SLC30A4 (solute carrier family 30 member 4)

Gene

• Entrez ID: 7782
• Gene name: Solute carrier family 30 member 4
• Gene symbol: SLC30A4
• Synonyms (NCBI Gene): ZNT4, znT-4
• Chromosome: 15
• Chromosome location: 15q21.1|15q21.1
• Summary: Zinc is the second most abundant trace metal in the human body. It is an essential element, serving both a structural role, as in the formation of zinc fingers in DNA-binding proteins, and a catalytic role in metalloenzymes, such as pancreatic carboxypept

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT021423	hsa-miR-9-5p	Microarray	17612493
MIRT521043	hsa-miR-3120-3p	HITS-CLIP	21572407
MIRT521042	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT521040	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT521035	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT521035	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT521042	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT521040	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT521039	hsa-miR-7641	HITS-CLIP	23313552
MIRT521034	hsa-miR-8058	HITS-CLIP	23313552
MIRT653621	hsa-miR-548aa	HITS-CLIP	23824327
MIRT653620	hsa-miR-548ap-3p	HITS-CLIP	23824327
MIRT653619	hsa-miR-548t-3p	HITS-CLIP	23824327
MIRT653618	hsa-miR-497-3p	HITS-CLIP	23824327
MIRT653616	hsa-miR-8485	HITS-CLIP	23824327
MIRT653617	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT641528	hsa-miR-186-5p	HITS-CLIP	23824327
MIRT641527	hsa-miR-302a-5p	HITS-CLIP	23824327
MIRT641526	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT641525	hsa-miR-1305	HITS-CLIP	23824327
MIRT641524	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT521042	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT521040	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT521039	hsa-miR-7641	HITS-CLIP	23824327
MIRT521035	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521034	hsa-miR-8058	HITS-CLIP	23824327
MIRT521043	hsa-miR-3120-3p	PAR-CLIP	23446348
MIRT521042	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT521041	hsa-miR-4684-3p	PAR-CLIP	23446348
MIRT521040	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT521039	hsa-miR-7641	PAR-CLIP	23446348
MIRT521038	hsa-miR-548aw	PAR-CLIP	23446348
MIRT521037	hsa-miR-518a-5p	PAR-CLIP	23446348
MIRT521036	hsa-miR-527	PAR-CLIP	23446348
MIRT521035	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT521034	hsa-miR-8058	PAR-CLIP	23446348
MIRT521043	hsa-miR-3120-3p	HITS-CLIP	21572407
