Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	65082
Gene name	VPS33A core subunit of CORVET and HOPS complexes
Gene symbol	VPS33A
Synonyms (NCBI Gene)	MPSPS
Chromosome	12
Chromosome location	12q24.31
Summary	This gene encodes a tethering protein and a core subunit of the homotypic fusion and protein sorting (HOPS) complex. The HOPS complex and a second endosomal tethering complex called the class C core vacuole/endosome tethering (CORVET) complex, perform div

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SNP ID	Visualize variation	Clinical significance	Consequence
rs767748011	G>A	Pathogenic	Coding sequence variant, missense variant, genic downstream transcript variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT027508	hsa-miR-98-5p	Microarray	19088304
MIRT029192	hsa-miR-26b-5p	Microarray	19088304
MIRT552930	hsa-miR-30e-5p	PAR-CLIP	21572407
MIRT552929	hsa-miR-30d-5p	PAR-CLIP	21572407
MIRT552928	hsa-miR-30a-5p	PAR-CLIP	21572407
MIRT552927	hsa-miR-30c-5p	PAR-CLIP	21572407
MIRT552926	hsa-miR-30b-5p	PAR-CLIP	21572407
MIRT552925	hsa-miR-32-3p	PAR-CLIP	21572407
MIRT552924	hsa-miR-545-5p	PAR-CLIP	21572407
MIRT552923	hsa-miR-199a-3p	PAR-CLIP	21572407
MIRT552922	hsa-miR-199b-3p	PAR-CLIP	21572407
MIRT552921	hsa-miR-3129-5p	PAR-CLIP	21572407
MIRT552920	hsa-miR-3653-3p	PAR-CLIP	21572407
MIRT460809	hsa-miR-302f	PAR-CLIP	23592263
MIRT460808	hsa-miR-4695-5p	PAR-CLIP	23592263
MIRT460807	hsa-miR-4779	PAR-CLIP	23592263
MIRT460806	hsa-miR-6808-5p	PAR-CLIP	23592263
MIRT460805	hsa-miR-6893-5p	PAR-CLIP	23592263
MIRT460804	hsa-miR-940	PAR-CLIP	23592263
MIRT460803	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT460802	hsa-miR-219b-3p	PAR-CLIP	23592263
MIRT460801	hsa-miR-1827	PAR-CLIP	23592263
MIRT460800	hsa-miR-6134	PAR-CLIP	23592263
MIRT460799	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT460798	hsa-miR-3689d	PAR-CLIP	23592263
MIRT460797	hsa-miR-6851-5p	PAR-CLIP	23592263
MIRT460796	hsa-miR-6880-5p	PAR-CLIP	23592263
MIRT460795	hsa-miR-7847-3p	PAR-CLIP	23592263
MIRT460794	hsa-miR-4266	PAR-CLIP	23592263
MIRT460793	hsa-miR-1273e	PAR-CLIP	23592263
MIRT552930	hsa-miR-30e-5p	PAR-CLIP	21572407
MIRT552929	hsa-miR-30d-5p	PAR-CLIP	21572407
MIRT552928	hsa-miR-30a-5p	PAR-CLIP	21572407
MIRT552927	hsa-miR-30c-5p	PAR-CLIP	21572407
MIRT552926	hsa-miR-30b-5p	PAR-CLIP	21572407
MIRT552925	hsa-miR-32-3p	PAR-CLIP	21572407
MIRT552924	hsa-miR-545-5p	PAR-CLIP	21572407
MIRT552923	hsa-miR-199a-3p	PAR-CLIP	21572407
