Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	6634
Gene name	Small nuclear ribonucleoprotein D3 polypeptide
Gene symbol	SNRPD3
Synonyms (NCBI Gene)	SMD3Sm-D3
Chromosome	22
Chromosome location	22q11.23
Summary	This gene encodes a core component of the spliceosome, which is a nuclear ribonucleoprotein complex that functions in pre-mRNA splicing. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

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Show/Hide all (245)

miRTarBase ID	miRNA	Experiments	Reference
MIRT023211	hsa-miR-124-3p	Proteomics;Microarray	18668037
MIRT024990	hsa-miR-183-5p	Sequencing	20371350
MIRT030561	hsa-miR-24-3p	Microarray	19748357
MIRT044049	hsa-miR-363-3p	CLASH	23622248
MIRT043833	hsa-miR-330-3p	CLASH	23622248
MIRT041313	hsa-miR-193b-3p	CLASH	23622248
MIRT037997	hsa-miR-500a-5p	CLASH	23622248
MIRT720007	hsa-miR-508-5p	HITS-CLIP	19536157
MIRT720006	hsa-miR-6849-3p	HITS-CLIP	19536157
MIRT720005	hsa-miR-939-3p	HITS-CLIP	19536157
MIRT720004	hsa-miR-766-3p	HITS-CLIP	19536157
MIRT720003	hsa-miR-1285-3p	HITS-CLIP	19536157
MIRT720002	hsa-miR-3187-5p	HITS-CLIP	19536157
MIRT720001	hsa-miR-5189-5p	HITS-CLIP	19536157
MIRT720000	hsa-miR-612	HITS-CLIP	19536157
MIRT719999	hsa-miR-6860	HITS-CLIP	19536157
MIRT719998	hsa-miR-4738-3p	HITS-CLIP	19536157
MIRT719997	hsa-miR-661	HITS-CLIP	19536157
MIRT719996	hsa-miR-196a-3p	HITS-CLIP	19536157
MIRT719995	hsa-miR-6512-3p	HITS-CLIP	19536157
MIRT719994	hsa-miR-6720-5p	HITS-CLIP	19536157
MIRT699100	hsa-miR-3714	HITS-CLIP	23313552
MIRT699099	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT699098	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT699097	hsa-miR-940	HITS-CLIP	23313552
MIRT699096	hsa-miR-383-3p	HITS-CLIP	23313552
MIRT699095	hsa-miR-3665	HITS-CLIP	23313552
MIRT699094	hsa-miR-4736	HITS-CLIP	23313552
MIRT699093	hsa-miR-7106-5p	HITS-CLIP	23313552
MIRT699092	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT699091	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT699090	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT699089	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT699088	hsa-miR-6799-5p	HITS-CLIP	23313552
MIRT699087	hsa-miR-3165	HITS-CLIP	23313552
MIRT628981	hsa-miR-7977	HITS-CLIP	23313552
MIRT699086	hsa-miR-30c-1-3p	HITS-CLIP	23313552
MIRT699085	hsa-miR-30c-2-3p	HITS-CLIP	23313552
MIRT699084	hsa-miR-6788-5p	HITS-CLIP	23313552
MIRT699083	hsa-miR-1273h-5p	HITS-CLIP	23313552
MIRT699082	hsa-miR-30b-3p	HITS-CLIP	23313552
MIRT699081	hsa-miR-3689a-3p	HITS-CLIP	23313552
MIRT699080	hsa-miR-3689b-3p	HITS-CLIP	23313552
MIRT699079	hsa-miR-3689c	HITS-CLIP	23313552
MIRT699078	hsa-miR-6779-5p	HITS-CLIP	23313552
MIRT699077	hsa-miR-6780a-5p	HITS-CLIP	23313552
MIRT699076	hsa-miR-450a-1-3p	HITS-CLIP	23313552
MIRT699075	hsa-miR-3122	HITS-CLIP	23313552
MIRT699074	hsa-miR-3913-5p	HITS-CLIP	23313552
MIRT699073	hsa-miR-887-5p	HITS-CLIP	23313552
