Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	66035
Gene name	Solute carrier family 2 member 11
Gene symbol	SLC2A11
Synonyms (NCBI Gene)	GLUT10GLUT11
Chromosome	22
Chromosome location	22q11.23
Summary	This gene belongs to a family of proteins that mediate the transport of sugars across the cell membrane. The encoded protein transports glucose and fructose. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

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Show/Hide all (228)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018382	hsa-miR-335-5p	Microarray	18185580
MIRT051456	hsa-let-7e-5p	CLASH	23622248
MIRT714004	hsa-miR-649	HITS-CLIP	19536157
MIRT714003	hsa-miR-6890-3p	HITS-CLIP	19536157
MIRT714002	hsa-miR-4742-3p	HITS-CLIP	19536157
MIRT714001	hsa-miR-5189-3p	HITS-CLIP	19536157
MIRT714000	hsa-miR-181b-2-3p	HITS-CLIP	19536157
MIRT713999	hsa-miR-181b-3p	HITS-CLIP	19536157
MIRT713998	hsa-miR-4420	HITS-CLIP	19536157
MIRT713997	hsa-miR-653-3p	HITS-CLIP	19536157
MIRT713996	hsa-miR-3606-3p	HITS-CLIP	19536157
MIRT714004	hsa-miR-649	HITS-CLIP	19536157
MIRT714003	hsa-miR-6890-3p	HITS-CLIP	19536157
MIRT714002	hsa-miR-4742-3p	HITS-CLIP	19536157
MIRT714001	hsa-miR-5189-3p	HITS-CLIP	19536157
MIRT714000	hsa-miR-181b-2-3p	HITS-CLIP	19536157
MIRT713999	hsa-miR-181b-3p	HITS-CLIP	19536157
MIRT713998	hsa-miR-4420	HITS-CLIP	19536157
MIRT713997	hsa-miR-653-3p	HITS-CLIP	19536157
MIRT713996	hsa-miR-3606-3p	HITS-CLIP	19536157
MIRT714004	hsa-miR-649	HITS-CLIP	19536157
MIRT714003	hsa-miR-6890-3p	HITS-CLIP	19536157
MIRT714002	hsa-miR-4742-3p	HITS-CLIP	19536157
MIRT714001	hsa-miR-5189-3p	HITS-CLIP	19536157
MIRT714000	hsa-miR-181b-2-3p	HITS-CLIP	19536157
MIRT713999	hsa-miR-181b-3p	HITS-CLIP	19536157
MIRT713998	hsa-miR-4420	HITS-CLIP	19536157
MIRT713997	hsa-miR-653-3p	HITS-CLIP	19536157
MIRT713996	hsa-miR-3606-3p	HITS-CLIP	19536157
MIRT684677	hsa-miR-4438	HITS-CLIP	23313552
MIRT684676	hsa-miR-6504-3p	HITS-CLIP	23313552
MIRT684675	hsa-miR-3622a-3p	HITS-CLIP	23313552
MIRT684674	hsa-miR-3622b-3p	HITS-CLIP	23313552
MIRT684673	hsa-miR-6765-3p	HITS-CLIP	23313552
MIRT684672	hsa-miR-4691-3p	HITS-CLIP	23313552
MIRT684671	hsa-miR-4711-5p	HITS-CLIP	23313552
MIRT684670	hsa-miR-5095	HITS-CLIP	23313552
MIRT684669	hsa-miR-7151-3p	HITS-CLIP	23313552
MIRT684668	hsa-miR-3157-5p	HITS-CLIP	23313552