MIRT552922	hsa-miR-199b-3p	PAR-CLIP	21572407
MIRT552921	hsa-miR-3129-5p	PAR-CLIP	21572407
MIRT552920	hsa-miR-3653-3p	PAR-CLIP	21572407
MIRT460809	hsa-miR-302f	PAR-CLIP	23592263
MIRT460808	hsa-miR-4695-5p	PAR-CLIP	23592263
MIRT460807	hsa-miR-4779	PAR-CLIP	23592263
MIRT460806	hsa-miR-6808-5p	PAR-CLIP	23592263
MIRT460805	hsa-miR-6893-5p	PAR-CLIP	23592263
MIRT460804	hsa-miR-940	PAR-CLIP	23592263
MIRT460803	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT460802	hsa-miR-219b-3p	PAR-CLIP	23592263
MIRT460801	hsa-miR-1827	PAR-CLIP	23592263
MIRT460800	hsa-miR-6134	PAR-CLIP	23592263
MIRT460799	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT460798	hsa-miR-3689d	PAR-CLIP	23592263
MIRT460797	hsa-miR-6851-5p	PAR-CLIP	23592263
MIRT460796	hsa-miR-6880-5p	PAR-CLIP	23592263
MIRT460795	hsa-miR-7847-3p	PAR-CLIP	23592263
MIRT460794	hsa-miR-4266	PAR-CLIP	23592263
MIRT460793	hsa-miR-1273e	PAR-CLIP	23592263
MIRT1486461	hsa-let-7a	CLIP-seq
MIRT1486462	hsa-let-7b	CLIP-seq
MIRT1486463	hsa-let-7c	CLIP-seq
MIRT1486464	hsa-let-7d	CLIP-seq
MIRT1486465	hsa-let-7e	CLIP-seq
MIRT1486466	hsa-let-7f	CLIP-seq
MIRT1486467	hsa-let-7g	CLIP-seq
MIRT1486468	hsa-let-7i	CLIP-seq
MIRT1486469	hsa-miR-1184	CLIP-seq
MIRT1486470	hsa-miR-1205	CLIP-seq
MIRT1486471	hsa-miR-1227	CLIP-seq
MIRT1486472	hsa-miR-1264	CLIP-seq
MIRT1486473	hsa-miR-196a	CLIP-seq
MIRT1486474	hsa-miR-196b	CLIP-seq
MIRT1486475	hsa-miR-2053	CLIP-seq
MIRT1486476	hsa-miR-2114	CLIP-seq
MIRT1486477	hsa-miR-2964a-3p	CLIP-seq
MIRT1486478	hsa-miR-30a	CLIP-seq
MIRT1486479	hsa-miR-30b	CLIP-seq
MIRT1486480	hsa-miR-30c	CLIP-seq
MIRT1486481	hsa-miR-30d	CLIP-seq
MIRT1486482	hsa-miR-30e	CLIP-seq
MIRT1486483	hsa-miR-3158-5p	CLIP-seq
MIRT1486484	hsa-miR-3170	CLIP-seq
MIRT1486485	hsa-miR-323-5p	CLIP-seq
MIRT1486486	hsa-miR-3591-3p	CLIP-seq
MIRT1486487	hsa-miR-3664-3p	CLIP-seq
MIRT1486488	hsa-miR-3675-5p	CLIP-seq
MIRT1486489	hsa-miR-3682-5p	CLIP-seq
MIRT1486490	hsa-miR-3929	CLIP-seq
MIRT1486491	hsa-miR-4252	CLIP-seq
MIRT1486492	hsa-miR-4279	CLIP-seq
MIRT1486493	hsa-miR-4291	CLIP-seq
MIRT1486494	hsa-miR-4419b	CLIP-seq
MIRT1486495	hsa-miR-4433	CLIP-seq
MIRT1486496	hsa-miR-4455	CLIP-seq
MIRT1486497	hsa-miR-4458	CLIP-seq
MIRT1486498	hsa-miR-4459	CLIP-seq
MIRT1486499	hsa-miR-4478	CLIP-seq
MIRT1486500	hsa-miR-4500	CLIP-seq
MIRT1486501	hsa-miR-4539	CLIP-seq
MIRT1486502	hsa-miR-4649-3p	CLIP-seq
MIRT1486503	hsa-miR-4659a-3p	CLIP-seq
MIRT1486504	hsa-miR-4659b-3p	CLIP-seq
MIRT1486505	hsa-miR-4778-5p	CLIP-seq