MIRT699072	hsa-miR-6513-5p	HITS-CLIP	23313552
MIRT628985	hsa-miR-6749-5p	HITS-CLIP	23824327
MIRT628984	hsa-miR-4456	HITS-CLIP	23824327
MIRT628983	hsa-miR-4284	HITS-CLIP	23824327
MIRT030561	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT628982	hsa-miR-2861	HITS-CLIP	23824327
MIRT628981	hsa-miR-7977	HITS-CLIP	23824327
MIRT564534	hsa-miR-501-3p	PAR-CLIP	20371350
MIRT564533	hsa-miR-502-3p	PAR-CLIP	20371350
MIRT564532	hsa-miR-548aj-5p	PAR-CLIP	20371350
MIRT564531	hsa-miR-548f-5p	PAR-CLIP	20371350
MIRT564530	hsa-miR-548g-5p	PAR-CLIP	20371350
MIRT564529	hsa-miR-548x-5p	PAR-CLIP	20371350
MIRT564528	hsa-miR-4470	PAR-CLIP	20371350
MIRT545739	hsa-miR-142-5p	PAR-CLIP	21572407
MIRT545736	hsa-miR-5590-3p	PAR-CLIP	21572407
MIRT545737	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT545734	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT545735	hsa-miR-454-5p	PAR-CLIP	21572407
MIRT545733	hsa-miR-340-5p	PAR-CLIP	21572407
MIRT545732	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT545731	hsa-miR-6883-3p	PAR-CLIP	21572407
MIRT532721	hsa-miR-4418	PAR-CLIP	22012620
MIRT532720	hsa-miR-509-3-5p	PAR-CLIP	22012620
MIRT532719	hsa-miR-509-5p	PAR-CLIP	22012620
MIRT532718	hsa-miR-1306-5p	PAR-CLIP	22012620
MIRT532717	hsa-miR-6890-3p	PAR-CLIP	22012620
MIRT532716	hsa-miR-3155a	PAR-CLIP	22012620
MIRT532715	hsa-miR-3155b	PAR-CLIP	22012620
MIRT532714	hsa-miR-484	PAR-CLIP	22012620
MIRT532713	hsa-miR-1247-3p	PAR-CLIP	22012620
MIRT532712	hsa-miR-4532	PAR-CLIP	22012620
MIRT532711	hsa-miR-1205	PAR-CLIP	22012620
MIRT532710	hsa-miR-1206	PAR-CLIP	22012620
MIRT532709	hsa-miR-6511b-5p	PAR-CLIP	22012620
MIRT532708	hsa-miR-6811-5p	PAR-CLIP	22012620
MIRT462700	hsa-miR-490-3p	PAR-CLIP	23592263
MIRT462699	hsa-miR-649	PAR-CLIP	23592263
MIRT462698	hsa-miR-8080	PAR-CLIP	23592263
MIRT462697	hsa-miR-4330	PAR-CLIP	23592263
MIRT462696	hsa-miR-4766-5p	PAR-CLIP	23592263
MIRT462695	hsa-miR-4680-5p	PAR-CLIP	23592263
MIRT462694	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT462693	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT462692	hsa-miR-4459	PAR-CLIP	23592263
MIRT462691	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT462690	hsa-miR-6077	PAR-CLIP	23592263
MIRT462689	hsa-miR-766-5p	PAR-CLIP	23592263
MIRT462688	hsa-miR-4743-5p	PAR-CLIP	23592263
MIRT462687	hsa-miR-6721-5p	PAR-CLIP	23592263
MIRT462686	hsa-miR-541-3p	PAR-CLIP	23592263
MIRT462685	hsa-miR-654-5p	PAR-CLIP	23592263
MIRT462684	hsa-miR-6774-5p	PAR-CLIP	23592263
MIRT442672	hsa-miR-6858-3p	PAR-CLIP	22100165
MIRT442671	hsa-miR-4676-5p	PAR-CLIP	22100165
MIRT442670	hsa-miR-575	PAR-CLIP	22100165
MIRT442669	hsa-miR-6830-5p	PAR-CLIP	22100165
MIRT442668	hsa-let-7d-3p	PAR-CLIP	22100165
MIRT439575	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT439575	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT720007	hsa-miR-508-5p	HITS-CLIP	19536157
MIRT720006	hsa-miR-6849-3p	HITS-CLIP	19536157
MIRT720005	hsa-miR-939-3p	HITS-CLIP	19536157
