AURKA (aurora kinase A)

Gene

• Entrez ID: 6790
• Gene name: Aurora kinase A
• Gene symbol: AURKA
• Synonyms (NCBI Gene): AIK, ARK1, AURA, BTAK, PPP1R47, STK15, STK6, STK7
• Chromosome: 20
• Chromosome location: 20q13.2
• Summary: The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cel

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs2273535	A>C,G,T	Risk-factor	Missense variant, coding sequence variant
rs1455074519	G>A,T	Likely-pathogenic	Missense variant, synonymous variant, coding sequence variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT005051	hsa-let-7b-5p	Microarray	17699775
MIRT020589	hsa-miR-155-5p	Proteomics	18668040
MIRT022391	hsa-miR-124-3p	Proteomics;Microarray	18668037
MIRT005051	hsa-let-7b-5p	Proteomics	18668040
MIRT044891	hsa-miR-193a-3p	CLASH	23622248
MIRT568366	hsa-miR-581	PAR-CLIP	20371350
MIRT568365	hsa-miR-3616-3p	PAR-CLIP	20371350
MIRT568364	hsa-miR-4721	PAR-CLIP	20371350
MIRT568363	hsa-miR-518d-5p	PAR-CLIP	20371350
MIRT568362	hsa-miR-518e-5p	PAR-CLIP	20371350
MIRT568361	hsa-miR-518f-5p	PAR-CLIP	20371350
MIRT568360	hsa-miR-519a-5p	PAR-CLIP	20371350
MIRT568359	hsa-miR-519b-5p	PAR-CLIP	20371350
MIRT568358	hsa-miR-519c-5p	PAR-CLIP	20371350
MIRT568357	hsa-miR-520c-5p	PAR-CLIP	20371350
MIRT568356	hsa-miR-522-5p	PAR-CLIP	20371350
MIRT568355	hsa-miR-523-5p	PAR-CLIP	20371350
MIRT568354	hsa-miR-526a	PAR-CLIP	20371350
MIRT568353	hsa-miR-4777-5p	PAR-CLIP	20371350
MIRT568352	hsa-miR-6834-5p	PAR-CLIP	20371350
MIRT568351	hsa-miR-1226-5p	PAR-CLIP	20371350
MIRT568350	hsa-miR-6734-5p	PAR-CLIP	20371350
MIRT568349	hsa-miR-578	PAR-CLIP	20371350
MIRT559289	hsa-miR-6779-3p	PAR-CLIP	21572407
MIRT541460	hsa-miR-154-5p	PAR-CLIP	21572407
MIRT559288	hsa-miR-8076	PAR-CLIP	21572407
MIRT559287	hsa-miR-183-5p	PAR-CLIP	21572407
MIRT559286	hsa-miR-6748-3p	PAR-CLIP	21572407
MIRT559285	hsa-miR-4421	PAR-CLIP	21572407
MIRT559284	hsa-miR-5699-3p	PAR-CLIP	21572407
MIRT559283	hsa-miR-149-5p	PAR-CLIP	21572407
MIRT559282	hsa-miR-885-3p	PAR-CLIP	21572407
MIRT559281	hsa-miR-4284	PAR-CLIP	21572407
MIRT559280	hsa-miR-24-3p	PAR-CLIP	21572407
MIRT559279	hsa-miR-4326	PAR-CLIP	21572407
MIRT559278	hsa-miR-7152-5p	PAR-CLIP	21572407
MIRT541473	hsa-miR-92a-3p	PAR-CLIP	21572407
MIRT541472	hsa-miR-32-5p	PAR-CLIP	21572407
MIRT541471	hsa-miR-25-3p	PAR-CLIP	21572407
MIRT541470	hsa-miR-92b-3p	PAR-CLIP	21572407
MIRT541469	hsa-miR-363-3p	PAR-CLIP	21572407
MIRT541468	hsa-miR-367-3p	PAR-CLIP	21572407
MIRT541467	hsa-miR-4476	PAR-CLIP	21572407
MIRT541466	hsa-miR-6876-5p	PAR-CLIP	21572407
MIRT541465	hsa-miR-4436b-3p	PAR-CLIP	21572407
MIRT541464	hsa-miR-4632-5p	PAR-CLIP	21572407
MIRT541462	hsa-miR-6735-5p	PAR-CLIP	21572407
MIRT541463	hsa-miR-6879-5p	PAR-CLIP	21572407
MIRT541461	hsa-miR-7843-5p	PAR-CLIP	21572407
MIRT541460	hsa-miR-154-5p	PAR-CLIP	21572407
MIRT541459	hsa-miR-6736-3p	PAR-CLIP	21572407
MIRT296432	hsa-miR-3918	PAR-CLIP	21572407
MIRT541458	hsa-miR-4448	PAR-CLIP	21572407
MIRT541457	hsa-miR-137	PAR-CLIP	21572407
MIRT541456	hsa-miR-3127-5p	PAR-CLIP	21572407
MIRT541473	hsa-miR-92a-3p	HITS-CLIP	22473208
MIRT541470	hsa-miR-92b-3p	HITS-CLIP	22473208
MIRT541472	hsa-miR-32-5p	HITS-CLIP	22473208
MIRT541472	hsa-miR-32-5p	Luciferase reporter assay, qRT-PCR, Western blot	26036635
MIRT732545	hsa-miR-106a-3p	RNA-seq	33037409
MIRT734205	hsa-miR-4715-3p	Luciferase reporter assay, qRT-PCR, Western blotting	31740746
MIRT734205	hsa-miR-4715-3p	Luciferase reporter assay, qRT-PCR, Western blotting	31740746
MIRT734205	hsa-miR-4715-3p	Luciferase reporter assay, qRT-PCR, Western blotting	31740746
MIRT734205	hsa-miR-4715-3p	Luciferase reporter assay, qRT-PCR, Western blotting	31740746
MIRT736544	hsa-let-7a-5p	Luciferase reporter assay, Western blotting, qRT-PCR	32849824
MIRT736786	hsa-miR-621	Luciferase reporter assay, qRT-PCR	33629578
MIRT737291	hsa-miR-490-3p	qRT-PCR	32733789
MIRT737358	hsa-miR-497-3p	RNA-seq	32156775
MIRT568366	hsa-miR-581	PAR-CLIP	20371350
MIRT568365	hsa-miR-3616-3p	PAR-CLIP	20371350
MIRT568364	hsa-miR-4721	PAR-CLIP	20371350
MIRT568363	hsa-miR-518d-5p	PAR-CLIP	20371350
MIRT568362	hsa-miR-518e-5p	PAR-CLIP	20371350
MIRT568361	hsa-miR-518f-5p	PAR-CLIP	20371350
MIRT568360	hsa-miR-519a-5p	PAR-CLIP	20371350
MIRT568359	hsa-miR-519b-5p	PAR-CLIP	20371350
MIRT568358	hsa-miR-519c-5p	PAR-CLIP	20371350
MIRT568357	hsa-miR-520c-5p	PAR-CLIP	20371350
MIRT568356	hsa-miR-522-5p	PAR-CLIP	20371350
MIRT568355	hsa-miR-523-5p	PAR-CLIP	20371350
MIRT568354	hsa-miR-526a	PAR-CLIP	20371350
MIRT568353	hsa-miR-4777-5p	PAR-CLIP	20371350
MIRT568352	hsa-miR-6834-5p	PAR-CLIP	20371350
MIRT568351	hsa-miR-1226-5p	PAR-CLIP	20371350
MIRT568350	hsa-miR-6734-5p	PAR-CLIP	20371350
MIRT568349	hsa-miR-578	PAR-CLIP	20371350
MIRT559289	hsa-miR-6779-3p	PAR-CLIP	21572407
MIRT541460	hsa-miR-154-5p	PAR-CLIP	21572407
MIRT559288	hsa-miR-8076	PAR-CLIP	21572407
MIRT559287	hsa-miR-183-5p	PAR-CLIP	21572407
MIRT559286	hsa-miR-6748-3p	PAR-CLIP	21572407
MIRT559285	hsa-miR-4421	PAR-CLIP	21572407
MIRT559284	hsa-miR-5699-3p	PAR-CLIP	21572407
MIRT559283	hsa-miR-149-5p	PAR-CLIP	21572407
MIRT559282	hsa-miR-885-3p	PAR-CLIP	21572407
MIRT559281	hsa-miR-4284	PAR-CLIP	21572407
MIRT559280	hsa-miR-24-3p	PAR-CLIP	21572407
MIRT559279	hsa-miR-4326	PAR-CLIP	21572407
MIRT559278	hsa-miR-7152-5p	PAR-CLIP	21572407
MIRT541473	hsa-miR-92a-3p	PAR-CLIP	21572407
MIRT541472	hsa-miR-32-5p	PAR-CLIP	21572407
MIRT541471	hsa-miR-25-3p	PAR-CLIP	21572407
MIRT541470	hsa-miR-92b-3p	PAR-CLIP	21572407
MIRT541469	hsa-miR-363-3p	PAR-CLIP	21572407
MIRT541468	hsa-miR-367-3p	PAR-CLIP	21572407
MIRT541467	hsa-miR-4476	PAR-CLIP	21572407
MIRT541466	hsa-miR-6876-5p	PAR-CLIP	21572407
MIRT541465	hsa-miR-4436b-3p	PAR-CLIP	21572407
MIRT541464	hsa-miR-4632-5p	PAR-CLIP	21572407
MIRT541462	hsa-miR-6735-5p	PAR-CLIP	21572407
MIRT541463	hsa-miR-6879-5p	PAR-CLIP	21572407
MIRT541461	hsa-miR-7843-5p	PAR-CLIP	21572407
MIRT541460	hsa-miR-154-5p	PAR-CLIP	21572407
MIRT541459	hsa-miR-6736-3p	PAR-CLIP	21572407
MIRT296432	hsa-miR-3918	PAR-CLIP	21572407
MIRT541458	hsa-miR-4448	PAR-CLIP	21572407
MIRT541457	hsa-miR-137	PAR-CLIP	21572407
MIRT541456	hsa-miR-3127-5p	PAR-CLIP	21572407
MIRT812105	hsa-let-7a	CLIP-seq
MIRT812106	hsa-let-7b	CLIP-seq
MIRT812107	hsa-let-7c	CLIP-seq
MIRT812108	hsa-let-7d	CLIP-seq
MIRT812109	hsa-let-7e	CLIP-seq
MIRT812110	hsa-let-7f	CLIP-seq
MIRT812111	hsa-let-7g	CLIP-seq
MIRT812112	hsa-let-7i	CLIP-seq
MIRT812113	hsa-miR-1179	CLIP-seq
MIRT812114	hsa-miR-129-3p	CLIP-seq
MIRT812115	hsa-miR-154	CLIP-seq
MIRT812116	hsa-miR-199a-3p	CLIP-seq
MIRT812117	hsa-miR-199b-3p	CLIP-seq
MIRT812118	hsa-miR-2278	CLIP-seq
MIRT812119	hsa-miR-25	CLIP-seq
MIRT812120	hsa-miR-300	CLIP-seq
MIRT812121	hsa-miR-3129-5p	CLIP-seq
MIRT812122	hsa-miR-3180	CLIP-seq
MIRT812123	hsa-miR-3180-3p	CLIP-seq