MIRT714004	hsa-miR-649	HITS-CLIP	19536157
MIRT714003	hsa-miR-6890-3p	HITS-CLIP	19536157
MIRT714002	hsa-miR-4742-3p	HITS-CLIP	19536157
MIRT714001	hsa-miR-5189-3p	HITS-CLIP	19536157
MIRT714000	hsa-miR-181b-2-3p	HITS-CLIP	19536157
MIRT713999	hsa-miR-181b-3p	HITS-CLIP	19536157
MIRT713998	hsa-miR-4420	HITS-CLIP	19536157
MIRT713997	hsa-miR-653-3p	HITS-CLIP	19536157
MIRT713996	hsa-miR-3606-3p	HITS-CLIP	19536157
MIRT714004	hsa-miR-649	HITS-CLIP	19536157
MIRT714003	hsa-miR-6890-3p	HITS-CLIP	19536157
MIRT714002	hsa-miR-4742-3p	HITS-CLIP	19536157
MIRT714001	hsa-miR-5189-3p	HITS-CLIP	19536157
MIRT714000	hsa-miR-181b-2-3p	HITS-CLIP	19536157
MIRT713999	hsa-miR-181b-3p	HITS-CLIP	19536157
MIRT713998	hsa-miR-4420	HITS-CLIP	19536157
MIRT713997	hsa-miR-653-3p	HITS-CLIP	19536157
MIRT713996	hsa-miR-3606-3p	HITS-CLIP	19536157
MIRT714004	hsa-miR-649	HITS-CLIP	19536157
MIRT714003	hsa-miR-6890-3p	HITS-CLIP	19536157
MIRT714002	hsa-miR-4742-3p	HITS-CLIP	19536157
MIRT714001	hsa-miR-5189-3p	HITS-CLIP	19536157
MIRT714000	hsa-miR-181b-2-3p	HITS-CLIP	19536157
MIRT713999	hsa-miR-181b-3p	HITS-CLIP	19536157
MIRT713998	hsa-miR-4420	HITS-CLIP	19536157
MIRT713997	hsa-miR-653-3p	HITS-CLIP	19536157
MIRT713996	hsa-miR-3606-3p	HITS-CLIP	19536157
MIRT684677	hsa-miR-4438	HITS-CLIP	23313552
MIRT684676	hsa-miR-6504-3p	HITS-CLIP	23313552
MIRT684675	hsa-miR-3622a-3p	HITS-CLIP	23313552
MIRT684674	hsa-miR-3622b-3p	HITS-CLIP	23313552
MIRT684673	hsa-miR-6765-3p	HITS-CLIP	23313552
MIRT684672	hsa-miR-4691-3p	HITS-CLIP	23313552
MIRT684671	hsa-miR-4711-5p	HITS-CLIP	23313552
MIRT684670	hsa-miR-5095	HITS-CLIP	23313552
MIRT684669	hsa-miR-7151-3p	HITS-CLIP	23313552
MIRT684668	hsa-miR-3157-5p	HITS-CLIP	23313552
MIRT1358489	hsa-miR-106a	CLIP-seq
MIRT1358490	hsa-miR-106b	CLIP-seq
MIRT1358491	hsa-miR-1245	CLIP-seq
MIRT1358492	hsa-miR-1269	CLIP-seq
MIRT1358493	hsa-miR-1269b	CLIP-seq
MIRT1358494	hsa-miR-150	CLIP-seq
MIRT1358495	hsa-miR-17	CLIP-seq
MIRT1358496	hsa-miR-20a	CLIP-seq
MIRT1358497	hsa-miR-20b	CLIP-seq
MIRT1358498	hsa-miR-219-5p	CLIP-seq
MIRT1358499	hsa-miR-223	CLIP-seq
MIRT1358500	hsa-miR-299-3p	CLIP-seq
MIRT1358501	hsa-miR-302a	CLIP-seq
MIRT1358502	hsa-miR-302b	CLIP-seq
MIRT1358503	hsa-miR-302c	CLIP-seq
MIRT1358504	hsa-miR-302d	CLIP-seq
MIRT1358505	hsa-miR-302e	CLIP-seq
MIRT1358506	hsa-miR-3128	CLIP-seq
MIRT1358507	hsa-miR-3130-5p	CLIP-seq
