Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	7730
Gene name	Zinc finger protein 177
Gene symbol	ZNF177
Synonyms (NCBI Gene)	PIGX
Chromosome	19
Chromosome location	19p13.2

Show/Hide all (88)

miRTarBase ID	miRNA	Experiments	Reference
MIRT708539	hsa-miR-345-3p	HITS-CLIP	19536157
MIRT708538	hsa-miR-4732-3p	HITS-CLIP	19536157
MIRT708537	hsa-miR-125a-5p	HITS-CLIP	19536157
MIRT708536	hsa-miR-125b-5p	HITS-CLIP	19536157
MIRT708535	hsa-miR-4319	HITS-CLIP	19536157
MIRT708534	hsa-miR-4324	HITS-CLIP	19536157
MIRT708533	hsa-miR-4329	HITS-CLIP	19536157
MIRT708532	hsa-miR-4524a-3p	HITS-CLIP	19536157
MIRT708531	hsa-miR-670-5p	HITS-CLIP	19536157
MIRT708530	hsa-miR-4755-5p	HITS-CLIP	19536157
MIRT708529	hsa-miR-5006-3p	HITS-CLIP	19536157
MIRT708528	hsa-miR-4446-5p	HITS-CLIP	19536157
MIRT708539	hsa-miR-345-3p	HITS-CLIP	19536157
MIRT708538	hsa-miR-4732-3p	HITS-CLIP	19536157
MIRT708537	hsa-miR-125a-5p	HITS-CLIP	19536157
MIRT708536	hsa-miR-125b-5p	HITS-CLIP	19536157
MIRT708535	hsa-miR-4319	HITS-CLIP	19536157
MIRT708534	hsa-miR-4324	HITS-CLIP	19536157
MIRT708533	hsa-miR-4329	HITS-CLIP	19536157
MIRT708532	hsa-miR-4524a-3p	HITS-CLIP	19536157
MIRT708531	hsa-miR-670-5p	HITS-CLIP	19536157
MIRT708530	hsa-miR-4755-5p	HITS-CLIP	19536157
MIRT708529	hsa-miR-5006-3p	HITS-CLIP	19536157
MIRT708528	hsa-miR-4446-5p	HITS-CLIP	19536157
MIRT1517136	hsa-miR-3938	CLIP-seq
MIRT1517137	hsa-miR-556-5p	CLIP-seq
MIRT1517138	hsa-miR-587	CLIP-seq
MIRT1517139	hsa-miR-103b	CLIP-seq
MIRT1517140	hsa-miR-1262	CLIP-seq
MIRT1517141	hsa-miR-3143	CLIP-seq
MIRT1517142	hsa-miR-320e	CLIP-seq
MIRT1517143	hsa-miR-4701-3p	CLIP-seq
MIRT1517144	hsa-miR-4729	CLIP-seq
MIRT1517145	hsa-miR-543	CLIP-seq
MIRT1517146	hsa-miR-548a-3p	CLIP-seq
MIRT1517147	hsa-miR-548e	CLIP-seq
MIRT1517148	hsa-miR-548f	CLIP-seq
MIRT1517149	hsa-miR-548g	CLIP-seq
MIRT1517150	hsa-miR-570	CLIP-seq
MIRT2668101	hsa-miR-101	CLIP-seq
MIRT1517139	hsa-miR-103b	CLIP-seq
MIRT2668102	hsa-miR-198	CLIP-seq
MIRT2668103	hsa-miR-2355-3p	CLIP-seq
MIRT2668104	hsa-miR-3064-3p	CLIP-seq
MIRT1517141	hsa-miR-3143	CLIP-seq
MIRT2668105	hsa-miR-3147	CLIP-seq
MIRT2668106	hsa-miR-338-3p	CLIP-seq
MIRT2668107	hsa-miR-34a	CLIP-seq
MIRT2668108	hsa-miR-34c-5p	CLIP-seq
MIRT2668109	hsa-miR-3671	CLIP-seq
MIRT2668110	hsa-miR-4259	CLIP-seq
MIRT2668111	hsa-miR-4302	CLIP-seq
MIRT2668112	hsa-miR-4464	CLIP-seq
MIRT2668113	hsa-miR-449a	CLIP-seq
MIRT2668114	hsa-miR-449b	CLIP-seq
MIRT2668115	hsa-miR-4530	CLIP-seq
MIRT2668116	hsa-miR-4640-5p	CLIP-seq
MIRT2668117	hsa-miR-4646-3p	CLIP-seq
MIRT2668118	hsa-miR-4697-3p	CLIP-seq
MIRT2668119	hsa-miR-4704-3p	CLIP-seq
MIRT2668120	hsa-miR-4717-3p	CLIP-seq
MIRT2668121	hsa-miR-4726-5p	CLIP-seq
MIRT1517144	hsa-miR-4729	CLIP-seq
MIRT2668122	hsa-miR-4748	CLIP-seq
MIRT2668123	hsa-miR-4762-5p	CLIP-seq
MIRT2668124	hsa-miR-4775	CLIP-seq
MIRT2668125	hsa-miR-499-3p	CLIP-seq
MIRT2668126	hsa-miR-499a-3p	CLIP-seq
MIRT2668127	hsa-miR-520a-5p	CLIP-seq
MIRT2668128	hsa-miR-525-5p	CLIP-seq
MIRT1517145	hsa-miR-543	CLIP-seq
MIRT2668129	hsa-miR-548ac	CLIP-seq
MIRT2668130	hsa-miR-548ae	CLIP-seq
MIRT2668131	hsa-miR-548aj	CLIP-seq
MIRT2668132	hsa-miR-548am	CLIP-seq
MIRT2668133	hsa-miR-548d-3p	CLIP-seq
MIRT2668134	hsa-miR-548x	CLIP-seq
MIRT2668135	hsa-miR-548z	CLIP-seq
MIRT2668136	hsa-miR-571	CLIP-seq
MIRT2668137	hsa-miR-590-3p	CLIP-seq
MIRT2668138	hsa-miR-607	CLIP-seq
MIRT2668107	hsa-miR-34a	CLIP-seq
MIRT2668108	hsa-miR-34c-5p	CLIP-seq
MIRT2668113	hsa-miR-449a	CLIP-seq
MIRT2668114	hsa-miR-449b	CLIP-seq
MIRT2668120	hsa-miR-4717-3p	CLIP-seq
MIRT2668124	hsa-miR-4775	CLIP-seq
MIRT2668137	hsa-miR-590-3p	CLIP-seq