MIRT521042	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT521040	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT521035	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT521035	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT521042	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT521040	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT521039	hsa-miR-7641	HITS-CLIP	23313552
MIRT521034	hsa-miR-8058	HITS-CLIP	23313552
MIRT653621	hsa-miR-548aa	HITS-CLIP	23824327
MIRT653620	hsa-miR-548ap-3p	HITS-CLIP	23824327
MIRT653619	hsa-miR-548t-3p	HITS-CLIP	23824327
MIRT653618	hsa-miR-497-3p	HITS-CLIP	23824327
MIRT653616	hsa-miR-8485	HITS-CLIP	23824327
MIRT653617	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT641528	hsa-miR-186-5p	HITS-CLIP	23824327
MIRT641527	hsa-miR-302a-5p	HITS-CLIP	23824327
MIRT641526	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT641525	hsa-miR-1305	HITS-CLIP	23824327
MIRT641524	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT521042	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT521040	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT521039	hsa-miR-7641	HITS-CLIP	23824327
MIRT521035	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT521034	hsa-miR-8058	HITS-CLIP	23824327
MIRT521043	hsa-miR-3120-3p	PAR-CLIP	23446348
MIRT521042	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT521041	hsa-miR-4684-3p	PAR-CLIP	23446348
MIRT521040	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT521039	hsa-miR-7641	PAR-CLIP	23446348
MIRT521038	hsa-miR-548aw	PAR-CLIP	23446348
MIRT521037	hsa-miR-518a-5p	PAR-CLIP	23446348
MIRT521036	hsa-miR-527	PAR-CLIP	23446348
MIRT521035	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT521034	hsa-miR-8058	PAR-CLIP	23446348
MIRT1359156	hsa-miR-1231	CLIP-seq
MIRT1359157	hsa-miR-1827	CLIP-seq
MIRT1359158	hsa-miR-208a	CLIP-seq
MIRT1359159	hsa-miR-208b	CLIP-seq
MIRT1359160	hsa-miR-2115	CLIP-seq
MIRT1359161	hsa-miR-2467-3p	CLIP-seq
MIRT1359162	hsa-miR-298	CLIP-seq
MIRT1359163	hsa-miR-3064-3p	CLIP-seq
MIRT1359164	hsa-miR-3176	CLIP-seq
MIRT1359165	hsa-miR-3180-5p	CLIP-seq
MIRT1359166	hsa-miR-3202	CLIP-seq
MIRT1359167	hsa-miR-338-3p	CLIP-seq
MIRT1359168	hsa-miR-34b	CLIP-seq
MIRT1359169	hsa-miR-3612	CLIP-seq
MIRT1359170	hsa-miR-3614-5p	CLIP-seq
MIRT1359171	hsa-miR-3617	CLIP-seq
MIRT1359172	hsa-miR-3646	CLIP-seq
MIRT1359173	hsa-miR-3658	CLIP-seq
MIRT1359174	hsa-miR-3664-5p	CLIP-seq
MIRT1359175	hsa-miR-3714	CLIP-seq
MIRT1359176	hsa-miR-3922-3p	CLIP-seq
MIRT1359177	hsa-miR-4257	CLIP-seq
MIRT1359178	hsa-miR-4452	CLIP-seq
MIRT1359179	hsa-miR-4459	CLIP-seq
MIRT1359180	hsa-miR-4468	CLIP-seq
MIRT1359181	hsa-miR-4493	CLIP-seq
MIRT1359182	hsa-miR-4499	CLIP-seq