MIRT812124	hsa-miR-3182	CLIP-seq
MIRT812125	hsa-miR-3196	CLIP-seq
MIRT812126	hsa-miR-32	CLIP-seq
MIRT812127	hsa-miR-3200-3p	CLIP-seq
MIRT812128	hsa-miR-329	CLIP-seq
MIRT812129	hsa-miR-362-3p	CLIP-seq
MIRT812130	hsa-miR-363	CLIP-seq
MIRT812131	hsa-miR-367	CLIP-seq
MIRT812132	hsa-miR-3680	CLIP-seq
MIRT812133	hsa-miR-3686	CLIP-seq
MIRT812134	hsa-miR-3689d	CLIP-seq
MIRT812135	hsa-miR-3713	CLIP-seq
MIRT812136	hsa-miR-381	CLIP-seq
MIRT812137	hsa-miR-3919	CLIP-seq
MIRT812138	hsa-miR-3921	CLIP-seq
MIRT812139	hsa-miR-3927	CLIP-seq
MIRT812140	hsa-miR-3941	CLIP-seq
MIRT812141	hsa-miR-4251	CLIP-seq
MIRT812142	hsa-miR-4274	CLIP-seq
MIRT812143	hsa-miR-4307	CLIP-seq
MIRT812144	hsa-miR-4310	CLIP-seq
MIRT812145	hsa-miR-4329	CLIP-seq
MIRT812146	hsa-miR-4451	CLIP-seq
MIRT812147	hsa-miR-4458	CLIP-seq
MIRT812148	hsa-miR-4500	CLIP-seq
MIRT812149	hsa-miR-4509	CLIP-seq
MIRT812150	hsa-miR-4643	CLIP-seq
MIRT812151	hsa-miR-4653-5p	CLIP-seq
MIRT812152	hsa-miR-466	CLIP-seq
MIRT812153	hsa-miR-4672	CLIP-seq
MIRT812154	hsa-miR-4694-3p	CLIP-seq
MIRT812155	hsa-miR-4717-3p	CLIP-seq
MIRT812156	hsa-miR-4732-5p	CLIP-seq
MIRT812157	hsa-miR-4733-5p	CLIP-seq
MIRT812158	hsa-miR-4742-3p	CLIP-seq
MIRT812159	hsa-miR-4757-5p	CLIP-seq
MIRT812160	hsa-miR-4802-5p	CLIP-seq
MIRT812161	hsa-miR-510	CLIP-seq
MIRT812162	hsa-miR-522	CLIP-seq
MIRT812163	hsa-miR-603	CLIP-seq
MIRT812164	hsa-miR-605	CLIP-seq
MIRT812165	hsa-miR-642b	CLIP-seq
MIRT812166	hsa-miR-759	CLIP-seq
MIRT812167	hsa-miR-92a	CLIP-seq
MIRT812168	hsa-miR-92b	CLIP-seq
MIRT812169	hsa-miR-936	CLIP-seq
MIRT812170	hsa-miR-938	CLIP-seq
MIRT812171	hsa-miR-98	CLIP-seq
MIRT812105	hsa-let-7a	CLIP-seq
MIRT812106	hsa-let-7b	CLIP-seq
MIRT812107	hsa-let-7c	CLIP-seq
MIRT812108	hsa-let-7d	CLIP-seq
MIRT812109	hsa-let-7e	CLIP-seq
MIRT812110	hsa-let-7f	CLIP-seq
MIRT812111	hsa-let-7g	CLIP-seq
MIRT812112	hsa-let-7i	CLIP-seq
MIRT812113	hsa-miR-1179	CLIP-seq
MIRT812118	hsa-miR-2278	CLIP-seq
MIRT812172	hsa-miR-337-3p	CLIP-seq
MIRT812173	hsa-miR-342-5p	CLIP-seq
MIRT812174	hsa-miR-3687	CLIP-seq
MIRT812134	hsa-miR-3689d	CLIP-seq
MIRT812135	hsa-miR-3713	CLIP-seq
MIRT812139	hsa-miR-3927	CLIP-seq
MIRT812144	hsa-miR-4310	CLIP-seq
MIRT812175	hsa-miR-4442	CLIP-seq
MIRT812146	hsa-miR-4451	CLIP-seq
MIRT812147	hsa-miR-4458	CLIP-seq
MIRT812148	hsa-miR-4500	CLIP-seq
MIRT812149	hsa-miR-4509	CLIP-seq
MIRT812176	hsa-miR-4655-5p	CLIP-seq
MIRT812177	hsa-miR-4664-5p	CLIP-seq
MIRT812154	hsa-miR-4694-3p	CLIP-seq
MIRT812156	hsa-miR-4732-5p	CLIP-seq
MIRT812157	hsa-miR-4733-5p	CLIP-seq
MIRT812160	hsa-miR-4802-5p	CLIP-seq
MIRT812162	hsa-miR-522	CLIP-seq
MIRT812164	hsa-miR-605	CLIP-seq
MIRT812171	hsa-miR-98	CLIP-seq
MIRT812178	hsa-miR-149	CLIP-seq
MIRT812115	hsa-miR-154	CLIP-seq
MIRT812179	hsa-miR-183	CLIP-seq
MIRT812180	hsa-miR-24	CLIP-seq
MIRT812120	hsa-miR-300	CLIP-seq
MIRT812136	hsa-miR-381	CLIP-seq
MIRT812181	hsa-miR-4713-5p	CLIP-seq
MIRT812166	hsa-miR-759	CLIP-seq
MIRT1940204	hsa-miR-1228	CLIP-seq
MIRT812115	hsa-miR-154	CLIP-seq
MIRT1940205	hsa-miR-186	CLIP-seq
MIRT812119	hsa-miR-25	CLIP-seq
MIRT1940206	hsa-miR-3135	CLIP-seq
MIRT1940207	hsa-miR-3160-5p	CLIP-seq
MIRT812122	hsa-miR-3180	CLIP-seq
MIRT812123	hsa-miR-3180-3p	CLIP-seq
MIRT812125	hsa-miR-3196	CLIP-seq
MIRT812126	hsa-miR-32	CLIP-seq
MIRT812127	hsa-miR-3200-3p	CLIP-seq
MIRT812128	hsa-miR-329	CLIP-seq
MIRT1940208	hsa-miR-3545-5p	CLIP-seq
MIRT812129	hsa-miR-362-3p	CLIP-seq
MIRT812130	hsa-miR-363	CLIP-seq
MIRT812131	hsa-miR-367	CLIP-seq
MIRT812132	hsa-miR-3680	CLIP-seq
MIRT1940209	hsa-miR-370	CLIP-seq
MIRT1940210	hsa-miR-3929	CLIP-seq
MIRT812140	hsa-miR-3941	CLIP-seq
MIRT812142	hsa-miR-4274	CLIP-seq
MIRT1940211	hsa-miR-4419b	CLIP-seq
MIRT1940212	hsa-miR-4427	CLIP-seq
MIRT1940213	hsa-miR-4438	CLIP-seq
MIRT1940214	hsa-miR-4478	CLIP-seq
MIRT1940215	hsa-miR-4491	CLIP-seq
MIRT1940216	hsa-miR-4633-3p	CLIP-seq
MIRT1940217	hsa-miR-4657	CLIP-seq
MIRT812152	hsa-miR-466	CLIP-seq
MIRT1940218	hsa-miR-4663	CLIP-seq
MIRT812153	hsa-miR-4672	CLIP-seq
MIRT1940219	hsa-miR-4680-3p	CLIP-seq
MIRT812155	hsa-miR-4717-3p	CLIP-seq
MIRT1940220	hsa-miR-4762-3p	CLIP-seq
MIRT812161	hsa-miR-510	CLIP-seq
MIRT812163	hsa-miR-603	CLIP-seq
MIRT812165	hsa-miR-642b	CLIP-seq
MIRT812166	hsa-miR-759	CLIP-seq
MIRT812167	hsa-miR-92a	CLIP-seq
MIRT812168	hsa-miR-92b	CLIP-seq
MIRT1940204	hsa-miR-1228	CLIP-seq
MIRT2179093	hsa-miR-124	CLIP-seq
MIRT2179094	hsa-miR-1321	CLIP-seq
MIRT812115	hsa-miR-154	CLIP-seq
MIRT2179095	hsa-miR-1972	CLIP-seq
MIRT812116	hsa-miR-199a-3p	CLIP-seq
MIRT812117	hsa-miR-199b-3p	CLIP-seq
MIRT812118	hsa-miR-2278	CLIP-seq
MIRT2179096	hsa-miR-2355-5p	CLIP-seq
MIRT812119	hsa-miR-25	CLIP-seq
MIRT812120	hsa-miR-300	CLIP-seq
MIRT812121	hsa-miR-3129-5p	CLIP-seq
MIRT2179097	hsa-miR-3155	CLIP-seq
MIRT2179098	hsa-miR-3155b	CLIP-seq
MIRT2179099	hsa-miR-3162-5p	CLIP-seq
MIRT812122	hsa-miR-3180	CLIP-seq
MIRT812123	hsa-miR-3180-3p	CLIP-seq
MIRT812125	hsa-miR-3196	CLIP-seq
MIRT812126	hsa-miR-32	CLIP-seq
MIRT812127	hsa-miR-3200-3p	CLIP-seq
MIRT812172	hsa-miR-337-3p	CLIP-seq
MIRT812173	hsa-miR-342-5p	CLIP-seq
MIRT1940208	hsa-miR-3545-5p	CLIP-seq
MIRT812130	hsa-miR-363	CLIP-seq
MIRT812131	hsa-miR-367	CLIP-seq
MIRT2179100	hsa-miR-3679-3p	CLIP-seq
MIRT812132	hsa-miR-3680	CLIP-seq
MIRT812174	hsa-miR-3687	CLIP-seq
MIRT1940209	hsa-miR-370	CLIP-seq
MIRT2179101	hsa-miR-3714	CLIP-seq
MIRT812136	hsa-miR-381	CLIP-seq
MIRT2179102	hsa-miR-3910	CLIP-seq
MIRT812137	hsa-miR-3919	CLIP-seq
MIRT812139	hsa-miR-3927	CLIP-seq
MIRT1940210	hsa-miR-3929	CLIP-seq
MIRT812140	hsa-miR-3941	CLIP-seq
MIRT812142	hsa-miR-4274	CLIP-seq
MIRT2179103	hsa-miR-4286	CLIP-seq
MIRT1940211	hsa-miR-4419b	CLIP-seq
MIRT1940212	hsa-miR-4427	CLIP-seq
MIRT1940213	hsa-miR-4438	CLIP-seq
MIRT812175	hsa-miR-4442	CLIP-seq
MIRT812146	hsa-miR-4451	CLIP-seq
MIRT1940214	hsa-miR-4478	CLIP-seq
MIRT1940215	hsa-miR-4491	CLIP-seq
MIRT2179104	hsa-miR-4650-5p	CLIP-seq
MIRT812176	hsa-miR-4655-5p	CLIP-seq
MIRT1940217	hsa-miR-4657	CLIP-seq
MIRT1940218	hsa-miR-4663	CLIP-seq
MIRT812177	hsa-miR-4664-5p	CLIP-seq
MIRT812156	hsa-miR-4732-5p	CLIP-seq
MIRT812157	hsa-miR-4733-5p	CLIP-seq
MIRT2179105	hsa-miR-4739	CLIP-seq
MIRT2179106	hsa-miR-4756-5p	CLIP-seq
MIRT2179107	hsa-miR-484	CLIP-seq
MIRT2179108	hsa-miR-506	CLIP-seq
MIRT812161	hsa-miR-510	CLIP-seq
MIRT2179109	hsa-miR-562	CLIP-seq
MIRT812164	hsa-miR-605	CLIP-seq
MIRT812166	hsa-miR-759	CLIP-seq
MIRT812167	hsa-miR-92a	CLIP-seq
MIRT812168	hsa-miR-92b	CLIP-seq
MIRT812169	hsa-miR-936	CLIP-seq
MIRT812116	hsa-miR-199a-3p	CLIP-seq
MIRT812117	hsa-miR-199b-3p	CLIP-seq
MIRT812121	hsa-miR-3129-5p	CLIP-seq
MIRT812169	hsa-miR-936	CLIP-seq
MIRT812140	hsa-miR-3941	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
E2F1	Activation	20300951
E2F3	Activation	18776222
MED1	Activation	16574658
OTX2	Activation	21047732

