UBE2B (ubiquitin conjugating enzyme E2 B)

Gene

• Entrez ID: 7320
• Gene name: Ubiquitin conjugating enzyme E2 B
• Gene symbol: UBE2B
• Synonyms (NCBI Gene): E2-17kDa, HHR6B, HR6B, RAD6B, UBC2
• Chromosome: 5
• Chromosome location: 5q31.1
• Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conju

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT027247	hsa-miR-101-3p	Sequencing	20371350
MIRT697902	hsa-miR-4438	HITS-CLIP	23313552
MIRT553190	hsa-miR-6504-3p	HITS-CLIP	23313552
MIRT697901	hsa-miR-4269	HITS-CLIP	23313552
MIRT697899	hsa-miR-6715b-5p	HITS-CLIP	23313552
MIRT697900	hsa-miR-4740-3p	HITS-CLIP	23313552
MIRT697898	hsa-miR-4722-3p	HITS-CLIP	23313552
MIRT697897	hsa-miR-6727-3p	HITS-CLIP	23313552
MIRT697896	hsa-miR-6747-3p	HITS-CLIP	23313552
MIRT697895	hsa-miR-619-5p	HITS-CLIP	23313552
MIRT697894	hsa-miR-6506-5p	HITS-CLIP	23313552
MIRT697893	hsa-miR-6804-3p	HITS-CLIP	23313552
MIRT697892	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT697891	hsa-miR-4763-5p	HITS-CLIP	23313552
MIRT697889	hsa-miR-5095	HITS-CLIP	23313552
MIRT697890	hsa-miR-7151-3p	HITS-CLIP	23313552
MIRT697888	hsa-miR-4715-3p	HITS-CLIP	23313552
MIRT697887	hsa-miR-5089-5p	HITS-CLIP	23313552
MIRT697886	hsa-miR-3174	HITS-CLIP	23313552
MIRT697885	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT697884	hsa-miR-3190-5p	HITS-CLIP	23313552
MIRT697883	hsa-miR-4524a-3p	HITS-CLIP	23313552
MIRT697882	hsa-miR-4786-5p	HITS-CLIP	23313552
MIRT697881	hsa-miR-769-5p	HITS-CLIP	23313552
MIRT697880	hsa-miR-3926	HITS-CLIP	23313552
MIRT697879	hsa-miR-921	HITS-CLIP	23313552
MIRT697878	hsa-miR-3672	HITS-CLIP	23313552
MIRT697877	hsa-miR-6864-3p	HITS-CLIP	23313552
MIRT697876	hsa-miR-548s	HITS-CLIP	23313552
MIRT553192	hsa-miR-377-3p	PAR-CLIP	21572407
MIRT311711	hsa-miR-3942-5p	PAR-CLIP	21572407
MIRT311713	hsa-miR-4703-5p	PAR-CLIP	21572407
MIRT553191	hsa-miR-5000-5p	PAR-CLIP	21572407
MIRT553190	hsa-miR-6504-3p	PAR-CLIP	21572407
MIRT553189	hsa-miR-1228-3p	PAR-CLIP	21572407
MIRT553188	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT553187	hsa-miR-107	PAR-CLIP	21572407
MIRT553186	hsa-miR-520d-5p	PAR-CLIP	21572407
MIRT553185	hsa-miR-524-5p	PAR-CLIP	21572407
MIRT311710	hsa-miR-491-3p	PAR-CLIP	21572407
MIRT464835	hsa-miR-6808-5p	PAR-CLIP	23592263
MIRT464834	hsa-miR-6893-5p	PAR-CLIP	23592263
MIRT464833	hsa-miR-940	PAR-CLIP	23592263
MIRT256415	hsa-miR-302c-3p	PAR-CLIP	23592263
MIRT464832	hsa-miR-520f-3p	PAR-CLIP	23592263
MIRT464831	hsa-miR-1825	PAR-CLIP	23592263
MIRT464830	hsa-miR-1827	PAR-CLIP	23592263
MIRT464829	hsa-miR-6089	PAR-CLIP	23592263
MIRT464828	hsa-miR-214-5p	PAR-CLIP	23592263
MIRT464827	hsa-miR-6811-3p	PAR-CLIP	23592263
MIRT464826	hsa-miR-1251-3p	PAR-CLIP	23592263
MIRT464825	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT464824	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT464823	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT464822	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT464821	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT464820	hsa-miR-6799-5p	PAR-CLIP	23592263
MIRT464819	hsa-miR-6514-3p	PAR-CLIP	23592263
MIRT464818	hsa-miR-30c-1-3p	PAR-CLIP	23592263
MIRT464817	hsa-miR-30c-2-3p	PAR-CLIP	23592263
MIRT464816	hsa-miR-6788-5p	PAR-CLIP	23592263
MIRT464815	hsa-miR-1273h-5p	PAR-CLIP	23592263
MIRT464814	hsa-miR-30b-3p	PAR-CLIP	23592263
