Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	6728
Gene name	Signal recognition particle 19
Gene symbol	SRP19
Synonyms (NCBI Gene)	-
Chromosome	5
Chromosome location	5q22.2

293

Show/Hide all (293)

miRTarBase ID	miRNA	Experiments	Reference
MIRT031967	hsa-miR-16-5p	Proteomics	18668040
MIRT627530	hsa-miR-6760-5p	HITS-CLIP	19536157
MIRT627529	hsa-miR-1321	HITS-CLIP	19536157
MIRT627528	hsa-miR-4739	HITS-CLIP	19536157
MIRT627527	hsa-miR-4756-5p	HITS-CLIP	19536157
MIRT627526	hsa-miR-6736-3p	HITS-CLIP	19536157
MIRT627525	hsa-miR-4267	HITS-CLIP	19536157
MIRT627520	hsa-miR-3162-5p	HITS-CLIP	19536157
MIRT627519	hsa-miR-7977	HITS-CLIP	19536157
MIRT627518	hsa-miR-5571-3p	HITS-CLIP	19536157
MIRT627516	hsa-miR-665	HITS-CLIP	19536157
MIRT627530	hsa-miR-6760-5p	HITS-CLIP	23824327
MIRT627529	hsa-miR-1321	HITS-CLIP	23824327
MIRT627528	hsa-miR-4739	HITS-CLIP	23824327
MIRT627527	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT627526	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT627525	hsa-miR-4267	HITS-CLIP	23824327
MIRT627524	hsa-miR-5589-3p	HITS-CLIP	23824327
MIRT627520	hsa-miR-3162-5p	HITS-CLIP	23824327
MIRT627518	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT627516	hsa-miR-665	HITS-CLIP	23824327
MIRT675457	hsa-miR-3133	HITS-CLIP	23824327
MIRT675456	hsa-miR-186-5p	HITS-CLIP	23824327
MIRT675455	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT675454	hsa-miR-4493	HITS-CLIP	23824327
MIRT627523	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT627522	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT675453	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT675452	hsa-miR-564	HITS-CLIP	23824327
MIRT675451	hsa-miR-4284	HITS-CLIP	23824327
MIRT675450	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT627519	hsa-miR-7977	HITS-CLIP	23824327
MIRT627517	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT675449	hsa-miR-1-3p	HITS-CLIP	23824327
MIRT627530	hsa-miR-6760-5p	HITS-CLIP	23824327
MIRT627529	hsa-miR-1321	HITS-CLIP	23824327
MIRT627528	hsa-miR-4739	HITS-CLIP	23824327
MIRT627527	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT627526	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT627525	hsa-miR-4267	HITS-CLIP	23824327
MIRT627524	hsa-miR-5589-3p	HITS-CLIP	23824327
MIRT627520	hsa-miR-3162-5p	HITS-CLIP	23824327
MIRT627518	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT627516	hsa-miR-665	HITS-CLIP	23824327
MIRT627530	hsa-miR-6760-5p	HITS-CLIP	23824327
MIRT627529	hsa-miR-1321	HITS-CLIP	23824327
MIRT627528	hsa-miR-4739	HITS-CLIP	23824327
MIRT627527	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT627526	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT627525	hsa-miR-4267	HITS-CLIP	23824327
MIRT627524	hsa-miR-5589-3p	HITS-CLIP	23824327
MIRT627523	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT627522	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT627520	hsa-miR-3162-5p	HITS-CLIP	23824327
MIRT627519	hsa-miR-7977	HITS-CLIP	23824327
MIRT627518	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT627517	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT627516	hsa-miR-665	HITS-CLIP	23824327
MIRT627530	hsa-miR-6760-5p	HITS-CLIP	23824327
MIRT627529	hsa-miR-1321	HITS-CLIP	23824327
MIRT627528	hsa-miR-4739	HITS-CLIP	23824327
MIRT627527	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT627526	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT627525	hsa-miR-4267	HITS-CLIP	23824327
MIRT627524	hsa-miR-5589-3p	HITS-CLIP	23824327
MIRT627523	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT627522	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT627520	hsa-miR-3162-5p	HITS-CLIP	23824327
MIRT627518	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT627517	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT627530	hsa-miR-6760-5p	HITS-CLIP	23824327
MIRT627529	hsa-miR-1321	HITS-CLIP	23824327
MIRT627528	hsa-miR-4739	HITS-CLIP	23824327
MIRT627527	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT627526	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT627525	hsa-miR-4267	HITS-CLIP	23824327
MIRT627520	hsa-miR-3162-5p	HITS-CLIP	23824327
MIRT627519	hsa-miR-7977	HITS-CLIP	23824327
MIRT627518	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT627516	hsa-miR-665	HITS-CLIP	23824327
MIRT627530	hsa-miR-6760-5p	HITS-CLIP	23824327
MIRT627529	hsa-miR-1321	HITS-CLIP	23824327
MIRT627528	hsa-miR-4739	HITS-CLIP	23824327
MIRT627527	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT627526	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT627525	hsa-miR-4267	HITS-CLIP	23824327
MIRT627524	hsa-miR-5589-3p	HITS-CLIP	23824327
MIRT627523	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT627522	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT627520	hsa-miR-3162-5p	HITS-CLIP	23824327
