GPR137B (G protein-coupled receptor 137B)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 7107 |
| Gene name | G protein-coupled receptor 137B |
| Gene symbol | GPR137B |
| Synonyms (NCBI Gene) |
TM7SF1
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| Chromosome | 1 |
| Chromosome location | 1q42.3 |
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miRNA
miRNA information provided by mirtarbase database.
396
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
20
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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O60478 | |
| Protein name | Integral membrane protein GPR137B (Transmembrane 7 superfamily member 1 protein) | |
| Protein function | Lysosomal integral membrane protein that regulates the localization and activity of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids (PubMed:31036939). Interacts with Rag GTPases and | |
| Family and domains | ||
| Tissue specificity | TISSUE SPECIFICITY: Expressed in kidney, heart, brain and placenta. {ECO:0000269|PubMed:9521871}. | |
| Sequence |
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| Sequence length | 399 | |
| Interactions | View interactions | |
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
3
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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