MPPE1 (metallophosphoesterase 1)

Gene

• Entrez ID: 65258
• Gene name: Metallophosphoesterase 1
• Gene symbol: MPPE1
• Synonyms (NCBI Gene): Cdc1, PGAP5
• Chromosome: 18
• Chromosome location: 18p11.21

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT027280	hsa-miR-101-3p	Sequencing	20371350
MIRT708307	hsa-miR-6753-5p	HITS-CLIP	19536157
MIRT708306	hsa-miR-6750-5p	HITS-CLIP	19536157
MIRT708305	hsa-miR-6822-5p	HITS-CLIP	19536157
MIRT708304	hsa-miR-7113-5p	HITS-CLIP	19536157
MIRT708303	hsa-miR-7110-3p	HITS-CLIP	19536157
MIRT708302	hsa-miR-6817-3p	HITS-CLIP	19536157
MIRT708301	hsa-miR-1290	HITS-CLIP	19536157
MIRT708300	hsa-miR-6873-3p	HITS-CLIP	19536157
MIRT708299	hsa-miR-4768-5p	HITS-CLIP	19536157
MIRT708298	hsa-miR-6833-3p	HITS-CLIP	19536157
MIRT708297	hsa-miR-6809-3p	HITS-CLIP	19536157
MIRT661206	hsa-miR-216b-5p	HITS-CLIP	23824327
MIRT661205	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT661204	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT661203	hsa-miR-940	HITS-CLIP	23824327
MIRT661202	hsa-miR-3929	HITS-CLIP	23824327
MIRT661201	hsa-miR-4419b	HITS-CLIP	23824327
MIRT661199	hsa-miR-4478	HITS-CLIP	23824327
MIRT661200	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT661198	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT661197	hsa-miR-4635	HITS-CLIP	23824327
MIRT661196	hsa-miR-1827	HITS-CLIP	23824327
MIRT661195	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT661194	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT661193	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT661192	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT617108	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT617107	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT617106	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT617105	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT617104	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT617103	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT617102	hsa-miR-1976	HITS-CLIP	23824327
MIRT617101	hsa-miR-4774-5p	HITS-CLIP	23824327
MIRT617100	hsa-miR-133a-5p	HITS-CLIP	23824327
MIRT642362	hsa-miR-4320	HITS-CLIP	23824327
MIRT617099	hsa-miR-5681b	HITS-CLIP	23824327
MIRT642361	hsa-miR-4279	HITS-CLIP	23824327
MIRT617108	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT617107	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT617106	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT617105	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT617104	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT617103	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT617102	hsa-miR-1976	HITS-CLIP	23824327
MIRT617101	hsa-miR-4774-5p	HITS-CLIP	23824327
MIRT617100	hsa-miR-133a-5p	HITS-CLIP	23824327
MIRT617099	hsa-miR-5681b	HITS-CLIP	23824327
MIRT708307	hsa-miR-6753-5p	HITS-CLIP	19536157
MIRT708306	hsa-miR-6750-5p	HITS-CLIP	19536157
