UQCRB (ubiquinol-cytochrome c reductase binding protein)

Gene

• Entrez ID: 7381
• Gene name: Ubiquinol-cytochrome c reductase binding protein
• Gene symbol: UQCRB
• Synonyms (NCBI Gene): MC3DN3, QCR7, QP-C, QPC, UQBC, UQBP, UQCR6, UQPC
• Chromosome: 8
• Chromosome location: 8q22.1
• Summary: This gene encodes a subunit of the ubiquinol-cytochrome c oxidoreductase complex, which consists of one mitochondrial-encoded and 10 nuclear-encoded subunits. The protein encoded by this gene binds ubiquinone and participates in the transfer of electrons

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs139283183	A>T	Conflicting-interpretations-of-pathogenicity	Non coding transcript variant, missense variant, coding sequence variant
rs863224257	T>A	Likely-pathogenic	5 prime UTR variant, non coding transcript variant, coding sequence variant, missense variant
rs863224258	C>A,T	Likely-pathogenic	Non coding transcript variant, stop gained, 3 prime UTR variant, missense variant, coding sequence variant
rs863224259	C>-	Pathogenic	Frameshift variant, non coding transcript variant, coding sequence variant
rs886043294	TTTT>-	Pathogenic	3 prime UTR variant, frameshift variant, non coding transcript variant, coding sequence variant
rs1554577679	C>A	Likely-pathogenic	Coding sequence variant, 3 prime UTR variant, stop gained, non coding transcript variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT042467	hsa-miR-423-3p	CLASH	23622248
MIRT640375	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT640374	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT640373	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT640372	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT640371	hsa-miR-4641	HITS-CLIP	23824327
MIRT640370	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT640369	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT640368	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT640367	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT631100	hsa-miR-4781-3p	HITS-CLIP	23824327
MIRT631099	hsa-miR-4716-5p	HITS-CLIP	23824327
MIRT631098	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT631097	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT631096	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT631095	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT631094	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT631093	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT631092	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT631091	hsa-miR-6131	HITS-CLIP	23824327
