Gene Gene information from NCBI Gene database.
Entrez ID 63027
Gene name Solute carrier family 22 member 23
Gene symbol SLC22A23
Synonyms (NCBI Gene)
C6orf85
Chromosome 6
Chromosome location 6p25.2
Summary SLC22A23 belongs to a large family of transmembrane proteins that function as uniporters, symporters, and antiporters to transport organic ions across cell membranes (Jacobsson et al., 2007 [PubMed 17714910]).[supplied by OMIM, Mar 2008]
miRNA miRNA information provided by mirtarbase database.
736
miRTarBase ID miRNA Experiments Reference
MIRT043940 hsa-miR-378a-3p CLASH 23622248
MIRT052658 hsa-miR-3127-5p CLASH 23622248
MIRT467915 hsa-miR-520f-3p PAR-CLIP 23592263
MIRT467907 hsa-miR-302c-3p PAR-CLIP 23592263
MIRT467914 hsa-miR-520a-3p PAR-CLIP 23592263
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
6
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25416956, 31515488, 32296183
GO:0005886 Component Plasma membrane IEA
GO:0006811 Process Monoatomic ion transport IEA
GO:0016020 Component Membrane IEA
GO:0022857 Function Transmembrane transporter activity IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
611697 21106 ENSG00000137266
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
A1A5C7
Protein name Solute carrier family 22 member 23
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00083 Sugar_tr 216 629 Sugar (and other) transporter Family
Sequence
Sequence length 686
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
23
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ATRIAL FIBRILLATION GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
ATTENTION DEFICIT HYPERACTIVITY DISORDER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
BILIARY LIVER CIRRHOSIS GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Carcinogenesis Carcinogenesis Pubtator 29703252 Associate
★☆☆☆☆
Found in Text Mining only
Carcinoma of larynx Laryngeal carcinoma BEFREE 29703252
★☆☆☆☆
Found in Text Mining only
Colitis Ulcerative Ulcerative colitis Pubtator 24740203 Associate
★☆☆☆☆
Found in Text Mining only
Crohn Disease Crohn Disease GWASDB_DG 18587394, 21102463
★☆☆☆☆
Found in Text Mining only
Crohn Disease Crohn Disease GWASCAT_DG 21102463, 26192919
★☆☆☆☆
Found in Text Mining only
Endometriosis Endometriosis Pubtator 20935158, 29703252 Associate
★☆☆☆☆
Found in Text Mining only
Endometriosis Endometriosis BEFREE 29703252
★☆☆☆☆
Found in Text Mining only
Infertility Infertility Pubtator 20935158, 29703252 Associate
★☆☆☆☆
Found in Text Mining only
Inflammatory Bowel Diseases Inflammatory Bowel Disease BEFREE 24740203, 29603369, 29703252
★☆☆☆☆
Found in Text Mining only
Inflammatory Bowel Diseases Inflammatory bowel disease Pubtator 24740203, 29703252 Associate
★☆☆☆☆
Found in Text Mining only