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000086	Process	G2/M transition of mitotic cell cycle	TAS
GO:0000166	Function	Nucleotide binding	IEA
GO:0000212	Process	Meiotic spindle organization	IEA
GO:0000212	Process	Meiotic spindle organization	IEA
GO:0000226	Process	Microtubule cytoskeleton organization	IEA
GO:0000226	Process	Microtubule cytoskeleton organization	IEA
GO:0000278	Process	Mitotic cell cycle	IEA
GO:0000278	Process	Mitotic cell cycle	IEA
GO:0000278	Process	Mitotic cell cycle	TAS	9153231
GO:0000776	Component	Kinetochore	IBA
GO:0000922	Component	Spindle pole	IBA
GO:0000922	Component	Spindle pole	IEA
GO:0004672	Function	Protein kinase activity	IDA	14580337, 19801554, 21600873
GO:0004672	Function	Protein kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	EXP	13678582, 18566290, 21807936
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	IMP	28218735
GO:0004674	Function	Protein serine/threonine kinase activity	TAS
GO:0004712	Function	Protein serine/threonine/tyrosine kinase activity	IEA
GO:0004712	Function	Protein serine/threonine/tyrosine kinase activity	TAS	19774610
GO:0005515	Function	Protein binding	IPI	12244051, 14580337, 15987997, 16890155, 17604723, 17726514, 17939994, 18361916, 18521620, 18615013, 18662907, 18663142, 19111882, 19357306, 19801554, 20360068, 20460379, 20596670, 20643351, 21242313, 21821029, 22014574, 22110403, 22305495, 22306998, 22340593, 23213400, 23520446, 237
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	20531406
GO:0005634	Component	Nucleus	TAS	9153231
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IBA
GO:0005813	Component	Centrosome	IDA	17726514, 21399614, 21600873, 23213400, 25657325, 30538148
GO:0005813	Component	Centrosome	IEA
GO:0005813	Component	Centrosome	TAS	19774610
GO:0005814	Component	Centriole	IEA
GO:0005815	Component	Microtubule organizing center	IEA
GO:0005819	Component	Spindle	TAS	9153231, 19774610
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IEA
GO:0005874	Component	Microtubule	IEA
GO:0005876	Component	Spindle microtubule	IDA	19801554
GO:0005886	Component	Plasma membrane	IEA
GO:0005929	Component	Cilium	IEA
GO:0006338	Process	Chromatin remodeling	IEA
GO:0006468	Process	Protein phosphorylation	IDA	21600873
GO:0006468	Process	Protein phosphorylation	IDA	21820309
GO:0006468	Process	Protein phosphorylation	TAS	9153231
GO:0006915	Process	Apoptotic process	IEA
GO:0007051	Process	Spindle organization	IMP	21820309
GO:0007052	Process	Mitotic spindle organization	IBA
GO:0007052	Process	Mitotic spindle organization	IEA
GO:0007052	Process	Mitotic spindle organization	IEA
GO:0007057	Process	Spindle assembly involved in female meiosis I	IEA
GO:0007098	Process	Centrosome cycle	IEA
GO:0007098	Process	Centrosome cycle	IEA
GO:0007100	Process	Mitotic centrosome separation	IEA
GO:0007100	Process	Mitotic centrosome separation	IEA
GO:0009611	Process	Response to wounding	IDA	19435814
GO:0009948	Process	Anterior/posterior axis specification	IEA
GO:0010389	Process	Regulation of G2/M transition of mitotic cell cycle	TAS
GO:0010629	Process	Negative regulation of gene expression	IMP	28218735
GO:0014069	Component	Postsynaptic density	IEA
GO:0015630	Component	Microtubule cytoskeleton	IDA	19801554
GO:0016020	Component	Membrane	IEA
GO:0016301	Function	Kinase activity	IEA
GO:0016323	Component	Basolateral plasma membrane	IEA
GO:0016323	Component	Basolateral plasma membrane	ISS
GO:0016740	Function	Transferase activity	IEA
GO:0018105	Process	Peptidyl-serine phosphorylation	IMP	28218735
GO:0019901	Function	Protein kinase binding	IPI	18615013
GO:0030030	Process	Cell projection organization	IEA
GO:0030496	Component	Midbody	IEA
GO:0030496	Component	Midbody	TAS	19774610
GO:0031616	Component	Spindle pole centrosome	IDA	19801554
GO:0031625	Function	Ubiquitin protein ligase binding	IEA
GO:0031647	Process	Regulation of protein stability	IMP	15987997
GO:0032091	Process	Negative regulation of protein binding	IDA	21820309
GO:0032133	Component	Chromosome passenger complex	IBA
GO:0032436	Process	Positive regulation of proteasomal ubiquitin-dependent protein catabolic process	IEA
GO:0032465	Process	Regulation of cytokinesis	IBA
GO:0032886	Process	Regulation of microtubule-based process	IEA
GO:0035175	Function	Histone H3S10 kinase activity	IEA
GO:0036064	Component	Ciliary basal body	IDA	17604723
GO:0042585	Component	Germinal vesicle	IEA
GO:0042995	Component	Cell projection	IEA
GO:0043005	Component	Neuron projection	IEA
GO:0043066	Process	Negative regulation of apoptotic process	IEA
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IEA
GO:0043203	Component	Axon hillock	IEA
GO:0044839	Process	Cell cycle G2/M phase transition	IEA
GO:0045120	Component	Pronucleus	IEA
GO:0045840	Process	Positive regulation of mitotic nuclear division	TAS	19774610
GO:0045931	Process	Positive regulation of mitotic cell cycle	ISS
GO:0046605	Process	Regulation of centrosome cycle	TAS	19774610
GO:0046777	Process	Protein autophosphorylation	TAS	19774610
GO:0046982	Function	Protein heterodimerization activity	IPI	20460379
GO:0048471	Component	Perinuclear region of cytoplasm	IDA	20531406
GO:0051233	Component	Spindle midzone	IBA
GO:0051301	Process	Cell division	IEA
GO:0051321	Process	Meiotic cell cycle	IEA
GO:0051321	Process	Meiotic cell cycle	IEA
GO:0051642	Process	Centrosome localization	IEA
GO:0061523	Process	Cilium disassembly	IMP	17604723
GO:0071539	Process	Protein localization to centrosome	IEA
GO:0072686	Component	Mitotic spindle	IDA
GO:0072686	Component	Mitotic spindle	IEA
GO:0072687	Component	Meiotic spindle	IEA
GO:0090068	Process	Positive regulation of cell cycle process	IEA
GO:0090141	Process	Positive regulation of mitochondrial fission	IMP	21822277
GO:0097421	Process	Liver regeneration	IDA	19435814
GO:0097431	Component	Mitotic spindle pole	IDA	25657325
GO:0098978	Component	Glutamatergic synapse	IEA
GO:0106310	Function	Protein serine kinase activity	IEA
GO:0140677	Function	Molecular function activator activity	EXP	12237287
GO:1900195	Process	Positive regulation of oocyte maturation	IEA
GO:1901796	Process	Regulation of signal transduction by p53 class mediator	IEA
GO:1901796	Process	Regulation of signal transduction by p53 class mediator	TAS
GO:1990138	Process	Neuron projection extension	IEA