MIRT1486506	hsa-miR-4786-5p	CLIP-seq
MIRT1486507	hsa-miR-4793-3p	CLIP-seq
MIRT1486508	hsa-miR-485-5p	CLIP-seq
MIRT1486509	hsa-miR-494	CLIP-seq
MIRT1486510	hsa-miR-510	CLIP-seq
MIRT1486511	hsa-miR-512-5p	CLIP-seq
MIRT1486512	hsa-miR-544	CLIP-seq
MIRT1486513	hsa-miR-545	CLIP-seq
MIRT1486514	hsa-miR-548c-3p	CLIP-seq
MIRT1486515	hsa-miR-554	CLIP-seq
MIRT1486516	hsa-miR-583	CLIP-seq
MIRT1486517	hsa-miR-769-5p	CLIP-seq
MIRT1486518	hsa-miR-876-3p	CLIP-seq
MIRT1486519	hsa-miR-98	CLIP-seq
MIRT1486469	hsa-miR-1184	CLIP-seq
MIRT1486470	hsa-miR-1205	CLIP-seq
MIRT1486476	hsa-miR-2114	CLIP-seq
MIRT1486477	hsa-miR-2964a-3p	CLIP-seq
MIRT1486483	hsa-miR-3158-5p	CLIP-seq
MIRT2146299	hsa-miR-3165	CLIP-seq
MIRT1486484	hsa-miR-3170	CLIP-seq
MIRT2146300	hsa-miR-3622a-3p	CLIP-seq
MIRT2146301	hsa-miR-3622b-3p	CLIP-seq
MIRT1486487	hsa-miR-3664-3p	CLIP-seq
MIRT2146302	hsa-miR-3665	CLIP-seq
MIRT1486488	hsa-miR-3675-5p	CLIP-seq
MIRT1486489	hsa-miR-3682-5p	CLIP-seq
MIRT2146303	hsa-miR-3686	CLIP-seq
MIRT1486490	hsa-miR-3929	CLIP-seq
MIRT1486493	hsa-miR-4291	CLIP-seq
MIRT1486494	hsa-miR-4419b	CLIP-seq
MIRT1486495	hsa-miR-4433	CLIP-seq
MIRT1486498	hsa-miR-4459	CLIP-seq
MIRT1486499	hsa-miR-4478	CLIP-seq
MIRT1486502	hsa-miR-4649-3p	CLIP-seq
MIRT1486503	hsa-miR-4659a-3p	CLIP-seq
MIRT1486504	hsa-miR-4659b-3p	CLIP-seq
MIRT2146304	hsa-miR-4736	CLIP-seq
MIRT2146305	hsa-miR-4742-3p	CLIP-seq
MIRT1486505	hsa-miR-4778-5p	CLIP-seq
MIRT1486506	hsa-miR-4786-5p	CLIP-seq
MIRT1486508	hsa-miR-485-5p	CLIP-seq
MIRT1486510	hsa-miR-510	CLIP-seq
MIRT1486511	hsa-miR-512-5p	CLIP-seq
MIRT1486512	hsa-miR-544	CLIP-seq
MIRT2146306	hsa-miR-544b	CLIP-seq
MIRT1486513	hsa-miR-545	CLIP-seq
MIRT1486517	hsa-miR-769-5p	CLIP-seq
MIRT1486461	hsa-let-7a	CLIP-seq
MIRT1486462	hsa-let-7b	CLIP-seq
MIRT1486463	hsa-let-7c	CLIP-seq
MIRT1486464	hsa-let-7d	CLIP-seq
MIRT1486465	hsa-let-7e	CLIP-seq
MIRT1486466	hsa-let-7f	CLIP-seq
MIRT1486467	hsa-let-7g	CLIP-seq
MIRT1486468	hsa-let-7i	CLIP-seq
MIRT1486469	hsa-miR-1184	CLIP-seq
MIRT1486470	hsa-miR-1205	CLIP-seq
MIRT2366776	hsa-miR-1262	CLIP-seq
MIRT1486472	hsa-miR-1264	CLIP-seq
MIRT1486473	hsa-miR-196a	CLIP-seq
MIRT1486474	hsa-miR-196b	CLIP-seq
MIRT1486475	hsa-miR-2053	CLIP-seq
MIRT1486476	hsa-miR-2114	CLIP-seq
MIRT1486477	hsa-miR-2964a-3p	CLIP-seq
MIRT1486483	hsa-miR-3158-5p	CLIP-seq
MIRT1486485	hsa-miR-323-5p	CLIP-seq
MIRT1486487	hsa-miR-3664-3p	CLIP-seq
MIRT2146303	hsa-miR-3686	CLIP-seq
MIRT1486490	hsa-miR-3929	CLIP-seq