MIRT1359183	hsa-miR-4505	CLIP-seq
MIRT1359184	hsa-miR-452	CLIP-seq
MIRT1359185	hsa-miR-4528	CLIP-seq
MIRT1359186	hsa-miR-4530	CLIP-seq
MIRT1359187	hsa-miR-4533	CLIP-seq
MIRT1359188	hsa-miR-4676-3p	CLIP-seq
MIRT1359189	hsa-miR-4695-5p	CLIP-seq
MIRT1359190	hsa-miR-4711-3p	CLIP-seq
MIRT1359191	hsa-miR-4714-5p	CLIP-seq
MIRT1359192	hsa-miR-4727-5p	CLIP-seq
MIRT1359193	hsa-miR-4731-5p	CLIP-seq
MIRT1359194	hsa-miR-4753-5p	CLIP-seq
MIRT1359195	hsa-miR-4769-3p	CLIP-seq
MIRT1359196	hsa-miR-486-3p	CLIP-seq
MIRT1359197	hsa-miR-499-5p	CLIP-seq
MIRT1359198	hsa-miR-516a-3p	CLIP-seq
MIRT1359199	hsa-miR-526b	CLIP-seq
MIRT1359200	hsa-miR-569	CLIP-seq
MIRT1359201	hsa-miR-582-5p	CLIP-seq
MIRT1359202	hsa-miR-617	CLIP-seq
MIRT1359203	hsa-miR-641	CLIP-seq
MIRT1359204	hsa-miR-650	CLIP-seq
MIRT1359205	hsa-miR-665	CLIP-seq
MIRT1359206	hsa-miR-889	CLIP-seq
MIRT1359207	hsa-miR-892a	CLIP-seq
MIRT1359208	hsa-miR-892b	CLIP-seq
MIRT1553759	hsa-miR-3622a-3p	CLIP-seq
MIRT1553760	hsa-miR-3622b-3p	CLIP-seq
MIRT1359175	hsa-miR-3714	CLIP-seq
MIRT1553761	hsa-miR-3937	CLIP-seq
MIRT1359181	hsa-miR-4493	CLIP-seq
MIRT1553762	hsa-miR-4722-5p	CLIP-seq
MIRT1359194	hsa-miR-4753-5p	CLIP-seq
MIRT1553763	hsa-miR-544b	CLIP-seq
MIRT1553764	hsa-miR-940	CLIP-seq
MIRT1359157	hsa-miR-1827	CLIP-seq
MIRT2106347	hsa-miR-2114	CLIP-seq
MIRT1359161	hsa-miR-2467-3p	CLIP-seq
MIRT1359162	hsa-miR-298	CLIP-seq
MIRT1359168	hsa-miR-34b	CLIP-seq
MIRT1359169	hsa-miR-3612	CLIP-seq
MIRT1359170	hsa-miR-3614-5p	CLIP-seq
MIRT2106348	hsa-miR-3672	CLIP-seq
MIRT2106349	hsa-miR-3689a-3p	CLIP-seq
MIRT2106350	hsa-miR-3689c	CLIP-seq
MIRT2106351	hsa-miR-3929	CLIP-seq
MIRT1359177	hsa-miR-4257	CLIP-seq
MIRT2106352	hsa-miR-4259	CLIP-seq
MIRT2106353	hsa-miR-4419b	CLIP-seq
MIRT2106354	hsa-miR-4425	CLIP-seq
MIRT2106355	hsa-miR-4433	CLIP-seq
MIRT2106356	hsa-miR-4455	CLIP-seq
MIRT1359179	hsa-miR-4459	CLIP-seq
MIRT1359180	hsa-miR-4468	CLIP-seq
MIRT2106357	hsa-miR-4478	CLIP-seq
MIRT2106358	hsa-miR-4649-3p	CLIP-seq
MIRT1359189	hsa-miR-4695-5p	CLIP-seq
MIRT1359190	hsa-miR-4711-3p	CLIP-seq
MIRT2106359	hsa-miR-4715-5p	CLIP-seq
MIRT2106360	hsa-miR-4728-5p	CLIP-seq
MIRT2106361	hsa-miR-4729	CLIP-seq
MIRT2106362	hsa-miR-4797-5p	CLIP-seq
MIRT2106363	hsa-miR-485-5p	CLIP-seq
MIRT2106364	hsa-miR-513c	CLIP-seq
MIRT2106365	hsa-miR-514b-5p	CLIP-seq
MIRT1359201	hsa-miR-582-5p	CLIP-seq
MIRT1359204	hsa-miR-650	CLIP-seq
MIRT1359205	hsa-miR-665	CLIP-seq
MIRT2106366	hsa-miR-759	CLIP-seq
MIRT1359207	hsa-miR-892a	CLIP-seq
MIRT2330639	hsa-miR-1184	CLIP-seq
MIRT2330640	hsa-miR-1208	CLIP-seq
MIRT2330641	hsa-miR-1267	CLIP-seq