MIRT464813	hsa-miR-3689a-3p	PAR-CLIP	23592263
MIRT464812	hsa-miR-3689b-3p	PAR-CLIP	23592263
MIRT464811	hsa-miR-3689c	PAR-CLIP	23592263
MIRT464809	hsa-miR-6779-5p	PAR-CLIP	23592263
MIRT464810	hsa-miR-6780a-5p	PAR-CLIP	23592263
MIRT464808	hsa-miR-450a-1-3p	PAR-CLIP	23592263
MIRT464807	hsa-miR-3122	PAR-CLIP	23592263
MIRT464806	hsa-miR-3913-5p	PAR-CLIP	23592263
MIRT464805	hsa-miR-887-5p	PAR-CLIP	23592263
MIRT464804	hsa-miR-6513-5p	PAR-CLIP	23592263
MIRT697902	hsa-miR-4438	HITS-CLIP	23313552
MIRT553190	hsa-miR-6504-3p	HITS-CLIP	23313552
MIRT697901	hsa-miR-4269	HITS-CLIP	23313552
MIRT697899	hsa-miR-6715b-5p	HITS-CLIP	23313552
MIRT697900	hsa-miR-4740-3p	HITS-CLIP	23313552
MIRT697898	hsa-miR-4722-3p	HITS-CLIP	23313552
MIRT697897	hsa-miR-6727-3p	HITS-CLIP	23313552
MIRT697896	hsa-miR-6747-3p	HITS-CLIP	23313552
MIRT697895	hsa-miR-619-5p	HITS-CLIP	23313552
MIRT697894	hsa-miR-6506-5p	HITS-CLIP	23313552
MIRT697893	hsa-miR-6804-3p	HITS-CLIP	23313552
MIRT697892	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT697891	hsa-miR-4763-5p	HITS-CLIP	23313552
MIRT697889	hsa-miR-5095	HITS-CLIP	23313552
MIRT697890	hsa-miR-7151-3p	HITS-CLIP	23313552
MIRT697888	hsa-miR-4715-3p	HITS-CLIP	23313552
MIRT697887	hsa-miR-5089-5p	HITS-CLIP	23313552
MIRT697886	hsa-miR-3174	HITS-CLIP	23313552
MIRT697885	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT697884	hsa-miR-3190-5p	HITS-CLIP	23313552
MIRT697883	hsa-miR-4524a-3p	HITS-CLIP	23313552
MIRT697882	hsa-miR-4786-5p	HITS-CLIP	23313552
MIRT697881	hsa-miR-769-5p	HITS-CLIP	23313552
MIRT697880	hsa-miR-3926	HITS-CLIP	23313552
MIRT697879	hsa-miR-921	HITS-CLIP	23313552
MIRT697878	hsa-miR-3672	HITS-CLIP	23313552
MIRT697877	hsa-miR-6864-3p	HITS-CLIP	23313552
MIRT697876	hsa-miR-548s	HITS-CLIP	23313552
MIRT553192	hsa-miR-377-3p	PAR-CLIP	21572407
MIRT311711	hsa-miR-3942-5p	PAR-CLIP	21572407
MIRT311713	hsa-miR-4703-5p	PAR-CLIP	21572407
MIRT553191	hsa-miR-5000-5p	PAR-CLIP	21572407
MIRT553190	hsa-miR-6504-3p	PAR-CLIP	21572407
MIRT553189	hsa-miR-1228-3p	PAR-CLIP	21572407
MIRT553188	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT553187	hsa-miR-107	PAR-CLIP	21572407
MIRT553186	hsa-miR-520d-5p	PAR-CLIP	21572407
MIRT553185	hsa-miR-524-5p	PAR-CLIP	21572407
MIRT311710	hsa-miR-491-3p	PAR-CLIP	21572407
MIRT464835	hsa-miR-6808-5p	PAR-CLIP	23592263
MIRT464834	hsa-miR-6893-5p	PAR-CLIP	23592263
MIRT464833	hsa-miR-940	PAR-CLIP	23592263
MIRT256415	hsa-miR-302c-3p	PAR-CLIP	23592263
MIRT464832	hsa-miR-520f-3p	PAR-CLIP	23592263
MIRT464831	hsa-miR-1825	PAR-CLIP	23592263
MIRT464830	hsa-miR-1827	PAR-CLIP	23592263
MIRT464829	hsa-miR-6089	PAR-CLIP	23592263
MIRT464828	hsa-miR-214-5p	PAR-CLIP	23592263
MIRT464827	hsa-miR-6811-3p	PAR-CLIP	23592263
MIRT464826	hsa-miR-1251-3p	PAR-CLIP	23592263
MIRT464825	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT464824	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT464823	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT464822	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT464821	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT464820	hsa-miR-6799-5p	PAR-CLIP	23592263
MIRT464819	hsa-miR-6514-3p	PAR-CLIP	23592263
MIRT464818	hsa-miR-30c-1-3p	PAR-CLIP	23592263
MIRT464817	hsa-miR-30c-2-3p	PAR-CLIP	23592263
MIRT464816	hsa-miR-6788-5p	PAR-CLIP	23592263
MIRT464815	hsa-miR-1273h-5p	PAR-CLIP	23592263