MIRT1358508	hsa-miR-3136-3p	CLIP-seq
MIRT1358509	hsa-miR-3545-3p	CLIP-seq
MIRT1358510	hsa-miR-3622b-5p	CLIP-seq
MIRT1358511	hsa-miR-3650	CLIP-seq
MIRT1358512	hsa-miR-372	CLIP-seq
MIRT1358513	hsa-miR-373	CLIP-seq
MIRT1358514	hsa-miR-432	CLIP-seq
MIRT1358515	hsa-miR-4445	CLIP-seq
MIRT1358516	hsa-miR-4482	CLIP-seq
MIRT1358517	hsa-miR-4491	CLIP-seq
MIRT1358518	hsa-miR-4529-3p	CLIP-seq
MIRT1358519	hsa-miR-4652-3p	CLIP-seq
MIRT1358520	hsa-miR-4657	CLIP-seq
MIRT1358521	hsa-miR-4680-5p	CLIP-seq
MIRT1358522	hsa-miR-4697-3p	CLIP-seq
MIRT1358523	hsa-miR-4720-5p	CLIP-seq
MIRT1358524	hsa-miR-4724-3p	CLIP-seq
MIRT1358525	hsa-miR-4731-5p	CLIP-seq
MIRT1358526	hsa-miR-4757-5p	CLIP-seq
MIRT1358527	hsa-miR-4782-3p	CLIP-seq
MIRT1358528	hsa-miR-4799-3p	CLIP-seq
MIRT1358529	hsa-miR-508-3p	CLIP-seq
MIRT1358530	hsa-miR-512-3p	CLIP-seq
MIRT1358531	hsa-miR-519d	CLIP-seq
MIRT1358532	hsa-miR-520a-3p	CLIP-seq
MIRT1358533	hsa-miR-520b	CLIP-seq
MIRT1358534	hsa-miR-520c-3p	CLIP-seq
MIRT1358535	hsa-miR-520d-3p	CLIP-seq
MIRT1358536	hsa-miR-520e	CLIP-seq
MIRT1358537	hsa-miR-520g	CLIP-seq
MIRT1358538	hsa-miR-520h	CLIP-seq
MIRT1358539	hsa-miR-550b	CLIP-seq
MIRT1358540	hsa-miR-622	CLIP-seq
MIRT1358541	hsa-miR-663b	CLIP-seq
MIRT1358542	hsa-miR-93	CLIP-seq
MIRT1358543	hsa-miR-935	CLIP-seq
MIRT1358489	hsa-miR-106a	CLIP-seq
MIRT1358490	hsa-miR-106b	CLIP-seq
MIRT1358544	hsa-miR-1200	CLIP-seq
MIRT1358494	hsa-miR-150	CLIP-seq
MIRT1358495	hsa-miR-17	CLIP-seq
MIRT1358496	hsa-miR-20a	CLIP-seq
MIRT1358497	hsa-miR-20b	CLIP-seq
MIRT1358545	hsa-miR-21	CLIP-seq
MIRT1358498	hsa-miR-219-5p	CLIP-seq
MIRT1358501	hsa-miR-302a	CLIP-seq
MIRT1358502	hsa-miR-302b	CLIP-seq
MIRT1358503	hsa-miR-302c	CLIP-seq
MIRT1358504	hsa-miR-302d	CLIP-seq
MIRT1358505	hsa-miR-302e	CLIP-seq
MIRT1358546	hsa-miR-3160-3p	CLIP-seq
MIRT1358547	hsa-miR-3200-3p	CLIP-seq
MIRT1358548	hsa-miR-370	CLIP-seq
MIRT1358512	hsa-miR-372	CLIP-seq
MIRT1358513	hsa-miR-373	CLIP-seq
MIRT1358549	hsa-miR-4324	CLIP-seq
MIRT1358515	hsa-miR-4445	CLIP-seq
MIRT1358550	hsa-miR-4487	CLIP-seq
MIRT1358525	hsa-miR-4731-5p	CLIP-seq
MIRT1358527	hsa-miR-4782-3p	CLIP-seq
MIRT1358529	hsa-miR-508-3p	CLIP-seq
MIRT1358530	hsa-miR-512-3p	CLIP-seq
MIRT1358531	hsa-miR-519d	CLIP-seq
MIRT1358532	hsa-miR-520a-3p	CLIP-seq
MIRT1358533	hsa-miR-520b	CLIP-seq
MIRT1358534	hsa-miR-520c-3p	CLIP-seq