MIRT631090	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT631089	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT631088	hsa-miR-1200	HITS-CLIP	23824327
MIRT631087	hsa-miR-548s	HITS-CLIP	23824327
MIRT631086	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT631085	hsa-miR-588	HITS-CLIP	23824327
MIRT631084	hsa-miR-4435	HITS-CLIP	23824327
MIRT631083	hsa-miR-3187-3p	HITS-CLIP	23824327
MIRT631082	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT631081	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT631080	hsa-miR-5096	HITS-CLIP	23824327
MIRT505203	hsa-miR-499a-3p	PAR-CLIP	22012620
MIRT505202	hsa-miR-499b-3p	PAR-CLIP	22012620
MIRT505201	hsa-miR-21-5p	PAR-CLIP	22012620
MIRT505200	hsa-miR-590-5p	PAR-CLIP	22012620
MIRT505199	hsa-miR-1244	PAR-CLIP	22012620
MIRT505198	hsa-miR-7705	PAR-CLIP	22012620
MIRT505197	hsa-miR-16-1-3p	PAR-CLIP	22012620
MIRT505196	hsa-miR-5579-3p	PAR-CLIP	22012620
MIRT505195	hsa-miR-411-5p	PAR-CLIP	22012620
MIRT505203	hsa-miR-499a-3p	PAR-CLIP	23446348
MIRT505202	hsa-miR-499b-3p	PAR-CLIP	23446348
MIRT505201	hsa-miR-21-5p	PAR-CLIP	23446348
MIRT505200	hsa-miR-590-5p	PAR-CLIP	23446348
MIRT505199	hsa-miR-1244	PAR-CLIP	23446348
MIRT505198	hsa-miR-7705	PAR-CLIP	23446348
MIRT505197	hsa-miR-16-1-3p	PAR-CLIP	23446348
MIRT505196	hsa-miR-5579-3p	PAR-CLIP	23446348
MIRT505195	hsa-miR-411-5p	PAR-CLIP	23446348
MIRT505203	hsa-miR-499a-3p	PAR-CLIP	23446348
MIRT505202	hsa-miR-499b-3p	PAR-CLIP	23446348
MIRT505201	hsa-miR-21-5p	PAR-CLIP	23446348
MIRT505200	hsa-miR-590-5p	PAR-CLIP	23446348
MIRT505199	hsa-miR-1244	PAR-CLIP	23446348
MIRT505198	hsa-miR-7705	PAR-CLIP	23446348
MIRT505197	hsa-miR-16-1-3p	PAR-CLIP	23446348
MIRT505196	hsa-miR-5579-3p	PAR-CLIP	23446348
MIRT505195	hsa-miR-411-5p	PAR-CLIP	23446348
MIRT449151	hsa-miR-130a-3p	PAR-CLIP	22100165
MIRT449150	hsa-miR-130b-3p	PAR-CLIP	22100165
MIRT449149	hsa-miR-301a-3p	PAR-CLIP	22100165
MIRT449148	hsa-miR-301b-3p	PAR-CLIP	22100165
MIRT449147	hsa-miR-3666	PAR-CLIP	22100165
MIRT449146	hsa-miR-4295	PAR-CLIP	22100165
MIRT449145	hsa-miR-454-3p	PAR-CLIP	22100165
MIRT449144	hsa-miR-4424	PAR-CLIP	22100165
MIRT449143	hsa-miR-2467-3p	PAR-CLIP	22100165
MIRT449142	hsa-miR-569	PAR-CLIP	22100165
MIRT449141	hsa-miR-155-5p	PAR-CLIP	22100165
MIRT449140	hsa-miR-4671-3p	PAR-CLIP	22100165
MIRT449138	hsa-miR-4473	PAR-CLIP	22100165
MIRT449139	hsa-miR-3678-3p	PAR-CLIP	22100165
MIRT449137	hsa-miR-1273e	PAR-CLIP	22100165