MIRT2330642	hsa-miR-130a	CLIP-seq
MIRT2330643	hsa-miR-130b	CLIP-seq
MIRT2330644	hsa-miR-148a	CLIP-seq
MIRT2330645	hsa-miR-148b	CLIP-seq
MIRT2330646	hsa-miR-152	CLIP-seq
MIRT1359157	hsa-miR-1827	CLIP-seq
MIRT2330647	hsa-miR-1972	CLIP-seq
MIRT2330648	hsa-miR-24	CLIP-seq
MIRT1359161	hsa-miR-2467-3p	CLIP-seq
MIRT1359162	hsa-miR-298	CLIP-seq
MIRT2330649	hsa-miR-301a	CLIP-seq
MIRT2330650	hsa-miR-301b	CLIP-seq
MIRT2330651	hsa-miR-30a	CLIP-seq
MIRT2330652	hsa-miR-30b	CLIP-seq
MIRT2330653	hsa-miR-30c	CLIP-seq
MIRT2330654	hsa-miR-30d	CLIP-seq
MIRT2330655	hsa-miR-30e	CLIP-seq
MIRT2330656	hsa-miR-3122	CLIP-seq
MIRT2330657	hsa-miR-3138	CLIP-seq
MIRT2330658	hsa-miR-3145-5p	CLIP-seq
MIRT2330659	hsa-miR-3153	CLIP-seq
MIRT2330660	hsa-miR-3155	CLIP-seq
MIRT2330661	hsa-miR-3155b	CLIP-seq
MIRT1359166	hsa-miR-3202	CLIP-seq
MIRT1359168	hsa-miR-34b	CLIP-seq
MIRT2330662	hsa-miR-3607-3p	CLIP-seq
MIRT1359169	hsa-miR-3612	CLIP-seq
MIRT1359170	hsa-miR-3614-5p	CLIP-seq
MIRT1553759	hsa-miR-3622a-3p	CLIP-seq
MIRT1553760	hsa-miR-3622b-3p	CLIP-seq
MIRT2330663	hsa-miR-3650	CLIP-seq
MIRT2330664	hsa-miR-3666	CLIP-seq
MIRT2330665	hsa-miR-3686	CLIP-seq
MIRT2106349	hsa-miR-3689a-3p	CLIP-seq
MIRT2106350	hsa-miR-3689c	CLIP-seq
MIRT1359175	hsa-miR-3714	CLIP-seq
MIRT2330666	hsa-miR-3911	CLIP-seq
MIRT2330667	hsa-miR-3913-5p	CLIP-seq
MIRT2106351	hsa-miR-3929	CLIP-seq
MIRT1553761	hsa-miR-3937	CLIP-seq
MIRT1359177	hsa-miR-4257	CLIP-seq
MIRT2106352	hsa-miR-4259	CLIP-seq
MIRT2330668	hsa-miR-4261	CLIP-seq
MIRT2330669	hsa-miR-4284	CLIP-seq
MIRT2330670	hsa-miR-4295	CLIP-seq
MIRT2330671	hsa-miR-4418	CLIP-seq
MIRT2106353	hsa-miR-4419b	CLIP-seq
MIRT2106354	hsa-miR-4425	CLIP-seq
MIRT2106355	hsa-miR-4433	CLIP-seq
MIRT1359179	hsa-miR-4459	CLIP-seq
MIRT2330672	hsa-miR-4475	CLIP-seq
MIRT2106357	hsa-miR-4478	CLIP-seq
MIRT1359181	hsa-miR-4493	CLIP-seq
MIRT1359187	hsa-miR-4533	CLIP-seq
MIRT2330673	hsa-miR-454	CLIP-seq
MIRT2106358	hsa-miR-4649-3p	CLIP-seq
MIRT1359189	hsa-miR-4695-5p	CLIP-seq
MIRT2330674	hsa-miR-4714-3p	CLIP-seq
MIRT2106360	hsa-miR-4728-5p	CLIP-seq
MIRT2106361	hsa-miR-4729	CLIP-seq
MIRT1359194	hsa-miR-4753-5p	CLIP-seq
MIRT2330675	hsa-miR-4768-3p	CLIP-seq
MIRT2330676	hsa-miR-4778-5p	CLIP-seq
MIRT2330677	hsa-miR-4800-5p	CLIP-seq
MIRT2330678	hsa-miR-484	CLIP-seq
MIRT2106363	hsa-miR-485-5p	CLIP-seq
MIRT2330679	hsa-miR-494	CLIP-seq
MIRT2330680	hsa-miR-509-3-5p	CLIP-seq
MIRT2330681	hsa-miR-509-5p	CLIP-seq
MIRT2330682	hsa-miR-510	CLIP-seq
MIRT2330683	hsa-miR-512-5p	CLIP-seq
MIRT1553763	hsa-miR-544b	CLIP-seq
MIRT1359204	hsa-miR-650	CLIP-seq
MIRT2330684	hsa-miR-653	CLIP-seq
