Gene Gene information from NCBI Gene database.
Entrez ID 64224
Gene name HERPUD family member 2
Gene symbol HERPUD2
Synonyms (NCBI Gene)
-
Chromosome 7
Chromosome location 7p14.2
miRNA miRNA information provided by mirtarbase database.
466
miRTarBase ID miRNA Experiments Reference
MIRT030766 hsa-miR-21-5p Microarray 18591254
MIRT708110 hsa-miR-1277-5p HITS-CLIP 21572407
MIRT702998 hsa-miR-3163 HITS-CLIP 21572407
MIRT708108 hsa-miR-656-3p HITS-CLIP 21572407
MIRT703006 hsa-miR-340-5p HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
5
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183
GO:0006986 Process Response to unfolded protein IEA
GO:0007283 Process Spermatogenesis IEA
GO:0016020 Component Membrane IEA
GO:0030968 Process Endoplasmic reticulum unfolded protein response IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
620829 21915 ENSG00000122557
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9BSE4
Protein name Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein
Protein function Could be involved in the unfolded protein response (UPR) pathway.
PDB 2KDB
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00240 ubiquitin 12 89 Ubiquitin family Domain
Sequence
MDQSGMEIPVTLIIKAPNQKYSDQTISCFLNWTVGKLKTHLSNVYPSKPLTKDQRLVYSG
RLLPDHLQLKDILRKQDEYHMVHLVCTSR
TPPSSPKSSTNRESHEALASSSNSSSDHSGS
TTPSSGQETLSLAVGSSSEGLRQRTLPQAQTDQAQSHQFPYVMQGNVDNQFPGQAAPPGF
PVYPAFSPLQMLWWQQMYAHQYYMQYQAAVSAQATSNVNPTQPTTSQPLNLAHVPGEEPP
PAPNLVAQENRPMNENVQMNAQGGPVLNEEDFNRDWLDWMYTFSRAAILLSIVYFYSSFS
RFIMVMGAMLLVYLHQAGWFPFRQEGGHQQAPNNNAEVNNDGQNANNLELEEMERLMDDG
LEDESGEDGGEDASAIQRPGLMASAWSFITTFFTSLIPEGPPQVAN
Sequence length 406
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
16
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ARTHRITIS, JUVENILE CTD
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
ATHEROSCLEROSIS GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
ATRIAL FIBRILLATION GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
BRUGADA SYNDROME GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Juvenile arthritis Arthritis CTD_human_DG 19565504
★☆☆☆☆
Found in Text Mining only
Juvenile psoriatic arthritis Juvenile arthritis CTD_human_DG 19565504
★☆☆☆☆
Found in Text Mining only
Juvenile-Onset Still Disease Still Disease CTD_human_DG 19565504
★☆☆☆☆
Found in Text Mining only
Polyarthritis, Juvenile, Rheumatoid Factor Negative Seronegative polyarthritis CTD_human_DG 19565504
★☆☆☆☆
Found in Text Mining only
Polyarthritis, Juvenile, Rheumatoid Factor Positive Polyarthritis, Rheumatoid Factor Positive CTD_human_DG 19565504
★☆☆☆☆
Found in Text Mining only