MIRT640375	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT640374	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT640373	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT640372	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT640371	hsa-miR-4641	HITS-CLIP	23824327
MIRT640370	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT640369	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT640368	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT640367	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT631100	hsa-miR-4781-3p	HITS-CLIP	23824327
MIRT631099	hsa-miR-4716-5p	HITS-CLIP	23824327
MIRT631098	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT631097	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT631096	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT631095	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT631094	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT631093	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT631092	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT631091	hsa-miR-6131	HITS-CLIP	23824327
MIRT631090	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT631089	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT631088	hsa-miR-1200	HITS-CLIP	23824327
MIRT631087	hsa-miR-548s	HITS-CLIP	23824327
MIRT631086	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT631085	hsa-miR-588	HITS-CLIP	23824327
MIRT631084	hsa-miR-4435	HITS-CLIP	23824327
MIRT631083	hsa-miR-3187-3p	HITS-CLIP	23824327
MIRT631082	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT631081	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT631080	hsa-miR-5096	HITS-CLIP	23824327
MIRT505203	hsa-miR-499a-3p	PAR-CLIP	22012620
MIRT505202	hsa-miR-499b-3p	PAR-CLIP	22012620
MIRT505201	hsa-miR-21-5p	PAR-CLIP	22012620
MIRT505200	hsa-miR-590-5p	PAR-CLIP	22012620
MIRT505199	hsa-miR-1244	PAR-CLIP	22012620
MIRT505198	hsa-miR-7705	PAR-CLIP	22012620
MIRT505197	hsa-miR-16-1-3p	PAR-CLIP	22012620
MIRT505196	hsa-miR-5579-3p	PAR-CLIP	22012620
MIRT505195	hsa-miR-411-5p	PAR-CLIP	22012620
MIRT505203	hsa-miR-499a-3p	PAR-CLIP	23446348
MIRT505202	hsa-miR-499b-3p	PAR-CLIP	23446348
MIRT505201	hsa-miR-21-5p	PAR-CLIP	23446348
MIRT505200	hsa-miR-590-5p	PAR-CLIP	23446348
MIRT505199	hsa-miR-1244	PAR-CLIP	23446348
MIRT505198	hsa-miR-7705	PAR-CLIP	23446348
MIRT505197	hsa-miR-16-1-3p	PAR-CLIP	23446348
MIRT505196	hsa-miR-5579-3p	PAR-CLIP	23446348
MIRT505195	hsa-miR-411-5p	PAR-CLIP	23446348
MIRT505203	hsa-miR-499a-3p	PAR-CLIP	23446348
MIRT505202	hsa-miR-499b-3p	PAR-CLIP	23446348
MIRT505201	hsa-miR-21-5p	PAR-CLIP	23446348
