Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
Entrez ID	6689
Gene name	Spi-B transcription factor
Gene symbol	SPIB
Synonyms (NCBI Gene)	SPI-B
Chromosome	19
Chromosome location	19q13.33
Summary	The protein encoded by this gene is a transcriptional activator that binds to the PU-box (5`-GAGGAA-3`) and acts as a lymphoid-specific enhancer. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep

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miRTarBase ID	miRNA	Experiments	Reference
MIRT661108	hsa-miR-3664-5p	HITS-CLIP	23824327
MIRT661107	hsa-miR-6504-3p	HITS-CLIP	23824327
MIRT661106	hsa-miR-4639-3p	HITS-CLIP	23824327
MIRT661105	hsa-miR-5693	HITS-CLIP	23824327
MIRT661104	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT661103	hsa-miR-3135b	HITS-CLIP	23824327
MIRT661102	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT661101	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT661100	hsa-miR-564	HITS-CLIP	23824327
MIRT661098	hsa-miR-3652	HITS-CLIP	23824327
MIRT661099	hsa-miR-4430	HITS-CLIP	23824327
MIRT661097	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT661096	hsa-miR-891a-3p	HITS-CLIP	23824327
MIRT661095	hsa-miR-6794-3p	HITS-CLIP	23824327
MIRT661094	hsa-miR-5698	HITS-CLIP	23824327
MIRT617084	hsa-miR-7161-3p	HITS-CLIP	23824327
MIRT617083	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT617082	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT617079	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT617078	hsa-miR-1248	HITS-CLIP	23824327
MIRT617077	hsa-miR-7113-3p	HITS-CLIP	23824327
MIRT617076	hsa-miR-4287	HITS-CLIP	23824327
MIRT617075	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT617074	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT617073	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT617072	hsa-miR-513a-5p	HITS-CLIP	23824327
MIRT617071	hsa-miR-27a-3p	HITS-CLIP	23824327
MIRT617070	hsa-miR-27b-3p	HITS-CLIP	23824327
MIRT617069	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT617068	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT617066	hsa-miR-6867-3p	HITS-CLIP	23824327
MIRT617065	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT617064	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT617063	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT617062	hsa-miR-5096	HITS-CLIP	23824327
MIRT617061	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT615183	hsa-miR-106a-5p	HITS-CLIP	23824327
MIRT615182	hsa-miR-106b-5p	HITS-CLIP	23824327
MIRT615181	hsa-miR-17-5p	HITS-CLIP	23824327
MIRT615180	hsa-miR-20a-5p	HITS-CLIP	23824327
MIRT615179	hsa-miR-20b-5p	HITS-CLIP	23824327
MIRT615178	hsa-miR-519d-3p	HITS-CLIP	23824327
MIRT615177	hsa-miR-526b-3p	HITS-CLIP	23824327
MIRT615176	hsa-miR-93-5p	HITS-CLIP	23824327
MIRT615175	hsa-miR-302a-3p	HITS-CLIP	23824327
MIRT615174	hsa-miR-302b-3p	HITS-CLIP	23824327
MIRT615173	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT615172	hsa-miR-302d-3p	HITS-CLIP	23824327
MIRT615171	hsa-miR-302e	HITS-CLIP	23824327
MIRT615170	hsa-miR-372-3p	HITS-CLIP	23824327
MIRT615169	hsa-miR-373-3p	HITS-CLIP	23824327
MIRT615168	hsa-miR-520a-3p	HITS-CLIP	23824327
MIRT615167	hsa-miR-520b	HITS-CLIP	23824327
MIRT615166	hsa-miR-520c-3p	HITS-CLIP	23824327
MIRT615165	hsa-miR-520d-3p	HITS-CLIP	23824327
MIRT615164	hsa-miR-520e	HITS-CLIP	23824327
MIRT615163	hsa-miR-512-3p	HITS-CLIP	23824327
MIRT615162	hsa-miR-520g-3p	HITS-CLIP	23824327
MIRT615161	hsa-miR-520h	HITS-CLIP	23824327
MIRT615160	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT615159	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT615158	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT615157	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT615156	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT615183	hsa-miR-106a-5p	HITS-CLIP	23824327
MIRT615182	hsa-miR-106b-5p	HITS-CLIP	23824327
MIRT615181	hsa-miR-17-5p	HITS-CLIP	23824327
MIRT615180	hsa-miR-20a-5p	HITS-CLIP	23824327
MIRT615179	hsa-miR-20b-5p	HITS-CLIP	23824327
MIRT615178	hsa-miR-519d-3p	HITS-CLIP	23824327
MIRT615177	hsa-miR-526b-3p	HITS-CLIP	23824327
MIRT615176	hsa-miR-93-5p	HITS-CLIP	23824327
MIRT615175	hsa-miR-302a-3p	HITS-CLIP	23824327
MIRT615174	hsa-miR-302b-3p	HITS-CLIP	23824327