MIRT720004	hsa-miR-766-3p	HITS-CLIP	19536157
MIRT720003	hsa-miR-1285-3p	HITS-CLIP	19536157
MIRT720002	hsa-miR-3187-5p	HITS-CLIP	19536157
MIRT720001	hsa-miR-5189-5p	HITS-CLIP	19536157
MIRT720000	hsa-miR-612	HITS-CLIP	19536157
MIRT719999	hsa-miR-6860	HITS-CLIP	19536157
MIRT719998	hsa-miR-4738-3p	HITS-CLIP	19536157
MIRT719997	hsa-miR-661	HITS-CLIP	19536157
MIRT719996	hsa-miR-196a-3p	HITS-CLIP	19536157
MIRT719995	hsa-miR-6512-3p	HITS-CLIP	19536157
MIRT719994	hsa-miR-6720-5p	HITS-CLIP	19536157
MIRT699100	hsa-miR-3714	HITS-CLIP	23313552
MIRT699099	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT699098	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT699097	hsa-miR-940	HITS-CLIP	23313552
MIRT699096	hsa-miR-383-3p	HITS-CLIP	23313552
MIRT699095	hsa-miR-3665	HITS-CLIP	23313552
MIRT699094	hsa-miR-4736	HITS-CLIP	23313552
MIRT699093	hsa-miR-7106-5p	HITS-CLIP	23313552
MIRT699092	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT699091	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT699090	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT699089	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT699088	hsa-miR-6799-5p	HITS-CLIP	23313552
MIRT699087	hsa-miR-3165	HITS-CLIP	23313552
MIRT628981	hsa-miR-7977	HITS-CLIP	23313552
MIRT699086	hsa-miR-30c-1-3p	HITS-CLIP	23313552
MIRT699085	hsa-miR-30c-2-3p	HITS-CLIP	23313552
MIRT699084	hsa-miR-6788-5p	HITS-CLIP	23313552
MIRT699083	hsa-miR-1273h-5p	HITS-CLIP	23313552
MIRT699082	hsa-miR-30b-3p	HITS-CLIP	23313552
MIRT699081	hsa-miR-3689a-3p	HITS-CLIP	23313552
MIRT699080	hsa-miR-3689b-3p	HITS-CLIP	23313552
MIRT699079	hsa-miR-3689c	HITS-CLIP	23313552
MIRT699078	hsa-miR-6779-5p	HITS-CLIP	23313552
MIRT699077	hsa-miR-6780a-5p	HITS-CLIP	23313552
MIRT699076	hsa-miR-450a-1-3p	HITS-CLIP	23313552
MIRT699075	hsa-miR-3122	HITS-CLIP	23313552
MIRT699074	hsa-miR-3913-5p	HITS-CLIP	23313552
MIRT699073	hsa-miR-887-5p	HITS-CLIP	23313552
MIRT699072	hsa-miR-6513-5p	HITS-CLIP	23313552
MIRT628985	hsa-miR-6749-5p	HITS-CLIP	23824327
MIRT628984	hsa-miR-4456	HITS-CLIP	23824327
MIRT628983	hsa-miR-4284	HITS-CLIP	23824327
MIRT030561	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT628982	hsa-miR-2861	HITS-CLIP	23824327
MIRT628981	hsa-miR-7977	HITS-CLIP	23824327
MIRT564534	hsa-miR-501-3p	PAR-CLIP	20371350
MIRT564533	hsa-miR-502-3p	PAR-CLIP	20371350
MIRT564532	hsa-miR-548aj-5p	PAR-CLIP	20371350
MIRT564531	hsa-miR-548f-5p	PAR-CLIP	20371350
MIRT564530	hsa-miR-548g-5p	PAR-CLIP	20371350
MIRT564529	hsa-miR-548x-5p	PAR-CLIP	20371350
MIRT564528	hsa-miR-4470	PAR-CLIP	20371350
MIRT545739	hsa-miR-142-5p	PAR-CLIP	21572407
MIRT545736	hsa-miR-5590-3p	PAR-CLIP	21572407
MIRT545737	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT545734	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT545735	hsa-miR-454-5p	PAR-CLIP	21572407
MIRT545733	hsa-miR-340-5p	PAR-CLIP	21572407