Other IDs

• MIM: 603072
• HGNC: 11393
• e!Ensembl: ENSG00000087586

Protein

• UniProt ID: O14965
• Protein name: Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (Breast tumor-amplified kinase) (Ipl1- and aurora-related kinase 1) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/
• Protein function: Mitotic serine/threonine kinase that contributes to the regulation of cell cycle progression (PubMed:11039908, PubMed:12390251, PubMed:17125279, PubMed:17360485, PubMed:18615013, PubMed:26246606). Associates with the centrosome and the spindle m
• PDB: 1MQ4, 1MUO, 1OL5, 1OL6, 1OL7, 2BMC, 2C6D, 2C6E, 2DWB, 2J4Z, 2J50, 2NP8, 2W1C, 2W1D, 2W1E, 2W1F, 2W1G, 2WQE, 2WTV, 2WTW, 2X6D, 2X6E, 2X81, 2XNE, 2XNG, 2XRU, 3COH, 3E5A, 3EFW, 3FDN, 3H0Y, 3H0Z, 3H10, 3HA6, 3K5U, 3LAU, 3M11, 3MYG, 3NRM, 3O50, 3O51, 3P9J, 3QBN, 3R21, 3R22, 3UNZ, 3UO4, 3UO5, 3UO6, 3UOD, 3UOH
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00069	Pkinase	133 → 383	Protein kinase domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.
• Sequence:

  MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRVPLQ
  AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
  EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
  EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
  ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
  IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
  SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS

• Sequence length: 403

Pathways

KEGG:

Oocyte meiosis
Progesterone-mediated oocyte maturation

Reactome:

APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Regulation of PLK1 Activity at G2/M Transition
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Regulation of TP53 Activity through Phosphorylation
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
AURKA Activation by TPX2
Interaction between PHLDA1 and AURKA

