Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	64225
Gene name	Atlastin GTPase 2
Gene symbol	ATL2
Synonyms (NCBI Gene)	ARL3IP2ARL6IP2ATL-2aip-2atlastin2
Chromosome	2
Chromosome location	2p22.2-p22.1

338

Show/Hide all (338)

miRTarBase ID	miRNA	Experiments	Reference
MIRT020733	hsa-miR-155-5p	Proteomics	18668040
MIRT021152	hsa-miR-186-5p	Sequencing	20371350
MIRT021317	hsa-miR-125a-5p	Sequencing	20371350
MIRT024158	hsa-miR-221-3p	Sequencing	20371350
MIRT028540	hsa-miR-30a-5p	Proteomics	18668040
MIRT031714	hsa-miR-16-5p	Proteomics	18668040
MIRT042321	hsa-miR-484	CLASH	23622248
MIRT705452	hsa-miR-508-5p	HITS-CLIP	23313552
MIRT705451	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT705450	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT705449	hsa-miR-6742-3p	HITS-CLIP	23313552
MIRT705448	hsa-miR-766-3p	HITS-CLIP	23313552
MIRT705447	hsa-miR-4793-3p	HITS-CLIP	23313552
MIRT705446	hsa-miR-6776-5p	HITS-CLIP	23313552
MIRT705445	hsa-miR-661	HITS-CLIP	23313552
MIRT705444	hsa-miR-542-3p	HITS-CLIP	23313552
MIRT705443	hsa-miR-6512-3p	HITS-CLIP	23313552
MIRT705442	hsa-miR-6720-5p	HITS-CLIP	23313552
MIRT705441	hsa-miR-7703	HITS-CLIP	23313552
MIRT705440	hsa-miR-1262	HITS-CLIP	23313552
MIRT705439	hsa-miR-4701-3p	HITS-CLIP	23313552
MIRT705438	hsa-miR-6736-5p	HITS-CLIP	23313552
MIRT441162	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT441162	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT705440	hsa-miR-1262	PAR-CLIP	27292025
MIRT705451	hsa-miR-1273g-3p	PAR-CLIP	27292025
MIRT705439	hsa-miR-4701-3p	PAR-CLIP	27292025
MIRT705447	hsa-miR-4793-3p	PAR-CLIP	27292025
MIRT705452	hsa-miR-508-5p	PAR-CLIP	27292025
MIRT705444	hsa-miR-542-3p	PAR-CLIP	27292025
MIRT705443	hsa-miR-6512-3p	PAR-CLIP	27292025
MIRT705445	hsa-miR-661	PAR-CLIP	27292025
MIRT705442	hsa-miR-6720-5p	PAR-CLIP	27292025
MIRT705438	hsa-miR-6736-5p	PAR-CLIP	27292025
MIRT705449	hsa-miR-6742-3p	PAR-CLIP	27292025
MIRT705446	hsa-miR-6776-5p	PAR-CLIP	27292025
MIRT705450	hsa-miR-6849-3p	PAR-CLIP	27292025
MIRT705448	hsa-miR-766-3p	PAR-CLIP	27292025
MIRT705441	hsa-miR-7703	PAR-CLIP	27292025
MIRT705452	hsa-miR-508-5p	HITS-CLIP	23313552
MIRT705451	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT705450	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT705449	hsa-miR-6742-3p	HITS-CLIP	23313552
MIRT705448	hsa-miR-766-3p	HITS-CLIP	23313552
MIRT705447	hsa-miR-4793-3p	HITS-CLIP	23313552
MIRT705446	hsa-miR-6776-5p	HITS-CLIP	23313552
MIRT705445	hsa-miR-661	HITS-CLIP	23313552
MIRT705444	hsa-miR-542-3p	HITS-CLIP	23313552
MIRT705443	hsa-miR-6512-3p	HITS-CLIP	23313552
MIRT705442	hsa-miR-6720-5p	HITS-CLIP	23313552
MIRT705441	hsa-miR-7703	HITS-CLIP	23313552
MIRT705440	hsa-miR-1262	HITS-CLIP	23313552
MIRT705439	hsa-miR-4701-3p	HITS-CLIP	23313552
MIRT705438	hsa-miR-6736-5p	HITS-CLIP	23313552
MIRT805792	hsa-miR-1296	CLIP-seq
MIRT805793	hsa-miR-139-5p	CLIP-seq
MIRT805794	hsa-miR-183	CLIP-seq
MIRT805795	hsa-miR-186	CLIP-seq
MIRT805796	hsa-miR-18a	CLIP-seq
MIRT805797	hsa-miR-18b	CLIP-seq
MIRT805798	hsa-miR-1908	CLIP-seq
MIRT805799	hsa-miR-200b	CLIP-seq
MIRT805800	hsa-miR-200c	CLIP-seq
MIRT805801	hsa-miR-204	CLIP-seq