MIRT708305	hsa-miR-6822-5p	HITS-CLIP	19536157
MIRT708304	hsa-miR-7113-5p	HITS-CLIP	19536157
MIRT708303	hsa-miR-7110-3p	HITS-CLIP	19536157
MIRT708302	hsa-miR-6817-3p	HITS-CLIP	19536157
MIRT708301	hsa-miR-1290	HITS-CLIP	19536157
MIRT708300	hsa-miR-6873-3p	HITS-CLIP	19536157
MIRT708299	hsa-miR-4768-5p	HITS-CLIP	19536157
MIRT708298	hsa-miR-6833-3p	HITS-CLIP	19536157
MIRT708297	hsa-miR-6809-3p	HITS-CLIP	19536157
MIRT661206	hsa-miR-216b-5p	HITS-CLIP	23824327
MIRT661205	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT661204	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT661203	hsa-miR-940	HITS-CLIP	23824327
MIRT661202	hsa-miR-3929	HITS-CLIP	23824327
MIRT661201	hsa-miR-4419b	HITS-CLIP	23824327
MIRT661199	hsa-miR-4478	HITS-CLIP	23824327
MIRT661200	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT661198	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT661197	hsa-miR-4635	HITS-CLIP	23824327
MIRT661196	hsa-miR-1827	HITS-CLIP	23824327
MIRT661195	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT661194	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT661193	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT661192	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT617108	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT617107	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT617106	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT617105	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT617104	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT617103	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT617102	hsa-miR-1976	HITS-CLIP	23824327
MIRT617101	hsa-miR-4774-5p	HITS-CLIP	23824327
MIRT617100	hsa-miR-133a-5p	HITS-CLIP	23824327
MIRT642362	hsa-miR-4320	HITS-CLIP	23824327
MIRT617099	hsa-miR-5681b	HITS-CLIP	23824327
MIRT642361	hsa-miR-4279	HITS-CLIP	23824327
MIRT617108	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT617107	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT617106	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT617105	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT617104	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT617103	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT617102	hsa-miR-1976	HITS-CLIP	23824327
MIRT617101	hsa-miR-4774-5p	HITS-CLIP	23824327
MIRT617100	hsa-miR-133a-5p	HITS-CLIP	23824327
MIRT617099	hsa-miR-5681b	HITS-CLIP	23824327
MIRT1156570	hsa-miR-106a	CLIP-seq
MIRT1156571	hsa-miR-106b	CLIP-seq
MIRT1156572	hsa-miR-122	CLIP-seq
MIRT1156573	hsa-miR-1245	CLIP-seq
MIRT1156574	hsa-miR-1281	CLIP-seq
MIRT1156575	hsa-miR-150	CLIP-seq
MIRT1156576	hsa-miR-17	CLIP-seq
MIRT1156577	hsa-miR-20a	CLIP-seq
MIRT1156578	hsa-miR-20b	CLIP-seq
MIRT1156579	hsa-miR-24	CLIP-seq
MIRT1156580	hsa-miR-302a	CLIP-seq
MIRT1156581	hsa-miR-302b	CLIP-seq
MIRT1156582	hsa-miR-302c	CLIP-seq
MIRT1156583	hsa-miR-302d	CLIP-seq
