PPAN-P2RY11 (PPAN-P2RY11 readthrough)

Gene

• Entrez ID: 692312
• Gene name: PPAN-P2RY11 readthrough
• Gene symbol: PPAN-P2RY11
• Synonyms (NCBI Gene): BXDC3, P2RY11, P2Y11, PPAN, SSF1, Ssf-1
• Chromosome: 19
• Chromosome location: 19p13.2
• Summary: This locus represents naturally occurring read-through transcription between the adjacent PPAN and P2RY11 genes. Alternative splicing results in two transcript variants, one of which encodes a fusion protein that shares sequence identity with each individ

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT051844	hsa-let-7c-5p	CLASH	23622248
MIRT512604	hsa-miR-1273a	PAR-CLIP	23446348
MIRT453182	hsa-miR-4699-5p	PAR-CLIP	23592263
MIRT453181	hsa-miR-3665	PAR-CLIP	23592263
MIRT453180	hsa-miR-657	PAR-CLIP	23592263
MIRT512604	hsa-miR-1273a	HITS-CLIP	28735896
MIRT512604	hsa-miR-1273a	HITS-CLIP	28735896
MIRT512604	hsa-miR-1273a	PAR-CLIP	23446348
MIRT453182	hsa-miR-4699-5p	PAR-CLIP	23592263
MIRT453181	hsa-miR-3665	PAR-CLIP	23592263
MIRT453180	hsa-miR-657	PAR-CLIP	23592263
MIRT1251187	hsa-miR-1247	CLIP-seq
MIRT1251188	hsa-miR-1273	CLIP-seq
MIRT1251189	hsa-miR-1275	CLIP-seq
MIRT1251190	hsa-miR-23a	CLIP-seq
MIRT1251191	hsa-miR-23b	CLIP-seq
MIRT1251192	hsa-miR-23c	CLIP-seq
MIRT1251193	hsa-miR-3140-3p	CLIP-seq
MIRT1251194	hsa-miR-3202	CLIP-seq
MIRT1251195	hsa-miR-323-3p	CLIP-seq
MIRT1251196	hsa-miR-4260	CLIP-seq
MIRT1251197	hsa-miR-4271	CLIP-seq
MIRT1251198	hsa-miR-4525	CLIP-seq
MIRT1251199	hsa-miR-4665-5p	CLIP-seq
MIRT1251200	hsa-miR-4707-3p	CLIP-seq
MIRT1251201	hsa-miR-4723-5p	CLIP-seq
MIRT1251202	hsa-miR-4725-3p	CLIP-seq
MIRT1251203	hsa-miR-4747-5p	CLIP-seq
MIRT1251204	hsa-miR-4764-5p	CLIP-seq
MIRT1251205	hsa-miR-625	CLIP-seq
MIRT1251190	hsa-miR-23a	CLIP-seq
MIRT1251191	hsa-miR-23b	CLIP-seq
MIRT1251192	hsa-miR-23c	CLIP-seq
MIRT1251195	hsa-miR-323-3p	CLIP-seq
MIRT1251200	hsa-miR-4707-3p	CLIP-seq
MIRT2074124	hsa-miR-1231	CLIP-seq
MIRT2074125	hsa-miR-193a-5p	CLIP-seq
MIRT1251190	hsa-miR-23a	CLIP-seq
MIRT1251191	hsa-miR-23b	CLIP-seq
MIRT1251192	hsa-miR-23c	CLIP-seq
MIRT2074126	hsa-miR-3170	CLIP-seq
MIRT1251195	hsa-miR-323-3p	CLIP-seq
MIRT2074127	hsa-miR-342-5p	CLIP-seq
MIRT2074128	hsa-miR-4313	CLIP-seq
