Gene Gene information from NCBI Gene database.
Entrez ID 7070
Gene name Thy-1 cell surface antigen
Gene symbol THY1
Synonyms (NCBI Gene)
CD90CDw90
Chromosome 11
Chromosome location 11q23.3
Summary This gene encodes a cell surface glycoprotein and member of the immunoglobulin superfamily of proteins. The encoded protein is involved in cell adhesion and cell communication in numerous cell types, but particularly in cells of the immune and nervous sys
miRNA miRNA information provided by mirtarbase database.
545
miRTarBase ID miRNA Experiments Reference
MIRT024103 hsa-miR-1-3p Proteomics;Microarray 18668037
MIRT490393 hsa-miR-139-3p PAR-CLIP 20371350
MIRT490394 hsa-miR-4781-5p PAR-CLIP 20371350
MIRT490393 hsa-miR-139-3p PAR-CLIP 20371350
MIRT490392 hsa-miR-1228-5p PAR-CLIP 20371350
Transcription factors Transcription factors information provided by TRRUST V2 database.
1
Transcription factor Regulation Reference
POU5F1 Activation 17068183
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
69
GO ID Ontology Definition Evidence Reference
GO:0001525 Process Angiogenesis IEA
GO:0001525 Process Angiogenesis ISS
GO:0001952 Process Regulation of cell-matrix adhesion IMP 9749990
GO:0002682 Process Regulation of immune system process IEA
GO:0002693 Process Positive regulation of cellular extravasation IDA 15004192
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
188230 11801 ENSG00000154096
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P04216
Protein name Thy-1 membrane glycoprotein (CDw90) (Thy-1 antigen) (CD antigen CD90)
Protein function May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00047 ig 21 119 Immunoglobulin domain Domain
Sequence
Sequence length 161
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Leukocyte transendothelial migration   Post-translational modification: synthesis of GPI-anchored proteins
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
CARCINOMA, HEPATOCELLULAR CTD
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Acute intermittent porphyria Intermittent Porphyria BEFREE 20303356
★☆☆☆☆
Found in Text Mining only
Acute leukemia Leukemia BEFREE 7540889
★☆☆☆☆
Found in Text Mining only
Acute lymphocytic leukemia Lymphocytic Leukemia BEFREE 10557051
★☆☆☆☆
Found in Text Mining only
Adenocarcinoma Adenocarcinoma BEFREE 27761727
★☆☆☆☆
Found in Text Mining only
Adenocarcinoma of lung (disorder) Lung adenocarcinoma BEFREE 28744021
★☆☆☆☆
Found in Text Mining only
Alveolitis Extrinsic Allergic Extrinsic allergic alveolitis Pubtator 27792269 Inhibit
★☆☆☆☆
Found in Text Mining only
Alzheimer Disease Alzheimer disease Pubtator 25040401, 34556089 Associate
★☆☆☆☆
Found in Text Mining only
Ameloblastoma Ameloblastoma Pubtator 27737362 Associate
★☆☆☆☆
Found in Text Mining only
Amyotrophic Lateral Sclerosis Amyotrophic Lateral Sclerosis BEFREE 16566922, 20807312, 22047141, 28100513
★☆☆☆☆
Found in Text Mining only
Anaplasia Anaplasia BEFREE 21735473
★☆☆☆☆
Found in Text Mining only