MIRT805802	hsa-miR-2054	CLIP-seq
MIRT805803	hsa-miR-211	CLIP-seq
MIRT805804	hsa-miR-219-5p	CLIP-seq
MIRT805805	hsa-miR-224	CLIP-seq
MIRT805806	hsa-miR-2682	CLIP-seq
MIRT805807	hsa-miR-28-5p	CLIP-seq
MIRT805808	hsa-miR-2909	CLIP-seq
MIRT805809	hsa-miR-299-5p	CLIP-seq
MIRT805810	hsa-miR-30a	CLIP-seq
MIRT805811	hsa-miR-30b	CLIP-seq
MIRT805812	hsa-miR-30c	CLIP-seq
MIRT805813	hsa-miR-30d	CLIP-seq
MIRT805814	hsa-miR-30e	CLIP-seq
MIRT805815	hsa-miR-31	CLIP-seq
MIRT805816	hsa-miR-3139	CLIP-seq
MIRT805817	hsa-miR-3171	CLIP-seq
MIRT805818	hsa-miR-33a	CLIP-seq
MIRT805819	hsa-miR-33b	CLIP-seq
MIRT805820	hsa-miR-340	CLIP-seq
MIRT805821	hsa-miR-3611	CLIP-seq
MIRT805822	hsa-miR-3662	CLIP-seq
MIRT805823	hsa-miR-3664-5p	CLIP-seq
MIRT805824	hsa-miR-3682-5p	CLIP-seq
MIRT805825	hsa-miR-3688-5p	CLIP-seq
MIRT805826	hsa-miR-3714	CLIP-seq
MIRT805827	hsa-miR-377	CLIP-seq
MIRT805828	hsa-miR-380	CLIP-seq
MIRT805829	hsa-miR-3938	CLIP-seq
MIRT805830	hsa-miR-3942-5p	CLIP-seq
MIRT805831	hsa-miR-412	CLIP-seq
MIRT805832	hsa-miR-4266	CLIP-seq
MIRT805833	hsa-miR-429	CLIP-seq
MIRT805834	hsa-miR-4328	CLIP-seq
MIRT805835	hsa-miR-4422	CLIP-seq
MIRT805836	hsa-miR-4424	CLIP-seq
MIRT805837	hsa-miR-4436b-3p	CLIP-seq
MIRT805838	hsa-miR-4445	CLIP-seq
MIRT805839	hsa-miR-4452	CLIP-seq
MIRT805840	hsa-miR-4493	CLIP-seq
MIRT805841	hsa-miR-449c	CLIP-seq
MIRT805842	hsa-miR-4652-3p	CLIP-seq
MIRT805843	hsa-miR-4659a-5p	CLIP-seq
MIRT805844	hsa-miR-4659b-5p	CLIP-seq
MIRT805845	hsa-miR-4670-3p	CLIP-seq
MIRT805846	hsa-miR-4676-5p	CLIP-seq
MIRT805847	hsa-miR-4677-3p	CLIP-seq
MIRT805848	hsa-miR-4679	CLIP-seq
MIRT805849	hsa-miR-4696	CLIP-seq
MIRT805850	hsa-miR-4700-3p	CLIP-seq
MIRT805851	hsa-miR-4703-5p	CLIP-seq
MIRT805852	hsa-miR-4704-5p	CLIP-seq
MIRT805853	hsa-miR-4720-3p	CLIP-seq
MIRT805854	hsa-miR-4735-3p	CLIP-seq
MIRT805855	hsa-miR-4755-5p	CLIP-seq
MIRT805856	hsa-miR-4761-3p	CLIP-seq
MIRT805857	hsa-miR-4774-5p	CLIP-seq
MIRT805858	hsa-miR-4780	CLIP-seq
MIRT805859	hsa-miR-4782-3p	CLIP-seq
MIRT805860	hsa-miR-4786-3p	CLIP-seq
MIRT805861	hsa-miR-4804-3p	CLIP-seq
MIRT805862	hsa-miR-508-3p	CLIP-seq
MIRT805863	hsa-miR-5095	CLIP-seq
MIRT805864	hsa-miR-513a-3p	CLIP-seq
MIRT805865	hsa-miR-541	CLIP-seq
MIRT805866	hsa-miR-543	CLIP-seq
MIRT805867	hsa-miR-548a-3p	CLIP-seq
MIRT805868	hsa-miR-548an	CLIP-seq
MIRT805869	hsa-miR-548e	CLIP-seq
MIRT805870	hsa-miR-548f	CLIP-seq
MIRT805871	hsa-miR-548g	CLIP-seq
MIRT805872	hsa-miR-575	CLIP-seq
MIRT805873	hsa-miR-582-5p	CLIP-seq
MIRT805874	hsa-miR-586	CLIP-seq
MIRT805875	hsa-miR-603	CLIP-seq
MIRT805876	hsa-miR-606	CLIP-seq
MIRT805877	hsa-miR-623	CLIP-seq
MIRT805878	hsa-miR-659	CLIP-seq
MIRT805879	hsa-miR-663	CLIP-seq
MIRT805880	hsa-miR-708	CLIP-seq
MIRT805881	hsa-miR-885-3p	CLIP-seq
MIRT805882	hsa-miR-9	CLIP-seq
MIRT805883	hsa-miR-935	CLIP-seq
MIRT1937942	hsa-miR-101	CLIP-seq
MIRT1937943	hsa-miR-103b	CLIP-seq
MIRT1937944	hsa-miR-1193	CLIP-seq
MIRT805792	hsa-miR-1296	CLIP-seq
MIRT805799	hsa-miR-200b	CLIP-seq
MIRT805800	hsa-miR-200c	CLIP-seq
MIRT1937945	hsa-miR-2355-5p	CLIP-seq
MIRT805806	hsa-miR-2682	CLIP-seq
MIRT1937946	hsa-miR-27a	CLIP-seq
MIRT1937947	hsa-miR-27b	CLIP-seq