MIRT2074129	hsa-miR-4651	CLIP-seq
MIRT2074130	hsa-miR-4664-5p	CLIP-seq
MIRT2074131	hsa-miR-4667-5p	CLIP-seq
MIRT2074132	hsa-miR-4700-5p	CLIP-seq
MIRT1251200	hsa-miR-4707-3p	CLIP-seq
MIRT2074133	hsa-miR-608	CLIP-seq
MIRT2074134	hsa-miR-615-5p	CLIP-seq
MIRT2074135	hsa-miR-635	CLIP-seq
MIRT2074136	hsa-miR-637	CLIP-seq
MIRT1251190	hsa-miR-23a	CLIP-seq
MIRT1251191	hsa-miR-23b	CLIP-seq
MIRT1251192	hsa-miR-23c	CLIP-seq
MIRT1251195	hsa-miR-323-3p	CLIP-seq
MIRT1251200	hsa-miR-4707-3p	CLIP-seq
MIRT1251190	hsa-miR-23a	CLIP-seq
MIRT1251191	hsa-miR-23b	CLIP-seq
MIRT1251192	hsa-miR-23c	CLIP-seq
MIRT1251195	hsa-miR-323-3p	CLIP-seq
MIRT1251200	hsa-miR-4707-3p	CLIP-seq
MIRT1251188	hsa-miR-1273	CLIP-seq
MIRT2456977	hsa-miR-2277-5p	CLIP-seq
MIRT2456978	hsa-miR-2467-3p	CLIP-seq
MIRT2456979	hsa-miR-4422	CLIP-seq
MIRT2456980	hsa-miR-4639-3p	CLIP-seq
MIRT2074129	hsa-miR-4651	CLIP-seq
MIRT2456981	hsa-miR-4660	CLIP-seq
MIRT2074133	hsa-miR-608	CLIP-seq
MIRT2456982	hsa-miR-646	CLIP-seq
MIRT2456983	hsa-miR-885-3p	CLIP-seq
MIRT1251188	hsa-miR-1273	CLIP-seq
MIRT2456977	hsa-miR-2277-5p	CLIP-seq
MIRT2456978	hsa-miR-2467-3p	CLIP-seq
MIRT2456979	hsa-miR-4422	CLIP-seq
MIRT2456980	hsa-miR-4639-3p	CLIP-seq
MIRT2074129	hsa-miR-4651	CLIP-seq
MIRT2456981	hsa-miR-4660	CLIP-seq
MIRT2074133	hsa-miR-608	CLIP-seq
MIRT2456982	hsa-miR-646	CLIP-seq
MIRT2456983	hsa-miR-885-3p	CLIP-seq
MIRT1251188	hsa-miR-1273	CLIP-seq
MIRT2456977	hsa-miR-2277-5p	CLIP-seq
MIRT2456979	hsa-miR-4422	CLIP-seq
MIRT2456980	hsa-miR-4639-3p	CLIP-seq
MIRT2456981	hsa-miR-4660	CLIP-seq
MIRT2597700	hsa-miR-4684-5p	CLIP-seq
MIRT2456982	hsa-miR-646	CLIP-seq
MIRT1251188	hsa-miR-1273	CLIP-seq
MIRT2688383	hsa-miR-2276	CLIP-seq
MIRT2456977	hsa-miR-2277-5p	CLIP-seq
MIRT2688384	hsa-miR-3064-5p	CLIP-seq
MIRT2688385	hsa-miR-3661	CLIP-seq
MIRT2688386	hsa-miR-3934	CLIP-seq
MIRT2456979	hsa-miR-4422	CLIP-seq
MIRT2456980	hsa-miR-4639-3p	CLIP-seq
MIRT2456981	hsa-miR-4660	CLIP-seq
MIRT2597700	hsa-miR-4684-5p	CLIP-seq
MIRT2688387	hsa-miR-552	CLIP-seq
MIRT2688388	hsa-miR-604	CLIP-seq
MIRT2688389	hsa-miR-631	CLIP-seq
MIRT2456982	hsa-miR-646	CLIP-seq
MIRT2688390	hsa-miR-647	CLIP-seq

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Interactions View interactions

