Gene Gene information from NCBI Gene database.
Entrez ID 7483
Gene name Wnt family member 9A
Gene symbol WNT9A
Synonyms (NCBI Gene)
WNT14
Chromosome 1
Chromosome location 1q42.13
Summary The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryoge
miRNA miRNA information provided by mirtarbase database.
511
miRTarBase ID miRNA Experiments Reference
MIRT016758 hsa-miR-335-5p Microarray 18185580
MIRT607337 hsa-miR-8485 HITS-CLIP 22927820
MIRT607336 hsa-miR-329-3p HITS-CLIP 22927820
MIRT607335 hsa-miR-362-3p HITS-CLIP 22927820
MIRT607334 hsa-miR-603 HITS-CLIP 22927820
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
21
GO ID Ontology Definition Evidence Reference
GO:0005102 Function Signaling receptor binding IEA
GO:0005109 Function Frizzled binding IBA
GO:0005125 Function Cytokine activity IBA
GO:0005515 Function Protein binding IPI 32296183
GO:0005576 Component Extracellular region IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
602863 12778 ENSG00000143816
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O14904
Protein name Protein Wnt-9a (Protein Wnt-14)
Protein function Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal timing of IHH expression during embryonic bone development, normal chondrocyte maturat
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00110 wnt 60 364 wnt family Family
Sequence
Sequence length 365
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  mTOR signaling pathway
Wnt signaling pathway
Hippo signaling pathway
Signaling pathways regulating pluripotency of stem cells
Melanogenesis
Cushing syndrome
Alzheimer disease
Pathways of neurodegeneration - multiple diseases
Human papillomavirus infection
Pathways in cancer
Proteoglycans in cancer
Basal cell carcinoma
Breast cancer
Hepatocellular carcinoma
Gastric cancer
  WNT ligand biogenesis and trafficking
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
MOYAMOYA DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
PARKINSON DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Breast Carcinoma Breast Carcinoma BEFREE 15809769
★☆☆☆☆
Found in Text Mining only
Carcinoma Hepatocellular Hepatocellular carcinoma Pubtator 34902334 Associate
★☆☆☆☆
Found in Text Mining only
Carpal Tunnel Syndrome Carpal tunnel syndrome Pubtator 26174360 Stimulate
★☆☆☆☆
Found in Text Mining only
Colorectal Neoplasms Colorectal neoplasm Pubtator 27049382 Associate
★☆☆☆☆
Found in Text Mining only
Connective Tissue Diseases Connective Tissue Disease BEFREE 12011973
★☆☆☆☆
Found in Text Mining only
Dementia Dementia Pubtator 37175824 Associate
★☆☆☆☆
Found in Text Mining only
Hyperandrogenism Hyperandrogenism BEFREE 28434104
★☆☆☆☆
Found in Text Mining only
Kidney Diseases Kidney Disease BEFREE 29440280
★☆☆☆☆
Found in Text Mining only
Lymphoid leukemia Lymphoid leukemia BEFREE 16707430
★☆☆☆☆
Found in Text Mining only
Malignant neoplasm of breast Breast Cancer BEFREE 15809769
★☆☆☆☆
Found in Text Mining only