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Multiple myeloma	Likely pathogenic	rs1455074519	RCV000984118	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ANEUPLOIDY	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AURKA-related disorder	Benign; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST CANCER	—	GenCC	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST NEOPLASMS	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARCINOMA, HEPATOCELLULAR	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CHROMOSOMAL INSTABILITY	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colon cancer, susceptibility to	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colorectal cancer	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL NEOPLASMS	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INTELLECTUAL DISABILITY	—	Disgenet, GenCC Disgenet, GenCC	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
KIDNEY NEOPLASMS	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MELANOMA	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEUROBLASTOMA	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PERIPHERAL NERVOUS SYSTEM DISEASES	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATIC NEOPLASMS	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Acute lymphocytic leukemia	Lymphocytic Leukemia	BEFREE	24382688		★☆☆☆☆ Found in Text Mining only
Acute Megakaryocytic Leukemias	Megakaryocytic Leukemia	BEFREE	22863010, 23963861		★☆☆☆☆ Found in Text Mining only
Acute monocytic leukemia	Monocytic Leukemia	BEFREE	20303016, 29654398		★☆☆☆☆ Found in Text Mining only
Adenocarcinoma	Adenocarcinoma	BEFREE	16792546, 18311783, 21718475, 22302096, 23358695, 27624071		★☆☆☆☆ Found in Text Mining only
Adenocarcinoma	Adenocarcinoma	LHGDN	18284933, 18311783		★☆☆☆☆ Found in Text Mining only
Adenocarcinoma Of Esophagus	Esophageal Cancer	BEFREE	22302096		★☆☆☆☆ Found in Text Mining only
Adenocarcinoma of large intestine	Colorectal Cancer	UNIPROT_DG			★☆☆☆☆ Found in Text Mining only
Adenocarcinoma of lung (disorder)	Lung adenocarcinoma	BEFREE	27571708, 28869599, 28967900, 30478424, 30588191		★☆☆☆☆ Found in Text Mining only
Adenocarcinoma of prostate	Prostate adenocarcinoma	CGI_DG			★☆☆☆☆ Found in Text Mining only
Adenoma	Adenoma	BEFREE	20358421		★☆☆☆☆ Found in Text Mining only
Adenoma of large intestine	Colorectal adenoma	BEFREE	22207630, 25596657, 27329586		★☆☆☆☆ Found in Text Mining only
Adrenocortical Carcinoma	Adrenocortical carcinoma	Pubtator	12547710, 30413320, 32287321, 35500219, 38053725	Associate	★☆☆☆☆ Found in Text Mining only
Adult Acute Myeloblastic Leukemia	Myeloblastic Leukemia	BEFREE	29654398		★☆☆☆☆ Found in Text Mining only
Adult Malignant Peripheral Nerve Sheath Tumor	Malignant Peripheral Nerve Sheath Tumor	BEFREE	22811580		★☆☆☆☆ Found in Text Mining only
Adult Medulloblastoma	Medulloblastoma	BEFREE	15126347		★☆☆☆☆ Found in Text Mining only
Aneuploidy	Aneuploidy	Pubtator	11259099, 16790082, 17322345, 17438137, 17591802, 17627006, 18812553, 19648887, 19801554, 23092930, 25153724, 28102366	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Aneuploidy	Aneuploidy	Pubtator	11551964	Stimulate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Aneuploidy	Aneuploidy	Pubtator	25333414	Inhibit	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Angiofibroma	Angiofibroma	BEFREE	17120309		★☆☆☆☆ Found in Text Mining only
Angiofibroma	Angiofibroma	LHGDN	17120309		★☆☆☆☆ Found in Text Mining only
ANOPHTHALMIA AND PULMONARY HYPOPLASIA	Syndromic microphthalmia	BEFREE	28442587		★☆☆☆☆ Found in Text Mining only
Anophthalmia with pulmonary hypoplasia	Anophthalmia	Pubtator	39358545	Associate	★☆☆☆☆ Found in Text Mining only
Arteriosclerosis	Arteriosclerosis	BEFREE	30734057		★☆☆☆☆ Found in Text Mining only
Arthritis Rheumatoid	Rheumatoid arthritis	Pubtator	17082220, 36911710	Associate	★☆☆☆☆ Found in Text Mining only
Asthma	Asthma	BEFREE	28137284		★☆☆☆☆ Found in Text Mining only
Astrocytoma	Astrocytoma	BEFREE	28595628		★☆☆☆☆ Found in Text Mining only
Ataxia Telangiectasia	Ataxia telangiectasia	Pubtator	35782055	Associate	★☆☆☆☆ Found in Text Mining only
Atherosclerosis	Atherosclerosis	BEFREE	30734057		★☆☆☆☆ Found in Text Mining only
Atherosclerosis	Atherosclerosis	Pubtator	37005319	Associate	★☆☆☆☆ Found in Text Mining only
Autoimmune Diseases	Autoimmune Diseases	BEFREE	29802846		★☆☆☆☆ Found in Text Mining only
B-Cell Lymphomas	B-Cell Lymphoma	BEFREE	12716366		★☆☆☆☆ Found in Text Mining only
Barrett Esophagus	Barrett esophagus	Pubtator	17591802, 21470402, 24705000	Associate	★☆☆☆☆ Found in Text Mining only
Bladder Neoplasm	Bladder Neoplasm	BEFREE	12208897, 15547700, 17786310, 18361427, 18812553, 23403633, 28102366, 30547784		★☆☆☆☆ Found in Text Mining only
Bladder Neoplasm	Bladder Neoplasm	LHGDN	17786310, 18812553		★☆☆☆☆ Found in Text Mining only
Brain Neoplasms	Brain Neoplasms	BEFREE	15547718		★☆☆☆☆ Found in Text Mining only
Brain Neoplasms	Brain neoplasms	Pubtator	27926948, 37260393	Associate	★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	11190269, 11291073, 12883693, 14692019, 14693746, 15271853, 15271856, 15598762, 15688402, 16411056, 16715125, 16762494, 16849685, 17113223, 17627006, 20043089, 20464476, 21412660, 21584498, 21598251, 21630024, 22262870, 22465097, 22752290, 23186136, 23803310, 23925655, 24349361, 25154511, 25169513, 25288231, 25328151, 25667100, 25830658, 25996409, 26782714, 26925658, 27341528, 27461831, 27624071, 28114286, 28187748, 28647900, 28906374, 29863884, 29942081, 30104527, 30180881, 31406104, 9174055		★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	CTD_human_DG	18497064		★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	11259099, 14692019, 17627006, 18431743, 18628459, 20423983, 20473280, 21352579, 21412660, 21731694, 21761334, 21785467, 22262870, 22485147, 22538974, 22752290, 23026799, 23186136, 23324574, 23446853, 23627634, 24395524, 24876664, 25115395, 25254601, 25328151, 25830658, 26782714, 26854435, 26925658, 27223437, 28592839, 28647900, 28739725, 28906374, 29289986, 32404308, 32558176, 32932728, 33349071, 33499770, 33674187, 33877311, 34384030, 34675265, 34745136, 35351581, 35533650, 36892847, 36930083, 39198859, 40696381	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Breast Neoplasms	Breast neoplasm	Pubtator	34895070, 36113844	Stimulate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Burkitt Lymphoma	Burkitt lymphoma	Pubtator	37436268, 38099309	Associate	★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	14523000, 17322345, 18043979, 18820130, 19306133, 19412426, 19502819, 20423983, 21584819, 21829699, 23411487, 24778030, 25261653, 25436453, 25632068, 26481147, 26782714, 28079881, 28152093, 28427193, 29678897, 29693178, 31357906, 33629311, 34702201, 35782055, 36715516	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	BEFREE	14522886, 16222316, 22207630, 22586648, 23114921, 23186136		★☆☆☆☆ Found in Text Mining only
Carcinoma Adenoid Cystic	Adenoid cystic carcinoma	Pubtator	37861550	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Basal Cell	Basal cell carcinoma	Pubtator	17465238	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Ductal	Ductal carcinoma	Pubtator	28906374	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Ductal Breast	Ductal carcinoma of breast	Pubtator	28906374, 35533650	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	23255113, 23966163, 24722014, 28427193, 29333101, 29556353, 29843214, 30702595, 31322223, 31746405, 32390596, 32722976, 33051418, 33750838, 33946043, 34238253, 34257537, 35078445, 35720901, 36377304, 37861550	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Intraductal Noninfiltrating	Intraductal noninfiltrating carcinoma	Pubtator	35533650	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma of bladder	Bladder carcinoma	BEFREE	12208897, 15547700, 17786310, 18361427, 18812553, 21247708, 23403633, 28102366, 30547784		★☆☆☆☆ Found in Text Mining only
Carcinoma of larynx	Laryngeal carcinoma	BEFREE	16377583		★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	16792546, 16926177, 17908995, 21718475, 23520446, 25154511, 25882311, 30478424		★☆☆☆☆ Found in Text Mining only
Carcinoma Ovarian Epithelial	Epithelial ovarian carcinoma	Pubtator	30200102, 31336942, 33726773, 34794761	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	19551141, 23785518, 25183163, 25313256, 26061684, 27574806, 30518623, 32986937	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Small Cell	Small cell carcinoma	Pubtator	22586648, 25128228	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Small Cell	Small cell carcinoma	Pubtator	25512615	Stimulate	★☆☆☆☆ Found in Text Mining only
Carcinoma Squamous Cell	Squamous cell carcinoma	Pubtator	21718475, 28404933, 28949095, 31642613, 32340320, 36247089, 36352434, 37442189	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	12417041, 15466974, 15839305, 23334327, 23787073, 27250762, 30200102		★☆☆☆☆ Found in Text Mining only
Central Nervous System Neoplasms	Central Nervous System Neoplasms	BEFREE	29396807		★☆☆☆☆ Found in Text Mining only
cervical cancer	Cervical Cancer	BEFREE	21050672, 31706100		★☆☆☆☆ Found in Text Mining only
Cervical Intraepithelial Neoplasia	Cervical Intraepithelial Neoplasia	BEFREE	31642613		★☆☆☆☆ Found in Text Mining only