MIRT805808	hsa-miR-2909	CLIP-seq
MIRT1937948	hsa-miR-3143	CLIP-seq
MIRT1937949	hsa-miR-3163	CLIP-seq
MIRT805820	hsa-miR-340	CLIP-seq
MIRT805826	hsa-miR-3714	CLIP-seq
MIRT1937950	hsa-miR-4289	CLIP-seq
MIRT805833	hsa-miR-429	CLIP-seq
MIRT1937951	hsa-miR-4311	CLIP-seq
MIRT805837	hsa-miR-4436b-3p	CLIP-seq
MIRT805840	hsa-miR-4493	CLIP-seq
MIRT805841	hsa-miR-449c	CLIP-seq
MIRT1937952	hsa-miR-4645-3p	CLIP-seq
MIRT1937953	hsa-miR-4659a-3p	CLIP-seq
MIRT1937954	hsa-miR-4659b-3p	CLIP-seq
MIRT805848	hsa-miR-4679	CLIP-seq
MIRT1937955	hsa-miR-4760-5p	CLIP-seq
MIRT805856	hsa-miR-4761-3p	CLIP-seq
MIRT1937956	hsa-miR-4764-3p	CLIP-seq
MIRT805857	hsa-miR-4774-5p	CLIP-seq
MIRT1937957	hsa-miR-513a-5p	CLIP-seq
MIRT805866	hsa-miR-543	CLIP-seq
MIRT805874	hsa-miR-586	CLIP-seq
MIRT1937942	hsa-miR-101	CLIP-seq
MIRT1937943	hsa-miR-103b	CLIP-seq
MIRT805792	hsa-miR-1296	CLIP-seq
MIRT805793	hsa-miR-139-5p	CLIP-seq
MIRT805798	hsa-miR-1908	CLIP-seq
MIRT805804	hsa-miR-219-5p	CLIP-seq
MIRT805805	hsa-miR-224	CLIP-seq
MIRT805806	hsa-miR-2682	CLIP-seq
MIRT1937946	hsa-miR-27a	CLIP-seq
MIRT1937947	hsa-miR-27b	CLIP-seq
MIRT805808	hsa-miR-2909	CLIP-seq
MIRT805809	hsa-miR-299-5p	CLIP-seq
MIRT805810	hsa-miR-30a	CLIP-seq
MIRT805811	hsa-miR-30b	CLIP-seq
MIRT805812	hsa-miR-30c	CLIP-seq
MIRT805813	hsa-miR-30d	CLIP-seq
MIRT805814	hsa-miR-30e	CLIP-seq
MIRT2177446	hsa-miR-3157-3p	CLIP-seq
MIRT805820	hsa-miR-340	CLIP-seq
MIRT805821	hsa-miR-3611	CLIP-seq
MIRT805823	hsa-miR-3664-5p	CLIP-seq
MIRT805824	hsa-miR-3682-5p	CLIP-seq
MIRT805825	hsa-miR-3688-5p	CLIP-seq
MIRT805826	hsa-miR-3714	CLIP-seq
MIRT805827	hsa-miR-377	CLIP-seq
MIRT805829	hsa-miR-3938	CLIP-seq
MIRT805830	hsa-miR-3942-5p	CLIP-seq
MIRT805831	hsa-miR-412	CLIP-seq
MIRT1937950	hsa-miR-4289	CLIP-seq
MIRT805834	hsa-miR-4328	CLIP-seq
MIRT805835	hsa-miR-4422	CLIP-seq
MIRT805837	hsa-miR-4436b-3p	CLIP-seq
MIRT805838	hsa-miR-4445	CLIP-seq
MIRT805840	hsa-miR-4493	CLIP-seq
MIRT805841	hsa-miR-449c	CLIP-seq
MIRT1937952	hsa-miR-4645-3p	CLIP-seq
MIRT805846	hsa-miR-4676-5p	CLIP-seq
MIRT805847	hsa-miR-4677-3p	CLIP-seq
MIRT805848	hsa-miR-4679	CLIP-seq
MIRT805851	hsa-miR-4703-5p	CLIP-seq
MIRT805852	hsa-miR-4704-5p	CLIP-seq
MIRT805856	hsa-miR-4761-3p	CLIP-seq
MIRT1937956	hsa-miR-4764-3p	CLIP-seq
MIRT805857	hsa-miR-4774-5p	CLIP-seq
MIRT805859	hsa-miR-4782-3p	CLIP-seq
MIRT805860	hsa-miR-4786-3p	CLIP-seq
MIRT2177447	hsa-miR-4796-5p	CLIP-seq
MIRT805862	hsa-miR-508-3p	CLIP-seq
MIRT1937957	hsa-miR-513a-5p	CLIP-seq
MIRT805865	hsa-miR-541	CLIP-seq
MIRT805866	hsa-miR-543	CLIP-seq
MIRT805872	hsa-miR-575	CLIP-seq
MIRT805873	hsa-miR-582-5p	CLIP-seq
MIRT805874	hsa-miR-586	CLIP-seq
MIRT805875	hsa-miR-603	CLIP-seq
MIRT805876	hsa-miR-606	CLIP-seq
MIRT805878	hsa-miR-659	CLIP-seq
MIRT805879	hsa-miR-663	CLIP-seq
MIRT805881	hsa-miR-885-3p	CLIP-seq
MIRT805882	hsa-miR-9	CLIP-seq
MIRT805883	hsa-miR-935	CLIP-seq
MIRT805839	hsa-miR-4452	CLIP-seq
MIRT805866	hsa-miR-543	CLIP-seq
MIRT1937942	hsa-miR-101	CLIP-seq
MIRT1937943	hsa-miR-103b	CLIP-seq
MIRT1937944	hsa-miR-1193	CLIP-seq
MIRT2480903	hsa-miR-1283	CLIP-seq
MIRT2480904	hsa-miR-1323	CLIP-seq
MIRT2480905	hsa-miR-140-3p	CLIP-seq