MIRT505200	hsa-miR-590-5p	PAR-CLIP	23446348
MIRT505199	hsa-miR-1244	PAR-CLIP	23446348
MIRT505198	hsa-miR-7705	PAR-CLIP	23446348
MIRT505197	hsa-miR-16-1-3p	PAR-CLIP	23446348
MIRT505196	hsa-miR-5579-3p	PAR-CLIP	23446348
MIRT505195	hsa-miR-411-5p	PAR-CLIP	23446348
MIRT449151	hsa-miR-130a-3p	PAR-CLIP	22100165
MIRT449150	hsa-miR-130b-3p	PAR-CLIP	22100165
MIRT449149	hsa-miR-301a-3p	PAR-CLIP	22100165
MIRT449148	hsa-miR-301b-3p	PAR-CLIP	22100165
MIRT449147	hsa-miR-3666	PAR-CLIP	22100165
MIRT449146	hsa-miR-4295	PAR-CLIP	22100165
MIRT449145	hsa-miR-454-3p	PAR-CLIP	22100165
MIRT449144	hsa-miR-4424	PAR-CLIP	22100165
MIRT449143	hsa-miR-2467-3p	PAR-CLIP	22100165
MIRT449142	hsa-miR-569	PAR-CLIP	22100165
MIRT449141	hsa-miR-155-5p	PAR-CLIP	22100165
MIRT449140	hsa-miR-4671-3p	PAR-CLIP	22100165
MIRT449138	hsa-miR-4473	PAR-CLIP	22100165
MIRT449139	hsa-miR-3678-3p	PAR-CLIP	22100165
MIRT449137	hsa-miR-1273e	PAR-CLIP	22100165
MIRT1476590	hsa-miR-1272	CLIP-seq
MIRT1476591	hsa-miR-1276	CLIP-seq
MIRT1476592	hsa-miR-1289	CLIP-seq
MIRT1476593	hsa-miR-1297	CLIP-seq
MIRT1476594	hsa-miR-132	CLIP-seq
MIRT1476595	hsa-miR-199a-3p	CLIP-seq
MIRT1476596	hsa-miR-199b-3p	CLIP-seq
MIRT1476597	hsa-miR-205	CLIP-seq
MIRT1476598	hsa-miR-212	CLIP-seq
MIRT1476599	hsa-miR-214	CLIP-seq
MIRT1476600	hsa-miR-223	CLIP-seq
MIRT1476601	hsa-miR-26a	CLIP-seq
MIRT1476602	hsa-miR-26b	CLIP-seq
MIRT1476603	hsa-miR-3064-3p	CLIP-seq
MIRT1476604	hsa-miR-3074-5p	CLIP-seq
MIRT1476605	hsa-miR-3120-3p	CLIP-seq
MIRT1476606	hsa-miR-3121-5p	CLIP-seq
MIRT1476607	hsa-miR-3129-3p	CLIP-seq
MIRT1476608	hsa-miR-3129-5p	CLIP-seq
MIRT1476609	hsa-miR-3140-5p	CLIP-seq
MIRT1476610	hsa-miR-3163	CLIP-seq
MIRT1476611	hsa-miR-3619-5p	CLIP-seq
MIRT1476612	hsa-miR-371b-3p	CLIP-seq
MIRT1476613	hsa-miR-3908	CLIP-seq
MIRT1476614	hsa-miR-4266	CLIP-seq
MIRT1476615	hsa-miR-4282	CLIP-seq
MIRT1476616	hsa-miR-4291	CLIP-seq
MIRT1476617	hsa-miR-4307	CLIP-seq
MIRT1476618	hsa-miR-4311	CLIP-seq
MIRT1476619	hsa-miR-4317	CLIP-seq
MIRT1476620	hsa-miR-4465	CLIP-seq
MIRT1476621	hsa-miR-4490	CLIP-seq
MIRT1476622	hsa-miR-4519	CLIP-seq
MIRT1476623	hsa-miR-4668-3p	CLIP-seq
MIRT1476624	hsa-miR-4722-3p	CLIP-seq
MIRT1476625	hsa-miR-4738-3p	CLIP-seq
MIRT1476626	hsa-miR-4756-3p	CLIP-seq
MIRT1476627	hsa-miR-4774-5p	CLIP-seq
MIRT1476628	hsa-miR-4775	CLIP-seq
MIRT1476629	hsa-miR-489	CLIP-seq
MIRT1476630	hsa-miR-498	CLIP-seq
MIRT1476631	hsa-miR-520d-5p	CLIP-seq
MIRT1476632	hsa-miR-524-5p	CLIP-seq
MIRT1476633	hsa-miR-548a-3p	CLIP-seq
MIRT1476634	hsa-miR-548a-5p	CLIP-seq