MIRT464814	hsa-miR-30b-3p	PAR-CLIP	23592263
MIRT464813	hsa-miR-3689a-3p	PAR-CLIP	23592263
MIRT464812	hsa-miR-3689b-3p	PAR-CLIP	23592263
MIRT464811	hsa-miR-3689c	PAR-CLIP	23592263
MIRT464809	hsa-miR-6779-5p	PAR-CLIP	23592263
MIRT464810	hsa-miR-6780a-5p	PAR-CLIP	23592263
MIRT464808	hsa-miR-450a-1-3p	PAR-CLIP	23592263
MIRT464807	hsa-miR-3122	PAR-CLIP	23592263
MIRT464806	hsa-miR-3913-5p	PAR-CLIP	23592263
MIRT464805	hsa-miR-887-5p	PAR-CLIP	23592263
MIRT464804	hsa-miR-6513-5p	PAR-CLIP	23592263
MIRT1466966	hsa-miR-103a	CLIP-seq
MIRT1466967	hsa-miR-1184	CLIP-seq
MIRT1466968	hsa-miR-1205	CLIP-seq
MIRT1466969	hsa-miR-1228	CLIP-seq
MIRT1466970	hsa-miR-1245	CLIP-seq
MIRT1466971	hsa-miR-1256	CLIP-seq
MIRT1466972	hsa-miR-1291	CLIP-seq
MIRT1466973	hsa-miR-200b	CLIP-seq
MIRT1466974	hsa-miR-200c	CLIP-seq
MIRT1466975	hsa-miR-203	CLIP-seq
MIRT1466976	hsa-miR-2116	CLIP-seq
MIRT1466977	hsa-miR-214	CLIP-seq
MIRT1466978	hsa-miR-298	CLIP-seq
MIRT1466979	hsa-miR-302a	CLIP-seq
MIRT1466980	hsa-miR-302b	CLIP-seq
MIRT1466981	hsa-miR-302c	CLIP-seq
MIRT1466982	hsa-miR-302d	CLIP-seq
MIRT1466983	hsa-miR-302e	CLIP-seq
MIRT1466984	hsa-miR-3064-5p	CLIP-seq
MIRT1466985	hsa-miR-3121-5p	CLIP-seq
MIRT1466986	hsa-miR-3129-3p	CLIP-seq
MIRT1466987	hsa-miR-3140-3p	CLIP-seq
MIRT1466988	hsa-miR-3152-5p	CLIP-seq
MIRT1466989	hsa-miR-3158-5p	CLIP-seq
MIRT1466990	hsa-miR-3161	CLIP-seq
MIRT1466991	hsa-miR-3163	CLIP-seq
MIRT1466992	hsa-miR-3176	CLIP-seq
MIRT1466993	hsa-miR-3185	CLIP-seq
MIRT1466994	hsa-miR-323-3p	CLIP-seq
MIRT1466995	hsa-miR-3614-5p	CLIP-seq
MIRT1466996	hsa-miR-3619-5p	CLIP-seq
MIRT1466997	hsa-miR-3652	CLIP-seq
MIRT1466998	hsa-miR-3663-5p	CLIP-seq
MIRT1466999	hsa-miR-3674	CLIP-seq
MIRT1467000	hsa-miR-371-5p	CLIP-seq
MIRT1467001	hsa-miR-371b-5p	CLIP-seq
MIRT1467002	hsa-miR-372	CLIP-seq
MIRT1467003	hsa-miR-373	CLIP-seq
MIRT1467004	hsa-miR-377	CLIP-seq
MIRT1467005	hsa-miR-3922-3p	CLIP-seq
MIRT1467006	hsa-miR-3973	CLIP-seq
MIRT1467007	hsa-miR-3978	CLIP-seq
MIRT1467008	hsa-miR-4253	CLIP-seq
MIRT1467009	hsa-miR-4258	CLIP-seq
MIRT1467010	hsa-miR-429	CLIP-seq
MIRT1467011	hsa-miR-4291	CLIP-seq
MIRT1467012	hsa-miR-4317	CLIP-seq
MIRT1467013	hsa-miR-4325	CLIP-seq
MIRT1467014	hsa-miR-4418	CLIP-seq
MIRT1467015	hsa-miR-4430	CLIP-seq
MIRT1467016	hsa-miR-4504	CLIP-seq
MIRT1467017	hsa-miR-4505	CLIP-seq
MIRT1467018	hsa-miR-4528	CLIP-seq
MIRT1467019	hsa-miR-455-5p	CLIP-seq
MIRT1467020	hsa-miR-4639-5p	CLIP-seq
MIRT1467021	hsa-miR-4670-3p	CLIP-seq
MIRT1467022	hsa-miR-4677-5p	CLIP-seq
MIRT1467023	hsa-miR-4690-5p	CLIP-seq
MIRT1467024	hsa-miR-4698	CLIP-seq
MIRT1467025	hsa-miR-4709-3p	CLIP-seq
MIRT1467026	hsa-miR-4714-3p	CLIP-seq
MIRT1467027	hsa-miR-4720-5p	CLIP-seq
MIRT1467028	hsa-miR-4731-3p	CLIP-seq
MIRT1467029	hsa-miR-4760-3p	CLIP-seq
MIRT1467030	hsa-miR-4774-3p	CLIP-seq
MIRT1467031	hsa-miR-4778-5p	CLIP-seq
MIRT1467032	hsa-miR-4789-5p	CLIP-seq
MIRT1467033	hsa-miR-4799-3p	CLIP-seq
MIRT1467034	hsa-miR-4801	CLIP-seq
MIRT1467035	hsa-miR-486-3p	CLIP-seq
MIRT1467036	hsa-miR-500a	CLIP-seq
MIRT1467037	hsa-miR-502-5p	CLIP-seq
MIRT1467038	hsa-miR-509-3-5p	CLIP-seq
MIRT1467039	hsa-miR-509-5p	CLIP-seq
MIRT1467040	hsa-miR-512-5p	CLIP-seq
MIRT1467041	hsa-miR-513c	CLIP-seq
MIRT1467042	hsa-miR-514b-5p	CLIP-seq
MIRT1467043	hsa-miR-515-5p	CLIP-seq
MIRT1467044	hsa-miR-519a	CLIP-seq
MIRT1467045	hsa-miR-519b-3p	CLIP-seq
