Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	644150
Gene name	WAS/WASL interacting protein family member 3
Gene symbol	WIPF3
Synonyms (NCBI Gene)	CR16
Chromosome	7
Chromosome location	7p14.3

122

Show/Hide all (122)

miRTarBase ID	miRNA	Experiments	Reference
MIRT037538	hsa-miR-744-5p	CLASH	23622248
MIRT643945	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT643944	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT643943	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT643942	hsa-miR-6823-5p	HITS-CLIP	23824327
MIRT643941	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT643940	hsa-miR-4685-5p	HITS-CLIP	23824327
MIRT643939	hsa-miR-6837-5p	HITS-CLIP	23824327
MIRT643938	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT643937	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT643936	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT643945	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT643944	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT643943	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT643942	hsa-miR-6823-5p	HITS-CLIP	23824327
MIRT643941	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT643940	hsa-miR-4685-5p	HITS-CLIP	23824327
MIRT643939	hsa-miR-6837-5p	HITS-CLIP	23824327
MIRT643938	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT643937	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT643936	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT1492974	hsa-miR-1182	CLIP-seq
MIRT1492975	hsa-miR-1264	CLIP-seq
MIRT1492976	hsa-miR-1267	CLIP-seq
MIRT1492977	hsa-miR-1273f	CLIP-seq
MIRT1492978	hsa-miR-149	CLIP-seq
MIRT1492979	hsa-miR-197	CLIP-seq
MIRT1492980	hsa-miR-1973	CLIP-seq
MIRT1492981	hsa-miR-19a	CLIP-seq
MIRT1492982	hsa-miR-19b	CLIP-seq
MIRT1492983	hsa-miR-2115	CLIP-seq
MIRT1492984	hsa-miR-24	CLIP-seq
MIRT1492985	hsa-miR-3175	CLIP-seq
MIRT1492986	hsa-miR-3187-3p	CLIP-seq
MIRT1492987	hsa-miR-3614-5p	CLIP-seq
MIRT1492988	hsa-miR-3663-5p	CLIP-seq
MIRT1492989	hsa-miR-3977	CLIP-seq
MIRT1492990	hsa-miR-411	CLIP-seq
MIRT1492991	hsa-miR-4284	CLIP-seq
MIRT1492992	hsa-miR-4423-5p	CLIP-seq
MIRT1492993	hsa-miR-4424	CLIP-seq
MIRT1492994	hsa-miR-4435	CLIP-seq
MIRT1492995	hsa-miR-4682	CLIP-seq
MIRT1492996	hsa-miR-4699-3p	CLIP-seq
MIRT1492997	hsa-miR-4701-5p	CLIP-seq
MIRT1492998	hsa-miR-4716-5p	CLIP-seq
MIRT1492999	hsa-miR-4731-5p	CLIP-seq
MIRT1493000	hsa-miR-4755-3p	CLIP-seq
MIRT1493001	hsa-miR-4781-3p	CLIP-seq
MIRT1493002	hsa-miR-498	CLIP-seq
MIRT1493003	hsa-miR-5096	CLIP-seq
MIRT1493004	hsa-miR-513c	CLIP-seq
MIRT1493005	hsa-miR-514b-5p	CLIP-seq
MIRT1493006	hsa-miR-516a-3p	CLIP-seq
MIRT1493007	hsa-miR-548s	CLIP-seq
MIRT1493008	hsa-miR-582-5p	CLIP-seq
MIRT1493009	hsa-miR-588	CLIP-seq
MIRT1493010	hsa-miR-720	CLIP-seq
MIRT1492979	hsa-miR-197	CLIP-seq
MIRT1492986	hsa-miR-3187-3p	CLIP-seq
MIRT1492988	hsa-miR-3663-5p	CLIP-seq
MIRT1492990	hsa-miR-411	CLIP-seq
MIRT1492994	hsa-miR-4435	CLIP-seq
MIRT1492997	hsa-miR-4701-5p	CLIP-seq
MIRT1492998	hsa-miR-4716-5p	CLIP-seq
MIRT1493000	hsa-miR-4755-3p	CLIP-seq
MIRT1493001	hsa-miR-4781-3p	CLIP-seq
MIRT1493003	hsa-miR-5096	CLIP-seq
MIRT1493007	hsa-miR-548s	CLIP-seq
MIRT1493009	hsa-miR-588	CLIP-seq
MIRT2148661	hsa-miR-129-5p	CLIP-seq
MIRT2148662	hsa-miR-3934	CLIP-seq
MIRT1492992	hsa-miR-4423-5p	CLIP-seq
MIRT1492999	hsa-miR-4731-5p	CLIP-seq
MIRT2148663	hsa-miR-4775	CLIP-seq
MIRT1493002	hsa-miR-498	CLIP-seq
MIRT2148664	hsa-miR-5095	CLIP-seq
MIRT2148665	hsa-miR-552	CLIP-seq
MIRT1492976	hsa-miR-1267	CLIP-seq
MIRT1492979	hsa-miR-197	CLIP-seq
MIRT2369045	hsa-miR-3160-3p	CLIP-seq
MIRT1492990	hsa-miR-411	CLIP-seq
MIRT2369046	hsa-miR-4279	CLIP-seq
MIRT1492992	hsa-miR-4423-5p	CLIP-seq
MIRT1492998	hsa-miR-4716-5p	CLIP-seq
MIRT1493001	hsa-miR-4781-3p	CLIP-seq
MIRT1493003	hsa-miR-5096	CLIP-seq
MIRT2148665	hsa-miR-552	CLIP-seq
MIRT1492974	hsa-miR-1182	CLIP-seq
MIRT1492976	hsa-miR-1267	CLIP-seq
MIRT1492992	hsa-miR-4423-5p	CLIP-seq
MIRT1492993	hsa-miR-4424	CLIP-seq
MIRT1493010	hsa-miR-720	CLIP-seq
MIRT1492974	hsa-miR-1182	CLIP-seq
MIRT2662484	hsa-miR-1254	CLIP-seq
MIRT1492976	hsa-miR-1267	CLIP-seq
MIRT2148661	hsa-miR-129-5p	CLIP-seq
MIRT2662485	hsa-miR-3116	CLIP-seq
MIRT2662486	hsa-miR-3149	CLIP-seq
MIRT1492992	hsa-miR-4423-5p	CLIP-seq
MIRT1492993	hsa-miR-4424	CLIP-seq
MIRT2662487	hsa-miR-4735-5p	CLIP-seq
MIRT2148663	hsa-miR-4775	CLIP-seq
MIRT2662488	hsa-miR-4794	CLIP-seq
MIRT1493002	hsa-miR-498	CLIP-seq
MIRT2662489	hsa-miR-590-3p	CLIP-seq
MIRT2662490	hsa-miR-661	CLIP-seq
MIRT1493010	hsa-miR-720	CLIP-seq
MIRT1492974	hsa-miR-1182	CLIP-seq
MIRT2662484	hsa-miR-1254	CLIP-seq
MIRT1492976	hsa-miR-1267	CLIP-seq
MIRT2148661	hsa-miR-129-5p	CLIP-seq
MIRT2662485	hsa-miR-3116	CLIP-seq
MIRT2662486	hsa-miR-3149	CLIP-seq
MIRT1492992	hsa-miR-4423-5p	CLIP-seq
MIRT1492993	hsa-miR-4424	CLIP-seq
MIRT2662487	hsa-miR-4735-5p	CLIP-seq
MIRT2148663	hsa-miR-4775	CLIP-seq
MIRT2662488	hsa-miR-4794	CLIP-seq
MIRT2662489	hsa-miR-590-3p	CLIP-seq
MIRT2662490	hsa-miR-661	CLIP-seq
MIRT1493010	hsa-miR-720	CLIP-seq