Show/Hide all (14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	TAS	8661005
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0072562	Component	Blood microparticle	HDA	22516433
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IEA

MIM	HGNC	e!Ensembl
601276	12966	ENSG00000188629

Q13360

Protein name

Zinc finger protein 177

Protein function

May be involved in transcriptional regulation.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01352	KRAB	13 → 54	KRAB box	Family
PF13465	zf-H2C2_2	298 → 323		Domain
PF00096	zf-C2H2	340 → 362	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	368 → 390	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	396 → 418	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	424 → 446	Zinc finger, C2H2 type	Domain
PF13912	zf-C2H2_6	452 → 477		Domain

Sequence

MAAGWLTTWSQNSVTFQEVAVDFSQEEWALLDPAQKNLYKDVMLENFRNLASVGYQLCRH
SLISKVDQEQLKTDERGILQGDCADWETQLKPKDTIAMQNIPGGKTSNGINTAENQPGEH
SLECNHCGKFRKNTRFICTRYCKGEKCYKYIKYSKVFNHPSTLRSHVSIHIGEKTLEFTD
CRKAFNQESSLRKHLRTPTGQKFQEYEQCDMSFSLHSSCSVREQIPTGEKGDECSDYGKI
SPLSVHTKTGSVEEGLECNEHEKTFTDPLSLQNCVRTHSGEMPYECSDCGKAFIFQSSLK
KHMRSHTGEKPYECDHCGKSFSQSSHLNVHKRTHTGEKPYDCKECGKAFTVPSSLQKHVR
THTGEKPYECSDCGKAFIDQSSLKKHTRSHTGEKPYECNQCGKSFSTGSYLIVHKRTHTG
EKTYECKECGKAFRNSSCLRVHVRTHTGEKPYKCIQCEKAFSTSTNLIMHKRIHNGQKLH
E

Sequence length

481

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
STOMACH NEOPLASMS	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (10)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Breast Neoplasms	Breast neoplasm	Pubtator	33499882	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	31547144	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Endometrial Carcinoma	Endometrial carcinoma	BEFREE	26522113		★★★★★ ★☆☆☆☆ Found in Text Mining only
Endometrial Neoplasms	Endometrial neoplasm	Pubtator	26522113	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hereditary Diffuse Gastric Cancer	Gastric Cancer	CTD_human_DG	16367923		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	26842235	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of endometrium	Endometrial Cancer	BEFREE	26522113		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	CTD_human_DG	16367923		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach Neoplasms	CTD_human_DG	16367923		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Stomach Neoplasms	Stomach neoplasms	Pubtator	16367923	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

ZNF177 (zinc finger protein 177)