MIRT1467046	hsa-miR-519c-3p	CLIP-seq
MIRT1467047	hsa-miR-520a-3p	CLIP-seq
MIRT1467048	hsa-miR-520b	CLIP-seq
MIRT1467049	hsa-miR-520c-3p	CLIP-seq
MIRT1467050	hsa-miR-520d-3p	CLIP-seq
MIRT1467051	hsa-miR-520e	CLIP-seq
MIRT1467052	hsa-miR-520f	CLIP-seq
MIRT1467053	hsa-miR-520g	CLIP-seq
MIRT1467054	hsa-miR-520h	CLIP-seq
MIRT1467055	hsa-miR-544	CLIP-seq
MIRT1467056	hsa-miR-548aa	CLIP-seq
MIRT1467057	hsa-miR-548k	CLIP-seq
MIRT1467058	hsa-miR-548n	CLIP-seq
MIRT1467059	hsa-miR-550a	CLIP-seq
MIRT1467060	hsa-miR-570	CLIP-seq
MIRT1467061	hsa-miR-617	CLIP-seq
MIRT1467062	hsa-miR-649	CLIP-seq
MIRT1467063	hsa-miR-656	CLIP-seq
MIRT1467064	hsa-miR-664	CLIP-seq
MIRT1467065	hsa-miR-761	CLIP-seq
MIRT1467066	hsa-miR-890	CLIP-seq
MIRT1467067	hsa-miR-891b	CLIP-seq
MIRT1467068	hsa-miR-922	CLIP-seq
MIRT1555299	hsa-miR-3614-3p	CLIP-seq
MIRT1555300	hsa-miR-4263	CLIP-seq
MIRT1555301	hsa-miR-4282	CLIP-seq
MIRT1555302	hsa-miR-4712-3p	CLIP-seq
MIRT1467028	hsa-miR-4731-3p	CLIP-seq
MIRT1467032	hsa-miR-4789-5p	CLIP-seq
MIRT1467034	hsa-miR-4801	CLIP-seq
MIRT1555303	hsa-miR-576-5p	CLIP-seq
MIRT2140340	hsa-miR-106a	CLIP-seq
MIRT2140341	hsa-miR-106b	CLIP-seq
MIRT2140342	hsa-miR-122	CLIP-seq
MIRT2140343	hsa-miR-124	CLIP-seq
MIRT2140344	hsa-miR-130a	CLIP-seq
MIRT2140345	hsa-miR-130b	CLIP-seq
MIRT2140346	hsa-miR-137	CLIP-seq
MIRT2140347	hsa-miR-150	CLIP-seq
MIRT2140348	hsa-miR-17	CLIP-seq
MIRT2140349	hsa-miR-199a-5p	CLIP-seq
MIRT2140350	hsa-miR-199b-5p	CLIP-seq
MIRT2140351	hsa-miR-20a	CLIP-seq
MIRT2140352	hsa-miR-20b	CLIP-seq
MIRT2140353	hsa-miR-301a	CLIP-seq
MIRT2140354	hsa-miR-301b	CLIP-seq
MIRT1466979	hsa-miR-302a	CLIP-seq
MIRT1466980	hsa-miR-302b	CLIP-seq
MIRT1466981	hsa-miR-302c	CLIP-seq
MIRT1466982	hsa-miR-302d	CLIP-seq
MIRT1466983	hsa-miR-302e	CLIP-seq
MIRT2140355	hsa-miR-3135b	CLIP-seq
MIRT2140356	hsa-miR-3149	CLIP-seq
MIRT1466988	hsa-miR-3152-5p	CLIP-seq
MIRT2140357	hsa-miR-3194-3p	CLIP-seq
MIRT2140358	hsa-miR-3199	CLIP-seq
MIRT2140359	hsa-miR-34b	CLIP-seq
MIRT2140360	hsa-miR-3613-3p	CLIP-seq
MIRT1466997	hsa-miR-3652	CLIP-seq
MIRT2140361	hsa-miR-3666	CLIP-seq
MIRT2140362	hsa-miR-3714	CLIP-seq
MIRT1467002	hsa-miR-372	CLIP-seq
MIRT1467003	hsa-miR-373	CLIP-seq
MIRT2140363	hsa-miR-3910	CLIP-seq
MIRT2140364	hsa-miR-4295	CLIP-seq
MIRT1467015	hsa-miR-4430	CLIP-seq
MIRT2140365	hsa-miR-4452	CLIP-seq
MIRT2140366	hsa-miR-454	CLIP-seq
MIRT2140367	hsa-miR-4731-5p	CLIP-seq
MIRT2140368	hsa-miR-4738-3p	CLIP-seq
MIRT2140369	hsa-miR-4765	CLIP-seq
MIRT1467030	hsa-miR-4774-3p	CLIP-seq
MIRT2140370	hsa-miR-4797-5p	CLIP-seq
MIRT2140371	hsa-miR-506	CLIP-seq
MIRT2140372	hsa-miR-512-3p	CLIP-seq
MIRT2140373	hsa-miR-519d	CLIP-seq
MIRT1467047	hsa-miR-520a-3p	CLIP-seq
MIRT1467048	hsa-miR-520b	CLIP-seq
MIRT1467049	hsa-miR-520c-3p	CLIP-seq
MIRT1467050	hsa-miR-520d-3p	CLIP-seq
MIRT1467051	hsa-miR-520e	CLIP-seq
MIRT1467053	hsa-miR-520g	CLIP-seq
MIRT1467054	hsa-miR-520h	CLIP-seq
MIRT2140374	hsa-miR-552	CLIP-seq
MIRT2140375	hsa-miR-654-3p	CLIP-seq
MIRT1467064	hsa-miR-664	CLIP-seq
MIRT2140376	hsa-miR-888	CLIP-seq
MIRT2140377	hsa-miR-93	CLIP-seq
MIRT1466966	hsa-miR-103a	CLIP-seq
MIRT2140340	hsa-miR-106a	CLIP-seq
MIRT2140341	hsa-miR-106b	CLIP-seq
MIRT1466967	hsa-miR-1184	CLIP-seq
MIRT2140342	hsa-miR-122	CLIP-seq
MIRT1466969	hsa-miR-1228	CLIP-seq
MIRT1466970	hsa-miR-1245	CLIP-seq
MIRT2140344	hsa-miR-130a	CLIP-seq