MIRT1476635	hsa-miR-548ab	CLIP-seq
MIRT1476636	hsa-miR-548ak	CLIP-seq
MIRT1476637	hsa-miR-548b-5p	CLIP-seq
MIRT1476638	hsa-miR-548c-5p	CLIP-seq
MIRT1476639	hsa-miR-548d-5p	CLIP-seq
MIRT1476640	hsa-miR-548e	CLIP-seq
MIRT1476641	hsa-miR-548f	CLIP-seq
MIRT1476642	hsa-miR-548h	CLIP-seq
MIRT1476643	hsa-miR-548i	CLIP-seq
MIRT1476644	hsa-miR-548j	CLIP-seq
MIRT1476645	hsa-miR-548k	CLIP-seq
MIRT1476646	hsa-miR-548l	CLIP-seq
MIRT1476647	hsa-miR-548w	CLIP-seq
MIRT1476648	hsa-miR-548y	CLIP-seq
MIRT1476649	hsa-miR-549	CLIP-seq
MIRT1476650	hsa-miR-559	CLIP-seq
MIRT1476651	hsa-miR-567	CLIP-seq
MIRT1476652	hsa-miR-583	CLIP-seq
MIRT1476653	hsa-miR-590-3p	CLIP-seq
MIRT1476654	hsa-miR-761	CLIP-seq
MIRT1476655	hsa-miR-922	CLIP-seq
MIRT1476656	hsa-miR-935	CLIP-seq
MIRT1476657	hsa-miR-936	CLIP-seq
MIRT1476658	hsa-miR-938	CLIP-seq
MIRT1476659	hsa-miR-128	CLIP-seq
MIRT1476599	hsa-miR-214	CLIP-seq
MIRT1476660	hsa-miR-3121-3p	CLIP-seq
MIRT1476661	hsa-miR-3155	CLIP-seq
MIRT1476662	hsa-miR-3155b	CLIP-seq
MIRT1476663	hsa-miR-338-3p	CLIP-seq
MIRT1476664	hsa-miR-3616-5p	CLIP-seq
MIRT1476611	hsa-miR-3619-5p	CLIP-seq
MIRT1476665	hsa-miR-3647-5p	CLIP-seq
MIRT1476666	hsa-miR-3650	CLIP-seq
MIRT1476667	hsa-miR-3925-3p	CLIP-seq
MIRT1476668	hsa-miR-3929	CLIP-seq
MIRT1476669	hsa-miR-4419b	CLIP-seq
MIRT1476670	hsa-miR-4434	CLIP-seq
MIRT1476671	hsa-miR-4478	CLIP-seq
MIRT1476672	hsa-miR-4516	CLIP-seq
MIRT1476673	hsa-miR-4530	CLIP-seq
MIRT1476674	hsa-miR-4531	CLIP-seq
MIRT1476675	hsa-miR-4672	CLIP-seq
MIRT1476676	hsa-miR-4795-5p	CLIP-seq
MIRT1476677	hsa-miR-484	CLIP-seq
MIRT1476678	hsa-miR-512-3p	CLIP-seq
MIRT1476679	hsa-miR-519a	CLIP-seq
MIRT1476680	hsa-miR-519b-3p	CLIP-seq
MIRT1476681	hsa-miR-519c-3p	CLIP-seq
MIRT1476682	hsa-miR-520f	CLIP-seq
MIRT1476683	hsa-miR-539	CLIP-seq
MIRT1476684	hsa-miR-573	CLIP-seq
MIRT1476685	hsa-miR-587	CLIP-seq
MIRT1476654	hsa-miR-761	CLIP-seq
MIRT1476686	hsa-miR-766	CLIP-seq
MIRT1476594	hsa-miR-132	CLIP-seq
MIRT1476595	hsa-miR-199a-3p	CLIP-seq
MIRT1476596	hsa-miR-199b-3p	CLIP-seq
MIRT1476598	hsa-miR-212	CLIP-seq
MIRT1476608	hsa-miR-3129-5p	CLIP-seq
MIRT1476657	hsa-miR-936	CLIP-seq
MIRT2143601	hsa-miR-106a	CLIP-seq
MIRT2143602	hsa-miR-106b	CLIP-seq
MIRT2143603	hsa-miR-17	CLIP-seq
MIRT2143604	hsa-miR-20a	CLIP-seq
MIRT2143605	hsa-miR-20b	CLIP-seq
MIRT1476661	hsa-miR-3155	CLIP-seq
MIRT1476662	hsa-miR-3155b	CLIP-seq
MIRT1476664	hsa-miR-3616-5p	CLIP-seq
MIRT1476665	hsa-miR-3647-5p	CLIP-seq
MIRT1476666	hsa-miR-3650	CLIP-seq
MIRT2143606	hsa-miR-3662	CLIP-seq
MIRT2143607	hsa-miR-376c	CLIP-seq