MIRT2366777	hsa-miR-3938	CLIP-seq
MIRT1486492	hsa-miR-4279	CLIP-seq
MIRT1486494	hsa-miR-4419b	CLIP-seq
MIRT1486495	hsa-miR-4433	CLIP-seq
MIRT1486496	hsa-miR-4455	CLIP-seq
MIRT1486497	hsa-miR-4458	CLIP-seq
MIRT1486498	hsa-miR-4459	CLIP-seq
MIRT1486499	hsa-miR-4478	CLIP-seq
MIRT1486500	hsa-miR-4500	CLIP-seq
MIRT1486501	hsa-miR-4539	CLIP-seq
MIRT1486502	hsa-miR-4649-3p	CLIP-seq
MIRT1486503	hsa-miR-4659a-3p	CLIP-seq
MIRT1486504	hsa-miR-4659b-3p	CLIP-seq
MIRT2366778	hsa-miR-4701-3p	CLIP-seq
MIRT2366779	hsa-miR-4716-5p	CLIP-seq
MIRT2146305	hsa-miR-4742-3p	CLIP-seq
MIRT1486505	hsa-miR-4778-5p	CLIP-seq
MIRT1486508	hsa-miR-485-5p	CLIP-seq
MIRT1486510	hsa-miR-510	CLIP-seq
MIRT1486511	hsa-miR-512-5p	CLIP-seq
MIRT2366780	hsa-miR-542-3p	CLIP-seq
MIRT1486512	hsa-miR-544	CLIP-seq
MIRT1486515	hsa-miR-554	CLIP-seq
MIRT1486516	hsa-miR-583	CLIP-seq
MIRT2366781	hsa-miR-630	CLIP-seq
MIRT1486518	hsa-miR-876-3p	CLIP-seq
MIRT1486519	hsa-miR-98	CLIP-seq
MIRT1486461	hsa-let-7a	CLIP-seq
MIRT1486462	hsa-let-7b	CLIP-seq
MIRT1486463	hsa-let-7c	CLIP-seq
MIRT1486464	hsa-let-7d	CLIP-seq
MIRT1486465	hsa-let-7e	CLIP-seq
MIRT1486466	hsa-let-7f	CLIP-seq
MIRT1486467	hsa-let-7g	CLIP-seq
MIRT1486468	hsa-let-7i	CLIP-seq
MIRT1486469	hsa-miR-1184	CLIP-seq
MIRT1486470	hsa-miR-1205	CLIP-seq
MIRT1486473	hsa-miR-196a	CLIP-seq
MIRT1486474	hsa-miR-196b	CLIP-seq
MIRT1486483	hsa-miR-3158-5p	CLIP-seq
MIRT2146299	hsa-miR-3165	CLIP-seq
MIRT2146300	hsa-miR-3622a-3p	CLIP-seq
MIRT2146301	hsa-miR-3622b-3p	CLIP-seq
MIRT2146302	hsa-miR-3665	CLIP-seq
MIRT2396850	hsa-miR-3672	CLIP-seq
MIRT2396851	hsa-miR-3689a-3p	CLIP-seq
MIRT2396852	hsa-miR-3689c	CLIP-seq
MIRT2396853	hsa-miR-4318	CLIP-seq
MIRT1486495	hsa-miR-4433	CLIP-seq
MIRT1486497	hsa-miR-4458	CLIP-seq
MIRT1486498	hsa-miR-4459	CLIP-seq
MIRT1486500	hsa-miR-4500	CLIP-seq
MIRT2396854	hsa-miR-4648	CLIP-seq
MIRT2396855	hsa-miR-4654	CLIP-seq
MIRT2396856	hsa-miR-4728-5p	CLIP-seq
MIRT2146304	hsa-miR-4736	CLIP-seq
MIRT2396857	hsa-miR-4769-5p	CLIP-seq
MIRT1486505	hsa-miR-4778-5p	CLIP-seq
MIRT1486506	hsa-miR-4786-5p	CLIP-seq
MIRT1486512	hsa-miR-544	CLIP-seq
MIRT2146306	hsa-miR-544b	CLIP-seq
MIRT1486517	hsa-miR-769-5p	CLIP-seq
MIRT1486519	hsa-miR-98	CLIP-seq
MIRT2463278	hsa-miR-1231	CLIP-seq
MIRT2463279	hsa-miR-1246	CLIP-seq
MIRT2463280	hsa-miR-149	CLIP-seq
MIRT2463281	hsa-miR-1972	CLIP-seq
MIRT1486476	hsa-miR-2114	CLIP-seq
MIRT2463282	hsa-miR-3064-5p	CLIP-seq
MIRT1486487	hsa-miR-3664-3p	CLIP-seq