MIRT2480906	hsa-miR-142-3p	CLIP-seq
MIRT805799	hsa-miR-200b	CLIP-seq
MIRT805800	hsa-miR-200c	CLIP-seq
MIRT805802	hsa-miR-2054	CLIP-seq
MIRT1937945	hsa-miR-2355-5p	CLIP-seq
MIRT2480907	hsa-miR-24	CLIP-seq
MIRT805806	hsa-miR-2682	CLIP-seq
MIRT1937946	hsa-miR-27a	CLIP-seq
MIRT1937947	hsa-miR-27b	CLIP-seq
MIRT2480908	hsa-miR-3124-3p	CLIP-seq
MIRT1937949	hsa-miR-3163	CLIP-seq
MIRT805817	hsa-miR-3171	CLIP-seq
MIRT805818	hsa-miR-33a	CLIP-seq
MIRT805819	hsa-miR-33b	CLIP-seq
MIRT2480909	hsa-miR-3677-5p	CLIP-seq
MIRT805826	hsa-miR-3714	CLIP-seq
MIRT2480910	hsa-miR-374c	CLIP-seq
MIRT805828	hsa-miR-380	CLIP-seq
MIRT805830	hsa-miR-3942-5p	CLIP-seq
MIRT2480911	hsa-miR-4282	CLIP-seq
MIRT2480912	hsa-miR-4284	CLIP-seq
MIRT1937950	hsa-miR-4289	CLIP-seq
MIRT805833	hsa-miR-429	CLIP-seq
MIRT805835	hsa-miR-4422	CLIP-seq
MIRT2480913	hsa-miR-4484	CLIP-seq
MIRT805840	hsa-miR-4493	CLIP-seq
MIRT805841	hsa-miR-449c	CLIP-seq
MIRT1937952	hsa-miR-4645-3p	CLIP-seq
MIRT1937953	hsa-miR-4659a-3p	CLIP-seq
MIRT805843	hsa-miR-4659a-5p	CLIP-seq
MIRT1937954	hsa-miR-4659b-3p	CLIP-seq
MIRT805844	hsa-miR-4659b-5p	CLIP-seq
MIRT805850	hsa-miR-4700-3p	CLIP-seq
MIRT805851	hsa-miR-4703-5p	CLIP-seq
MIRT1937956	hsa-miR-4764-3p	CLIP-seq
MIRT805857	hsa-miR-4774-5p	CLIP-seq
MIRT2480914	hsa-miR-4776-3p	CLIP-seq
MIRT2480915	hsa-miR-511	CLIP-seq
MIRT1937957	hsa-miR-513a-5p	CLIP-seq
MIRT805866	hsa-miR-543	CLIP-seq
MIRT805868	hsa-miR-548an	CLIP-seq
MIRT805871	hsa-miR-548g	CLIP-seq
MIRT2480916	hsa-miR-548o	CLIP-seq
MIRT805874	hsa-miR-586	CLIP-seq
MIRT2480917	hsa-miR-655	CLIP-seq
MIRT1937942	hsa-miR-101	CLIP-seq
MIRT1937943	hsa-miR-103b	CLIP-seq
MIRT1937944	hsa-miR-1193	CLIP-seq
MIRT2480903	hsa-miR-1283	CLIP-seq
MIRT2480904	hsa-miR-1323	CLIP-seq
MIRT2480905	hsa-miR-140-3p	CLIP-seq
MIRT2480906	hsa-miR-142-3p	CLIP-seq
MIRT805799	hsa-miR-200b	CLIP-seq
MIRT805800	hsa-miR-200c	CLIP-seq
MIRT805802	hsa-miR-2054	CLIP-seq
MIRT2480907	hsa-miR-24	CLIP-seq
MIRT805806	hsa-miR-2682	CLIP-seq
MIRT1937946	hsa-miR-27a	CLIP-seq
MIRT1937947	hsa-miR-27b	CLIP-seq
MIRT805817	hsa-miR-3171	CLIP-seq
MIRT805818	hsa-miR-33a	CLIP-seq
MIRT805819	hsa-miR-33b	CLIP-seq
MIRT2480909	hsa-miR-3677-5p	CLIP-seq
MIRT805826	hsa-miR-3714	CLIP-seq
MIRT2480910	hsa-miR-374c	CLIP-seq
MIRT805828	hsa-miR-380	CLIP-seq
MIRT805830	hsa-miR-3942-5p	CLIP-seq
MIRT2480912	hsa-miR-4284	CLIP-seq
MIRT1937950	hsa-miR-4289	CLIP-seq
MIRT805833	hsa-miR-429	CLIP-seq
MIRT805835	hsa-miR-4422	CLIP-seq
MIRT2480913	hsa-miR-4484	CLIP-seq
MIRT805840	hsa-miR-4493	CLIP-seq
MIRT805841	hsa-miR-449c	CLIP-seq
MIRT1937952	hsa-miR-4645-3p	CLIP-seq
MIRT1937953	hsa-miR-4659a-3p	CLIP-seq
MIRT805843	hsa-miR-4659a-5p	CLIP-seq
MIRT1937954	hsa-miR-4659b-3p	CLIP-seq
MIRT805844	hsa-miR-4659b-5p	CLIP-seq
MIRT805850	hsa-miR-4700-3p	CLIP-seq
MIRT805851	hsa-miR-4703-5p	CLIP-seq
MIRT1937956	hsa-miR-4764-3p	CLIP-seq
MIRT805857	hsa-miR-4774-5p	CLIP-seq
MIRT2480914	hsa-miR-4776-3p	CLIP-seq
MIRT2480915	hsa-miR-511	CLIP-seq
MIRT1937957	hsa-miR-513a-5p	CLIP-seq
MIRT805866	hsa-miR-543	CLIP-seq
MIRT805868	hsa-miR-548an	CLIP-seq
MIRT2480916	hsa-miR-548o	CLIP-seq
MIRT805874	hsa-miR-586	CLIP-seq
MIRT2480917	hsa-miR-655	CLIP-seq

