HRCT1 (histidine rich carboxyl terminus 1)

Gene

• Entrez ID: 646962
• Gene name: Histidine rich carboxyl terminus 1
• Gene symbol: HRCT1
• Synonyms (NCBI Gene): LGLL338, PRO537, UNQ338
• Chromosome: 9
• Chromosome location: 9p13.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT018479	hsa-miR-335-5p	Microarray	18185580
MIRT1054623	hsa-miR-1208	CLIP-seq
MIRT1054624	hsa-miR-219-2-3p	CLIP-seq
MIRT1054625	hsa-miR-23a	CLIP-seq
MIRT1054626	hsa-miR-23b	CLIP-seq
MIRT1054627	hsa-miR-23c	CLIP-seq
MIRT1054628	hsa-miR-2964a-3p	CLIP-seq
MIRT1054629	hsa-miR-3136-5p	CLIP-seq
MIRT1054630	hsa-miR-3192	CLIP-seq
MIRT1054631	hsa-miR-342-3p	CLIP-seq
MIRT1054632	hsa-miR-3944-5p	CLIP-seq
MIRT1054633	hsa-miR-4297	CLIP-seq
MIRT1054634	hsa-miR-4436b-5p	CLIP-seq
MIRT1054635	hsa-miR-4439	CLIP-seq
MIRT1054636	hsa-miR-4457	CLIP-seq
MIRT1054637	hsa-miR-483-5p	CLIP-seq
MIRT1054638	hsa-miR-513b	CLIP-seq
MIRT1054639	hsa-miR-515-5p	CLIP-seq
MIRT1054640	hsa-miR-943	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0016020	Component	Membrane	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q6UXD1
• Protein name: Histidine-rich carboxyl terminus protein 1
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15758	HRCT1	30 → 108	Histidine-rich carboxyl terminus protein 1	Family

• Sequence:

  MLGLLGSTALVGWITGAAVAVLLLLLLLATCLFHGRQDCDVERNRTAAGGNRVRRAQPWP
  FRRRGHLGIFHHHRHPGHVSHVPNVGLHHHHHPRHTPHHLHHHHHPHRHHPRHAR

• Sequence length: 115

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ATRIAL FIBRILLATION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARDIOVASCULAR DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTENSION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
VENOUS THROMBOEMBOLISM	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Carcinoma Ovarian Epithelial	Epithelial ovarian carcinoma	Pubtator	27827314	Associate	★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Cardiovascular Diseases	GWASCAT_DG	30595370		★☆☆☆☆ Found in Text Mining only