MIRT2140345	hsa-miR-130b	CLIP-seq
MIRT2361080	hsa-miR-15a	CLIP-seq
MIRT2361081	hsa-miR-15b	CLIP-seq
MIRT2361082	hsa-miR-16	CLIP-seq
MIRT2140348	hsa-miR-17	CLIP-seq
MIRT2361083	hsa-miR-195	CLIP-seq
MIRT2361084	hsa-miR-2054	CLIP-seq
MIRT2140351	hsa-miR-20a	CLIP-seq
MIRT2140352	hsa-miR-20b	CLIP-seq
MIRT2140353	hsa-miR-301a	CLIP-seq
MIRT2140354	hsa-miR-301b	CLIP-seq
MIRT1466979	hsa-miR-302a	CLIP-seq
MIRT1466980	hsa-miR-302b	CLIP-seq
MIRT1466981	hsa-miR-302c	CLIP-seq
MIRT1466982	hsa-miR-302d	CLIP-seq
MIRT1466983	hsa-miR-302e	CLIP-seq
MIRT2140355	hsa-miR-3135b	CLIP-seq
MIRT1466987	hsa-miR-3140-3p	CLIP-seq
MIRT1466993	hsa-miR-3185	CLIP-seq
MIRT1466994	hsa-miR-323-3p	CLIP-seq
MIRT2140359	hsa-miR-34b	CLIP-seq
MIRT2361085	hsa-miR-3609	CLIP-seq
MIRT1466997	hsa-miR-3652	CLIP-seq
MIRT2140361	hsa-miR-3666	CLIP-seq
MIRT1467000	hsa-miR-371-5p	CLIP-seq
MIRT1467001	hsa-miR-371b-5p	CLIP-seq
MIRT1467002	hsa-miR-372	CLIP-seq
MIRT1467003	hsa-miR-373	CLIP-seq
MIRT1467004	hsa-miR-377	CLIP-seq
MIRT2361086	hsa-miR-380	CLIP-seq
MIRT1467006	hsa-miR-3973	CLIP-seq
MIRT2361087	hsa-miR-424	CLIP-seq
MIRT2361088	hsa-miR-4277	CLIP-seq
MIRT1555301	hsa-miR-4282	CLIP-seq
MIRT2140364	hsa-miR-4295	CLIP-seq
MIRT1467014	hsa-miR-4418	CLIP-seq
MIRT1467015	hsa-miR-4430	CLIP-seq
MIRT2140366	hsa-miR-454	CLIP-seq
MIRT2361089	hsa-miR-4666-5p	CLIP-seq
MIRT2361090	hsa-miR-4711-5p	CLIP-seq
MIRT1467026	hsa-miR-4714-3p	CLIP-seq
MIRT1467028	hsa-miR-4731-3p	CLIP-seq
MIRT1467032	hsa-miR-4789-5p	CLIP-seq
MIRT2361091	hsa-miR-4796-3p	CLIP-seq
MIRT2140370	hsa-miR-4797-5p	CLIP-seq
MIRT1467034	hsa-miR-4801	CLIP-seq
MIRT2361092	hsa-miR-497	CLIP-seq
MIRT1467038	hsa-miR-509-3-5p	CLIP-seq
MIRT1467039	hsa-miR-509-5p	CLIP-seq
MIRT2140373	hsa-miR-519d	CLIP-seq
MIRT1467047	hsa-miR-520a-3p	CLIP-seq
MIRT1467048	hsa-miR-520b	CLIP-seq
MIRT1467049	hsa-miR-520c-3p	CLIP-seq
MIRT1467050	hsa-miR-520d-3p	CLIP-seq
MIRT1467051	hsa-miR-520e	CLIP-seq
MIRT1467053	hsa-miR-520g	CLIP-seq
MIRT1467054	hsa-miR-520h	CLIP-seq
MIRT2361093	hsa-miR-545	CLIP-seq
MIRT2361094	hsa-miR-548ah	CLIP-seq
MIRT1467057	hsa-miR-548k	CLIP-seq
MIRT2361095	hsa-miR-548m	CLIP-seq
MIRT1467058	hsa-miR-548n	CLIP-seq
MIRT2361096	hsa-miR-548p	CLIP-seq
MIRT2361097	hsa-miR-586	CLIP-seq
MIRT1467064	hsa-miR-664	CLIP-seq
MIRT2140377	hsa-miR-93	CLIP-seq
MIRT1466967	hsa-miR-1184	CLIP-seq
MIRT1466967	hsa-miR-1184	CLIP-seq
MIRT2140342	hsa-miR-122	CLIP-seq
MIRT2654873	hsa-miR-1227	CLIP-seq
MIRT1466969	hsa-miR-1228	CLIP-seq
MIRT2654874	hsa-miR-1252	CLIP-seq
MIRT2654875	hsa-miR-1270	CLIP-seq
MIRT2140344	hsa-miR-130a	CLIP-seq
MIRT2140345	hsa-miR-130b	CLIP-seq
MIRT2140346	hsa-miR-137	CLIP-seq
MIRT2654876	hsa-miR-142-5p	CLIP-seq
MIRT2654877	hsa-miR-181a	CLIP-seq
MIRT2654878	hsa-miR-181b	CLIP-seq
MIRT2654879	hsa-miR-181c	CLIP-seq
MIRT2654880	hsa-miR-181d	CLIP-seq
MIRT1466976	hsa-miR-2116	CLIP-seq
MIRT2140353	hsa-miR-301a	CLIP-seq
MIRT2140354	hsa-miR-301b	CLIP-seq
MIRT1466986	hsa-miR-3129-3p	CLIP-seq
MIRT2140355	hsa-miR-3135b	CLIP-seq
MIRT1466987	hsa-miR-3140-3p	CLIP-seq
MIRT1466990	hsa-miR-3161	CLIP-seq
MIRT1466991	hsa-miR-3163	CLIP-seq
MIRT2140357	hsa-miR-3194-3p	CLIP-seq
MIRT1466994	hsa-miR-323-3p	CLIP-seq
MIRT1555299	hsa-miR-3614-3p	CLIP-seq
MIRT1466997	hsa-miR-3652	CLIP-seq
MIRT2140361	hsa-miR-3666	CLIP-seq
MIRT1466999	hsa-miR-3674	CLIP-seq
MIRT2654881	hsa-miR-374a	CLIP-seq