Cervix carcinoma	Cervix carcinoma	BEFREE	21050672, 31706100		★☆☆☆☆ Found in Text Mining only
Childhood Acute Lymphoblastic Leukemia	Lymphoblastic Leukemia	BEFREE	22940834		★☆☆☆☆ Found in Text Mining only
Childhood Malignant Peripheral Nerve Sheath Tumor	Malignant Peripheral Nerve Sheath Tumor	BEFREE	22811580		★☆☆☆☆ Found in Text Mining only
Childhood Medulloblastoma	Medulloblastoma	BEFREE	15126347		★☆☆☆☆ Found in Text Mining only
Chondrosarcoma	Chondrosarcoma	Pubtator	22809428	Inhibit	★☆☆☆☆ Found in Text Mining only
Chromosomal Instability	Chromosomal instability	Pubtator	17457043, 17591802, 17999753, 19412426, 24976383, 26831064	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Chromosomal Instability	Chromosomal instability	Pubtator	27329586	Stimulate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Chronic Lymphocytic Leukemia	Lymphocytic Leukemia	LHGDN	18931650		★☆☆☆☆ Found in Text Mining only
Chronic myeloproliferative disorder	Myeloproliferative disorder	BEFREE	31289316, 31837568		★☆☆☆☆ Found in Text Mining only
Colitis Ulcerative	Ulcerative colitis	Pubtator	17322345, 25333414	Associate	★☆☆☆☆ Found in Text Mining only
Colon Carcinoma	Colon Carcinoma	BEFREE	17999753, 19412426, 22311118, 30342037		★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Colonic Neoplasms	BEFREE	12881723, 15802297, 9771714		★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Colonic neoplasm	Pubtator	17999753, 26423403	Associate	★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	12883693, 16049965, 17003782, 19412426, 20358421, 20929925, 24104968, 26259750, 28000901, 28458622, 29760449, 30097580, 30118842, 30498084		★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	CTD_human_DG	24976383		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal Neoplasms	LHGDN	16049965, 17457043		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	17003782, 17457043, 17999753, 19412426, 19648887, 19690970, 19799648, 19801554, 20929925, 22240781, 24104968, 24125984, 24876664, 24976383, 25261653, 25632068, 26423403, 26497206, 28079881, 29760449, 31087508, 33422939, 34337875, 34700030, 34903321, 34959120, 35166647, 35774271, 36123948, 37394872, 38291041, 40018943	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colorectal Neoplasms	Colorectal Neoplasms	BEFREE	24876664, 25596657		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colorectal Neoplasms	Colorectal Neoplasms	CTD_human_DG	24976383		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colorectal Neoplasms Hereditary Nonpolyposis	Lynch syndrome	Pubtator	19690970	Associate	★☆☆☆☆ Found in Text Mining only
Congenital chromosomal disease	Congenital Chromosomal Disease	BEFREE	16377583, 20732714, 23317189		★☆☆☆☆ Found in Text Mining only
Conventional (Clear Cell) Renal Cell Carcinoma	Renal Carcinoma	BEFREE	17143471, 29845253, 30037856, 30518623		★☆☆☆☆ Found in Text Mining only
Corneal Neovascularization	Corneal neovascularization	Pubtator	33349071	Associate	★☆☆☆☆ Found in Text Mining only
Cyclic neutropenia	Cyclic Neutropenia	BEFREE	22240781		★☆☆☆☆ Found in Text Mining only
Degenerative polyarthritis	Arthritis	BEFREE	17082220, 30811038, 31357086		★☆☆☆☆ Found in Text Mining only
Depressive Disorder Major	Major depressive disorder	Pubtator	36911710	Associate	★☆☆☆☆ Found in Text Mining only
Donohue Syndrome	Leprechaunism syndrome	BEFREE	1968373, 2569023, 2574533, 2808704, 3631076		★☆☆☆☆ Found in Text Mining only
Donohue Syndrome	Donohue syndrome	Pubtator	2808704, 3631076	Associate	★☆☆☆☆ Found in Text Mining only
Ectodermal Dysplasia	Ectodermal dysplasia	Pubtator	12547710	Associate	★☆☆☆☆ Found in Text Mining only
ECTRODACTYLY, ECTODERMAL DYSPLASIA, AND CLEFT LIP/PALATE SYNDROME 1	Ectrodactyly	BEFREE	14522886, 21892093		★☆☆☆☆ Found in Text Mining only
Endocrine System Diseases	Endocrine system disease	Pubtator	36892847	Associate	★☆☆☆☆ Found in Text Mining only
Endometrial Carcinoma	Endometrial carcinoma	BEFREE	14522886, 27764792, 29963728		★☆☆☆☆ Found in Text Mining only
Endometrial Neoplasms	Endometrial neoplasm	Pubtator	33824269, 34725206, 35588308, 37803076	Associate	★☆☆☆☆ Found in Text Mining only
Epithelial ovarian cancer	Ovarian cancer	BEFREE	23334327, 30200102		★☆☆☆☆ Found in Text Mining only
Esophageal carcinoma	Esophageal Carcinoma	BEFREE	15867347, 22213102, 24349361		★☆☆☆☆ Found in Text Mining only
Esophageal Neoplasms	Esophagus Neoplasm	BEFREE	15867347, 22213102, 24349361		★☆☆☆☆ Found in Text Mining only
Esophageal Neoplasms	Esophageal neoplasm	Pubtator	15867347, 16572587, 22213102, 23991974, 25124567, 25436453, 32443386, 34232175	Associate	★☆☆☆☆ Found in Text Mining only
Esophageal Neoplasms	Esophagus Neoplasm	LHGDN	16572587		★☆☆☆☆ Found in Text Mining only
Esophageal Squamous Cell Carcinoma	Esophageal squamous cell carcinoma	Pubtator	19770595, 21470402, 22522455, 24980814, 25124567, 25217103, 25436453, 25924824, 27125974, 32546690, 34232175, 34758762, 37083097, 38043467	Associate	★☆☆☆☆ Found in Text Mining only
Esophagitis	Esotropia	Pubtator	23991974	Associate	★☆☆☆☆ Found in Text Mining only
Exudative age-related macular degeneration	Exudative Macular Degeneration	BEFREE	27832661		★☆☆☆☆ Found in Text Mining only
Familial lichen amyloidosis	Lichen amyloidosis	BEFREE	22389870, 23358695		★☆☆☆☆ Found in Text Mining only
Gastrointestinal Neoplasms	Gastrointestinal neoplasm	Pubtator	18311783, 26778597, 30191522, 31740746	Associate	★☆☆☆☆ Found in Text Mining only
Gastrointestinal Neoplasms	Gastrointestinal Neoplasms	BEFREE	30342037		★☆☆☆☆ Found in Text Mining only
Gastrointestinal Stromal Tumors	Gastrointestinal stromal tumor	BEFREE	16452129, 22167411, 22588468, 30127898		★☆☆☆☆ Found in Text Mining only
Gastrointestinal Stromal Tumors	Gastrointestinal stromal tumor	Pubtator	24901229	Associate	★☆☆☆☆ Found in Text Mining only
Germ cell tumor	Tumor	BEFREE	12813459		★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	20593995, 23761169, 27797168, 28242198, 28989042, 29396807, 31011934, 31706255, 31754113		★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	22160182, 22274399, 23761169, 31754113, 34471141, 35039475, 39528802	Associate	★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	20593995, 23761169, 27797168, 28242198, 28989042, 29396807, 30470262, 31011934, 31706255, 31754113		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	12883693, 23761169, 24879067		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	LHGDN	12883693		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	20529377, 20838435, 22274399, 23761169, 26468983, 30995921, 33892537, 36703644	Associate	★☆☆☆☆ Found in Text Mining only
Glycosuria Renal	Renal glycosuria	Pubtator	30518623	Associate	★☆☆☆☆ Found in Text Mining only
Graft vs Host Disease	Graft-versus-host disease	Pubtator	26606970	Associate	★☆☆☆☆ Found in Text Mining only
Graft-vs-Host Disease	Graft-Vs-Host Disease	BEFREE	26606970, 28077684		★☆☆☆☆ Found in Text Mining only
Head and Neck Carcinoma	Head And Neck Carcinoma	BEFREE	29115879		★☆☆☆☆ Found in Text Mining only
Head and Neck Neoplasms	Head and neck neoplasm	Pubtator	25889801, 33091845	Associate	★☆☆☆☆ Found in Text Mining only
Headache	Headache	Pubtator	37436268	Associate	★☆☆☆☆ Found in Text Mining only
Hepatitis B	Hepatitis b	Pubtator	36077449	Associate	★☆☆☆☆ Found in Text Mining only
Hereditary Breast and Ovarian Cancer Syndrome	Hereditary breast and ovarian cancer syndrome	Pubtator	25830658, 38043467	Associate	★☆☆☆☆ Found in Text Mining only
Hereditary Leiomyomatosis and Renal Cell Cancer	Hereditary Leiomyomatosis and Renal Cancer	BEFREE	24683001		★☆☆☆☆ Found in Text Mining only
Hereditary Nonpolyposis Colorectal Neoplasms	Colorectal Neoplasms	LHGDN	17219423		★☆☆☆☆ Found in Text Mining only
Hyperammonemia	Hyperammonemia	Pubtator	28270654	Associate	★☆☆☆☆ Found in Text Mining only
Hypoxia	Hypoxia	Pubtator	18562694, 22274399, 23966163, 24778030	Stimulate	★☆☆☆☆ Found in Text Mining only
Hypoxia	Hypoxia	Pubtator	28114281	Associate	★☆☆☆☆ Found in Text Mining only
Invasive Ductal Breast Carcinoma	Invasive Duct and Lobular Carcinoma	BEFREE	14693746, 28906374		★☆☆☆☆ Found in Text Mining only
Kidney Neoplasm	Kidney Neoplasm	CTD_human_DG	18497064		★☆☆☆☆ Found in Text Mining only
Kidney Neoplasms	Kidney neoplasm	Pubtator	23151618, 26911844	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Laryngeal Neoplasms	Laryngeal neoplasm	Pubtator	21584819, 36919585	Associate	★☆☆☆☆ Found in Text Mining only
Laryngeal Squamous Cell Carcinoma	Laryngeal Carcinoma	BEFREE	16377583, 21590355, 27356739, 30706572		★☆☆☆☆ Found in Text Mining only
Leukemia	Leukemia	Pubtator	18160664, 18820130, 29477140, 31122263	Associate	★☆☆☆☆ Found in Text Mining only
leukemia	Leukemia	BEFREE	22025529, 27824120, 29477140, 29544896		★☆☆☆☆ Found in Text Mining only
Leukemia Myeloid Acute	Myeloid leukemia	Pubtator	18160664, 20732714, 25887548, 28034990, 31207577	Associate	★☆☆☆☆ Found in Text Mining only
Leukemia, Mast-Cell	Leukemia	BEFREE	24683001		★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	20732714, 22940834, 23101751, 23499911, 23686525, 28034990, 28370201, 29654398, 30266802		★☆☆☆☆ Found in Text Mining only
Lip and Oral Cavity Carcinoma	Lip and Oral Cavity Carcinoma	BEFREE	28152093, 31174434		★☆☆☆☆ Found in Text Mining only