MIRT1156584	hsa-miR-3135b	CLIP-seq
MIRT1156585	hsa-miR-3545-3p	CLIP-seq
MIRT1156586	hsa-miR-3622b-5p	CLIP-seq
MIRT1156587	hsa-miR-3652	CLIP-seq
MIRT1156588	hsa-miR-3663-5p	CLIP-seq
MIRT1156589	hsa-miR-372	CLIP-seq
MIRT1156590	hsa-miR-373	CLIP-seq
MIRT1156591	hsa-miR-4284	CLIP-seq
MIRT1156592	hsa-miR-4423-5p	CLIP-seq
MIRT1156593	hsa-miR-4430	CLIP-seq
MIRT1156594	hsa-miR-4532	CLIP-seq
MIRT1156595	hsa-miR-4680-5p	CLIP-seq
MIRT1156596	hsa-miR-4772-3p	CLIP-seq
MIRT1156597	hsa-miR-519d	CLIP-seq
MIRT1156598	hsa-miR-520g	CLIP-seq
MIRT1156599	hsa-miR-93	CLIP-seq
MIRT1156600	hsa-miR-1179	CLIP-seq
MIRT1156601	hsa-miR-1183	CLIP-seq
MIRT1156573	hsa-miR-1245	CLIP-seq
MIRT1156602	hsa-miR-1267	CLIP-seq
MIRT1156603	hsa-miR-129-5p	CLIP-seq
MIRT1156604	hsa-miR-139-3p	CLIP-seq
MIRT1156605	hsa-miR-1913	CLIP-seq
MIRT1156606	hsa-miR-197	CLIP-seq
MIRT1156607	hsa-miR-3187-3p	CLIP-seq
MIRT1156608	hsa-miR-324-3p	CLIP-seq
MIRT1156585	hsa-miR-3545-3p	CLIP-seq
MIRT1156588	hsa-miR-3663-5p	CLIP-seq
MIRT1156609	hsa-miR-3664-5p	CLIP-seq
MIRT1156610	hsa-miR-3672	CLIP-seq
MIRT1156611	hsa-miR-3682-3p	CLIP-seq
MIRT1156612	hsa-miR-4294	CLIP-seq
MIRT1156592	hsa-miR-4423-5p	CLIP-seq
MIRT1156613	hsa-miR-4435	CLIP-seq
MIRT1156614	hsa-miR-4639-3p	CLIP-seq
MIRT1156595	hsa-miR-4680-5p	CLIP-seq
MIRT1156615	hsa-miR-4695-3p	CLIP-seq
MIRT1156616	hsa-miR-4701-5p	CLIP-seq
MIRT1156617	hsa-miR-4716-5p	CLIP-seq
MIRT1156618	hsa-miR-4755-3p	CLIP-seq
MIRT1156619	hsa-miR-4781-3p	CLIP-seq
MIRT1156620	hsa-miR-5096	CLIP-seq
MIRT1156621	hsa-miR-548s	CLIP-seq
MIRT1156622	hsa-miR-588	CLIP-seq
MIRT1156623	hsa-miR-633	CLIP-seq
MIRT2044842	hsa-miR-101	CLIP-seq
MIRT1156572	hsa-miR-122	CLIP-seq
MIRT1156602	hsa-miR-1267	CLIP-seq
MIRT1156603	hsa-miR-129-5p	CLIP-seq
MIRT1156604	hsa-miR-139-3p	CLIP-seq
MIRT2044843	hsa-miR-146a	CLIP-seq
MIRT2044844	hsa-miR-146b-5p	CLIP-seq
MIRT1156579	hsa-miR-24	CLIP-seq
MIRT1156584	hsa-miR-3135b	CLIP-seq
MIRT1156586	hsa-miR-3622b-5p	CLIP-seq
MIRT1156587	hsa-miR-3652	CLIP-seq
MIRT1156609	hsa-miR-3664-5p	CLIP-seq
MIRT1156610	hsa-miR-3672	CLIP-seq
MIRT2044845	hsa-miR-4276	CLIP-seq
MIRT1156591	hsa-miR-4284	CLIP-seq
MIRT1156612	hsa-miR-4294	CLIP-seq
MIRT1156592	hsa-miR-4423-5p	CLIP-seq
MIRT1156593	hsa-miR-4430	CLIP-seq
MIRT1156614	hsa-miR-4639-3p	CLIP-seq
MIRT2044846	hsa-miR-4773	CLIP-seq
MIRT2044847	hsa-miR-589	CLIP-seq
MIRT2044842	hsa-miR-101	CLIP-seq
MIRT1156570	hsa-miR-106a	CLIP-seq
MIRT1156571	hsa-miR-106b	CLIP-seq
MIRT1156572	hsa-miR-122	CLIP-seq
MIRT1156573	hsa-miR-1245	CLIP-seq
MIRT1156602	hsa-miR-1267	CLIP-seq
MIRT2274054	hsa-miR-1275	CLIP-seq
MIRT1156603	hsa-miR-129-5p	CLIP-seq
MIRT2274055	hsa-miR-1343	CLIP-seq
MIRT1156604	hsa-miR-139-3p	CLIP-seq
MIRT2274056	hsa-miR-144	CLIP-seq
MIRT1156575	hsa-miR-150	CLIP-seq
MIRT1156576	hsa-miR-17	CLIP-seq
MIRT1156577	hsa-miR-20a	CLIP-seq
MIRT1156578	hsa-miR-20b	CLIP-seq
MIRT1156579	hsa-miR-24	CLIP-seq
MIRT1156580	hsa-miR-302a	CLIP-seq