MIRT2654882	hsa-miR-374b	CLIP-seq
MIRT2654883	hsa-miR-4252	CLIP-seq
MIRT2654884	hsa-miR-4262	CLIP-seq
MIRT1555300	hsa-miR-4263	CLIP-seq
MIRT1555301	hsa-miR-4282	CLIP-seq
MIRT2140364	hsa-miR-4295	CLIP-seq
MIRT1467015	hsa-miR-4430	CLIP-seq
MIRT2654885	hsa-miR-4531	CLIP-seq
MIRT2140366	hsa-miR-454	CLIP-seq
MIRT1467022	hsa-miR-4677-5p	CLIP-seq
MIRT2654886	hsa-miR-4683	CLIP-seq
MIRT1467024	hsa-miR-4698	CLIP-seq
MIRT1467025	hsa-miR-4709-3p	CLIP-seq
MIRT1555302	hsa-miR-4712-3p	CLIP-seq
MIRT1467028	hsa-miR-4731-3p	CLIP-seq
MIRT2654887	hsa-miR-4735-5p	CLIP-seq
MIRT2140368	hsa-miR-4738-3p	CLIP-seq
MIRT2654888	hsa-miR-4742-5p	CLIP-seq
MIRT2654889	hsa-miR-4775	CLIP-seq
MIRT1467032	hsa-miR-4789-5p	CLIP-seq
MIRT2654890	hsa-miR-4799-5p	CLIP-seq
MIRT1467034	hsa-miR-4801	CLIP-seq
MIRT1467037	hsa-miR-502-5p	CLIP-seq
MIRT1467055	hsa-miR-544	CLIP-seq
MIRT2654891	hsa-miR-548g	CLIP-seq
MIRT1467057	hsa-miR-548k	CLIP-seq
MIRT1467058	hsa-miR-548n	CLIP-seq
MIRT2654892	hsa-miR-561	CLIP-seq
MIRT1555303	hsa-miR-576-5p	CLIP-seq
MIRT2654893	hsa-miR-590-3p	CLIP-seq
MIRT1467061	hsa-miR-617	CLIP-seq
MIRT2654894	hsa-miR-620	CLIP-seq
MIRT1466967	hsa-miR-1184	CLIP-seq
MIRT2140342	hsa-miR-122	CLIP-seq
MIRT2654873	hsa-miR-1227	CLIP-seq
MIRT2654875	hsa-miR-1270	CLIP-seq
MIRT2140344	hsa-miR-130a	CLIP-seq
MIRT2140345	hsa-miR-130b	CLIP-seq
MIRT2140346	hsa-miR-137	CLIP-seq
MIRT2654876	hsa-miR-142-5p	CLIP-seq
MIRT2654877	hsa-miR-181a	CLIP-seq
MIRT2654878	hsa-miR-181b	CLIP-seq
MIRT2654879	hsa-miR-181c	CLIP-seq
MIRT2654880	hsa-miR-181d	CLIP-seq
MIRT2140353	hsa-miR-301a	CLIP-seq
MIRT2140354	hsa-miR-301b	CLIP-seq
MIRT1466986	hsa-miR-3129-3p	CLIP-seq
MIRT2140355	hsa-miR-3135b	CLIP-seq
MIRT1466987	hsa-miR-3140-3p	CLIP-seq
MIRT1466990	hsa-miR-3161	CLIP-seq
MIRT1466991	hsa-miR-3163	CLIP-seq
MIRT2140357	hsa-miR-3194-3p	CLIP-seq
MIRT2140359	hsa-miR-34b	CLIP-seq
MIRT1555299	hsa-miR-3614-3p	CLIP-seq
MIRT1466997	hsa-miR-3652	CLIP-seq
MIRT2140361	hsa-miR-3666	CLIP-seq
MIRT1466999	hsa-miR-3674	CLIP-seq
MIRT2654881	hsa-miR-374a	CLIP-seq
MIRT2654882	hsa-miR-374b	CLIP-seq
MIRT2654883	hsa-miR-4252	CLIP-seq
MIRT2654884	hsa-miR-4262	CLIP-seq
MIRT1555300	hsa-miR-4263	CLIP-seq
MIRT1555301	hsa-miR-4282	CLIP-seq
MIRT2140364	hsa-miR-4295	CLIP-seq
MIRT1467014	hsa-miR-4418	CLIP-seq
MIRT1467015	hsa-miR-4430	CLIP-seq
MIRT2654885	hsa-miR-4531	CLIP-seq
MIRT2140366	hsa-miR-454	CLIP-seq
MIRT2654886	hsa-miR-4683	CLIP-seq
MIRT1467024	hsa-miR-4698	CLIP-seq
MIRT1467025	hsa-miR-4709-3p	CLIP-seq
MIRT1555302	hsa-miR-4712-3p	CLIP-seq
MIRT1467026	hsa-miR-4714-3p	CLIP-seq
MIRT1467028	hsa-miR-4731-3p	CLIP-seq
MIRT2654887	hsa-miR-4735-5p	CLIP-seq
MIRT2140368	hsa-miR-4738-3p	CLIP-seq
MIRT2654888	hsa-miR-4742-5p	CLIP-seq
MIRT2654889	hsa-miR-4775	CLIP-seq
MIRT1467032	hsa-miR-4789-5p	CLIP-seq
MIRT2654890	hsa-miR-4799-5p	CLIP-seq
MIRT1467034	hsa-miR-4801	CLIP-seq
MIRT1467037	hsa-miR-502-5p	CLIP-seq
MIRT1467038	hsa-miR-509-3-5p	CLIP-seq
MIRT1467039	hsa-miR-509-5p	CLIP-seq
MIRT2654892	hsa-miR-561	CLIP-seq
MIRT1555303	hsa-miR-576-5p	CLIP-seq
MIRT2654893	hsa-miR-590-3p	CLIP-seq
MIRT1467061	hsa-miR-617	CLIP-seq
MIRT2654894	hsa-miR-620	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0000209	Process	Protein polyubiquitination	IBA
GO:0000785	Component	Chromatin	IEA
GO:0000785	Component	Chromatin	ISS
GO:0001701	Process	In utero embryonic development	IEA