MIRT1359205	hsa-miR-665	CLIP-seq
MIRT2330685	hsa-miR-668	CLIP-seq
MIRT1553764	hsa-miR-940	CLIP-seq
MIRT2330639	hsa-miR-1184	CLIP-seq
MIRT2394717	hsa-miR-1343	CLIP-seq
MIRT2394718	hsa-miR-378g	CLIP-seq
MIRT2330671	hsa-miR-4418	CLIP-seq
MIRT2394719	hsa-miR-4422	CLIP-seq
MIRT2394720	hsa-miR-4438	CLIP-seq
MIRT2330674	hsa-miR-4714-3p	CLIP-seq
MIRT2330680	hsa-miR-509-3-5p	CLIP-seq
MIRT2394721	hsa-miR-5095	CLIP-seq
MIRT2330681	hsa-miR-509-5p	CLIP-seq
MIRT1553764	hsa-miR-940	CLIP-seq
MIRT2459671	hsa-miR-105	CLIP-seq
MIRT2459672	hsa-miR-3152-5p	CLIP-seq
MIRT1359166	hsa-miR-3202	CLIP-seq
MIRT1359181	hsa-miR-4493	CLIP-seq
MIRT1359187	hsa-miR-4533	CLIP-seq
MIRT2459673	hsa-miR-4663	CLIP-seq
MIRT2459674	hsa-miR-4718	CLIP-seq
MIRT2459675	hsa-miR-4728-3p	CLIP-seq
MIRT1359194	hsa-miR-4753-5p	CLIP-seq
MIRT2459676	hsa-miR-4774-3p	CLIP-seq
MIRT2459671	hsa-miR-105	CLIP-seq
MIRT2459672	hsa-miR-3152-5p	CLIP-seq
MIRT2459673	hsa-miR-4663	CLIP-seq
MIRT2459675	hsa-miR-4728-3p	CLIP-seq
MIRT2459676	hsa-miR-4774-3p	CLIP-seq
MIRT2624685	hsa-miR-10a	CLIP-seq
MIRT2624686	hsa-miR-10b	CLIP-seq
MIRT2624687	hsa-miR-3160-3p	CLIP-seq
MIRT1359166	hsa-miR-3202	CLIP-seq
MIRT2624688	hsa-miR-339-5p	CLIP-seq
MIRT2624689	hsa-miR-3613-3p	CLIP-seq
MIRT1553759	hsa-miR-3622a-3p	CLIP-seq
MIRT1553760	hsa-miR-3622b-3p	CLIP-seq
MIRT2624690	hsa-miR-3662	CLIP-seq
MIRT2624691	hsa-miR-3685	CLIP-seq
MIRT1359175	hsa-miR-3714	CLIP-seq
MIRT2624692	hsa-miR-384	CLIP-seq
MIRT1553761	hsa-miR-3937	CLIP-seq
MIRT2624693	hsa-miR-4421	CLIP-seq
MIRT2106355	hsa-miR-4433	CLIP-seq
MIRT1359179	hsa-miR-4459	CLIP-seq
MIRT2624694	hsa-miR-4487	CLIP-seq
MIRT1359181	hsa-miR-4493	CLIP-seq
MIRT1359187	hsa-miR-4533	CLIP-seq
MIRT2624695	hsa-miR-4684-5p	CLIP-seq
MIRT2459674	hsa-miR-4718	CLIP-seq
MIRT1359194	hsa-miR-4753-5p	CLIP-seq
MIRT2330675	hsa-miR-4768-3p	CLIP-seq
MIRT2624696	hsa-miR-488	CLIP-seq
MIRT1553763	hsa-miR-544b	CLIP-seq
MIRT2624697	hsa-miR-548c-3p	CLIP-seq
MIRT2624698	hsa-miR-548l	CLIP-seq
MIRT2624699	hsa-miR-556-5p	CLIP-seq
MIRT2624700	hsa-miR-558	CLIP-seq
MIRT2624701	hsa-miR-593	CLIP-seq
MIRT1553764	hsa-miR-940	CLIP-seq
MIRT2624685	hsa-miR-10a	CLIP-seq
MIRT2624686	hsa-miR-10b	CLIP-seq
MIRT2691081	hsa-miR-3064-5p	CLIP-seq
MIRT1359166	hsa-miR-3202	CLIP-seq
MIRT2624688	hsa-miR-339-5p	CLIP-seq
MIRT2624689	hsa-miR-3613-3p	CLIP-seq
MIRT1553759	hsa-miR-3622a-3p	CLIP-seq
MIRT1553760	hsa-miR-3622b-3p	CLIP-seq
MIRT2624690	hsa-miR-3662	CLIP-seq
MIRT2624691	hsa-miR-3685	CLIP-seq
MIRT1359175	hsa-miR-3714	CLIP-seq
MIRT2624692	hsa-miR-384	CLIP-seq
MIRT1553761	hsa-miR-3937	CLIP-seq