MIRT545732	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT545731	hsa-miR-6883-3p	PAR-CLIP	21572407
MIRT532721	hsa-miR-4418	PAR-CLIP	22012620
MIRT532720	hsa-miR-509-3-5p	PAR-CLIP	22012620
MIRT532719	hsa-miR-509-5p	PAR-CLIP	22012620
MIRT532718	hsa-miR-1306-5p	PAR-CLIP	22012620
MIRT532717	hsa-miR-6890-3p	PAR-CLIP	22012620
MIRT532716	hsa-miR-3155a	PAR-CLIP	22012620
MIRT532715	hsa-miR-3155b	PAR-CLIP	22012620
MIRT532714	hsa-miR-484	PAR-CLIP	22012620
MIRT532713	hsa-miR-1247-3p	PAR-CLIP	22012620
MIRT532712	hsa-miR-4532	PAR-CLIP	22012620
MIRT532711	hsa-miR-1205	PAR-CLIP	22012620
MIRT532710	hsa-miR-1206	PAR-CLIP	22012620
MIRT532709	hsa-miR-6511b-5p	PAR-CLIP	22012620
MIRT532708	hsa-miR-6811-5p	PAR-CLIP	22012620
MIRT462700	hsa-miR-490-3p	PAR-CLIP	23592263
MIRT462699	hsa-miR-649	PAR-CLIP	23592263
MIRT462698	hsa-miR-8080	PAR-CLIP	23592263
MIRT462697	hsa-miR-4330	PAR-CLIP	23592263
MIRT462696	hsa-miR-4766-5p	PAR-CLIP	23592263
MIRT462695	hsa-miR-4680-5p	PAR-CLIP	23592263
MIRT462694	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT462693	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT462692	hsa-miR-4459	PAR-CLIP	23592263
MIRT462691	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT462690	hsa-miR-6077	PAR-CLIP	23592263
MIRT462689	hsa-miR-766-5p	PAR-CLIP	23592263
MIRT462688	hsa-miR-4743-5p	PAR-CLIP	23592263
MIRT462687	hsa-miR-6721-5p	PAR-CLIP	23592263
MIRT462686	hsa-miR-541-3p	PAR-CLIP	23592263
MIRT462685	hsa-miR-654-5p	PAR-CLIP	23592263
MIRT462684	hsa-miR-6774-5p	PAR-CLIP	23592263
MIRT442672	hsa-miR-6858-3p	PAR-CLIP	22100165
MIRT442671	hsa-miR-4676-5p	PAR-CLIP	22100165
MIRT442670	hsa-miR-575	PAR-CLIP	22100165
MIRT442669	hsa-miR-6830-5p	PAR-CLIP	22100165
MIRT442668	hsa-let-7d-3p	PAR-CLIP	22100165
MIRT1376231	hsa-miR-2117	CLIP-seq
MIRT1376232	hsa-miR-3917	CLIP-seq
MIRT1376233	hsa-miR-4273	CLIP-seq
MIRT1376234	hsa-miR-4761-5p	CLIP-seq
MIRT1376235	hsa-miR-515-5p	CLIP-seq
MIRT2111854	hsa-miR-216a	CLIP-seq
MIRT2111855	hsa-miR-4668-3p	CLIP-seq
MIRT2335145	hsa-miR-105	CLIP-seq
MIRT2335146	hsa-miR-1256	CLIP-seq
MIRT2335147	hsa-miR-1278	CLIP-seq
MIRT2335148	hsa-miR-150	CLIP-seq
MIRT2335149	hsa-miR-1915	CLIP-seq
MIRT2335150	hsa-miR-193a-3p	CLIP-seq
MIRT2335151	hsa-miR-193b	CLIP-seq
MIRT2335152	hsa-miR-21	CLIP-seq
MIRT2335153	hsa-miR-3145-5p	CLIP-seq
MIRT2335154	hsa-miR-331-3p	CLIP-seq
MIRT2335155	hsa-miR-361-3p	CLIP-seq
MIRT2335156	hsa-miR-3646	CLIP-seq
MIRT2335157	hsa-miR-3671	CLIP-seq
MIRT2335158	hsa-miR-3679-3p	CLIP-seq
MIRT2335159	hsa-miR-3973	CLIP-seq
MIRT2335160	hsa-miR-4436a	CLIP-seq
MIRT2335161	hsa-miR-4713-5p	CLIP-seq
MIRT2335162	hsa-miR-4720-5p	CLIP-seq
MIRT2335163	hsa-miR-4726-3p	CLIP-seq
MIRT2335164	hsa-miR-4799-3p	CLIP-seq
MIRT2335165	hsa-miR-520g	CLIP-seq
MIRT2335166	hsa-miR-520h	CLIP-seq
MIRT2335167	hsa-miR-532-3p	CLIP-seq
MIRT2335168	hsa-miR-548k	CLIP-seq
MIRT2335169	hsa-miR-590-5p	CLIP-seq
MIRT2335170	hsa-miR-607	CLIP-seq
MIRT2335171	hsa-miR-892b	CLIP-seq