liposarcoma	Liposarcoma	BEFREE	27893412, 31485600		★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	LHGDN	15041727, 18019715		★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	18803637, 19232520, 25284017, 27213815, 28322787, 28903390, 30942456, 31322223, 31570091		★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	CTD_human_DG	28284560		★☆☆☆☆ Found in Text Mining only
Liver Cirrhosis	Liver cirrhosis	Pubtator	37861550	Associate	★☆☆☆☆ Found in Text Mining only
Liver neoplasms	Liver neoplasms	BEFREE	19232520		★☆☆☆☆ Found in Text Mining only
Lung Diseases	Lung disease	Pubtator	21566536	Inhibit	★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung Neoplasms	LHGDN	18043979, 18466087, 18708766		★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	18708766, 21566536, 21718475, 23520446, 25082261, 27713168, 31160567, 31314582, 32469983, 32655004, 32831194, 35178291, 36984548	Associate	★☆☆☆☆ Found in Text Mining only
Lupus Erythematosus Systemic	Systemic lupus erythematosus	Pubtator	31494269	Associate	★☆☆☆☆ Found in Text Mining only
Lupus Nephritis	Lupus Nephritis	BEFREE	30420324, 31066646		★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	19891769, 21584819, 27125974, 32323809	Stimulate	★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	25082261, 25217103, 28404933	Associate	★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic Metastasis	BEFREE	27779297		★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	LHGDN	16080195		★☆☆☆☆ Found in Text Mining only
Lymphoma, Non-Hodgkin	Non-Hodgkin lymphoma	BEFREE	12716366, 21879811		★☆☆☆☆ Found in Text Mining only
Lymphoma, Non-Hodgkin, Familial	Lymphoma	BEFREE	12716366, 21879811		★☆☆☆☆ Found in Text Mining only
Lymphoma, T-Cell, Cutaneous	Lymphoma	BEFREE	25848977		★☆☆☆☆ Found in Text Mining only
Malignant Childhood Neoplasm	Malignant Neoplasm	BEFREE	21448591		★☆☆☆☆ Found in Text Mining only
Malignant Head and Neck Neoplasm	Head and neck cancer	BEFREE	29115879		★☆☆☆☆ Found in Text Mining only
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse	Malignant lymphoma, lymphocytic, intermediate differentiation	BEFREE	24683001		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	11190269, 11259099, 11291073, 12883693, 14693746, 15271853, 15598762, 15688402, 16411056, 16715125, 16762494, 16849685, 17113223, 17627006, 20043089, 20464476, 21412660, 21584498, 21598251, 21630024, 22262870, 22465097, 22752290, 23803310, 23925655, 24349361, 24876664, 25154511, 25169513, 25288231, 25328151, 25667100, 25830658, 25996409, 26782714, 26925658, 27341528, 27461831, 27624071, 28114286, 28187748, 28647900, 28906374, 29863884, 29942081, 30104527, 30180881, 31406104, 9174055		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	CTD_human_DG	18497064		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of endometrium	Endometrial Cancer	BEFREE	27764792		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of esophagus	Esophagus Neoplasm	BEFREE	15867347, 22213102, 24349361, 24953013		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of gastrointestinal tract	Malignant gastrointestinal tract tumors	BEFREE	18311783, 23993973, 26778597, 30191522, 30334109, 30342037		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of kidney	Kidney Cancer	CTD_human_DG	18497064		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of liver	Liver Cancer	BEFREE	12591738, 27213815		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	16792546, 16926177, 17908995, 21718475, 23520446, 25154511, 25882311, 28102363, 30478424		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of mouth	Malignant neoplasm of mouth	BEFREE	28152093, 31174434		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	12417041, 15466974, 15839305, 23787073, 27250762, 28847989		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	12631597, 15078988, 15805292, 16532023, 28167680, 28193222, 28764929, 30844579, 31683659		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	17898866, 18404163, 18802780, 23333597, 23358695, 24631181, 25128228, 27207661, 29396873, 30232224		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	CTD_human_DG	17898866		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of skin	Skin cancer	BEFREE	19738056		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	11259099, 12739007, 16412566, 23993973, 24178904, 26778597, 27121204, 27270838, 28218735, 28843004, 30174615, 30250993, 31521144		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of urinary bladder	Urinary bladder cancer	BEFREE	12208897, 15547700, 17786310, 18361427, 18812553, 23403633, 28102366, 30547784		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	15271853, 15598762, 15802297, 15867347, 16760651, 16951231, 17143471, 17308110, 17627006, 17673924, 17935280, 18404163, 20864688, 21448591, 21718475, 22305495, 22972611, 23328114, 23334327, 23788275, 23925655, 23963861, 24252226, 24349361, 24452445, 24876664, 25124567, 25154511, 27341528, 27624071, 27893412, 28073841, 28167680, 28193222, 28218735, 28322787, 28458622, 28906374, 28915666, 28967900, 29544896, 30190114, 30373917, 30413320, 30547784, 30641296, 30679932, 31617432		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	CGI_DG			★☆☆☆☆ Found in Text Mining only
Malignant Peripheral Nerve Sheath Tumor	Malignant Peripheral Nerve Sheath Tumor	BEFREE	22811580, 23328114, 29473773		★☆☆☆☆ Found in Text Mining only
Malignant Squamous Cell Neoplasm	Neoplasm	BEFREE	31183356		★☆☆☆☆ Found in Text Mining only
Malignant tumor of cervix	Cervical Tumor	BEFREE	21050672, 31706100		★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	19412426, 22311118, 30342037		★☆☆☆☆ Found in Text Mining only
Mammary Carcinoma, Human	Marfan Syndrome	CTD_human_DG	18497064		★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	LHGDN	12833450, 15271853, 15688402, 15944763, 17113223, 17627006, 18628459		★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	BEFREE	14692019, 16715125, 20043089, 21352579, 25169513, 25830658, 9771714		★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	CTD_human_DG	18497064		★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms, Human	Mammary Neoplasms	CTD_human_DG	18497064		★☆☆☆☆ Found in Text Mining only
Mantle cell lymphoma	Mantle Cell Lymphoma	BEFREE	24683001		★☆☆☆☆ Found in Text Mining only
Medulloblastoma	Medulloblastoma	BEFREE	15126347, 27566179		★☆☆☆☆ Found in Text Mining only
Melanoma	Melanoma	Pubtator	16116595, 23362874, 24374110, 25074438, 25444926, 30518564, 31173299, 34673281	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
melanoma	Melanoma	BEFREE	17235240, 24374110, 26152738, 26962685, 27233613, 28188776, 29291012, 31173299		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
melanoma	Melanoma	CTD_human_DG	22535842		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Mesothelioma	Mesothelioma	BEFREE	20371132		★☆☆☆☆ Found in Text Mining only
Mesothelioma Malignant	Mesothelioma	Pubtator	30700254, 33032291	Associate	★☆☆☆☆ Found in Text Mining only
Metastatic melanoma	Metastatic Melanoma	UNIPROT_DG			★☆☆☆☆ Found in Text Mining only
Microcephaly	Microcephaly	BEFREE	28625535		★☆☆☆☆ Found in Text Mining only
Monoclonal Gammopathy of Undetermined Significance	Monoclonal Gammapathies	BEFREE	19652203		★☆☆☆☆ Found in Text Mining only
Mosaic variegated aneuploidy syndrome	Mosaic variegated aneuploidy	Pubtator	25153724	Associate	★☆☆☆☆ Found in Text Mining only
Mouth Neoplasms	Mouth neoplasm	Pubtator	28152093, 28465536, 31174434, 37641028	Associate	★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Multiple myeloma	Pubtator	17213289, 19171872, 19270264, 23411487, 23522059, 32978717	Associate	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Multiple Myeloma	Multiple myeloma	BEFREE	18076711, 19652203, 27857131		★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
MYELODYSPLASTIC SYNDROME	Myelodysplastic Syndrome	BEFREE	23092930, 29220700		★☆☆☆☆ Found in Text Mining only
Myelodysplastic Syndromes	Myelodysplastic syndrome	Pubtator	23092930, 23339595	Associate	★☆☆☆☆ Found in Text Mining only
Myelofibrosis	Myelofibrosis	BEFREE	31061068, 31196854, 31837568		★☆☆☆☆ Found in Text Mining only
Myeloid Leukemia, Chronic	Myeloid Leukemia	BEFREE	27824120, 29387948, 31122263		★☆☆☆☆ Found in Text Mining only
Myeloproliferative disease	Myeloproliferative disorder	BEFREE	31837568		★☆☆☆☆ Found in Text Mining only
Nasopharyngeal Carcinoma	Nasopharyngeal carcinoma	Pubtator	19502819, 22587416	Associate	★☆☆☆☆ Found in Text Mining only
Necrosis	Necrosis	Pubtator	37861550	Associate	★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	11190269, 11259099, 12208897, 12460888, 12631597, 12881723, 14692019, 15126347, 15547718, 15756006, 15805292, 15839305, 15944763, 16715125, 16792546, 16951231, 17003782, 17465238, 17999753, 18311783, 18803637, 19107951, 19232520, 19412426, 19738056, 20043089, 20597069, 20735817, 21718475, 22240781, 22305495, 22588468, 22972611, 23186136, 23328114, 23358695, 23481312, 23788275, 23993973, 24104968, 24163104, 24452445, 24631181, 24841948, 24876664, 24976383, 25124567, 25128228, 25284017, 25328151, 26152738, 26337976, 26486326, 26778597, 27213815, 27233613, 27624071, 27893412, 27923840, 28034990, 28073841, 28242198, 28417568, 28592839, 28595628, 28764929, 28906374, 29138344, 29247383, 29396873, 29845253, 29941483, 30025594, 30342037, 30454901, 30518623, 31134131, 31485600, 31597600, 9771714		★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	19111882, 21731748, 22305495, 23317189, 24439602, 25268132, 26481147, 26616283, 30153557, 30936073, 9771714		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Neuroblastoma	Neuroblastoma	Pubtator	19111882, 19671766, 21731748, 22305495, 23317189, 24439602, 24778030, 25268132, 26481147, 27837025, 30518564, 32757706, 34884931	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Neuroblastoma	Neuroblastoma	CTD_human_DG	22588779		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