MIRT2624693	hsa-miR-4421	CLIP-seq
MIRT2106355	hsa-miR-4433	CLIP-seq
MIRT1359179	hsa-miR-4459	CLIP-seq
MIRT1359181	hsa-miR-4493	CLIP-seq
MIRT1359187	hsa-miR-4533	CLIP-seq
MIRT2624695	hsa-miR-4684-5p	CLIP-seq
MIRT2459674	hsa-miR-4718	CLIP-seq
MIRT1359194	hsa-miR-4753-5p	CLIP-seq
MIRT2330675	hsa-miR-4768-3p	CLIP-seq
MIRT2624696	hsa-miR-488	CLIP-seq
MIRT1553763	hsa-miR-544b	CLIP-seq
MIRT2624697	hsa-miR-548c-3p	CLIP-seq
MIRT2624698	hsa-miR-548l	CLIP-seq
MIRT2624699	hsa-miR-556-5p	CLIP-seq
MIRT2624701	hsa-miR-593	CLIP-seq
MIRT1553764	hsa-miR-940	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005385	Function	Zinc ion transmembrane transporter activity	IBA
GO:0005385	Function	Zinc ion transmembrane transporter activity	IDA	17349999, 19521526
GO:0005385	Function	Zinc ion transmembrane transporter activity	IEA
GO:0005515	Function	Protein binding	IPI	25657003, 26728129, 32296183, 36204728
GO:0005737	Component	Cytoplasm	IDA	17349999
GO:0005764	Component	Lysosome	IEA
GO:0005765	Component	Lysosomal membrane	IEA
GO:0005768	Component	Endosome	IEA
GO:0005770	Component	Late endosome	IDA	17349999
GO:0005886	Component	Plasma membrane	IBA
GO:0006811	Process	Monoatomic ion transport	IEA
GO:0006812	Process	Monoatomic cation transport	IEA
GO:0006829	Process	Zinc ion transport	IEA
GO:0008324	Function	Monoatomic cation transmembrane transporter activity	IEA
GO:0009636	Process	Response to toxic substance	IDA	17575980
GO:0010008	Component	Endosome membrane	IEA
GO:0010008	Component	Endosome membrane	ISS
GO:0010043	Process	Response to zinc ion	IBA
GO:0015297	Function	Antiporter activity	IEA
GO:0016020	Component	Membrane	IEA
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0031902	Component	Late endosome membrane	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0055085	Process	Transmembrane transport	IEA
GO:0062111	Process	Zinc ion import into organelle	IEA
GO:0071577	Process	Zinc ion transmembrane transport	IBA
GO:0071577	Process	Zinc ion transmembrane transport	IDA	19521526
GO:0071577	Process	Zinc ion transmembrane transport	IEA
GO:0140882	Process	Zinc export across plasma membrane	IEA
GO:0140916	Process	Zinc ion import into lysosome	IDA	17349999

Other IDs

• MIM: 602095
• HGNC: 11015
• e!Ensembl: ENSG00000104154

Protein

• UniProt ID: O14863
• Protein name: Probable proton-coupled zinc antiporter SLC30A4 (Solute carrier family 30 member 4) (Zinc transporter 4) (ZnT-4)
• Protein function: Probable proton-coupled zinc ion antiporter mediating zinc import from cytoplasm potentially into the endocytic compartment (PubMed:19521526). Controls zinc deposition in milk (By similarity). {ECO:0000250|UniProtKB:O35149, ECO:0000305|PubMed:19
