0070776	Component	MOZ/MORF histone acetyltransferase complex	IBA
GO:0070776	Component	MOZ/MORF histone acetyltransferase complex	IDA	16387653, 18794358, 27939640
GO:0070776	Component	MOZ/MORF histone acetyltransferase complex	IEA
GO:1903706	Process	Regulation of hemopoiesis	NAS	16387653

MIM	HGNC	e!Ensembl
602410	14255	ENSG00000156983

P55201

Protein name

Peregrin (Bromodomain and PHD finger-containing protein 1) (Protein Br140)

Protein function

Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, which have a histone H3 acetyltransferase activity (PubMed:16387653, PubMed:24065767, PubMed:27939640). Plays a key role in HBO1 comp

PDB

2D9E , 2RS9 , 2X35 , 2X4W , 2X4X , 2X4Y , 3L42 , 3MO8 , 4LC2 , 4QYD , 4QYL , 4UYE , 5C6S , 5C7N , 5C85 , 5C87 , 5C89 , 5D7X , 5DY7 , 5DYA , 5DYC , 5E3D , 5E3G , 5EM3 , 5EPR , 5EPS , 5EQ1 , 5ERC , 5ETB , 5ETD , 5EV9 , 5EVA , 5EWC , 5EWD , 5EWH , 5EWV , 5EWW , 5FFV , 5FFW , 5FFY , 5FG4 , 5FG5 , 5G4R , 5G4S , 5MWG , 5MWH , 5MWZ , 5MYG , 5O4S , 5O4T , 5O55

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF10513	EPL1	106 → 255	Enhancer of polycomb-like	Family
PF13831	PHD_2	287 → 321		Family
PF13832	zf-HC5HC2H_2	328 → 447		Domain
PF00439	Bromodomain	637 → 720	Bromodomain	Domain
PF00855	PWWP	1083 → 1200	PWWP domain	Domain

Tissue specificity

TISSUE SPECIFICITY: High levels in testis. {ECO:0000269|PubMed:7906940}.

Sequence

MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK
HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS
EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV
YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI
PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV
HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV
CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY
MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS
EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL
HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER
ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS
EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVR
LREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLLENQKHL
PVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGPS
SRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPK
TAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSSDSDSDK
STEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASDRTSTTP
SKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGWLSEDED
SPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEARE
HLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRS
KVQGEQSSETSDSD

Sequence length

1214

Interactions

View interactions

	Reactome
			HATs acetylate histones Regulation of TP53 Activity through Acetylation

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Causal Diseases (6)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
BRPF1-related disorder	Pathogenic; Likely pathogenic	rs2125500187, rs2471511294, rs2471497955, rs2471469955	RCV004746505 RCV003394451 RCV003393033 RCV003397781	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Global developmental delay	Pathogenic	rs1575155995	RCV001526572	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Intellectual developmental disorder with dysmorphic facies and ptosis	Likely pathogenic; Pathogenic	rs2125489641, rs1367505804, rs2125511510, rs2125501418, rs2125503212, rs2125515297, rs2125500625, rs2125500187, rs2125500524, rs2125507908, rs2125514693, rs2125500407, rs2125504267, rs2471501529, rs759029777 View all (30 more)	RCV001374610 RCV001788504 RCV001784054 RCV001808301 RCV001808849 View all (40 more)	★★★★★ ★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Intellectual disability	Pathogenic	rs886041090, rs2077100499	RCV000258899 RCV001249495	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Neurodevelopmental disorder	Likely pathogenic; Pathogenic	rs2125507991, rs1057519511	RCV001780058 RCV000505254	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Sudden unexplained death in childhood	Pathogenic	rs1575155995	RCV001788390	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Show/Hide Unknown Diseases (7)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Autistic behavior	Uncertain significance	ClinVar Disgenet	★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
DEVELOPMENTAL DISABILITIES	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Developmental disorder	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Neurodevelopmental delay	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEURODEVELOPMENTAL DISORDERS	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATIC NEOPLASMS	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

BRPF1 (bromodomain and PHD finger containing 1)