MIRT1358535	hsa-miR-520d-3p	CLIP-seq
MIRT1358536	hsa-miR-520e	CLIP-seq
MIRT1358537	hsa-miR-520g	CLIP-seq
MIRT1358538	hsa-miR-520h	CLIP-seq
MIRT1358551	hsa-miR-544b	CLIP-seq
MIRT1358552	hsa-miR-556-5p	CLIP-seq
MIRT1358553	hsa-miR-558	CLIP-seq
MIRT1358554	hsa-miR-582-5p	CLIP-seq
MIRT1358555	hsa-miR-590-5p	CLIP-seq
MIRT1358542	hsa-miR-93	CLIP-seq
MIRT1358545	hsa-miR-21	CLIP-seq
MIRT1358498	hsa-miR-219-5p	CLIP-seq
MIRT1358500	hsa-miR-299-3p	CLIP-seq
MIRT1358508	hsa-miR-3136-3p	CLIP-seq
MIRT1358511	hsa-miR-3650	CLIP-seq
MIRT2106211	hsa-miR-4278	CLIP-seq
MIRT1358515	hsa-miR-4445	CLIP-seq
MIRT1358517	hsa-miR-4491	CLIP-seq
MIRT1358520	hsa-miR-4657	CLIP-seq
MIRT2106212	hsa-miR-4716-3p	CLIP-seq
MIRT1358527	hsa-miR-4782-3p	CLIP-seq
MIRT1358529	hsa-miR-508-3p	CLIP-seq
MIRT1358539	hsa-miR-550b	CLIP-seq
MIRT1358555	hsa-miR-590-5p	CLIP-seq
MIRT1358541	hsa-miR-663b	CLIP-seq
MIRT1358489	hsa-miR-106a	CLIP-seq
MIRT1358490	hsa-miR-106b	CLIP-seq
MIRT2330507	hsa-miR-1224-5p	CLIP-seq
MIRT1358491	hsa-miR-1245	CLIP-seq
MIRT1358492	hsa-miR-1269	CLIP-seq
MIRT1358493	hsa-miR-1269b	CLIP-seq
MIRT2330508	hsa-miR-1286	CLIP-seq
MIRT1358494	hsa-miR-150	CLIP-seq
MIRT1358495	hsa-miR-17	CLIP-seq
MIRT1358496	hsa-miR-20a	CLIP-seq
MIRT1358497	hsa-miR-20b	CLIP-seq
MIRT1358501	hsa-miR-302a	CLIP-seq
MIRT1358502	hsa-miR-302b	CLIP-seq
MIRT1358503	hsa-miR-302c	CLIP-seq
MIRT1358504	hsa-miR-302d	CLIP-seq
MIRT1358505	hsa-miR-302e	CLIP-seq
MIRT1358512	hsa-miR-372	CLIP-seq
MIRT1358513	hsa-miR-373	CLIP-seq
MIRT2330509	hsa-miR-3918	CLIP-seq
MIRT1358514	hsa-miR-432	CLIP-seq
MIRT2330510	hsa-miR-4419a	CLIP-seq
MIRT2330511	hsa-miR-4459	CLIP-seq
MIRT2330512	hsa-miR-4510	CLIP-seq
MIRT1358518	hsa-miR-4529-3p	CLIP-seq
MIRT1358521	hsa-miR-4680-5p	CLIP-seq
MIRT2330513	hsa-miR-4685-5p	CLIP-seq
MIRT2330514	hsa-miR-4722-5p	CLIP-seq
MIRT1358525	hsa-miR-4731-5p	CLIP-seq
MIRT2330515	hsa-miR-4751	CLIP-seq
MIRT1358526	hsa-miR-4757-5p	CLIP-seq
MIRT2330516	hsa-miR-4779	CLIP-seq
MIRT1358530	hsa-miR-512-3p	CLIP-seq
MIRT1358531	hsa-miR-519d	CLIP-seq
MIRT1358532	hsa-miR-520a-3p	CLIP-seq
MIRT1358533	hsa-miR-520b	CLIP-seq
MIRT1358534	hsa-miR-520c-3p	CLIP-seq
MIRT1358535	hsa-miR-520d-3p	CLIP-seq
MIRT1358536	hsa-miR-520e	CLIP-seq
MIRT1358537	hsa-miR-520g	CLIP-seq
MIRT1358538	hsa-miR-520h	CLIP-seq
MIRT1358542	hsa-miR-93	CLIP-seq
MIRT2624544	hsa-miR-409-3p	CLIP-seq