MIRT615173	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT615172	hsa-miR-302d-3p	HITS-CLIP	23824327
MIRT615171	hsa-miR-302e	HITS-CLIP	23824327
MIRT615170	hsa-miR-372-3p	HITS-CLIP	23824327
MIRT615169	hsa-miR-373-3p	HITS-CLIP	23824327
MIRT615168	hsa-miR-520a-3p	HITS-CLIP	23824327
MIRT615167	hsa-miR-520b	HITS-CLIP	23824327
MIRT615166	hsa-miR-520c-3p	HITS-CLIP	23824327
MIRT615165	hsa-miR-520d-3p	HITS-CLIP	23824327
MIRT615164	hsa-miR-520e	HITS-CLIP	23824327
MIRT615163	hsa-miR-512-3p	HITS-CLIP	23824327
MIRT615162	hsa-miR-520g-3p	HITS-CLIP	23824327
MIRT615161	hsa-miR-520h	HITS-CLIP	23824327
MIRT615160	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT615159	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT615158	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT615157	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT615156	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT617084	hsa-miR-7161-3p	HITS-CLIP	23824327
MIRT617083	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT617082	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT617081	hsa-miR-5193	HITS-CLIP	23824327
MIRT617080	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT617079	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT617078	hsa-miR-1248	HITS-CLIP	23824327
MIRT617077	hsa-miR-7113-3p	HITS-CLIP	23824327
MIRT617076	hsa-miR-4287	HITS-CLIP	23824327
MIRT617075	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT617074	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT617073	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT617072	hsa-miR-513a-5p	HITS-CLIP	23824327
MIRT617071	hsa-miR-27a-3p	HITS-CLIP	23824327
MIRT617070	hsa-miR-27b-3p	HITS-CLIP	23824327
MIRT617069	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT617068	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT617067	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT617066	hsa-miR-6867-3p	HITS-CLIP	23824327
MIRT617065	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT617064	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT617063	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT617062	hsa-miR-5096	HITS-CLIP	23824327
MIRT617061	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT615183	hsa-miR-106a-5p	HITS-CLIP	23824327
MIRT615182	hsa-miR-106b-5p	HITS-CLIP	23824327
MIRT615181	hsa-miR-17-5p	HITS-CLIP	23824327
MIRT615180	hsa-miR-20a-5p	HITS-CLIP	23824327
MIRT615179	hsa-miR-20b-5p	HITS-CLIP	23824327
MIRT615178	hsa-miR-519d-3p	HITS-CLIP	23824327
MIRT615177	hsa-miR-526b-3p	HITS-CLIP	23824327
MIRT615176	hsa-miR-93-5p	HITS-CLIP	23824327
MIRT615175	hsa-miR-302a-3p	HITS-CLIP	23824327
MIRT615174	hsa-miR-302b-3p	HITS-CLIP	23824327
MIRT615173	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT615172	hsa-miR-302d-3p	HITS-CLIP	23824327
MIRT615171	hsa-miR-302e	HITS-CLIP	23824327
MIRT615170	hsa-miR-372-3p	HITS-CLIP	23824327
MIRT615169	hsa-miR-373-3p	HITS-CLIP	23824327
MIRT615168	hsa-miR-520a-3p	HITS-CLIP	23824327
MIRT615167	hsa-miR-520b	HITS-CLIP	23824327
MIRT615166	hsa-miR-520c-3p	HITS-CLIP	23824327
MIRT615165	hsa-miR-520d-3p	HITS-CLIP	23824327
MIRT615164	hsa-miR-520e	HITS-CLIP	23824327
MIRT615163	hsa-miR-512-3p	HITS-CLIP	23824327
MIRT615162	hsa-miR-520g-3p	HITS-CLIP	23824327
MIRT615161	hsa-miR-520h	HITS-CLIP	23824327
MIRT615160	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT615159	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT615158	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT615157	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT615156	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT615157	hsa-miR-150-5p	PAR-CLIP	27292025
MIRT615157	hsa-miR-150-5p	PAR-CLIP	27292025
MIRT615156	hsa-miR-6778-3p	PAR-CLIP	27292025
MIRT615156	hsa-miR-6778-3p	PAR-CLIP	27292025
MIRT615183	hsa-miR-106a-5p	HITS-CLIP	28735896
MIRT615182	hsa-miR-106b-5p	HITS-CLIP	28735896
MIRT615159	hsa-miR-1234-3p	HITS-CLIP	28735896
MIRT615157	hsa-miR-150-5p	HITS-CLIP	28735896
MIRT615181	hsa-miR-17-5p	HITS-CLIP	28735896
MIRT615160	hsa-miR-186-3p	HITS-CLIP	28735896
MIRT615180	hsa-miR-20a-5p	HITS-CLIP	28735896
MIRT615179	hsa-miR-20b-5p	HITS-CLIP	28735896
MIRT615175	hsa-miR-302a-3p	HITS-CLIP	28735896
MIRT615174	hsa-miR-302b-3p	HITS-CLIP	28735896