MIRT1156581	hsa-miR-302b	CLIP-seq
MIRT1156582	hsa-miR-302c	CLIP-seq
MIRT1156583	hsa-miR-302d	CLIP-seq
MIRT1156584	hsa-miR-3135b	CLIP-seq
MIRT2274057	hsa-miR-3169	CLIP-seq
MIRT2274058	hsa-miR-3607-5p	CLIP-seq
MIRT1156586	hsa-miR-3622b-5p	CLIP-seq
MIRT1156587	hsa-miR-3652	CLIP-seq
MIRT1156609	hsa-miR-3664-5p	CLIP-seq
MIRT2274059	hsa-miR-3667-3p	CLIP-seq
MIRT1156610	hsa-miR-3672	CLIP-seq
MIRT1156589	hsa-miR-372	CLIP-seq
MIRT1156590	hsa-miR-373	CLIP-seq
MIRT2274060	hsa-miR-376c	CLIP-seq
MIRT1156591	hsa-miR-4284	CLIP-seq
MIRT1156612	hsa-miR-4294	CLIP-seq
MIRT1156592	hsa-miR-4423-5p	CLIP-seq
MIRT1156593	hsa-miR-4430	CLIP-seq
MIRT2274061	hsa-miR-4440	CLIP-seq
MIRT2274062	hsa-miR-4525	CLIP-seq
MIRT1156614	hsa-miR-4639-3p	CLIP-seq
MIRT2274063	hsa-miR-4665-5p	CLIP-seq
MIRT2274064	hsa-miR-4723-5p	CLIP-seq
MIRT2274065	hsa-miR-4733-3p	CLIP-seq
MIRT1156596	hsa-miR-4772-3p	CLIP-seq
MIRT2274066	hsa-miR-517a	CLIP-seq
MIRT2274067	hsa-miR-517b	CLIP-seq
MIRT2274068	hsa-miR-517c	CLIP-seq
MIRT1156597	hsa-miR-519d	CLIP-seq
MIRT1156598	hsa-miR-520g	CLIP-seq
MIRT2274069	hsa-miR-552	CLIP-seq
MIRT2274070	hsa-miR-582-5p	CLIP-seq
MIRT2274071	hsa-miR-625	CLIP-seq
MIRT2274072	hsa-miR-637	CLIP-seq
MIRT1156599	hsa-miR-93	CLIP-seq
MIRT1156572	hsa-miR-122	CLIP-seq
MIRT1156602	hsa-miR-1267	CLIP-seq
MIRT1156584	hsa-miR-3135b	CLIP-seq
MIRT1156586	hsa-miR-3622b-5p	CLIP-seq
MIRT1156587	hsa-miR-3652	CLIP-seq
MIRT1156609	hsa-miR-3664-5p	CLIP-seq
MIRT1156592	hsa-miR-4423-5p	CLIP-seq
MIRT1156593	hsa-miR-4430	CLIP-seq
MIRT1156614	hsa-miR-4639-3p	CLIP-seq
MIRT2044842	hsa-miR-101	CLIP-seq
MIRT1156572	hsa-miR-122	CLIP-seq
MIRT2572871	hsa-miR-1234	CLIP-seq
MIRT1156602	hsa-miR-1267	CLIP-seq
MIRT1156574	hsa-miR-1281	CLIP-seq
MIRT1156604	hsa-miR-139-3p	CLIP-seq
MIRT2044843	hsa-miR-146a	CLIP-seq
MIRT2044844	hsa-miR-146b-5p	CLIP-seq
MIRT2572872	hsa-miR-1587	CLIP-seq
MIRT2572873	hsa-miR-1911	CLIP-seq
MIRT1156605	hsa-miR-1913	CLIP-seq
MIRT1156579	hsa-miR-24	CLIP-seq
MIRT2572874	hsa-miR-2467-3p	CLIP-seq
MIRT1156584	hsa-miR-3135b	CLIP-seq
MIRT2572875	hsa-miR-3145-3p	CLIP-seq
MIRT2572876	hsa-miR-3149	CLIP-seq
MIRT2572877	hsa-miR-3161	CLIP-seq
MIRT1156608	hsa-miR-324-3p	CLIP-seq
MIRT2572878	hsa-miR-3613-5p	CLIP-seq
MIRT1156586	hsa-miR-3622b-5p	CLIP-seq
MIRT1156587	hsa-miR-3652	CLIP-seq
MIRT2572879	hsa-miR-3662	CLIP-seq
MIRT1156609	hsa-miR-3664-5p	CLIP-seq
MIRT2572880	hsa-miR-3674	CLIP-seq
MIRT2572881	hsa-miR-3678-3p	CLIP-seq
MIRT2572882	hsa-miR-374a	CLIP-seq
MIRT2572883	hsa-miR-374b	CLIP-seq
MIRT2572884	hsa-miR-3944-5p	CLIP-seq
MIRT1156591	hsa-miR-4284	CLIP-seq
MIRT1156612	hsa-miR-4294	CLIP-seq
MIRT1156592	hsa-miR-4423-5p	CLIP-seq
MIRT1156593	hsa-miR-4430	CLIP-seq
MIRT2572885	hsa-miR-4436b-5p	CLIP-seq
MIRT2572886	hsa-miR-4437	CLIP-seq
MIRT1156594	hsa-miR-4532	CLIP-seq
MIRT1156614	hsa-miR-4639-3p	CLIP-seq
MIRT2572887	hsa-miR-4652-3p	CLIP-seq
MIRT2572888	hsa-miR-4674	CLIP-seq