Show/Hide all (19)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003779	Function	Actin binding	IEA
GO:0005515	Function	Protein binding	IPI	23414517, 28514442, 33961781, 35271311
GO:0005737	Component	Cytoplasm	IEA
GO:0005769	Component	Early endosome	IBA
GO:0005769	Component	Early endosome	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006887	Process	Exocytosis	IBA
GO:0007283	Process	Spermatogenesis	IEA
GO:0030154	Process	Cell differentiation	IEA
GO:0032456	Process	Endocytic recycling	IBA
GO:0034314	Process	Arp2/3 complex-mediated actin nucleation	IBA
GO:0034314	Process	Arp2/3 complex-mediated actin nucleation	IEA
GO:0042147	Process	Retrograde transport, endosome to Golgi	IBA
GO:0043014	Function	Alpha-tubulin binding	IBA
GO:0043014	Function	Alpha-tubulin binding	IEA
GO:0043015	Function	Gamma-tubulin binding	IBA
GO:0055037	Component	Recycling endosome	IBA
GO:0071203	Component	WASH complex	IBA
GO:0071203	Component	WASH complex	IEA

MIM	HGNC	e!Ensembl
612432	22004	ENSG00000122574

A6NGB9

Protein name

WAS/WASL-interacting protein family member 3 (Corticosteroids and regional expression protein 16 homolog)

Protein function

May be a regulator of cytoskeletal organization. May have a role in spermatogenesis (By similarity).

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02205	WH2	42 → 69	WH2 motif	Family

Sequence

MPVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLR
KVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGG
KTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPP
PPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPA
SVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYA
SCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQK
KRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQPGGQLRNGSLHIIDDFE
SKFTFHSVEDFPPPDEYKPCQKIYPSKIPRSRTPGPWLQAEAVGQSSDDIKGRNSQLSLK
TLR

Sequence length

483

Interactions

View interactions

	KEGG		Reactome
	Endocytosis Pathogenic Escherichia coli infection Yersinia infection		Regulation of actin dynamics for phagocytic cup formation RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
COLON CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (6)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Alzheimer Disease	Alzheimer disease	Pubtator	40405226	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Atherosclerosis	Atherosclerosis	Pubtator	40405226	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Azoospermia	Azoospermia	BEFREE	21503600		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	28161632		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	28161632		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	BEFREE	28161632		★★★★★ ★☆☆☆☆ Found in Text Mining only

WIPF3 (WAS/WASL interacting protein family member 3)