NUTM2B (NUT family member 2B)

Gene

• Entrez ID: 729262
• Gene name: NUT family member 2B
• Gene symbol: NUTM2B
• Synonyms (NCBI Gene): FAM22B, bA119F19.1
• Chromosome: 10
• Chromosome location: 10q22.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT017142	hsa-miR-335-5p	Microarray	18185580

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: A6NNL0
• Protein name: NUT family member 2B
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12881	NUT	136 → 875	NUT protein	Family

• Sequence:

  MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAEALHRTSPTPNSCP
  LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQP
  EGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST
  FPSTPLVTEQDGCGPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG
  VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP
  WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL
  IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ
  WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARR
  PPPRPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK
  QREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF
  LALSQDLEQEEGLTLAQLVEKRLPPLKEKQHARAAPSRGTARLDSSSSKFAAGQGAERDV
  PDPQQGVGMETCPPQMTARDSQGRGRAHTGMARSEDSVVLLGCQDSPGLRAAWPTSPPQD
  HRPTCPGVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGSQHKLLPWWLPQSP
  VPASGLLSPEKWGPQGTHQSPSAERRGLNLAPSPANKAKKRPLFGSLSPAEKTPYPGPGL
  RVSGEQSLTWGLGGPSQSQKRKGDPLVSRKEKKQHCSQ

• Sequence length: 878

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
CLEAR CELL SARCOMA OF KIDNEY	—	Orphanet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ENDOMETRIAL STROMAL SARCOMA	—	Orphanet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Oculopharyngeal myopathy with leukoencephalopathy 1	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Breast Neoplasms	Breast neoplasm	Pubtator	31575382	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	Pubtator	30789359	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	35778520	Associate	★☆☆☆☆ Found in Text Mining only
Clear cell sarcoma of kidney	Sarcoma Of Kidney	BEFREE	22294382, 26493387, 26542179, 28440018		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Clear cell sarcoma of kidney	Sarcoma Of Kidney	ORPHANET_DG	22294382		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Clear cell sarcoma of kidney	Sarcoma Of Kidney	Orphanet			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Desmoplastic Small Round Cell Tumor	Desmoplastic small round cell tumor	Pubtator	27428733	Associate	★☆☆☆☆ Found in Text Mining only
Endometrial Stromal Sarcoma	Endometrial Stromal Sarcoma	ORPHANET_DG	22223660, 25299308		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Endometrial Stromal Sarcoma	Endometrial Stromal Sarcoma	BEFREE	23159154, 24125656		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Endometrial stromal sarcoma	Endometrial Stromal Sarcoma	Orphanet			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Leiomyosarcoma	Leiomyosarcoma	Pubtator	28288693	Associate	★☆☆☆☆ Found in Text Mining only
Leiomyosarcoma, Epithelioid	Leiomyosarcoma	BEFREE	28288693		★☆☆☆☆ Found in Text Mining only
Liposarcoma Myxoid	Liposarcoma	Pubtator	26945340, 32372022	Associate	★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	26158413, 28288693		★☆☆☆☆ Found in Text Mining only
Sarcoma	Sarcoma	Pubtator	37634866	Associate	★☆☆☆☆ Found in Text Mining only
Sarcoma Clear Cell	Sarcoma	Pubtator	26945340, 32372022	Associate	★☆☆☆☆ Found in Text Mining only
Sarcoma Endometrial Stromal	Endometrial stromal sarcoma	Pubtator	22223660, 23599159, 24186140, 28390819, 33077922, 35545369, 36731460	Associate	★☆☆☆☆ Found in Text Mining only