Show/Hide all (25)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0003924	Function	GTPase activity	IBA
GO:0003924	Function	GTPase activity	IEA
GO:0005515	Function	Protein binding	IPI	15161933, 19665976, 23969831, 35271311
GO:0005525	Function	GTP binding	IBA
GO:0005525	Function	GTP binding	IEA
GO:0005783	Component	Endoplasmic reticulum	IDA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IDA	18270207
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0006888	Process	Endoplasmic reticulum to Golgi vesicle-mediated transport	IMP	18270207
GO:0007029	Process	Endoplasmic reticulum organization	IBA
GO:0007029	Process	Endoplasmic reticulum organization	IEA
GO:0007030	Process	Golgi organization	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IEA
GO:0016320	Process	Endoplasmic reticulum membrane fusion	IMP	22065636, 27619977
GO:0016787	Function	Hydrolase activity	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0051260	Process	Protein homooligomerization	IBA
GO:0051260	Process	Protein homooligomerization	IEA
GO:0098826	Component	Endoplasmic reticulum tubular network membrane	IDA	22065636, 27619977
GO:0098826	Component	Endoplasmic reticulum tubular network membrane	IEA
GO:0140523	Function	GTPase-dependent fusogenic activity	IDA	22065636
GO:1990809	Process	Endoplasmic reticulum tubular network membrane organization	IMP	18270207, 19665976, 22065636, 27619977