MIRT615173	hsa-miR-302c-3p	HITS-CLIP	28735896
MIRT615172	hsa-miR-302d-3p	HITS-CLIP	28735896
MIRT615171	hsa-miR-302e	HITS-CLIP	28735896
MIRT615170	hsa-miR-372-3p	HITS-CLIP	28735896
MIRT615169	hsa-miR-373-3p	HITS-CLIP	28735896
MIRT615163	hsa-miR-512-3p	HITS-CLIP	28735896
MIRT615178	hsa-miR-519d-3p	HITS-CLIP	28735896
MIRT615168	hsa-miR-520a-3p	HITS-CLIP	28735896
MIRT615167	hsa-miR-520b	HITS-CLIP	28735896
MIRT615166	hsa-miR-520c-3p	HITS-CLIP	28735896
MIRT615165	hsa-miR-520d-3p	HITS-CLIP	28735896
MIRT615164	hsa-miR-520e	HITS-CLIP	28735896
MIRT615162	hsa-miR-520g-3p	HITS-CLIP	28735896
MIRT615161	hsa-miR-520h	HITS-CLIP	28735896
MIRT615177	hsa-miR-526b-3p	HITS-CLIP	28735896
MIRT615156	hsa-miR-6778-3p	HITS-CLIP	28735896
MIRT615158	hsa-miR-7107-5p	HITS-CLIP	28735896
MIRT615176	hsa-miR-93-5p	HITS-CLIP	28735896
MIRT661108	hsa-miR-3664-5p	HITS-CLIP	23824327
MIRT661107	hsa-miR-6504-3p	HITS-CLIP	23824327
MIRT661106	hsa-miR-4639-3p	HITS-CLIP	23824327
MIRT661105	hsa-miR-5693	HITS-CLIP	23824327
MIRT661104	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT661103	hsa-miR-3135b	HITS-CLIP	23824327
MIRT661102	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT661101	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT661100	hsa-miR-564	HITS-CLIP	23824327
MIRT661098	hsa-miR-3652	HITS-CLIP	23824327
MIRT661099	hsa-miR-4430	HITS-CLIP	23824327
MIRT661097	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT661096	hsa-miR-891a-3p	HITS-CLIP	23824327
MIRT661095	hsa-miR-6794-3p	HITS-CLIP	23824327
MIRT661094	hsa-miR-5698	HITS-CLIP	23824327
MIRT617084	hsa-miR-7161-3p	HITS-CLIP	23824327
MIRT617083	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT617082	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT617079	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT617078	hsa-miR-1248	HITS-CLIP	23824327
MIRT617077	hsa-miR-7113-3p	HITS-CLIP	23824327
MIRT617076	hsa-miR-4287	HITS-CLIP	23824327
MIRT617075	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT617074	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT617073	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT617072	hsa-miR-513a-5p	HITS-CLIP	23824327
MIRT617071	hsa-miR-27a-3p	HITS-CLIP	23824327
MIRT617070	hsa-miR-27b-3p	HITS-CLIP	23824327
MIRT617069	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT617068	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT617066	hsa-miR-6867-3p	HITS-CLIP	23824327
MIRT617065	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT617064	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT617063	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT617062	hsa-miR-5096	HITS-CLIP	23824327
MIRT617061	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT615183	hsa-miR-106a-5p	HITS-CLIP	23824327
MIRT615182	hsa-miR-106b-5p	HITS-CLIP	23824327
MIRT615181	hsa-miR-17-5p	HITS-CLIP	23824327
MIRT615180	hsa-miR-20a-5p	HITS-CLIP	23824327
MIRT615179	hsa-miR-20b-5p	HITS-CLIP	23824327
MIRT615178	hsa-miR-519d-3p	HITS-CLIP	23824327
MIRT615177	hsa-miR-526b-3p	HITS-CLIP	23824327
MIRT615176	hsa-miR-93-5p	HITS-CLIP	23824327
MIRT615175	hsa-miR-302a-3p	HITS-CLIP	23824327
MIRT615174	hsa-miR-302b-3p	HITS-CLIP	23824327
MIRT615173	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT615172	hsa-miR-302d-3p	HITS-CLIP	23824327
MIRT615171	hsa-miR-302e	HITS-CLIP	23824327
MIRT615170	hsa-miR-372-3p	HITS-CLIP	23824327
MIRT615169	hsa-miR-373-3p	HITS-CLIP	23824327
MIRT615168	hsa-miR-520a-3p	HITS-CLIP	23824327
MIRT615167	hsa-miR-520b	HITS-CLIP	23824327
MIRT615166	hsa-miR-520c-3p	HITS-CLIP	23824327
MIRT615165	hsa-miR-520d-3p	HITS-CLIP	23824327
MIRT615164	hsa-miR-520e	HITS-CLIP	23824327
MIRT615163	hsa-miR-512-3p	HITS-CLIP	23824327
MIRT615162	hsa-miR-520g-3p	HITS-CLIP	23824327
MIRT615161	hsa-miR-520h	HITS-CLIP	23824327
MIRT615160	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT615159	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT615158	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT615157	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT615156	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT615183	hsa-miR-106a-5p	HITS-CLIP	23824327
MIRT615182	hsa-miR-106b-5p	HITS-CLIP	23824327
MIRT615181	hsa-miR-17-5p	HITS-CLIP	23824327
MIRT615180	hsa-miR-20a-5p	HITS-CLIP	23824327