MIRT1476668	hsa-miR-3929	CLIP-seq
MIRT2143608	hsa-miR-4279	CLIP-seq
MIRT1476669	hsa-miR-4419b	CLIP-seq
MIRT1476671	hsa-miR-4478	CLIP-seq
MIRT2143609	hsa-miR-4707-3p	CLIP-seq
MIRT2143610	hsa-miR-4772-3p	CLIP-seq
MIRT1476676	hsa-miR-4795-5p	CLIP-seq
MIRT2143611	hsa-miR-4796-3p	CLIP-seq
MIRT1476677	hsa-miR-484	CLIP-seq
MIRT1476679	hsa-miR-519a	CLIP-seq
MIRT1476680	hsa-miR-519b-3p	CLIP-seq
MIRT1476681	hsa-miR-519c-3p	CLIP-seq
MIRT2143612	hsa-miR-519d	CLIP-seq
MIRT1476631	hsa-miR-520d-5p	CLIP-seq
MIRT2143613	hsa-miR-520g	CLIP-seq
MIRT2143614	hsa-miR-520h	CLIP-seq
MIRT1476632	hsa-miR-524-5p	CLIP-seq
MIRT1476684	hsa-miR-573	CLIP-seq
MIRT2143615	hsa-miR-764	CLIP-seq
MIRT2143616	hsa-miR-93	CLIP-seq
MIRT1476591	hsa-miR-1276	CLIP-seq
MIRT1476600	hsa-miR-223	CLIP-seq
MIRT1476661	hsa-miR-3155	CLIP-seq
MIRT1476662	hsa-miR-3155b	CLIP-seq
MIRT2363826	hsa-miR-330-3p	CLIP-seq
MIRT2363827	hsa-miR-342-5p	CLIP-seq
MIRT1476664	hsa-miR-3616-5p	CLIP-seq
MIRT1476665	hsa-miR-3647-5p	CLIP-seq
MIRT1476666	hsa-miR-3650	CLIP-seq
MIRT1476668	hsa-miR-3929	CLIP-seq
MIRT2363828	hsa-miR-411	CLIP-seq
MIRT1476619	hsa-miR-4317	CLIP-seq
MIRT1476669	hsa-miR-4419b	CLIP-seq
MIRT1476671	hsa-miR-4478	CLIP-seq
MIRT2363829	hsa-miR-4480	CLIP-seq
MIRT2363830	hsa-miR-4664-5p	CLIP-seq
MIRT1476628	hsa-miR-4775	CLIP-seq
MIRT1476676	hsa-miR-4795-5p	CLIP-seq
MIRT1476677	hsa-miR-484	CLIP-seq
MIRT2363831	hsa-miR-513b	CLIP-seq
MIRT1476679	hsa-miR-519a	CLIP-seq
MIRT1476680	hsa-miR-519b-3p	CLIP-seq
MIRT1476681	hsa-miR-519c-3p	CLIP-seq
MIRT1476684	hsa-miR-573	CLIP-seq
MIRT1476653	hsa-miR-590-3p	CLIP-seq
MIRT1476656	hsa-miR-935	CLIP-seq
MIRT1476595	hsa-miR-199a-3p	CLIP-seq
MIRT1476596	hsa-miR-199b-3p	CLIP-seq
MIRT1476608	hsa-miR-3129-5p	CLIP-seq
MIRT1476593	hsa-miR-1297	CLIP-seq
MIRT1476601	hsa-miR-26a	CLIP-seq
MIRT1476602	hsa-miR-26b	CLIP-seq
MIRT2434457	hsa-miR-324-5p	CLIP-seq
MIRT1476620	hsa-miR-4465	CLIP-seq
MIRT1476630	hsa-miR-498	CLIP-seq
MIRT2434458	hsa-miR-499a-5p	CLIP-seq
MIRT1476594	hsa-miR-132	CLIP-seq
MIRT1476595	hsa-miR-199a-3p	CLIP-seq
MIRT1476596	hsa-miR-199b-3p	CLIP-seq
MIRT1476598	hsa-miR-212	CLIP-seq
MIRT1476608	hsa-miR-3129-5p	CLIP-seq
MIRT1476657	hsa-miR-936	CLIP-seq
MIRT1476594	hsa-miR-132	CLIP-seq
MIRT1476595	hsa-miR-199a-3p	CLIP-seq
MIRT1476596	hsa-miR-199b-3p	CLIP-seq
MIRT1476598	hsa-miR-212	CLIP-seq
MIRT1476608	hsa-miR-3129-5p	CLIP-seq
MIRT1476657	hsa-miR-936	CLIP-seq
MIRT1476666	hsa-miR-3650	CLIP-seq
MIRT2657622	hsa-miR-129-5p	CLIP-seq
MIRT2657623	hsa-miR-130a	CLIP-seq
MIRT2657624	hsa-miR-130b	CLIP-seq