MIRT2396851	hsa-miR-3689a-3p	CLIP-seq
MIRT2396852	hsa-miR-3689c	CLIP-seq
MIRT1486490	hsa-miR-3929	CLIP-seq
MIRT2463283	hsa-miR-4288	CLIP-seq
MIRT2396853	hsa-miR-4318	CLIP-seq
MIRT1486494	hsa-miR-4419b	CLIP-seq
MIRT1486495	hsa-miR-4433	CLIP-seq
MIRT1486498	hsa-miR-4459	CLIP-seq
MIRT1486499	hsa-miR-4478	CLIP-seq
MIRT2396854	hsa-miR-4648	CLIP-seq
MIRT1486502	hsa-miR-4649-3p	CLIP-seq
MIRT2463284	hsa-miR-4650-5p	CLIP-seq
MIRT2396855	hsa-miR-4654	CLIP-seq
MIRT2396856	hsa-miR-4728-5p	CLIP-seq
MIRT2396857	hsa-miR-4769-5p	CLIP-seq
MIRT2463285	hsa-miR-4790-3p	CLIP-seq
MIRT2463286	hsa-miR-4794	CLIP-seq
MIRT1486508	hsa-miR-485-5p	CLIP-seq
MIRT1486510	hsa-miR-510	CLIP-seq
MIRT1486511	hsa-miR-512-5p	CLIP-seq
MIRT2463287	hsa-miR-632	CLIP-seq
MIRT2463278	hsa-miR-1231	CLIP-seq
MIRT2463279	hsa-miR-1246	CLIP-seq
MIRT2463280	hsa-miR-149	CLIP-seq
MIRT2463282	hsa-miR-3064-5p	CLIP-seq
MIRT2463283	hsa-miR-4288	CLIP-seq
MIRT2463285	hsa-miR-4790-3p	CLIP-seq
MIRT2463286	hsa-miR-4794	CLIP-seq
MIRT2463287	hsa-miR-632	CLIP-seq
MIRT1486471	hsa-miR-1227	CLIP-seq
MIRT2366776	hsa-miR-1262	CLIP-seq
MIRT2463281	hsa-miR-1972	CLIP-seq
MIRT1486476	hsa-miR-2114	CLIP-seq
MIRT1486477	hsa-miR-2964a-3p	CLIP-seq
MIRT2660415	hsa-miR-3148	CLIP-seq
MIRT2146299	hsa-miR-3165	CLIP-seq
MIRT1486484	hsa-miR-3170	CLIP-seq
MIRT1486485	hsa-miR-323-5p	CLIP-seq
MIRT2146300	hsa-miR-3622a-3p	CLIP-seq
MIRT2146301	hsa-miR-3622b-3p	CLIP-seq
MIRT1486487	hsa-miR-3664-3p	CLIP-seq
MIRT2146302	hsa-miR-3665	CLIP-seq
MIRT2396850	hsa-miR-3672	CLIP-seq
MIRT1486488	hsa-miR-3675-5p	CLIP-seq
MIRT1486489	hsa-miR-3682-5p	CLIP-seq
MIRT2146303	hsa-miR-3686	CLIP-seq
MIRT2396851	hsa-miR-3689a-3p	CLIP-seq
MIRT2396852	hsa-miR-3689c	CLIP-seq
MIRT2660416	hsa-miR-371-5p	CLIP-seq
MIRT2660417	hsa-miR-371b-5p	CLIP-seq
MIRT2660418	hsa-miR-3926	CLIP-seq
MIRT1486490	hsa-miR-3929	CLIP-seq
MIRT2366777	hsa-miR-3938	CLIP-seq
MIRT1486491	hsa-miR-4252	CLIP-seq
MIRT1486493	hsa-miR-4291	CLIP-seq
MIRT2396853	hsa-miR-4318	CLIP-seq
MIRT1486494	hsa-miR-4419b	CLIP-seq
MIRT2660419	hsa-miR-4432	CLIP-seq
MIRT1486495	hsa-miR-4433	CLIP-seq
MIRT1486496	hsa-miR-4455	CLIP-seq
MIRT1486498	hsa-miR-4459	CLIP-seq
MIRT1486499	hsa-miR-4478	CLIP-seq
MIRT2660420	hsa-miR-451b	CLIP-seq
MIRT2396854	hsa-miR-4648	CLIP-seq
MIRT1486502	hsa-miR-4649-3p	CLIP-seq
MIRT2463284	hsa-miR-4650-5p	CLIP-seq
MIRT2396855	hsa-miR-4654	CLIP-seq
MIRT1486503	hsa-miR-4659a-3p	CLIP-seq
MIRT1486504	hsa-miR-4659b-3p	CLIP-seq
MIRT2660421	hsa-miR-4696	CLIP-seq