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01545	Cation_efflux	114 → 332	Cation efflux family	Family

• Sequence:

  MAGSGAWKRLKSMLRKDDAPLFLNDTSAFDFSDEAGDEGLSRFNKLRVVVADDGSEAPER
  PVNGAHPTLQADDDSLLDQDLPLTNSQLSLKVDSCDNCSKQREILKQRKVKARLTIAAVL
  YLLFMIGELVGGYIANSLAIMTDALHMLTDLSAIILTLLALWLSSKSPTKRFTFGFHRLE
  VLSAMISVLLVYILMGFLLYEAVQRTIHMNYEINGDIMLITAAVGVAVNVIMGFLLNQSG
  HRHSHSHSLPSNSPTRGSGCERNHGQDSLAVRAAFVHALGDLVQSVGVLIAAYIIRFKPE
  YKIADPICTYVFSLLVAFTTFRIIWDTVVIILEGVPSHLNVDYIKEALMKIEDVYSVEDL
  NIWSLTSGKSTAIVHIQLIPGSSSKWEEVQSKANHLLLNTFGMYRCTIQLQSYRQEVDRT
  CANCQSSSP

• Sequence length: 429

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ALZHEIMERS DISEASE	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Acrodermatitis	Dermatitis	LHGDN	11686514		★☆☆☆☆ Found in Text Mining only
Acrodermatitis enteropathica	Acrodermatitis Enteropathica	BEFREE	11511923, 11686514		★☆☆☆☆ Found in Text Mining only
Acute Confusional Senile Dementia	Senile Dementia	CTD_human_DG	16580781		★☆☆☆☆ Found in Text Mining only
Alzheimer Disease, Early Onset	Alzheimer disease	CTD_human_DG	16580781		★☆☆☆☆ Found in Text Mining only
Alzheimer Disease, Late Onset	Alzheimer disease	CTD_human_DG	16580781		★☆☆☆☆ Found in Text Mining only
Alzheimer`s Disease	Alzheimer disease	CTD_human_DG	16580781		★☆☆☆☆ Found in Text Mining only
Alzheimer`s Disease, Focal Onset	Alzheimer disease	CTD_human_DG	16580781		★☆☆☆☆ Found in Text Mining only
Catatonia	Catatonia	BEFREE	16697297		★☆☆☆☆ Found in Text Mining only
Cleft Lip with or without Cleft Palate	Cleft Lip With Or Without Cleft Palate	BEFREE	21478106		★☆☆☆☆ Found in Text Mining only
Depressive Disorder Major	Major depressive disorder	Pubtator	27661418	Stimulate	★☆☆☆☆ Found in Text Mining only
Dermatitis	Dermatitis	BEFREE	11686514		★☆☆☆☆ Found in Text Mining only
Familial Alzheimer Disease (FAD)	Alzheimer disease	CTD_human_DG	16580781		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	12955079		★☆☆☆☆ Found in Text Mining only
Presenile dementia	Senile Dementia	CTD_human_DG	16580781		★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	12955079		★☆☆☆☆ Found in Text Mining only
Prostatic Diseases	Prostatic Diseases	BEFREE	12955079		★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic Neoplasms	LHGDN	12955079		★☆☆☆☆ Found in Text Mining only
Schizophrenia, Catatonic	Schizophrenia	BEFREE	14628196		★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	33110097	Associate	★☆☆☆☆ Found in Text Mining only