MIRT615179	hsa-miR-20b-5p	HITS-CLIP	23824327
MIRT615178	hsa-miR-519d-3p	HITS-CLIP	23824327
MIRT615177	hsa-miR-526b-3p	HITS-CLIP	23824327
MIRT615176	hsa-miR-93-5p	HITS-CLIP	23824327
MIRT615175	hsa-miR-302a-3p	HITS-CLIP	23824327
MIRT615174	hsa-miR-302b-3p	HITS-CLIP	23824327
MIRT615173	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT615172	hsa-miR-302d-3p	HITS-CLIP	23824327
MIRT615171	hsa-miR-302e	HITS-CLIP	23824327
MIRT615170	hsa-miR-372-3p	HITS-CLIP	23824327
MIRT615169	hsa-miR-373-3p	HITS-CLIP	23824327
MIRT615168	hsa-miR-520a-3p	HITS-CLIP	23824327
MIRT615167	hsa-miR-520b	HITS-CLIP	23824327
MIRT615166	hsa-miR-520c-3p	HITS-CLIP	23824327
MIRT615165	hsa-miR-520d-3p	HITS-CLIP	23824327
MIRT615164	hsa-miR-520e	HITS-CLIP	23824327
MIRT615163	hsa-miR-512-3p	HITS-CLIP	23824327
MIRT615162	hsa-miR-520g-3p	HITS-CLIP	23824327
MIRT615161	hsa-miR-520h	HITS-CLIP	23824327
MIRT615160	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT615159	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT615158	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT615157	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT615156	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT617084	hsa-miR-7161-3p	HITS-CLIP	23824327
MIRT617083	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT617082	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT617081	hsa-miR-5193	HITS-CLIP	23824327
MIRT617080	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT617079	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT617078	hsa-miR-1248	HITS-CLIP	23824327
MIRT617077	hsa-miR-7113-3p	HITS-CLIP	23824327
MIRT617076	hsa-miR-4287	HITS-CLIP	23824327
MIRT617075	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT617074	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT617073	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT617072	hsa-miR-513a-5p	HITS-CLIP	23824327
MIRT617071	hsa-miR-27a-3p	HITS-CLIP	23824327
MIRT617070	hsa-miR-27b-3p	HITS-CLIP	23824327
MIRT617069	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT617068	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT617067	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT617066	hsa-miR-6867-3p	HITS-CLIP	23824327
MIRT617065	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT617064	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT617063	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT617062	hsa-miR-5096	HITS-CLIP	23824327
MIRT617061	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT615183	hsa-miR-106a-5p	HITS-CLIP	23824327
MIRT615182	hsa-miR-106b-5p	HITS-CLIP	23824327
MIRT615181	hsa-miR-17-5p	HITS-CLIP	23824327
MIRT615180	hsa-miR-20a-5p	HITS-CLIP	23824327
MIRT615179	hsa-miR-20b-5p	HITS-CLIP	23824327
MIRT615178	hsa-miR-519d-3p	HITS-CLIP	23824327
MIRT615177	hsa-miR-526b-3p	HITS-CLIP	23824327
MIRT615176	hsa-miR-93-5p	HITS-CLIP	23824327
MIRT615175	hsa-miR-302a-3p	HITS-CLIP	23824327
MIRT615174	hsa-miR-302b-3p	HITS-CLIP	23824327
MIRT615173	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT615172	hsa-miR-302d-3p	HITS-CLIP	23824327
MIRT615171	hsa-miR-302e	HITS-CLIP	23824327
MIRT615170	hsa-miR-372-3p	HITS-CLIP	23824327
MIRT615169	hsa-miR-373-3p	HITS-CLIP	23824327
MIRT615168	hsa-miR-520a-3p	HITS-CLIP	23824327
MIRT615167	hsa-miR-520b	HITS-CLIP	23824327
MIRT615166	hsa-miR-520c-3p	HITS-CLIP	23824327
MIRT615165	hsa-miR-520d-3p	HITS-CLIP	23824327
MIRT615164	hsa-miR-520e	HITS-CLIP	23824327
MIRT615163	hsa-miR-512-3p	HITS-CLIP	23824327
MIRT615162	hsa-miR-520g-3p	HITS-CLIP	23824327
MIRT615161	hsa-miR-520h	HITS-CLIP	23824327
MIRT615160	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT615159	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT615158	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT615157	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT615156	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT1383953	hsa-miR-1273f	CLIP-seq
MIRT1383954	hsa-miR-143	CLIP-seq
MIRT1383955	hsa-miR-3200-5p	CLIP-seq
MIRT1383956	hsa-miR-3682-3p	CLIP-seq
MIRT1383957	hsa-miR-4251	CLIP-seq
MIRT1383958	hsa-miR-4329	CLIP-seq
MIRT1383959	hsa-miR-4450	CLIP-seq
MIRT1383960	hsa-miR-4708-5p	CLIP-seq
MIRT1383961	hsa-miR-4770	CLIP-seq
MIRT1383962	hsa-miR-491-5p	CLIP-seq