GO:0001741	Component	XY body	IEA
GO:0004842	Function	Ubiquitin-protein transferase activity	IDA	10373550, 19123975, 20061386
GO:0004842	Function	Ubiquitin-protein transferase activity	IMP	18339854
GO:0005515	Function	Protein binding	IPI	12776193, 16169070, 19549727, 20080676, 21422291, 28514442, 32296183, 33961781
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IDA	18339854
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005657	Component	Replication fork	IDA	18363965
GO:0005737	Component	Cytoplasm	IDA	18339854
GO:0005886	Component	Plasma membrane	IEA
GO:0006281	Process	DNA repair	IBA
GO:0006281	Process	DNA repair	IEA
GO:0006281	Process	DNA repair	IGI	1717990
GO:0006301	Process	Postreplication repair	IDA	14981545
GO:0006301	Process	Postreplication repair	NAS	1559696
GO:0006325	Process	Chromatin organization	IEA
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IDA	10373550
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	NAS	1559696
GO:0006915	Process	Apoptotic process	IEA
GO:0006974	Process	DNA damage response	IDA	14981545
GO:0006974	Process	DNA damage response	IEA
GO:0007283	Process	Spermatogenesis	TAS	18497339
GO:0007288	Process	Sperm axoneme assembly	IEA
GO:0009410	Process	Response to xenobiotic stimulus	IDA	14981545
GO:0009411	Process	Response to UV	IGI	1717990
GO:0010845	Process	Positive regulation of reciprocal meiotic recombination	IEA
GO:0016020	Component	Membrane	IEA
GO:0016567	Process	Protein ubiquitination	IDA	10373550, 19123975
GO:0016567	Process	Protein ubiquitination	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0019787	Function	Ubiquitin-like protein transferase activity	IEA
GO:0031625	Function	Ubiquitin protein ligase binding	IEA
GO:0031625	Function	Ubiquitin protein ligase binding	IPI	10908344, 18363965
GO:0033503	Component	HULC complex	IBA
GO:0033503	Component	HULC complex	IDA	19410543
GO:0033503	Component	HULC complex	IEA
GO:0035234	Process	Ectopic germ cell programmed cell death	IEA
GO:0043066	Process	Negative regulation of apoptotic process	IEA
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IBA
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IDA	10373550
GO:0045141	Process	Meiotic telomere clustering	IEA
GO:0050821	Process	Protein stabilization	IMP	18339854
GO:0051026	Process	Chiasma assembly	IEA
GO:0051093	Process	Negative regulation of developmental process	IEA
GO:0051865	Process	Protein autoubiquitination	IDA	19123975
GO:0061631	Function	Ubiquitin conjugating enzyme activity	IBA
GO:0061631	Function	Ubiquitin conjugating enzyme activity	IDA	38182926
GO:0061631	Function	Ubiquitin conjugating enzyme activity	IEA
GO:0070193	Process	Synaptonemal complex organization	IEA
GO:0070534	Process	Protein K63-linked ubiquitination	IDA	20061386
GO:0070936	Process	Protein K48-linked ubiquitination	IDA	20061386
GO:0070936	Process	Protein K48-linked ubiquitination	IEA
GO:0070979	Process	Protein K11-linked ubiquitination	IDA	20061386
GO:0070979	Process	Protein K11-linked ubiquitination	IEA
GO:0090263	Process	Positive regulation of canonical Wnt signaling pathway	IEA
GO:0090263	Process	Positive regulation of canonical Wnt signaling pathway	ISS
GO:1901874	Process	Negative regulation of post-translational protein modification	IEA
GO:2000242	Process	Negative regulation of reproductive process	IEA