MIRT1156615	hsa-miR-4695-3p	CLIP-seq
MIRT2572889	hsa-miR-4732-5p	CLIP-seq
MIRT2572890	hsa-miR-4735-5p	CLIP-seq
MIRT1156596	hsa-miR-4772-3p	CLIP-seq
MIRT2044846	hsa-miR-4773	CLIP-seq
MIRT2572891	hsa-miR-4775	CLIP-seq
MIRT2572892	hsa-miR-539	CLIP-seq
MIRT2572893	hsa-miR-548c-3p	CLIP-seq
MIRT2572894	hsa-miR-570	CLIP-seq
MIRT2572895	hsa-miR-578	CLIP-seq
MIRT2572896	hsa-miR-580	CLIP-seq
MIRT2044847	hsa-miR-589	CLIP-seq
MIRT2572897	hsa-miR-590-3p	CLIP-seq
MIRT2572898	hsa-miR-635	CLIP-seq
MIRT1156572	hsa-miR-122	CLIP-seq
MIRT2572871	hsa-miR-1234	CLIP-seq
MIRT1156602	hsa-miR-1267	CLIP-seq
MIRT1156574	hsa-miR-1281	CLIP-seq
MIRT1156604	hsa-miR-139-3p	CLIP-seq
MIRT2572872	hsa-miR-1587	CLIP-seq
MIRT1156605	hsa-miR-1913	CLIP-seq
MIRT1156579	hsa-miR-24	CLIP-seq
MIRT2572874	hsa-miR-2467-3p	CLIP-seq
MIRT1156584	hsa-miR-3135b	CLIP-seq
MIRT2572875	hsa-miR-3145-3p	CLIP-seq
MIRT2572876	hsa-miR-3149	CLIP-seq
MIRT1156608	hsa-miR-324-3p	CLIP-seq
MIRT1156586	hsa-miR-3622b-5p	CLIP-seq
MIRT1156587	hsa-miR-3652	CLIP-seq
MIRT1156609	hsa-miR-3664-5p	CLIP-seq
MIRT2572881	hsa-miR-3678-3p	CLIP-seq
MIRT2572884	hsa-miR-3944-5p	CLIP-seq
MIRT1156591	hsa-miR-4284	CLIP-seq
MIRT1156612	hsa-miR-4294	CLIP-seq
MIRT1156592	hsa-miR-4423-5p	CLIP-seq
MIRT1156593	hsa-miR-4430	CLIP-seq
MIRT2572885	hsa-miR-4436b-5p	CLIP-seq
MIRT2572886	hsa-miR-4437	CLIP-seq
MIRT1156594	hsa-miR-4532	CLIP-seq
MIRT1156614	hsa-miR-4639-3p	CLIP-seq
MIRT2572887	hsa-miR-4652-3p	CLIP-seq
MIRT2572888	hsa-miR-4674	CLIP-seq
MIRT1156615	hsa-miR-4695-3p	CLIP-seq
MIRT2572890	hsa-miR-4735-5p	CLIP-seq
MIRT1156596	hsa-miR-4772-3p	CLIP-seq
MIRT2572891	hsa-miR-4775	CLIP-seq
MIRT2572895	hsa-miR-578	CLIP-seq
MIRT2572896	hsa-miR-580	CLIP-seq
MIRT2572897	hsa-miR-590-3p	CLIP-seq
MIRT2572898	hsa-miR-635	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956
GO:0005654	Component	Nucleoplasm	IDA
GO:0005793	Component	Endoplasmic reticulum-Golgi intermediate compartment	IEA
GO:0005794	Component	Golgi apparatus	IDA
GO:0005794	Component	Golgi apparatus	IEA
GO:0006506	Process	GPI anchor biosynthetic process	IEA
GO:0006506	Process	GPI anchor biosynthetic process	IMP	29374258
GO:0006506	Process	GPI anchor biosynthetic process	ISS
GO:0006888	Process	Endoplasmic reticulum to Golgi vesicle-mediated transport	IEA
GO:0006888	Process	Endoplasmic reticulum to Golgi vesicle-mediated transport	ISS
GO:0008081	Function	Phosphoric diester hydrolase activity	IEA
GO:0016020	Component	Membrane	IEA
GO:0016192	Process	Vesicle-mediated transport	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0030145	Function	Manganese ion binding	ISS
GO:0033116	Component	Endoplasmic reticulum-Golgi intermediate compartment membrane	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0062050	Function	GPI-mannose ethanolamine phosphate phosphodiesterase activity	ISS
GO:0070971	Component	Endoplasmic reticulum exit site	ISS