MIRT627519	hsa-miR-7977	HITS-CLIP	23824327
MIRT627518	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT627517	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT627516	hsa-miR-665	HITS-CLIP	23824327
MIRT627530	hsa-miR-6760-5p	HITS-CLIP	23824327
MIRT627529	hsa-miR-1321	HITS-CLIP	23824327
MIRT627528	hsa-miR-4739	HITS-CLIP	23824327
MIRT627527	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT627526	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT627525	hsa-miR-4267	HITS-CLIP	23824327
MIRT627524	hsa-miR-5589-3p	HITS-CLIP	23824327
MIRT627520	hsa-miR-3162-5p	HITS-CLIP	23824327
MIRT627518	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT627516	hsa-miR-665	HITS-CLIP	23824327
MIRT627530	hsa-miR-6760-5p	HITS-CLIP	23824327
MIRT627529	hsa-miR-1321	HITS-CLIP	23824327
MIRT627528	hsa-miR-4739	HITS-CLIP	23824327
MIRT627527	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT627526	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT627525	hsa-miR-4267	HITS-CLIP	23824327
MIRT627524	hsa-miR-5589-3p	HITS-CLIP	23824327
MIRT627523	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT627522	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT627521	hsa-miR-891a-3p	HITS-CLIP	23824327
MIRT627520	hsa-miR-3162-5p	HITS-CLIP	23824327
MIRT627519	hsa-miR-7977	HITS-CLIP	23824327
MIRT627518	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT627517	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT627516	hsa-miR-665	HITS-CLIP	23824327
MIRT627530	hsa-miR-6760-5p	HITS-CLIP	19536157
MIRT627529	hsa-miR-1321	HITS-CLIP	19536157
MIRT627528	hsa-miR-4739	HITS-CLIP	19536157
MIRT627527	hsa-miR-4756-5p	HITS-CLIP	19536157
MIRT627526	hsa-miR-6736-3p	HITS-CLIP	19536157
MIRT627525	hsa-miR-4267	HITS-CLIP	19536157
MIRT627520	hsa-miR-3162-5p	HITS-CLIP	19536157
MIRT627519	hsa-miR-7977	HITS-CLIP	19536157
MIRT627518	hsa-miR-5571-3p	HITS-CLIP	19536157
MIRT627516	hsa-miR-665	HITS-CLIP	19536157
MIRT627530	hsa-miR-6760-5p	HITS-CLIP	23824327
MIRT627529	hsa-miR-1321	HITS-CLIP	23824327
MIRT627528	hsa-miR-4739	HITS-CLIP	23824327
MIRT627527	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT627526	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT627525	hsa-miR-4267	HITS-CLIP	23824327
MIRT627524	hsa-miR-5589-3p	HITS-CLIP	23824327
MIRT627520	hsa-miR-3162-5p	HITS-CLIP	23824327
MIRT627518	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT627516	hsa-miR-665	HITS-CLIP	23824327
MIRT675457	hsa-miR-3133	HITS-CLIP	23824327
MIRT675456	hsa-miR-186-5p	HITS-CLIP	23824327
MIRT675455	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT675454	hsa-miR-4493	HITS-CLIP	23824327
MIRT627523	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT627522	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT675453	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT675452	hsa-miR-564	HITS-CLIP	23824327
MIRT675451	hsa-miR-4284	HITS-CLIP	23824327
MIRT675450	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT627519	hsa-miR-7977	HITS-CLIP	23824327
MIRT627517	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT675449	hsa-miR-1-3p	HITS-CLIP	23824327
MIRT627530	hsa-miR-6760-5p	HITS-CLIP	23824327
MIRT627529	hsa-miR-1321	HITS-CLIP	23824327
MIRT627528	hsa-miR-4739	HITS-CLIP	23824327
MIRT627527	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT627526	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT627525	hsa-miR-4267	HITS-CLIP	23824327
MIRT627524	hsa-miR-5589-3p	HITS-CLIP	23824327
MIRT627520	hsa-miR-3162-5p	HITS-CLIP	23824327
MIRT627518	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT627516	hsa-miR-665	HITS-CLIP	23824327
MIRT627530	hsa-miR-6760-5p	HITS-CLIP	23824327
MIRT627529	hsa-miR-1321	HITS-CLIP	23824327
MIRT627528	hsa-miR-4739	HITS-CLIP	23824327
MIRT627527	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT627526	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT627525	hsa-miR-4267	HITS-CLIP	23824327
MIRT627524	hsa-miR-5589-3p	HITS-CLIP	23824327
MIRT627523	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT627522	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT627520	hsa-miR-3162-5p	HITS-CLIP	23824327
MIRT627519	hsa-miR-7977	HITS-CLIP	23824327
MIRT627518	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT627517	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT627516	hsa-miR-665	HITS-CLIP	23824327
MIRT627530	hsa-miR-6760-5p	HITS-CLIP	23824327
MIRT627529	hsa-miR-1321	HITS-CLIP	23824327
MIRT627528	hsa-miR-4739	HITS-CLIP	23824327
MIRT627527	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT627526	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT627525	hsa-miR-4267	HITS-CLIP	23824327
MIRT627524	hsa-miR-5589-3p	HITS-CLIP	23824327
MIRT627523	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT627522	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT627520	hsa-miR-3162-5p	HITS-CLIP	23824327
MIRT627518	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT627517	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT627530	hsa-miR-6760-5p	HITS-CLIP	23824327
MIRT627529	hsa-miR-1321	HITS-CLIP	23824327
MIRT627528	hsa-miR-4739	HITS-CLIP	23824327
MIRT627527	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT627526	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT627525	hsa-miR-4267	HITS-CLIP	23824327
MIRT627520	hsa-miR-3162-5p	HITS-CLIP	23824327
MIRT627519	hsa-miR-7977	HITS-CLIP	23824327
MIRT627518	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT627516	hsa-miR-665	HITS-CLIP	23824327
MIRT627530	hsa-miR-6760-5p	HITS-CLIP	23824327
MIRT627529	hsa-miR-1321	HITS-CLIP	23824327
MIRT627528	hsa-miR-4739	HITS-CLIP	23824327
MIRT627527	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT627526	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT627525	hsa-miR-4267	HITS-CLIP	23824327
MIRT627524	hsa-miR-5589-3p	HITS-CLIP	23824327
MIRT627523	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT627522	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT627520	hsa-miR-3162-5p	HITS-CLIP	23824327
MIRT627519	hsa-miR-7977	HITS-CLIP	23824327
MIRT627518	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT627517	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT627516	hsa-miR-665	HITS-CLIP	23824327
MIRT627530	hsa-miR-6760-5p	HITS-CLIP	23824327
MIRT627529	hsa-miR-1321	HITS-CLIP	23824327
MIRT627528	hsa-miR-4739	HITS-CLIP	23824327
MIRT627527	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT627526	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT627525	hsa-miR-4267	HITS-CLIP	23824327
MIRT627524	hsa-miR-5589-3p	HITS-CLIP	23824327
MIRT627520	hsa-miR-3162-5p	HITS-CLIP	23824327
MIRT627518	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT627516	hsa-miR-665	HITS-CLIP	23824327
MIRT627530	hsa-miR-6760-5p	HITS-CLIP	23824327
MIRT627529	hsa-miR-1321	HITS-CLIP	23824327
MIRT627528	hsa-miR-4739	HITS-CLIP	23824327
MIRT627527	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT627526	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT627525	hsa-miR-4267	HITS-CLIP	23824327
MIRT627524	hsa-miR-5589-3p	HITS-CLIP	23824327
MIRT627523	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT627522	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT627521	hsa-miR-891a-3p	HITS-CLIP	23824327
MIRT627520	hsa-miR-3162-5p	HITS-CLIP	23824327
MIRT627519	hsa-miR-7977	HITS-CLIP	23824327
MIRT627518	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT627517	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT627516	hsa-miR-665	HITS-CLIP	23824327
MIRT1389170	hsa-miR-1285	CLIP-seq
MIRT1389171	hsa-miR-23a	CLIP-seq
MIRT1389172	hsa-miR-23b	CLIP-seq
MIRT1389173	hsa-miR-23c	CLIP-seq
MIRT1389174	hsa-miR-3187-5p	CLIP-seq
MIRT1389175	hsa-miR-3613-5p	CLIP-seq
MIRT1389176	hsa-miR-3671	CLIP-seq
MIRT1389177	hsa-miR-4520a-3p	CLIP-seq
MIRT1389178	hsa-miR-4520b-3p	CLIP-seq
MIRT1389179	hsa-miR-607	CLIP-seq
MIRT1389180	hsa-miR-612	CLIP-seq
MIRT1389181	hsa-miR-1208	CLIP-seq
MIRT1389182	hsa-miR-1297	CLIP-seq
MIRT1389183	hsa-miR-136	CLIP-seq
MIRT1389184	hsa-miR-203	CLIP-seq
MIRT1389185	hsa-miR-26a	CLIP-seq
MIRT1389186	hsa-miR-26b	CLIP-seq
MIRT1389187	hsa-miR-3171	CLIP-seq
MIRT1389188	hsa-miR-3200-5p	CLIP-seq
MIRT1389189	hsa-miR-3613-3p	CLIP-seq
MIRT1389190	hsa-miR-3647-3p	CLIP-seq
MIRT1389191	hsa-miR-4420	CLIP-seq
MIRT1389192	hsa-miR-4465	CLIP-seq
MIRT1389193	hsa-miR-4495	CLIP-seq
MIRT1389194	hsa-miR-4502	CLIP-seq
MIRT1389195	hsa-miR-4517	CLIP-seq
MIRT1389196	hsa-miR-455-3p	CLIP-seq
MIRT1389197	hsa-miR-4694-3p	CLIP-seq
MIRT1389198	hsa-miR-4699-3p	CLIP-seq
MIRT1389199	hsa-miR-4716-5p	CLIP-seq
MIRT1389200	hsa-miR-4724-5p	CLIP-seq
MIRT1389201	hsa-miR-4762-3p	CLIP-seq
MIRT1389202	hsa-miR-4766-5p	CLIP-seq
MIRT1389203	hsa-miR-494	CLIP-seq
MIRT1389204	hsa-miR-498	CLIP-seq
MIRT1389205	hsa-miR-505	CLIP-seq
MIRT1389206	hsa-miR-513a-3p	CLIP-seq
MIRT1389207	hsa-miR-587	CLIP-seq
MIRT1554157	hsa-miR-4659a-3p	CLIP-seq
MIRT1554158	hsa-miR-4659b-3p	CLIP-seq
MIRT1554159	hsa-miR-942	CLIP-seq
MIRT1389206	hsa-miR-513a-3p	CLIP-seq
MIRT1389181	hsa-miR-1208	CLIP-seq
MIRT1389190	hsa-miR-3647-3p	CLIP-seq
MIRT2339011	hsa-miR-3682-3p	CLIP-seq
MIRT2339012	hsa-miR-4712-3p	CLIP-seq
MIRT1389205	hsa-miR-505	CLIP-seq
MIRT1389170	hsa-miR-1285	CLIP-seq
MIRT1389174	hsa-miR-3187-5p	CLIP-seq
MIRT1389180	hsa-miR-612	CLIP-seq
MIRT2440795	hsa-miR-1283	CLIP-seq
MIRT2440796	hsa-miR-320a	CLIP-seq
MIRT2440797	hsa-miR-320b	CLIP-seq
MIRT2440798	hsa-miR-320c	CLIP-seq
MIRT2440799	hsa-miR-320d	CLIP-seq
MIRT2440800	hsa-miR-4429	CLIP-seq