Show/Hide all (67)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000243	Component	Commitment complex	IBA
GO:0000387	Process	Spliceosomal snRNP assembly	IBA
GO:0000387	Process	Spliceosomal snRNP assembly	IDA	18984161
GO:0000387	Process	Spliceosomal snRNP assembly	IEA
GO:0000398	Process	MRNA splicing, via spliceosome	IC	11991638
GO:0000398	Process	MRNA splicing, via spliceosome	IDA	28076346, 32494006, 36797247
GO:0000398	Process	MRNA splicing, via spliceosome	NAS	15564372, 30975767, 31744343, 33677607
GO:0003723	Function	RNA binding	HDA	22681889
GO:0003723	Function	RNA binding	IBA
GO:0003723	Function	RNA binding	IEA
GO:0003723	Function	RNA binding	IPI	18082603
GO:0005515	Function	Protein binding	IPI	10500148, 11714716, 11748230, 12065586, 15231747, 17332742, 18984161, 19325628, 21988832, 22101937, 22365833, 23236152, 30021884, 32296183, 32814053, 33961781, 35271311, 37248947
GO:0005634	Component	Nucleus	IDA	28076346
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	NAS	21113136, 30975767, 31744343
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005681	Component	Spliceosomal complex	IEA
GO:0005681	Component	Spliceosomal complex	IPI	30975767, 33677607
GO:0005681	Component	Spliceosomal complex	NAS	31744343
GO:0005681	Component	Spliceosomal complex	TAS	7527560
GO:0005682	Component	U5 snRNP	IBA
GO:0005682	Component	U5 snRNP	NAS	15564372
GO:0005683	Component	U7 snRNP	IDA	11574479
GO:0005684	Component	U2-type spliceosomal complex	IDA	32494006, 36797247
GO:0005685	Component	U1 snRNP	IBA
GO:0005685	Component	U1 snRNP	IDA	21113136, 25555158
GO:0005685	Component	U1 snRNP	IPI	33677607
GO:0005685	Component	U1 snRNP	NAS	15564372
GO:0005686	Component	U2 snRNP	IBA
GO:0005686	Component	U2 snRNP	NAS	15564372, 31744343
GO:0005687	Component	U4 snRNP	IBA
GO:0005687	Component	U4 snRNP	IDA	21516107
GO:0005687	Component	U4 snRNP	NAS	15564372
GO:0005689	Component	U12-type spliceosomal complex	IDA	15146077
GO:0005697	Component	Telomerase holoenzyme complex	IDA	18082603
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA	18984161
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006396	Process	RNA processing	IEA
GO:0006397	Process	MRNA processing	IEA
GO:0006479	Process	Protein methylation	IDA	18495660
GO:0008380	Process	RNA splicing	IEA
GO:0008380	Process	RNA splicing	TAS	1701240
GO:0016604	Component	Nuclear body	IDA
GO:0019899	Function	Enzyme binding	IPI	17709427
GO:0030532	Component	Small nuclear ribonucleoprotein complex	TAS	1701240
GO:0034709	Component	Methylosome	IDA	18984161
GO:0034715	Component	PICln-Sm protein complex	IDA	18984161
GO:0034719	Component	SMN-Sm protein complex	IBA
GO:0034719	Component	SMN-Sm protein complex	IDA	18984161
GO:0036261	Process	7-methylguanosine cap hypermethylation	NAS	15564372
GO:0046540	Component	U4/U6 x U5 tri-snRNP complex	IDA	26912367
GO:0046540	Component	U4/U6 x U5 tri-snRNP complex	IPI	30975767
GO:0070034	Function	Telomerase RNA binding	IPI	18082603
GO:0071005	Component	U2-type precatalytic spliceosome	IDA	28781166
GO:0071007	Component	U2-type catalytic step 2 spliceosome	IDA	28076346
GO:0071011	Component	Precatalytic spliceosome	IBA
GO:0071013	Component	Catalytic step 2 spliceosome	IBA
GO:0071013	Component	Catalytic step 2 spliceosome	IDA	11991638
GO:0071208	Function	Histone pre-mRNA DCP binding	IEA
GO:0071208	Function	Histone pre-mRNA DCP binding	ISS
GO:0071209	Function	U7 snRNA binding	IPI	18082603
GO:0097526	Component	Spliceosomal tri-snRNP complex	IBA
GO:1903241	Process	U2-type prespliceosome assembly	NAS	31744343
GO:1990904	Component	Ribonucleoprotein complex	IEA