MIRT2366778	hsa-miR-4701-3p	CLIP-seq
MIRT2366779	hsa-miR-4716-5p	CLIP-seq
MIRT2396856	hsa-miR-4728-5p	CLIP-seq
MIRT2146304	hsa-miR-4736	CLIP-seq
MIRT2146305	hsa-miR-4742-3p	CLIP-seq
MIRT2396857	hsa-miR-4769-5p	CLIP-seq
MIRT1486505	hsa-miR-4778-5p	CLIP-seq
MIRT1486506	hsa-miR-4786-5p	CLIP-seq
MIRT1486507	hsa-miR-4793-3p	CLIP-seq
MIRT1486508	hsa-miR-485-5p	CLIP-seq
MIRT1486510	hsa-miR-510	CLIP-seq
MIRT1486511	hsa-miR-512-5p	CLIP-seq
MIRT2366780	hsa-miR-542-3p	CLIP-seq
MIRT2146306	hsa-miR-544b	CLIP-seq
MIRT1486513	hsa-miR-545	CLIP-seq
MIRT1486514	hsa-miR-548c-3p	CLIP-seq
MIRT2660422	hsa-miR-548s	CLIP-seq
MIRT1486515	hsa-miR-554	CLIP-seq
MIRT2366781	hsa-miR-630	CLIP-seq
MIRT1486517	hsa-miR-769-5p	CLIP-seq
MIRT1486518	hsa-miR-876-3p	CLIP-seq
MIRT2366776	hsa-miR-1262	CLIP-seq
MIRT2463281	hsa-miR-1972	CLIP-seq
MIRT1486476	hsa-miR-2114	CLIP-seq
MIRT1486477	hsa-miR-2964a-3p	CLIP-seq
MIRT2660415	hsa-miR-3148	CLIP-seq
MIRT2146299	hsa-miR-3165	CLIP-seq
MIRT2146300	hsa-miR-3622a-3p	CLIP-seq
MIRT2146301	hsa-miR-3622b-3p	CLIP-seq
MIRT1486487	hsa-miR-3664-3p	CLIP-seq
MIRT2146302	hsa-miR-3665	CLIP-seq
MIRT1486488	hsa-miR-3675-5p	CLIP-seq
MIRT2146303	hsa-miR-3686	CLIP-seq
MIRT2396851	hsa-miR-3689a-3p	CLIP-seq
MIRT2396852	hsa-miR-3689c	CLIP-seq
MIRT2660416	hsa-miR-371-5p	CLIP-seq
MIRT2660417	hsa-miR-371b-5p	CLIP-seq
MIRT1486490	hsa-miR-3929	CLIP-seq
MIRT2366777	hsa-miR-3938	CLIP-seq
MIRT1486491	hsa-miR-4252	CLIP-seq
MIRT2396853	hsa-miR-4318	CLIP-seq
MIRT1486494	hsa-miR-4419b	CLIP-seq
MIRT2660419	hsa-miR-4432	CLIP-seq
MIRT1486495	hsa-miR-4433	CLIP-seq
MIRT1486498	hsa-miR-4459	CLIP-seq
MIRT1486499	hsa-miR-4478	CLIP-seq
MIRT2660420	hsa-miR-451b	CLIP-seq
MIRT2396854	hsa-miR-4648	CLIP-seq
MIRT1486502	hsa-miR-4649-3p	CLIP-seq
MIRT2463284	hsa-miR-4650-5p	CLIP-seq
MIRT2396855	hsa-miR-4654	CLIP-seq
MIRT1486503	hsa-miR-4659a-3p	CLIP-seq
MIRT1486504	hsa-miR-4659b-3p	CLIP-seq
MIRT2660421	hsa-miR-4696	CLIP-seq
MIRT2366778	hsa-miR-4701-3p	CLIP-seq
MIRT2366779	hsa-miR-4716-5p	CLIP-seq
MIRT2396856	hsa-miR-4728-5p	CLIP-seq
MIRT2146304	hsa-miR-4736	CLIP-seq
MIRT2146305	hsa-miR-4742-3p	CLIP-seq
MIRT2396857	hsa-miR-4769-5p	CLIP-seq
MIRT1486505	hsa-miR-4778-5p	CLIP-seq
MIRT1486507	hsa-miR-4793-3p	CLIP-seq
MIRT1486508	hsa-miR-485-5p	CLIP-seq
MIRT1486510	hsa-miR-510	CLIP-seq
MIRT1486511	hsa-miR-512-5p	CLIP-seq
MIRT2366780	hsa-miR-542-3p	CLIP-seq
MIRT2146306	hsa-miR-544b	CLIP-seq
MIRT1486515	hsa-miR-554	CLIP-seq
MIRT2366781	hsa-miR-630	CLIP-seq

