STATH (statherin)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID 6779
Gene name Statherin
Gene symbol STATH
Synonyms (NCBI Gene)
STR
Chromosome 4
Chromosome location 4q13.3
miRNA miRNA information provided by mirtarbase database.
2
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all (2)
miRTarBase ID miRNA Experiments Reference
MIRT1396087 hsa-miR-3074-3p CLIP-seq
MIRT1396088 hsa-miR-4504 CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
13
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all (13)
GO ID Ontology Definition Evidence Reference
GO:0001503 Process Ossification TAS 1313424
GO:0005515 Function Protein binding IPI 1718282, 16203048, 32296183
GO:0005576 Component Extracellular region IEA
GO:0005576 Component Extracellular region NAS 1718282
GO:0030197 Function Extracellular matrix constituent, lubricant activity NAS 1718282
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
184470 11369 ENSG00000126549
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P02808
Protein name Statherin
Protein function Salivary protein that stabilizes saliva supersaturated with calcium salts by inhibiting the precipitation of calcium phosphate salts. It also modulates hydroxyapatite crystal formation on the tooth surface.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03875 Statherin 20 → 60 Statherin Family
Tissue specificity TISSUE SPECIFICITY: Secreted by parotid and submandibular glands.
Sequence
Sequence length 62
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
  KEGG 
  Salivary secretion  
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (2)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
AUTISTIC DISORDER — CTD, Disgenet
CTD, Disgenet
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
COLOR VISION DISORDER — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Show/Hide Text Mining Associations (54)
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Alzheimer Disease, Early Onset Alzheimer disease BEFREE 7581374
★★★★★
★☆☆☆☆
Found in Text Mining only
AMYOTROPHY, HEREDITARY NEURALGIC Hereditary Neuralgic Amyotrophy BEFREE 10602368, 10610718
★★★★★
★☆☆☆☆
Found in Text Mining only
Anorexia Nervosa Anorexia BEFREE 11912184
★★★★★
★☆☆☆☆
Found in Text Mining only
Antley-Bixler Syndrome with Disordered Steroidogenesis Antley-Bixler Syndrome BEFREE 19621255
★★★★★
★☆☆☆☆
Found in Text Mining only
Asthma Asthma BEFREE 18414509
★★★★★
★☆☆☆☆
Found in Text Mining only
Attention deficit hyperactivity disorder Attention Deficit Hyperactivity Disorder BEFREE 18835330
★★★★★
★☆☆☆☆
Found in Text Mining only
Autistic Disorder Autism CTD_human_DG 19367726
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Autosomal Recessive Polycystic Kidney Disease Polycystic kidney disease BEFREE 20490649
★★★★★
★☆☆☆☆
Found in Text Mining only
Carcinoma Adenoid Cystic Adenoid cystic carcinoma Pubtator 26953815 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Carcinoma of lung Lung carcinoma BEFREE 29154002
★★★★★
★☆☆☆☆
Found in Text Mining only