Show/Hide all (2)

Transcription factor	Regulation	Reference
POU2AF1	Unknown	24801987
POU2F2	Unknown	24801987

Show/Hide all (23)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IMP	10196196
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IMP	10196196
GO:0002327	Process	Immature B cell differentiation	IEA
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0005515	Function	Protein binding	IPI	32814053
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	TAS	8670269
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	TAS	1406622
GO:0030154	Process	Cell differentiation	IBA
GO:0030225	Process	Macrophage differentiation	IEA
GO:0043565	Function	Sequence-specific DNA binding	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IMP	10196196
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

MIM	HGNC	e!Ensembl
606802	11242	ENSG00000269404

Q01892

Protein name

Transcription factor Spi-B

Protein function

Sequence specific transcriptional activator which binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. Promotes development of plasmacytoid dendritic cells (pDCs), also known as type 2 DC p

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00178	Ets	170 → 252	Ets-domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in plasmacytoid dendritic cells (pDCs) and B-cells, not expressed in T-cells or granulocytes. May also be enriched in stem cell populations of the liver. {ECO:0000269|PubMed:11841448, ECO:0000269|PubMed:12393575}.

Sequence

MLALEAAQLDGPHFSCLYPDGVFYDLDSCKHSSYPDSEGAPDSLWDWTVAPPVPATPYEA
FDPAAAAFSHPQAAQLCYEPPTYSPAGNLELAPSLEAPGPGLPAYPTENFASQTLVPPAY
APYPSPVLSEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKKLRLYQFLLGLLT
RGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEI
RKVKRKLTYQFDSALLPAVRRA

