CCDC71 (coiled-coil domain containing 71)

Gene

• Entrez ID: 64925
• Gene name: Coiled-coil domain containing 71
• Gene symbol: CCDC71
• Synonyms (NCBI Gene): -
• Chromosome: 3
• Chromosome location: 3p21.31

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT022489	hsa-miR-124-3p	Microarray	18668037
MIRT052352	hsa-let-7b-5p	CLASH	23622248
MIRT037673	hsa-miR-744-5p	CLASH	23622248
MIRT440990	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440990	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT2195044	hsa-miR-1207-3p	CLIP-seq
MIRT2195045	hsa-miR-1324	CLIP-seq
MIRT2195046	hsa-miR-2355-5p	CLIP-seq
MIRT2195047	hsa-miR-3679-3p	CLIP-seq
MIRT2195048	hsa-miR-378g	CLIP-seq

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q8IV32
• Protein name: Coiled-coil domain-containing protein 71
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15374	CCDC71L	8 → 334	Coiled-coil domain-containing protein 71L	Coiled-coil
  PF15374	CCDC71L	313 → 461	Coiled-coil domain-containing protein 71L	Coiled-coil

• Sequence:

  MSVVVQHVEEKAVHSWSRISTAGKKALEEALLVFNPMSQDLSATEAQLVAFLQGLRDDGF
  QPTILRSGDVYGYSSCTANPPSQTKLQARAPNPTATSPPASAPRTAMRLPAGRATLLPMP
  LSGRLAKASTPALAKHATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLE
  ALVPLKTPMPCLGAKHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLT
  RKGPGAGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVA
  RTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQP
  RGRGRPKGSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSPKAWLGPGT
  AKLLKFRAIKVDRRSSDDEVRQRAQRILRVNLSPVIRLQPLLPYSAV

• Sequence length: 467

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
BEHCET'S SYNDROME	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INSOMNIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Antiphospholipid Syndrome	Antiphospholipid syndrome	Pubtator	37901230	Associate	★☆☆☆☆ Found in Text Mining only
Anxiety	Anxiety disorder	Pubtator	39681175	Associate	★☆☆☆☆ Found in Text Mining only
Hashimoto Disease	Hashimoto disease	Pubtator	37545519	Associate	★☆☆☆☆ Found in Text Mining only
Polycystic Ovary Syndrome	Polycystic ovary syndrome	Pubtator	37545519	Associate	★☆☆☆☆ Found in Text Mining only
Stroke	Stroke	Pubtator	39681175	Associate	★☆☆☆☆ Found in Text Mining only