MIM	HGNC	e!Ensembl
601062	11160	ENSG00000100028

P62318

Protein name

Small nuclear ribonucleoprotein Sm D3 (Sm-D3) (snRNP core protein D3)

Protein function

Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:25555158, Pu

PDB

1D3B , 3CW1 , 3JCR , 3PGW , 3VRI , 4PJO , 4WZJ , 5MQF , 5O9Z , 5XJC , 5YZG , 5Z56 , 5Z57 , 5Z58 , 6AH0 , 6AHD , 6FF7 , 6ICZ , 6ID0 , 6ID1 , 6QDV , 6QW6 , 6QX9 , 6V4X , 6Y53 , 6Y5Q , 7A5P , 7ABG , 7ABI , 7B0Y , 7DVQ , 7EVO , 7QTT , 7VPX , 7W59 , 7W5A , 7W5B , 8C6J , 8CH6 , 8H6E , 8H6J , 8H6K , 8H6L , 8HK1 , 8I0P , 8I0R , 8I0S , 8I0T , 8I0U , 8I0V , 8I0W

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01423	LSM	8 → 73	LSM domain	Domain

Sequence

MSIGVPIKVLHEAEGHIVTCETNTGEVYRGKLIEAEDNMNCQMSNITVTYRDGRVAQLEQ
VYIRGSKIRFLILPDMLKNAPMLKSMKNKNQGSGAGRGKAAILKAQVAARGRGRGMGRGN
IFQKRR

Sequence length

126

Interactions

View interactions

	KEGG		Reactome
	Spliceosome Systemic lupus erythematosus		SLBP independent Processing of Histone Pre-mRNAs snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
CARCINOMA	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUPUS ERYTHEMATOSUS, SYSTEMIC	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (11)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Anaplastic carcinoma	Anaplastic Carcinoma	CTD_human_DG	16316942		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	38049564	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	CTD_human_DG	16316942		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Carcinoma of lung	Lung carcinoma	BEFREE	28806746		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma, Spindle-Cell	Carcinoma	CTD_human_DG	16316942		★★★★★ ★☆☆☆☆ Found in Text Mining only
Huntington Disease	Huntington disease	Pubtator	33049985	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lupus Erythematosus Systemic	Systemic lupus erythematosus	Pubtator	22363785	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	28806746		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	Pubtator	38049564	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	28296343		★★★★★ ★☆☆☆☆ Found in Text Mining only
Undifferentiated carcinoma	Carcinoma	CTD_human_DG	16316942		★★★★★ ★☆☆☆☆ Found in Text Mining only

SNRPD3 (small nuclear ribonucleoprotein D3 polypeptide)