ZFTA (zinc finger translocation associated)

Gene Gene information from NCBI Gene database.
Gene Gene ontology Other IDs Protein Associated diseases
Entrez ID 65998
Gene name Zinc finger translocation associated
Gene symbol ZFTA
Synonyms (NCBI Gene)
C11orf95
Chromosome 11
Chromosome location 11q13.1
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
2
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide all (2)
GO ID Ontology Definition Evidence Reference
GO:0005634 Component Nucleus IEA
GO:0045892 Process Negative regulation of DNA-templated transcription IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
615699 28449 ENSG00000188070
Protein Protein information from UniProt database.
Gene Gene ontology Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
C9JLR9
Protein name Zinc finger translocation-associated protein (ZFTA)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF18658 zf-C2H2_12 106 → 169 Spin-doc zinc-finger Domain
PF18658 zf-C2H2_12 265 → 328 Spin-doc zinc-finger Domain
PF18658 zf-C2H2_12 419 → 482 Spin-doc zinc-finger Domain
PF18658 zf-C2H2_12 582 → 645 Spin-doc zinc-finger Domain
Sequence 
MEPGGDHRSRSSGGRGGPGPAVASARGRRLPPAGSSGSAEPEEDEGGQDLQLEGGALGSW
GSAPLPSSRARGPASSGRKYSDHCEARASRPGKSRIPGRDHRRYYHDHWRLEYLMDFNPA
RHGMVCMVCGSSLATLKLSTIKRHIRQKHPYSLHWSPREKEVISNSWDAHLGLGACGEAE
GLGVQGAEEEEEEEEEEEEEGAGVPACPPKGPGKAPAGGGCRRQRRGGPVAPRARRLRLS
ASRRAGGSRGLGARRLERRLKESLQNWFRAECLMDYDPRGNRLVCMACGRALPSLHLDDI
RAHVLEVHPGSLGLSGPQRSALLQAWGGQPEALSELTQSPPGDDLAPQDLTGKSRDSASA
AGAPSSQDLSPPDVKEEAGWVPERPGPAEEEEELEEGEGERAGVPGRSPRGRAHRRHPQE
RWRLEYLMELDGGRRGLVCGVCGGALASLKMSTIERHIRRRHPGSTRLGGPVQALIAREW
SEKAAHLLALGPPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLE
RPAEEEEDEEDGQEPGGLALPPPPPPPPPPPPRSREQRRNYQPRWRGEYLMDYDGSRRGL
VCMVCGGALATLKVSTIKRHILQVHPFSMDFTPEERQTILEAYEEAALRCYGHEGFGPPA
PAPRDGGADLKSGAVCRA
Sequence length 678
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
Gene Gene ontology Other IDs Protein Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (2)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ALZHEIMER DISEASE — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Show/Hide Text Mining Associations (16)
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Ependymoma Ependymoma BEFREE 24553141, 25182241, 25388523, 27022130, 27121356, 29354850, 29949764, 30325077, 30514397, 30631904, 31150846, 31375768
★★★★★
★☆☆☆☆
Found in Text Mining only
Ependymoma Ependymoma ORPHANET_DG 24553141
★★★★★
★☆☆☆☆
Found in Text Mining only
Ependymoma Ependymoma Orphanet
★★★★★
★☆☆☆☆
Found in Text Mining only
Ependymoma Ependymoma HPO_DG
★★★★★
★☆☆☆☆
Found in Text Mining only
Liver neoplasms Liver neoplasms HPO_DG
★★★★★
★☆☆☆☆
Found in Text Mining only
Lung Neoplasms Lung Neoplasms HPO_DG
★★★★★
★☆☆☆☆
Found in Text Mining only
Mammary Neoplasms Mammary Neoplasms HPO_DG
★★★★★
★☆☆☆☆
Found in Text Mining only
Migraine Disorders Migraine HPO_DG
★★★★★
★☆☆☆☆
Found in Text Mining only
Neoplasms Neoplasms BEFREE 24553141, 25388523, 30514397
★★★★★
★☆☆☆☆
Found in Text Mining only
ovarian neoplasm Ovarian neoplasm HPO_DG
★★★★★
★☆☆☆☆
Found in Text Mining only