Show/Hide all (26)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22658674
GO:0003723	Function	RNA binding	IEA
GO:0003723	Function	RNA binding	IPI	17434535
GO:0005515	Function	Protein binding	IPI	24700861, 33961781, 35271311
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IEA
GO:0005730	Component	Nucleolus	IDA	10618370
GO:0005730	Component	Nucleolus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005786	Component	Signal recognition particle, endoplasmic reticulum targeting	IBA
GO:0005786	Component	Signal recognition particle, endoplasmic reticulum targeting	IDA	18089836
GO:0005786	Component	Signal recognition particle, endoplasmic reticulum targeting	IEA
GO:0005786	Component	Signal recognition particle, endoplasmic reticulum targeting	TAS	1678319
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0006613	Process	Cotranslational protein targeting to membrane	TAS	1678319
GO:0006614	Process	SRP-dependent cotranslational protein targeting to membrane	IEA
GO:0006617	Process	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	IBA
GO:0008312	Function	7S RNA binding	IBA
GO:0008312	Function	7S RNA binding	IDA	17434535, 27899666
GO:0008312	Function	7S RNA binding	IEA
GO:0016604	Component	Nuclear body	IDA
GO:0043022	Function	Ribosome binding	IDA	27899666
GO:0048500	Component	Signal recognition particle	IDA	27899666
GO:0048500	Component	Signal recognition particle	IEA
GO:1990904	Component	Ribonucleoprotein complex	IEA