MIRT2657625	hsa-miR-1321	CLIP-seq
MIRT2657626	hsa-miR-196a	CLIP-seq
MIRT2657627	hsa-miR-196b	CLIP-seq
MIRT2657628	hsa-miR-2355-3p	CLIP-seq
MIRT2657629	hsa-miR-301a	CLIP-seq
MIRT2657630	hsa-miR-301b	CLIP-seq
MIRT2657631	hsa-miR-3148	CLIP-seq
MIRT2657632	hsa-miR-3149	CLIP-seq
MIRT2657633	hsa-miR-3194-5p	CLIP-seq
MIRT2657634	hsa-miR-3690	CLIP-seq
MIRT2657635	hsa-miR-3927	CLIP-seq
MIRT2657636	hsa-miR-4254	CLIP-seq
MIRT2657637	hsa-miR-4270	CLIP-seq
MIRT2657638	hsa-miR-4441	CLIP-seq
MIRT2657639	hsa-miR-454	CLIP-seq
MIRT2657640	hsa-miR-4709-5p	CLIP-seq
MIRT2657641	hsa-miR-4735-5p	CLIP-seq
MIRT2657642	hsa-miR-4739	CLIP-seq
MIRT2657643	hsa-miR-4756-5p	CLIP-seq
MIRT1476628	hsa-miR-4775	CLIP-seq
MIRT2657644	hsa-miR-4803	CLIP-seq
MIRT2657645	hsa-miR-485-5p	CLIP-seq
MIRT2657646	hsa-miR-548aa	CLIP-seq
MIRT1476653	hsa-miR-590-3p	CLIP-seq
MIRT2657647	hsa-miR-676	CLIP-seq
MIRT2657648	hsa-miR-875-3p	CLIP-seq
MIRT2657622	hsa-miR-129-5p	CLIP-seq
MIRT2657623	hsa-miR-130a	CLIP-seq
MIRT2657624	hsa-miR-130b	CLIP-seq
MIRT2657626	hsa-miR-196a	CLIP-seq
MIRT2657627	hsa-miR-196b	CLIP-seq
MIRT2657629	hsa-miR-301a	CLIP-seq
MIRT2657630	hsa-miR-301b	CLIP-seq
MIRT2657632	hsa-miR-3149	CLIP-seq
MIRT2657635	hsa-miR-3927	CLIP-seq
MIRT2363828	hsa-miR-411	CLIP-seq
MIRT2143608	hsa-miR-4279	CLIP-seq
MIRT2694786	hsa-miR-4469	CLIP-seq
MIRT2657639	hsa-miR-454	CLIP-seq
MIRT2657640	hsa-miR-4709-5p	CLIP-seq
MIRT2657641	hsa-miR-4735-5p	CLIP-seq
MIRT2694787	hsa-miR-4740-3p	CLIP-seq
MIRT1476628	hsa-miR-4775	CLIP-seq
MIRT2657644	hsa-miR-4803	CLIP-seq
MIRT1476653	hsa-miR-590-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	16189514, 25416956, 28514442, 32296183, 32814053, 33961781
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IEA
GO:0005743	Component	Mitochondrial inner membrane	IDA	28844695
GO:0005743	Component	Mitochondrial inner membrane	IEA
GO:0005743	Component	Mitochondrial inner membrane	TAS
GO:0006119	Process	Oxidative phosphorylation	TAS	3056408
GO:0006122	Process	Mitochondrial electron transport, ubiquinol to cytochrome c	IBA
GO:0006122	Process	Mitochondrial electron transport, ubiquinol to cytochrome c	IEA
GO:0006122	Process	Mitochondrial electron transport, ubiquinol to cytochrome c	NAS	28844695
GO:0009060	Process	Aerobic respiration	TAS	3056408
GO:0016020	Component	Membrane	IEA
GO:0045275	Component	Respiratory chain complex III	IBA
GO:0045275	Component	Respiratory chain complex III	IEA
GO:0045333	Process	Cellular respiration	NAS	28844695
GO:0098803	Component	Respiratory chain complex	TAS	3056408