MIM	HGNC	e!Ensembl
609368	24047	ENSG00000119787

Q8NHH9

Protein name

Atlastin-2 (ATL-2) (EC 3.6.5.-) (ADP-ribosylation factor-like protein 6-interacting protein 2)

Protein function

Atlastin-2 (ATL2) is a membrane-anchored GTPase that mediates the GTP-dependent fusion of endoplasmic reticulum (ER) membranes, maintaining the continuous ER network. It facilitates the formation of three-way junctions where ER tubules intersect

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02263	GBP	70 → 341	Guanylate-binding protein, N-terminal domain	Domain
PF02841	GBP_C	343 → 473	Guanylate-binding protein, C-terminal domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in peripheral tissues (at protein level). {ECO:0000269|PubMed:18270207}.

Sequence

MAEGDEAARGQQPHQGLWRRRRTSDPSAAVNHVSSTTSLGENYEDDDLVNSDEVMKKPCP
VQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYN
KDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDS
QSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLM
FLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPG
LKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYI
KIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLD
LKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFA
VMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIGTVIDQIAET
LWEQVLKPLGDNLMEENIRQSVTNSIKAGLTDQVSHHARLKTD

Sequence length

583

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (19)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Acute myeloid leukemia	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cervical cancer	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Clear cell carcinoma of kidney	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colon adenocarcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colorectal cancer	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial prostate cancer	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GILLES DE LA TOURETTE SYNDROME	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INSOMNIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Nonpapillary renal cell carcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thymoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine carcinosarcoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (6)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adult T-Cell Lymphoma/Leukemia	T-Cell Lymphoma/Leukemia	BEFREE	15871724, 2172979		★★★★★ ★☆☆☆☆ Found in Text Mining only
ANOPHTHALMIA AND PULMONARY HYPOPLASIA	Syndromic microphthalmia	BEFREE	28578701		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	38305606	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	GWASCAT_DG	27903959		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, T-Cell	T-cell leukemia	BEFREE	15871724, 2172979		★★★★★ ★☆☆☆☆ Found in Text Mining only
Salivary Gland Neoplasms	Salivary gland neoplasms	Pubtator	33878706	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

ATL2 (atlastin GTPase 2)