MIM	HGNC	e!Ensembl
182175	11300	ENSG00000153037

P09132

Protein name

Signal recognition particle 19 kDa protein (SRP19)

Protein function

Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity). Binds directly to 7SL RNA (

PDB

1JID , 1MFQ , 1RY1 , 2J37 , 3KTV , 4P3E , 5M73 , 7NFX , 7QWQ

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01922	SRP19	17 → 115	SRP19 protein	Family

Sequence

MACAAARSPADQDRFICIYPAYLNNKKTIAEGRRIPISKAVENPTATEIQDVCSAVGLNV
FLEKNKMYSREWNRDVQYRGRVRVQLKQEDGSLCLVQFPSRKSVMLYAAEMIPKLKTRTQ
KTGGADQSLQQGEGSKKGKGKKKK

Sequence length

144

Interactions

View interactions

	KEGG		Reactome
	Protein export		SRP-dependent cotranslational protein targeting to membrane

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Causal Diseases (2)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Severe congenital neutropenia	Pathogenic	rs1322282571	RCV001199429	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Shwachman-Diamond syndrome 1	Pathogenic	rs1322282571	RCV001199429	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
AUTOSOMAL DOMINANT SEVERE CONGENITAL NEUTROPENIA	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEUTROPENIA	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (5)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adenomatous Polyposis Coli	Multiple polyposis syndrome	BEFREE	1651174		★★★★★ ★☆☆☆☆ Found in Text Mining only
Continuous Muscle Fiber Activity Hereditary	Hereditary continuous muscle fiber activity	Pubtator	27525944	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lupus Erythematosus Systemic	Systemic lupus erythematosus	Pubtator	31494269	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lupus Erythematosus, Systemic	Lupus Erythematosus	BEFREE	31494269		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Diseases	Stomach disease	Pubtator	25210923	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

SRP19 (signal recognition particle 19)