Show/Hide all (42)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	19109425, 20190753, 20562859, 23901104, 24554770, 25783203, 26496610, 28013294, 28325809, 29778605, 32296183, 32814053, 33422265, 33961781, 35271311
GO:0005764	Component	Lysosome	IBA
GO:0005764	Component	Lysosome	IEA
GO:0005765	Component	Lysosomal membrane	HDA	17897319
GO:0005765	Component	Lysosomal membrane	IEA
GO:0005768	Component	Endosome	IEA
GO:0005769	Component	Early endosome	IDA	19109425
GO:0005769	Component	Early endosome	IEA
GO:0005770	Component	Late endosome	IDA	19109425
GO:0005776	Component	Autophagosome	IEA
GO:0005776	Component	Autophagosome	ISS
GO:0006886	Process	Intracellular protein transport	IBA
GO:0006914	Process	Autophagy	IEA
GO:0008333	Process	Endosome to lysosome transport	IMP	25783203
GO:0010008	Component	Endosome membrane	TAS
GO:0015031	Process	Protein transport	IEA
GO:0016020	Component	Membrane	IEA
GO:0016192	Process	Vesicle-mediated transport	IBA
GO:0016192	Process	Vesicle-mediated transport	IDA	15790593
GO:0016192	Process	Vesicle-mediated transport	IEA
GO:0030123	Component	AP-3 adaptor complex	IDA	21411634
GO:0030136	Component	Clathrin-coated vesicle	IEA
GO:0030220	Process	Platelet formation	IEA
GO:0030220	Process	Platelet formation	ISS
GO:0030897	Component	HOPS complex	IDA	19109425, 23901104, 24554770, 25783203, 37821429
GO:0030897	Component	HOPS complex	NAS	24554770
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0031902	Component	Late endosome membrane	IEA
GO:0032400	Process	Melanosome localization	IDA	15790593
GO:0032418	Process	Lysosome localization	IDA	15790593
GO:0033263	Component	CORVET complex	IBA
GO:0033263	Component	CORVET complex	IEA
GO:0033263	Component	CORVET complex	NAS	31092635
GO:0034058	Process	Endosomal vesicle fusion	NAS	24554770, 31092635
GO:0035542	Process	Regulation of SNARE complex assembly	NAS	24554770, 31092635
GO:0035751	Process	Regulation of lysosomal lumen pH	IMP	28013294
GO:0043473	Process	Pigmentation	IEA
GO:0048070	Process	Regulation of developmental pigmentation	IEA
GO:0048070	Process	Regulation of developmental pigmentation	ISS
GO:0048471	Component	Perinuclear region of cytoplasm	IDA	19109425
GO:0071439	Component	Clathrin complex	IDA	21411634
GO:0097352	Process	Autophagosome maturation	IMP	24554770, 25783203

