LRRC61 (leucine rich repeat containing 61)

Gene

• Entrez ID: 65999
• Gene name: Leucine rich repeat containing 61
• Gene symbol: LRRC61
• Synonyms (NCBI Gene): HSPC295
• Chromosome: 7
• Chromosome location: 7q36.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT727263	hsa-miR-27a-3p	HITS-CLIP	22473208
MIRT727264	hsa-miR-27b-3p	HITS-CLIP	22473208
MIRT1120390	hsa-miR-139-3p	CLIP-seq
MIRT1120391	hsa-miR-3136-3p	CLIP-seq
MIRT1120392	hsa-miR-3137	CLIP-seq
MIRT1120393	hsa-miR-3162-3p	CLIP-seq
MIRT1120394	hsa-miR-3664-3p	CLIP-seq
MIRT1120395	hsa-miR-4433	CLIP-seq
MIRT1120396	hsa-miR-4459	CLIP-seq
MIRT1120397	hsa-miR-4768-3p	CLIP-seq
MIRT1120398	hsa-miR-483-5p	CLIP-seq
MIRT1120399	hsa-miR-485-5p	CLIP-seq
MIRT2034077	hsa-miR-103a	CLIP-seq
MIRT2034078	hsa-miR-107	CLIP-seq
MIRT2034079	hsa-miR-1193	CLIP-seq
MIRT2034080	hsa-miR-1266	CLIP-seq
MIRT2034081	hsa-miR-1301	CLIP-seq
MIRT2034082	hsa-miR-185	CLIP-seq
MIRT2034083	hsa-miR-3150a-3p	CLIP-seq
MIRT2034084	hsa-miR-3175	CLIP-seq
MIRT2034085	hsa-miR-3184	CLIP-seq
MIRT1120394	hsa-miR-3664-3p	CLIP-seq
MIRT2034086	hsa-miR-423-5p	CLIP-seq
MIRT2034087	hsa-miR-4306	CLIP-seq
MIRT2034088	hsa-miR-4491	CLIP-seq
MIRT2034089	hsa-miR-4518	CLIP-seq
MIRT2034090	hsa-miR-4644	CLIP-seq
MIRT2034091	hsa-miR-4657	CLIP-seq
MIRT2034092	hsa-miR-4728-5p	CLIP-seq
MIRT2034093	hsa-miR-491-5p	CLIP-seq
MIRT2034094	hsa-miR-502-5p	CLIP-seq
MIRT2034095	hsa-miR-5047	CLIP-seq
MIRT2034096	hsa-miR-516b	CLIP-seq
MIRT2034097	hsa-miR-541	CLIP-seq
MIRT2034098	hsa-miR-622	CLIP-seq
MIRT2034099	hsa-miR-654-5p	CLIP-seq
MIRT2034100	hsa-miR-939	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183, 32814053
GO:0005737	Component	Cytoplasm	IBA
GO:0036158	Process	Outer dynein arm assembly	IBA
GO:0043014	Function	Alpha-tubulin binding	IBA
GO:0045504	Function	Dynein heavy chain binding	IBA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q9BV99
• Protein name: Leucine-rich repeat-containing protein 61
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF13855	LRR_8	54 → 109	Leucine rich repeat	Repeat

• Sequence:

  MDPPAEKPGEAGGLQITPQLLKSRTGEFSLESILLLKLRGLGLADLGCLGECLGLEWLDL
  SGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLATCENLQSLNAAGNLLATPGQLQCLAG
  LPCLEYLRLRDPLARLSNPLCANPSYWAAVRELLPGLKVIDGERVIGRGSEFYQLCRDLD
  SSLRPSSSPGPRATEAQPWVEPGYWESWPSRSSSILEEACRQFQDTLQECWDLDRQASDS
  LAQAEQVLSSAGPTSSFVF

• Sequence length: 259

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
COLOR VISION DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations