Gene Gene information from NCBI Gene database.
Entrez ID 6990
Gene name Dynein light chain Tctex-type 3
Gene symbol DYNLT3
Synonyms (NCBI Gene)
RP3TCTE1LTCTEX1L
Chromosome X
Chromosome location Xp11.4
Summary This gene encodes a member of a subclass of dynein light chains. The encoded protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex. This protein may be important for binding dynein to specific cargos inc
miRNA miRNA information provided by mirtarbase database.
392
miRTarBase ID miRNA Experiments Reference
MIRT727832 hsa-miR-30a-5p HITS-CLIP 22473208
MIRT727831 hsa-miR-30b-5p HITS-CLIP 22473208
MIRT727830 hsa-miR-30c-5p HITS-CLIP 22473208
MIRT727828 hsa-miR-30d-5p HITS-CLIP 22473208
MIRT727829 hsa-miR-30e-5p HITS-CLIP 22473208
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
23
GO ID Ontology Definition Evidence Reference
GO:0000775 Component Chromosome, centromeric region IEA
GO:0000776 Component Kinetochore IDA 17289665
GO:0000776 Component Kinetochore IEA
GO:0005515 Function Protein binding IPI 16189514, 25416956, 27173435, 31515488, 32296183, 33961781, 35271311
GO:0005634 Component Nucleus IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
300302 11694 ENSG00000165169
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P51808
Protein name Dynein light chain Tctex-type 3 (Protein 91/23) (T-complex-associated testis-expressed 1-like)
Protein function Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03645 Tctex-1 17 113 Tctex-1 family Family
Sequence
Sequence length 116
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG 
  Motor proteins
Salmonella infection
 
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
Nonpapillary renal cell carcinoma Uncertain significance ClinVar
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
UTERINE FIBROID GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Carcinoma Adenoid Cystic Adenoid cystic carcinoma Pubtator 21551254 Associate
★☆☆☆☆
Found in Text Mining only
Carcinoma, Ovarian Epithelial Ovarian Epithelial carcinoma BEFREE 31308737
★☆☆☆☆
Found in Text Mining only
Granulomatous Disease Chronic Granulomatous disease Pubtator 22383943 Associate
★☆☆☆☆
Found in Text Mining only
Malignant neoplasm of ovary Ovarian cancer BEFREE 31308737
★☆☆☆☆
Found in Text Mining only
Muscular Dystrophy Duchenne Duchenne muscular dystrophy Pubtator 17300882 Associate
★☆☆☆☆
Found in Text Mining only
Muscular Dystrophy, Duchenne Duchenne Muscular Dystrophy BEFREE 17300882
★☆☆☆☆
Found in Text Mining only
Myopia Myopia BEFREE 1357178
★☆☆☆☆
Found in Text Mining only
NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2A Night blindness BEFREE 9418727
★☆☆☆☆
Found in Text Mining only
Nyctalopia Nyctalopia BEFREE 1357178
★☆☆☆☆
Found in Text Mining only
ovarian neoplasm Ovarian neoplasm BEFREE 31308737
★☆☆☆☆
Found in Text Mining only