Other IDs

• MIM: 611900
• HGNC: 15988
• e!Ensembl: ENSG00000154889

Protein

• UniProt ID: Q53F39
• Protein name: Metallophosphoesterase 1 (EC 3.1.-.-) (Post-GPI attachment to proteins factor 5)
• Protein function: Metallophosphoesterase that catalyzes the removal of a side-chain ethanolamine-phosphate (EtNP) from the second mannose of the GPI-anchor protein intermediate (PubMed:19837036, PubMed:29374258). Participates in the glycan remodeling steps of GPI
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00149	Metallophos	70 → 307	Calcineurin-like phosphoesterase	Domain

• Tissue specificity: TISSUE SPECIFICITY: Expressed in brain. {ECO:0000269|PubMed:11978971}.
• Sequence:

  MAMIELGFGRQNFHPLKRKSSLLLKLIAVVFAVLLFCEFLIYYLAIFQCNWPEVKTTASD
  GEQTTREPVLKAMFLADTHLLGEFLGHWLDKLRREWQMERAFQTALWLLQPEVVFILGDI
  FDEGKWSTPEAWADDVERFQKMFRHPSHVQLKVVAGNHDIGFHYEMNTYKVERFEKVFSS
  ERLFSWKGINFVMVNSVALNGDGCGICSETEAELIEVSHRLNCSREARGSSRCGPGPLLP
  TSAPVLLQHYPLYRRSDANCSGEDAAPAEERDIPFKENYDVLSREASQKLLWWLQPRLVL
  SGHTHSACEVHHGGRVPELSVPSFSWRNRNNPSFIMGSITPTDYTLSKCYLPREDVVLII
  YCGVVGFLVVLTLTHFGLLASPFLSGLNLLGKRKTR

• Sequence length: 396

Pathways

KEGG:

Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
Metabolic pathways

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
BIPOLAR DISORDER	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
IGA GLOMERULONEPHRITIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OCULAR HYPOTENSION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Bipolar Disorder	Bipolar Disorder	BEFREE	19859903		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Bipolar Disorder	Bipolar Disorder	PSYGENET_DG	19859903		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Bipolar Disorder	Bipolar disorder	Pubtator	19859903	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Borderline Personality Disorder	Borderline personality disorder	BEFREE	19859903		★☆☆☆☆ Found in Text Mining only
Bronchopulmonary Dysplasia	Bronchopulmonary Dysplasia	BEFREE	19859903		★☆☆☆☆ Found in Text Mining only
Collecting Duct Carcinoma of the Kidney	Renal Carcinoma	BEFREE	27144525		★☆☆☆☆ Found in Text Mining only
Dyssomnias	Dyssomnia	BEFREE	19508289		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	28125570, 29429633, 29920767, 30809220, 30961656, 31143179, 31810552		★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	BEFREE	29920767		★☆☆☆☆ Found in Text Mining only
MYELODYSPLASTIC SYNDROME	Myelodysplastic Syndrome	BEFREE	31244860		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	29429633, 29549977, 29628306, 29920767, 30352680, 30949170, 30961656, 31227597		★☆☆☆☆ Found in Text Mining only
Sleep Disorders	Sleep Disorders	BEFREE	19508289		★☆☆☆☆ Found in Text Mining only