Other IDs

• MIM: 191330
• HGNC: 12582
• e!Ensembl: ENSG00000156467

Protein

• UniProt ID: P14927
• Protein name: Cytochrome b-c1 complex subunit 7 (Complex III subunit 7) (Complex III subunit VII) (QP-C) (Ubiquinol-cytochrome c reductase complex 14 kDa protein)
• Protein function: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complex
• PDB: 5XTE, 5XTH, 5XTI
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02271	UCR_14kD	8 → 106	Ubiquinol-cytochrome C reductase complex 14kD subunit	Family

• Sequence:

  MAGKQAVSASGKWLDGIRKWYYNAAGFNKLGLMRDDTIYEDEDVKEAIRRLPENLYNDRM
  FRIKRALDLNLKHQILPKEQWTKYEEENFYLEPYLKEVIRERKEREEWAKK

• Sequence length: 111

Pathways

KEGG:

Oxidative phosphorylation
Metabolic pathways
Cardiac muscle contraction
Thermogenesis
Non-alcoholic fatty liver disease
Alzheimer disease
Parkinson disease
Amyotrophic lateral sclerosis
Huntington disease
Prion disease
Pathways of neurodegeneration - multiple diseases
Chemical carcinogenesis - reactive oxygen species
Diabetic cardiomyopathy

Reactome:

Respiratory electron transport

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
DIVERTICULAR DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MITOCHONDRIAL COMPLEX III DEFICIENCY	—	CTD, ClinVar, Disgenet CTD, ClinVar, Disgenet CTD, ClinVar, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Mitochondrial complex III deficiency nuclear type 3	Benign; Conflicting classifications of pathogenicity; Likely benign	ClinVar ClinVar, GenCC	★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
MITOCHONDRIAL COMPLEX III DEFICIENCY, NUCLEAR TYPE 1	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MITOCHONDRIAL COMPLEX III DEFICIENCY, NUCLEAR TYPE 3	—	Disgenet, HPO Disgenet, HPO	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
UQCRB-related disorder	Likely benign; Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Alzheimer Disease	Alzheimer disease	Pubtator	36405716	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	30120311	Associate	★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Colonic neoplasm	Pubtator	22545919	Associate	★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	29147009		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	22545919, 29147009, 32071343	Associate	★☆☆☆☆ Found in Text Mining only
Complete atrioventricular block	Complete Atrioventricular Block	BEFREE	27497639		★☆☆☆☆ Found in Text Mining only
Depressive disorder	Mental Depression	BEFREE	28697555		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	37091853	Associate	★☆☆☆☆ Found in Text Mining only
Hypoglycemia	Hypoglycemia	BEFREE	12709789		★☆☆☆☆ Found in Text Mining only
Hypoglycemia	Hypoglycemia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Isolated complex III deficiency	Isolated Complex III Deficiency	Orphanet			★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	17317821, 24369324		★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	22545919	Associate	★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of liver	Liver Cancer	BEFREE	30120311		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	29115404		★☆☆☆☆ Found in Text Mining only
Mental Depression	Mental Depression	BEFREE	28697555		★☆☆☆☆ Found in Text Mining only
Metabolic Diseases	Metabolic Diseases	BEFREE	25446085		★☆☆☆☆ Found in Text Mining only
Mitochondrial Complex III Deficiency	Mitochondrial complex deficiency	Pubtator	29147009	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MITOCHONDRIAL COMPLEX III DEFICIENCY (disorder)	Mitochondrial Complex Deficiency	CTD_human_DG			★☆☆☆☆ Found in Text Mining only
MITOCHONDRIAL COMPLEX III DEFICIENCY, NUCLEAR TYPE 3	Mitochondrial Complex Deficiency	GENOMICS_ENGLAND_DG	12709789, 18439546, 23454382, 28604960		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Mitochondrial Diseases	Mitochondrial Diseases	GENOMICS_ENGLAND_DG	23454382		★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	22174824	Associate	★☆☆☆☆ Found in Text Mining only