Show/Hide all (19)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005353	Function	Fructose transmembrane transporter activity	IDA	17710649
GO:0005654	Component	Nucleoplasm	IDA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	12175779
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0008645	Process	Hexose transmembrane transport	TAS
GO:0015755	Process	Fructose transmembrane transport	IDA	17710649
GO:0016020	Component	Membrane	IEA
GO:0022857	Function	Transmembrane transporter activity	IEA
GO:0030054	Component	Cell junction	IDA
GO:0046323	Process	D-glucose import	IBA
GO:0051119	Function	Sugar transmembrane transporter activity	TAS
GO:0055056	Function	D-glucose transmembrane transporter activity	IBA
GO:0055056	Function	D-glucose transmembrane transporter activity	IDA	11583593, 12175779, 17710649
GO:0055056	Function	D-glucose transmembrane transporter activity	IEA
GO:0055085	Process	Transmembrane transport	IEA
GO:0070837	Process	Dehydroascorbic acid transport	IBA
GO:1904659	Process	D-glucose transmembrane transport	IDA	11583593, 12175779, 17710649

MIM	HGNC	e!Ensembl
610367	14239	ENSG00000133460

Q9BYW1

Protein name

Solute carrier family 2, facilitated glucose transporter member 11 (Glucose transporter type 11) (GLUT-11)

Protein function

Facilitative glucose transporter.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00083	Sugar_tr	15 → 471	Sugar (and other) transporter	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in heart and skeletal muscle. {ECO:0000269|PubMed:12175779}.

Sequence

MRALRRLIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPD
HLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGS
FEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRE
LLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLA
GELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVF
RKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALC
LQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLI
LVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFPRRA
QGPTWRSLEVIQSTEL

Sequence length

496

Interactions

View interactions

	Reactome
			Cellular hexose transport

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
HYPERTROPHIC CARDIOMYOPATHY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (12)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
ARTERIAL TORTUOSITY SYNDROME	Arterial Tortuosity Syndrome	BEFREE	16550171, 26376865, 27153185, 28829359, 29149261, 30800210, 31203799, 31621376		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	38019251	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiomyopathy Dilated	Dilated cardiomyopathy	Pubtator	27711126	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Connective Tissue Diseases	Connective Tissue Disease	BEFREE	27153185		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	11592815, 12941788, 15975113, 16336637, 16550171, 16586067, 17935213		★★★★★ ★☆☆☆☆ Found in Text Mining only
Loeys-Dietz Syndrome	Loeys-Dietz Syndrome	BEFREE	16550171		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	21938742		★★★★★ ★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Multiple myeloma	BEFREE	22452979		★★★★★ ★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Multiple myeloma	Pubtator	22452979	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	24736764		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pituitary Diseases	Pituitary Diseases	BEFREE	24736764		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	21938742		★★★★★ ★☆☆☆☆ Found in Text Mining only

SLC2A11 (solute carrier family 2 member 11)