neurofibroma	Neurofibroma	BEFREE	22811580		★☆☆☆☆ Found in Text Mining only
Neurofibromatoses	Neurofibromatosis	BEFREE	22811580		★☆☆☆☆ Found in Text Mining only
Neurofibromatosis 1	Neurofibromatosis	BEFREE	22811580		★☆☆☆☆ Found in Text Mining only
Neutropenia	Neutropenia	Pubtator	36892847	Stimulate	★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	21718475, 23053267, 26036635, 26494259, 27435396, 28102363, 28221867, 28378898, 28841389, 28967900, 29363250, 31183356		★☆☆☆☆ Found in Text Mining only
Noninfiltrating Intraductal Carcinoma	Ductal carcinoma	BEFREE	14693746, 27506314		★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	Pubtator	31412932	Associate	★☆☆☆☆ Found in Text Mining only
Oestrogen receptor positive breast cancer	Oestrogen Receptor Positive Breast Cancer	BEFREE	21761347, 29202611		★☆☆☆☆ Found in Text Mining only
oligodendroglioma	Oligodendroglioma	BEFREE	26468983		★☆☆☆☆ Found in Text Mining only
Oligodendroglioma	Oligodendroglioma	Pubtator	26468983	Associate	★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	BEFREE	24129234, 24452445, 26096802		★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	Pubtator	24129234, 32200684	Associate	★☆☆☆☆ Found in Text Mining only
Ovarian clear cell carcinoma	Ovarian Carcinoma	BEFREE	28786875		★☆☆☆☆ Found in Text Mining only
Ovarian Diseases	Ovarian diseases	Pubtator	20423983	Associate	★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	12417041, 15466974, 15839305, 23787073, 27250762		★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	LHGDN	12684414, 15839305, 16894566, 17634535, 17673924		★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	17673924, 18431743, 20423983, 21623171, 22174824, 22895067, 27209210, 28187748, 29122619, 29367628, 29575713, 29693178, 34706741	Associate	★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	34794761	Stimulate	★☆☆☆☆ Found in Text Mining only
Ovarian Serous Adenocarcinoma	Ovarian serous adenocarcinoma	BEFREE	24756216		★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	12631597, 15078988, 15805292, 16532023, 28167680, 28193222, 28764929, 30844579, 31683659		★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasm	Pancreatic Neoplasm	LHGDN	15078988		★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	17505013, 20423983, 28193222	Associate	★☆☆☆☆ Found in Text Mining only
Papilloma	Papilloma	BEFREE	19738056		★☆☆☆☆ Found in Text Mining only
Peripheral Nervous System Diseases	Nervous System Diseases	CTD_human_DG	20864405		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Precursor Cell Lymphoblastic Leukemia Lymphoma	Lymphoblastic Leukemia	BEFREE	24382688		★☆☆☆☆ Found in Text Mining only
Primary Myelofibrosis	Myelofibrosis	BEFREE	31061068, 31196854, 31837568		★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	17898866, 18404163, 18802780, 23333597, 23358695, 24631181, 25128228, 27207661, 29396873, 30232224		★☆☆☆☆ Found in Text Mining only
Prostatic Intraepithelial Neoplasia	Prostatic intraepithelial neoplasia	Pubtator	17898866	Associate	★☆☆☆☆ Found in Text Mining only
Prostatic Intraepithelial Neoplasias	Prostatic Neoplasms	LHGDN	15754349		★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic Neoplasms	CTD_human_DG	17898866		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	17898866, 22389870, 23075505, 23333597, 23358695, 24294372, 25128228, 26425080, 29269934, 29453313, 30232224, 30518564, 33037409, 33630978, 34337875, 34497666, 34625072, 35163398, 36601001, 36834602, 37347559, 37385990	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	35965682	Stimulate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Psoriasis	Psoriasis	BEFREE	21116854		★☆☆☆☆ Found in Text Mining only
Pulmonary Disease Chronic Obstructive	Chronic obstructive pulmonary disease	Pubtator	32655004	Associate	★☆☆☆☆ Found in Text Mining only
Renal Cell Carcinoma	Renal Carcinoma	BEFREE	17143471, 26061684, 29845253, 30518623		★☆☆☆☆ Found in Text Mining only
Respiratory Distress Syndrome, Newborn	Congenital alveolar dysplasia	BEFREE	26507871		★☆☆☆☆ Found in Text Mining only
Rheumatoid Arthritis	Rheumatoid arthritis	BEFREE	17082220		★☆☆☆☆ Found in Text Mining only
Sarcoma	Sarcoma	LHGDN	19074838		★☆☆☆☆ Found in Text Mining only
Sarcoma	Sarcoma	BEFREE	22588468		★☆☆☆☆ Found in Text Mining only
Sarcoma Ewing	Sarcoma	Pubtator	19074838, 36050939	Associate	★☆☆☆☆ Found in Text Mining only
Sarcoma Kaposi	Sarcoma	Pubtator	22396649	Stimulate	★☆☆☆☆ Found in Text Mining only
Sarcopenia	Sarcopenia	Pubtator	38644354	Associate	★☆☆☆☆ Found in Text Mining only
Secondary malignant neoplasm of colon and/or rectum	Colorectal Neoplasms	BEFREE	22240781		★☆☆☆☆ Found in Text Mining only
Seminoma	Seminoma	BEFREE	12813459		★☆☆☆☆ Found in Text Mining only
Skin Neoplasms	Skin Neoplasms	BEFREE	12881723, 19738056		★☆☆☆☆ Found in Text Mining only
Skin Neoplasms	Skin neoplasm	Pubtator	38410032	Associate	★☆☆☆☆ Found in Text Mining only
Small cell carcinoma of lung	Lung carcinoma	BEFREE	24841948, 25128228		★☆☆☆☆ Found in Text Mining only
Small Cell Lung Carcinoma	Small cell lung carcinoma	Pubtator	35263037	Associate	★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma	Carcinoma	LHGDN	15087379		★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma	Carcinoma	BEFREE	16792546, 19738056, 20597069, 23481312, 25124567, 25547434, 31183356		★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of esophagus	Esophagus Neoplasm	BEFREE	15087379, 15756006, 17317845, 23963785, 25124567		★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	19107951, 21584819, 21865609, 23219753, 24810160, 24980817, 25547434, 28152093, 28465536, 33315534, 33892811, 34198450, 36165728, 39323031	Associate	★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of lung	Lung carcinoma	BEFREE	16792546		★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of the head and neck	Carcinoma Of The Head And Neck	BEFREE	16951231, 19107951, 24980817, 30755439		★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	11259099, 12739007, 16412566, 23993973, 24178904, 26778597, 27121204, 27270838, 28218735, 28843004, 30174615, 30250993, 31521144		★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	11259099, 19060929, 22320980, 24439602, 24953013, 25558650, 25609923, 26778597, 27270838, 28260026, 30013101, 30536456, 31521144, 33629578, 34337875, 37839162	Associate	★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach Neoplasms	LHGDN	16412566		★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach Neoplasms	BEFREE	22588468, 23993973		★☆☆☆☆ Found in Text Mining only
Thyroid cancer medullary	Medullary thyroid cancer	Pubtator	24488334	Associate	★☆☆☆☆ Found in Text Mining only
Thyroid Carcinoma Anaplastic	Thyroid cancer	Pubtator	30213925	Associate	★☆☆☆☆ Found in Text Mining only
Thyroid Neoplasms	Thyroid cancer	Pubtator	17914111, 36990998	Associate	★☆☆☆☆ Found in Text Mining only
Tongue Neoplasms	Tongue cancer	Pubtator	19891769	Associate	★☆☆☆☆ Found in Text Mining only
Triple Negative Breast Neoplasms	Triple negative breast cancer	Pubtator	23437271, 31359594, 32558176, 33674749, 36077449, 36372230, 36998242, 37384380	Associate	★☆☆☆☆ Found in Text Mining only
Triple Negative Breast Neoplasms	Triple Negative Breast Neoplasms	BEFREE	30773992, 31134131, 31359594, 31406104		★☆☆☆☆ Found in Text Mining only
Ulcerative Colitis	Ulcerative colitis	BEFREE	26259750		★☆☆☆☆ Found in Text Mining only
Urinary Bladder Neoplasms	Urinary bladder neoplasms	Pubtator	18361427, 18812553, 19389507, 28102366, 34702201, 36245371, 39456780	Associate	★☆☆☆☆ Found in Text Mining only
Urinary Bladder Neoplasms	Urinary bladder neoplasms	Pubtator	30547784, 33217824	Stimulate	★☆☆☆☆ Found in Text Mining only
Urothelial Carcinoma	Urothelial Carcinoma	BEFREE	31597600		★☆☆☆☆ Found in Text Mining only
Uterine Cancer	Endometrial Cancer	BEFREE	17599395		★☆☆☆☆ Found in Text Mining only
Uterine Carcinosarcoma	Endometrial Cancer	BEFREE	27779297		★☆☆☆☆ Found in Text Mining only
Uterine Cervical Dysplasia	Uterine disease	Pubtator	31642613	Associate	★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Uterine neoplasm	Pubtator	19306133, 23052694, 31706100, 32258155, 33967624, 35428744	Associate	★☆☆☆☆ Found in Text Mining only
Uterine Neoplasms	Endometrial Neoplasms	LHGDN	17599395		★☆☆☆☆ Found in Text Mining only
Von Hippel-Lindau Syndrome	Von Hippel-Lindau Syndrome	BEFREE	29845253		★☆☆☆☆ Found in Text Mining only
Waldenstrom Macroglobulinemia	Waldenstrom`s Macroglobulinemia	BEFREE	27825468		★☆☆☆☆ Found in Text Mining only
Well Differentiated Oligodendroglioma	Oligodendroglioma	BEFREE	26468983		★☆☆☆☆ Found in Text Mining only