MIM	HGNC	e!Ensembl
610034	18179	ENSG00000139719

Q96AX1

Protein name

Vacuolar protein sorting-associated protein 33A (hVPS33A)

Protein function

Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes

PDB

4BX8 , 4BX9

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00995	Sec1	34 → 590	Sec1 family	Family

Sequence

MAAHLSYGRVNLNVLREAVRRELREFLDKCAGSKAIVWDEYLTGPFGLIAQYSLLKEHEV
EKMFTLKGNRLPAADVKNIIFFVRPRLELMDIIAENVLSEDRRGPTRDFHILFVPRRSLL
CEQRLKDLGVLGSFIHREEYSLDLIPFDGDLLSMESEGAFKECYLEGDQTSLYHAAKGLM
TLQALYGTIPQIFGKGECARQVANMMIRMKREFTGSQNSIFPVFDNLLLLDRNVDLLTPL
ATQLTYEGLIDEIYGIQNSYVKLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAEELYAEIR
DKNFNAVGSVLSKKAKIISAAFEERHNAKTVGEIKQFVSQLPHMQAARGSLANHTSIAEL
IKDVTTSEDFFDKLTVEQEFMSGIDTDKVNNYIEDCIAQKHSLIKVLRLVCLQSVCNSGL
KQKVLDYYKREILQTYGYEHILTLHNLEKAGLLKPQTGGRNNYPTIRKTLRLWMDDVNEQ
NPTDISYVYSGYAPLSVRLAQLLSRPGWRSIEEVLRILPGPHFEERQPLPTGLQKKRQPG
ENRVTLIFFLGGVTFAEIAALRFLSQLEDGGTEYVIATTKLMNGTSWIEALMEKPF

Sequence length

596

Interactions

View interactions

	KEGG
	Autophagy - animal Efferocytosis Salmonella infection

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Causal Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Mucopolysaccharidosis-plus syndrome	Likely pathogenic	rs767748011	RCV000415625	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Show/Hide Unknown Diseases (15)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Cholangiocarcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Clear cell carcinoma of kidney	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DESBUQUOIS SYNDROME	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant lymphoma, large B-cell, diffuse	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MUCOPOLYSACCHARIDOSIS-LIKE PLUS DISEASE	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MUCOPOLYSACCHARIDOSIS-LIKE SYNDROME WITH CONGENITAL HEART DEFECTS AND HEMATOPOIETIC DISORDERS	—	Orphanet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Nonpapillary renal cell carcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine carcinosarcoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
VPS33A-related disorder	Benign; Likely benign; Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (26)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Anemia	Anemia	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Arthrogryposis, renal dysfunction, and cholestasis 1	Arthrogryposis, Renal Dysfunction, And Cholestasis	BEFREE	23918659		★★★★★ ★☆☆☆☆ Found in Text Mining only
Blood Platelet Disorders	Platelet disorder	Pubtator	31070736	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital Dysplasia Of The Hip	Developmental dysplasia of the hip	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital Epicanthus	Congenital Epicanthus	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital pectus carinatum	Congenital Pectus Carinatum	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital pectus excavatum	Congenital Pectus Excavatum	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Edema	Edema	Pubtator	36232726	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Focal glomerulosclerosis	Glomerulosclerosis	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Global developmental delay	Developmental Delay	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Hermanski-Pudlak Syndrome	Hermansky-Pudlak Syndrome	LHGDN	12538872		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypertrophic Cardiomyopathy	Hypertrophic cardiomyopathy	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Kidney Diseases	Kidney disease	Pubtator	31070736	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Macroglossia	Macroglossia	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Melanoma	Melanoma	Pubtator	22203954	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Mucopolysaccharidosis I	Mucopolysaccharidosis	Pubtator	31070736, 31936524, 35628659, 36153662, 36232726, 37628632	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Mucopolysaccharidosis-like syndrome with congenital heart defects and hematopoietic disorders	Mucopolysaccharidosis-Like Syndrome With Congenital Heart Defects And Hematopoietic Disorders	Orphanet			★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MUCOPOLYSACCHARIDOSIS-PLUS SYNDROME	MUCOPOLYSACCHARIDOSIS-PLUS SYNDROME	UNIPROT_DG	27547915, 28013294		★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
MUCOPOLYSACCHARIDOSIS-PLUS SYNDROME	MUCOPOLYSACCHARIDOSIS-PLUS SYNDROME	ORPHANET_DG	28013294		★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
MUCOPOLYSACCHARIDOSIS-PLUS SYNDROME	MUCOPOLYSACCHARIDOSIS-PLUS SYNDROME	CTD_human_DG			★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
MUCOPOLYSACCHARIDOSIS-PLUS SYNDROME	MUCOPOLYSACCHARIDOSIS-PLUS SYNDROME	CLINVAR_DG			★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Obesity Abdominal	Obesity	Pubtator	36232726	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Optic Atrophy	Optic Atrophy	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Patent ductus arteriosus	Patent ductus arteriosus	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Pfaundler-Hurler Syndrome	Pfaundler-Hurler Syndrome	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Synophrys	Synophrys	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only

VPS33A (VPS33A core subunit of CORVET and HOPS complexes)