Gene Gene information from NCBI Gene database.
Entrez ID 6726
Gene name Signal recognition particle 9
Gene symbol SRP9
Synonyms (NCBI Gene)
ALURBP
Chromosome 1
Chromosome location 1q42.12
miRNA miRNA information provided by mirtarbase database.
722
miRTarBase ID miRNA Experiments Reference
MIRT029418 hsa-miR-26b-5p Microarray 19088304
MIRT048202 hsa-miR-196a-5p CLASH 23622248
MIRT040748 hsa-miR-18a-3p CLASH 23622248
MIRT039405 hsa-miR-421 CLASH 23622248
MIRT036946 hsa-miR-877-3p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
17
GO ID Ontology Definition Evidence Reference
GO:0003723 Function RNA binding IEA
GO:0003723 Function RNA binding TAS 7730321
GO:0005047 Function Signal recognition particle binding TAS 7730321
GO:0005515 Function Protein binding IPI 11089964, 24965446, 25910212, 28514442, 30021884, 32296183, 32814053, 33961781, 35271311
GO:0005737 Component Cytoplasm IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
600707 11304 ENSG00000143742
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P49458
Protein name Signal recognition particle 9 kDa protein (SRP9)
Protein function Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity). SRP9 together with SRP14 an
PDB 1E8O , 1E8S , 1RY1 , 4UYJ , 4UYK , 5AOX , 7NFX
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05486 SRP9-21 4 73 Signal recognition particle 9 kDa protein (SRP9) Domain
Sequence
Sequence length 86
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Protein export   SRP-dependent cotranslational protein targeting to membrane
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
5
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ENDOMETRIAL CANCER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
ENDOMETRIAL CARCINOMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
ENDOMETRIAL NEOPLASM GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Asthma Asthma GWASDB_DG 21804549
★☆☆☆☆
Found in Text Mining only
Colonic Neoplasms Colonic Neoplasms LHGDN 18549262
★☆☆☆☆
Found in Text Mining only
Colorectal Neoplasms Colorectal neoplasm Pubtator 18549262 Stimulate
★☆☆☆☆
Found in Text Mining only
Colorectal Neoplasms Colorectal neoplasm Pubtator 28161934, 35590292 Associate
★☆☆☆☆
Found in Text Mining only
Liver carcinoma Liver carcinoma BEFREE 17786358, 30664217
★☆☆☆☆
Found in Text Mining only
Liver neoplasms Liver neoplasms BEFREE 30664217
★☆☆☆☆
Found in Text Mining only
Lymphoma Lymphoma Pubtator 33883344 Associate
★☆☆☆☆
Found in Text Mining only