Sequence length

262

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (5)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
BILIARY CIRRHOSIS	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BILIARY LIVER CIRRHOSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LIVER CIRRHOSIS, BILIARY	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PRIMARY BILIARY CHOLANGITIS	—	Disgenet, Orphanet Disgenet, Orphanet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PRIMARY BILIARY CIRRHOSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (57)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Acute Erythroblastic Leukemia	Erythroblastic Leukemia	BEFREE	8934542		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adult Diffuse Large B-Cell Lymphoma	B-cell Lymphoma	BEFREE	24875472, 27348272		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adult Hodgkin Lymphoma	Hodgkin Lymphoma	BEFREE	26473286		★★★★★ ★☆☆☆☆ Found in Text Mining only
Autoimmune Diseases	Autoimmune Diseases	BEFREE	22257840		★★★★★ ★☆☆☆☆ Found in Text Mining only
Biliary cirrhosis	Biliary cirrhosis	CTD_human_DG	20639880		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Biliary cirrhosis	Biliary cirrhosis	GWASCAT_DG	20639880, 21399635		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Biliary cirrhosis	Biliary cirrhosis	HPO_DG			★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Biliary Cirrhosis, Primary, 1	Biliary cirrhosis	CTD_human_DG	20639880		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	26099425		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	26099425, 36581948, 37596527, 37684436	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	25070814	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Celiac Disease	Celiac disease	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Cirrhosis	Cirrhosis	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	34841706, 35969172	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Conjugated hyperbilirubinemia	Conjugated hyperbilirubinemia	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Coronary Disease	Coronary artery disease	Pubtator	23539213	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Crohn Disease	Crohn disease	Pubtator	35158099	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Dermatographic urticaria	Dermatographic urticaria	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Diffuse Large B-Cell Lymphoma	Diffuse Lymphoma	BEFREE	24875472, 27348272, 31182435		★★★★★ ★☆☆☆☆ Found in Text Mining only
Fibrosis, Liver	Liver Fibrosis	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Gastrointestinal inflammation	Gastrointestinal inflammation	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Gingivitis	Gingivitis	BEFREE	28393368		★★★★★ ★☆☆☆☆ Found in Text Mining only
Heart Failure	Heart failure	Pubtator	37684436	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hereditary Leiomyomatosis and Renal Cell Cancer	Hereditary Leiomyomatosis and Renal Cancer	BEFREE	29695239		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hodgkin Disease	Hodgkin Disease	BEFREE	26473286		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hodgkin Disease	Hodgkin disease	Pubtator	26473286	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypoalbuminemia	Hypoalbuminemia	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
leukemia	Leukemia	BEFREE	15611260, 30986496		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia	Leukemia	Pubtator	30986496, 36169277	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, Mast-Cell	Leukemia	BEFREE	29695239		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver Cirrhosis Biliary	Liver cirrhosis	Pubtator	20639880, 22257840	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver Failure	Liver failure	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	32129936, 35969172	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphedema	Lymphedema	Pubtator	11841448	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	BEFREE	27348272		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	Pubtator	27348272	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Mantle cell lymphoma	Mantle Cell Lymphoma	BEFREE	29695239		★★★★★ ★☆☆☆☆ Found in Text Mining only
Multiple Sclerosis	Multiple sclerosis	Pubtator	24079660	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	23165482, 28754672		★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteoporosis	Osteoporosis	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	37452634	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Periodontitis	Periodontitis	BEFREE	28393368		★★★★★ ★☆☆☆☆ Found in Text Mining only
Portal Hypertension	Portal Hypertension	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Pre B-cell acute lymphoblastic leukemia	B-cell Lymphoma	BEFREE	30986496		★★★★★ ★☆☆☆☆ Found in Text Mining only
Primary biliary cholangitis	Biliary Cholangitis	Orphanet			★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Primary biliary cirrhosis	Biliary Cirrhosis	GWASDB_DG	20639880, 21399635		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Primary biliary cirrhosis	Biliary Cirrhosis	CTD_human_DG	20639880		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Primary biliary cirrhosis	Biliary Cirrhosis	GWASCAT_DG	20639880, 21399635, 26394269		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Primary biliary cirrhosis	Biliary Cirrhosis	BEFREE	21506939, 22257840		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Primary biliary cirrhosis	Biliary Cirrhosis	ORPHANET_DG			★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Secondary Biliary Cholangitis	Biliary Cholangitis	CTD_human_DG	20639880		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	34599215	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	25070814	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
T-Cell Lymphoma	T-Cell Lymphoma	BEFREE	23165482		★★★★★ ★☆☆☆☆ Found in Text Mining only
Waldenstrom Macroglobulinemia	Waldenstrom`s Macroglobulinemia	BEFREE	24801987		★★★★★ ★☆☆☆☆ Found in Text Mining only
Waldenstrom Macroglobulinemia	Waldenstrom macroglobulinemia	Pubtator	24801987	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

SPIB (Spi-B transcription factor)