Other IDs

• MIM: 179095
• HGNC: 12473
• e!Ensembl: ENSG00000119048

Protein

• UniProt ID: P63146
• Protein name: Ubiquitin-conjugating enzyme E2 B (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme B) (RAD6 homolog B) (HR6B) (hHR6B) (Ubiquitin carrier protein B) (Ubiquitin-conjugating enzyme E2-17 kDa) (Ubiquitin-protein ligase B)
• Protein function: E2 ubiquitin-conjugating enzyme that accepts ubiquitin from the ubiquitin-activating enzyme E1 and transfers it to a E3 ubiquitin-protein ligase (PubMed:16337599, PubMed:17108083, PubMed:17130289, PubMed:1717990, PubMed:20061386). In vitro catal
• PDB: 1JAS, 2Y4W, 2YB6, 2YBF
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00179	UQ_con	8 → 145	Ubiquitin-conjugating enzyme	Domain

• Sequence:

  MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFS
  EEYPNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
  PANSQAAQLYQENKREYEKRVSAIVEQSWNDS

• Sequence length: 152

Pathways

KEGG:

Ubiquitin mediated proteolysis

Reactome:

Recognition of DNA damage by PCNA-containing replication complex
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
E3 ubiquitin ligases ubiquitinate target proteins
Antigen processing: Ubiquitination & Proteasome degradation

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
SYSTEMIC LUPUS ERYTHEMATOSUS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
UBE2B-related disorder	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Autoimmune thyroiditis	Autoimmune Thyroiditis	BEFREE	27860532		★☆☆☆☆ Found in Text Mining only
Azoospermia	Azoospermia	BEFREE	26223869		★☆☆☆☆ Found in Text Mining only
Azoospermia	Azoospermia	Pubtator	26223869	Associate	★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	17050667, 22705350		★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	17050667	Stimulate	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	22705350	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	BEFREE	8386138		★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	29180379	Associate	★☆☆☆☆ Found in Text Mining only
cervical cancer	Cervical Cancer	BEFREE	14709162, 16454648		★☆☆☆☆ Found in Text Mining only
Cervical Intraepithelial Neoplasia	Cervical Intraepithelial Neoplasia	BEFREE	10859389, 11308254, 9099962		★☆☆☆☆ Found in Text Mining only
Cervix carcinoma	Cervix carcinoma	BEFREE	14709162, 14871818, 16454648, 20530671, 30008422, 8389903		★☆☆☆☆ Found in Text Mining only
Congenital chromosomal disease	Congenital Chromosomal Disease	BEFREE	11040943		★☆☆☆☆ Found in Text Mining only
Cutaneous Melanoma	Melanoma	BEFREE	31683936		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	22721429		★☆☆☆☆ Found in Text Mining only
Epidermodysplasia Verruciformis	Epidermodysplasia Verruciformis	BEFREE	29563902		★☆☆☆☆ Found in Text Mining only
Fanconi Anemia	Fanconi Anemia	BEFREE	31639439		★☆☆☆☆ Found in Text Mining only
Fanconi Anemia	Fanconi anemia	Pubtator	31639439	Associate	★☆☆☆☆ Found in Text Mining only
FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder)	Anemia	BEFREE	31639439		★☆☆☆☆ Found in Text Mining only
Hashimoto Disease	Hashimoto Disease	BEFREE	27860532		★☆☆☆☆ Found in Text Mining only
Hyperplasia	Hyperplasia	Pubtator	17050667	Stimulate	★☆☆☆☆ Found in Text Mining only
Hypoxia	Hypoxia	Pubtator	29180379	Associate	★☆☆☆☆ Found in Text Mining only
Infertility Male	Male infertility	Pubtator	18497339	Associate	★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	10583438		★☆☆☆☆ Found in Text Mining only
Liver neoplasms	Liver neoplasms	BEFREE	10583438		★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	BEFREE	11739181		★☆☆☆☆ Found in Text Mining only
Lymphoproliferative Disorders	Lymphoproliferative Disorder	BEFREE	11739181, 31755827		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	17050667, 22705350		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of skin	Skin cancer	BEFREE	29563902, 9123827		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	1651587		★☆☆☆☆ Found in Text Mining only
Malignant tumor of cervix	Cervical Tumor	BEFREE	14709162, 16454648		★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	LHGDN	17050667, 18339854		★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	BEFREE	31683936		★☆☆☆☆ Found in Text Mining only
Melanoma	Melanoma	Pubtator	31683936	Associate	★☆☆☆☆ Found in Text Mining only
Melanoma Cutaneous Malignant	Melanoma	Pubtator	31683936	Associate	★☆☆☆☆ Found in Text Mining only
Mild cognitive disorder	Cognitive disorder	BEFREE	31305452		★☆☆☆☆ Found in Text Mining only
Nasopharyngeal carcinoma	Nasopharyngeal Carcinoma	BEFREE	30449727		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	10999461, 19390235, 30595560, 9099962		★☆☆☆☆ Found in Text Mining only
Oligospermia	Oligospermia	BEFREE	23378580		★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	21347333	Associate	★☆☆☆☆ Found in Text Mining only
Papilloma	Papilloma	BEFREE	10999461, 16257560, 2828035		★☆☆☆☆ Found in Text Mining only
Retinoblastoma	Retinoblastoma	BEFREE	17182682		★☆☆☆☆ Found in Text Mining only
Skin lesion	Skin Lesion	BEFREE	29563902		★☆☆☆☆ Found in Text Mining only
Skin Neoplasms	Skin Neoplasms	BEFREE	18401427		★☆☆☆☆ Found in Text Mining only
Thyroiditis Autoimmune	Thyroiditis	Pubtator	27860532	Stimulate	★☆☆☆☆ Found in Text Mining only
Triple Negative Breast Neoplasms	Triple Negative Breast Neoplasms	BEFREE	31639439		★☆☆☆☆ Found in Text Mining only
Triple Negative Breast Neoplasms	Triple negative breast cancer	Pubtator	31639439	Associate	★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Uterine neoplasm	Pubtator	2828035	Associate	★☆☆☆☆ Found in Text Mining only