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
CATAPLEXY AND NARCOLEPSY	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NARCOLEPSY-CATAPLEXY SYNDROME	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PPAN-P2RY11-related disorder	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenocarcinoma of lung (disorder)	Lung adenocarcinoma	CTD_human_DG	27602772		★☆☆☆☆ Found in Text Mining only
Amnesia, Transient Global	Amnesia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Astrocytoma	Astrocytoma	BEFREE	24524250		★☆☆☆☆ Found in Text Mining only
Autoimmune Diseases	Autoimmune Diseases	BEFREE	21170044		★☆☆☆☆ Found in Text Mining only
Autoimmune Diseases	Autoimmune disease	Pubtator	21170044	Associate	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	32444848	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	34741342	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Squamous Cell	Squamous cell carcinoma	Pubtator	18057535	Associate	★☆☆☆☆ Found in Text Mining only
Cataplexy	Cataplexy	HPO_DG			★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	34768902	Associate	★☆☆☆☆ Found in Text Mining only
Conventional (Clear Cell) Renal Cell Carcinoma	Renal Carcinoma	BEFREE	31300850		★☆☆☆☆ Found in Text Mining only
Coronary Arteriosclerosis	Coronary Arteriosclerosis	BEFREE	30711276		★☆☆☆☆ Found in Text Mining only
Cystic Fibrosis	Cystic Fibrosis	BEFREE	24588705		★☆☆☆☆ Found in Text Mining only
Dementia	Dementia	BEFREE	25669430		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 2	Diabetes mellitus, type 2	Pubtator	30592156	Associate	★☆☆☆☆ Found in Text Mining only
Hallucinations	Hallucinations	HPO_DG			★☆☆☆☆ Found in Text Mining only
Hypoxia	Hypoxia	Pubtator	26433470	Inhibit	★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	28418839		★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	26491047	Associate	★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	17135283		★☆☆☆☆ Found in Text Mining only
Myocardial Infarction	Myocardial infarction	Pubtator	37798364	Associate	★☆☆☆☆ Found in Text Mining only
Myocardial Ischemia	Myocardial Ischemia	BEFREE	30711276		★☆☆☆☆ Found in Text Mining only
Narcolepsy	Narcolepsy	BEFREE	21170044, 22177342, 23497937, 23725858, 25669430, 27305985, 28460015, 31450027		★☆☆☆☆ Found in Text Mining only
Narcolepsy	Narcolepsy	CTD_human_DG	21170044		★☆☆☆☆ Found in Text Mining only
Narcolepsy	Narcolepsy	Pubtator	21170044, 22177342, 24204295	Associate	★☆☆☆☆ Found in Text Mining only
Narcolepsy	Narcolepsy	ORPHANET_DG	24204295		★☆☆☆☆ Found in Text Mining only
Narcolepsy	Narcolepsy	GWASCAT_DG	24204295		★☆☆☆☆ Found in Text Mining only
Narcolepsy	Narcolepsy	GWASDB_DG	24204295		★☆☆☆☆ Found in Text Mining only
Narcolepsy 1	Narcolepsy	CLINVAR_DG	25669430		★☆☆☆☆ Found in Text Mining only
Narcolepsy 1	Narcolepsy	Pubtator	33710305	Associate	★☆☆☆☆ Found in Text Mining only
Narcolepsy type 1	Narcolepsy	Orphanet			★☆☆☆☆ Found in Text Mining only
Narcolepsy-Cataplexy Syndrome	Narcolepsy-Cataplexy Syndrome	CTD_human_DG	21170044		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Narcolepsy-Cataplexy Syndrome	Narcolepsy-Cataplexy Syndrome	ORPHANET_DG	24204295		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Narcolepsy-Cataplexy Syndrome	Narcolepsy-Cataplexy Syndrome	BEFREE	28460015		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Obesity	Obesity	HPO_DG			★☆☆☆☆ Found in Text Mining only
Oropharyngeal Carcinoma	Oropharyngeal Carcinoma	BEFREE	29934978		★☆☆☆☆ Found in Text Mining only
Presenile dementia	Senile Dementia	BEFREE	25669430		★☆☆☆☆ Found in Text Mining only
Rheumatoid Arthritis	Rheumatoid arthritis	BEFREE	31301116		★☆☆☆☆ Found in Text Mining only
Septicemia	Septicemia	BEFREE	30787105		★☆☆☆☆ Found in Text Mining only
Sleep Deprivation	Sleep deprivation	Pubtator	33710305	Associate	★☆☆☆☆ Found in Text Mining only