ZFAND3 (zinc finger AN1-type containing 3)

Gene

• Entrez ID: 60685
• Gene name: Zinc finger AN1-type containing 3
• Gene symbol: ZFAND3
• Synonyms (NCBI Gene): TEX27
• Chromosome: 6
• Chromosome location: 6p21.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT016738	hsa-miR-335-5p	Microarray	18185580
MIRT027403	hsa-miR-98-5p	Microarray	19088304
MIRT545242	hsa-miR-7844-5p	PAR-CLIP	21572407
MIRT545241	hsa-miR-4712-5p	PAR-CLIP	21572407
MIRT545240	hsa-miR-770-5p	PAR-CLIP	21572407
MIRT545239	hsa-miR-6731-3p	PAR-CLIP	21572407
MIRT545238	hsa-miR-4731-5p	PAR-CLIP	21572407
MIRT545237	hsa-miR-5589-5p	PAR-CLIP	21572407
MIRT545236	hsa-miR-145-5p	PAR-CLIP	21572407
MIRT545235	hsa-miR-5195-3p	PAR-CLIP	21572407
MIRT545242	hsa-miR-7844-5p	PAR-CLIP	21572407
MIRT545241	hsa-miR-4712-5p	PAR-CLIP	21572407
MIRT545240	hsa-miR-770-5p	PAR-CLIP	21572407
MIRT545239	hsa-miR-6731-3p	PAR-CLIP	21572407
MIRT545238	hsa-miR-4731-5p	PAR-CLIP	21572407
MIRT545237	hsa-miR-5589-5p	PAR-CLIP	21572407
MIRT545236	hsa-miR-145-5p	PAR-CLIP	21572407
MIRT545235	hsa-miR-5195-3p	PAR-CLIP	21572407
MIRT1509446	hsa-miR-1207-3p	CLIP-seq
MIRT1509447	hsa-miR-1231	CLIP-seq
MIRT1509448	hsa-miR-1269	CLIP-seq
MIRT1509449	hsa-miR-1269b	CLIP-seq
MIRT1509450	hsa-miR-127-3p	CLIP-seq
MIRT1509451	hsa-miR-1288	CLIP-seq
MIRT1509452	hsa-miR-1305	CLIP-seq
MIRT1509453	hsa-miR-1324	CLIP-seq
MIRT1509454	hsa-miR-142-5p	CLIP-seq
MIRT1509455	hsa-miR-149	CLIP-seq
MIRT1509456	hsa-miR-186	CLIP-seq
MIRT1509457	hsa-miR-204	CLIP-seq
MIRT1509458	hsa-miR-2053	CLIP-seq
MIRT1509459	hsa-miR-211	CLIP-seq
MIRT1509460	hsa-miR-214	CLIP-seq
MIRT1509461	hsa-miR-219-1-3p	CLIP-seq
MIRT1509462	hsa-miR-2355-3p	CLIP-seq
MIRT1509463	hsa-miR-2355-5p	CLIP-seq
MIRT1509464	hsa-miR-3064-5p	CLIP-seq
MIRT1509465	hsa-miR-3138	CLIP-seq
MIRT1509466	hsa-miR-3166	CLIP-seq
MIRT1509467	hsa-miR-337-3p	CLIP-seq
MIRT1509468	hsa-miR-3529	CLIP-seq
MIRT1509469	hsa-miR-3613-3p	CLIP-seq
MIRT1509470	hsa-miR-3619-5p	CLIP-seq
MIRT1509471	hsa-miR-3665	CLIP-seq
MIRT1509472	hsa-miR-3678-3p	CLIP-seq
MIRT1509473	hsa-miR-379	CLIP-seq
MIRT1509474	hsa-miR-3934	CLIP-seq
MIRT1509475	hsa-miR-4291	CLIP-seq
MIRT1509476	hsa-miR-4297	CLIP-seq
MIRT1509477	hsa-miR-4451	CLIP-seq
MIRT1509478	hsa-miR-4455	CLIP-seq
MIRT1509479	hsa-miR-4491	CLIP-seq
MIRT1509480	hsa-miR-4515	CLIP-seq
MIRT1509481	hsa-miR-4646-3p	CLIP-seq
MIRT1509482	hsa-miR-4650-3p	CLIP-seq
MIRT1509483	hsa-miR-4657	CLIP-seq
MIRT1509484	hsa-miR-4722-5p	CLIP-seq
MIRT1509485	hsa-miR-4728-3p	CLIP-seq
MIRT1509486	hsa-miR-4740-5p	CLIP-seq
MIRT1509487	hsa-miR-4755-5p	CLIP-seq
MIRT1509488	hsa-miR-4761-5p	CLIP-seq
MIRT1509489	hsa-miR-4768-3p	CLIP-seq
MIRT1509490	hsa-miR-4771	CLIP-seq
MIRT1509491	hsa-miR-4775	CLIP-seq
MIRT1509492	hsa-miR-4794	CLIP-seq
MIRT1509493	hsa-miR-4797-5p	CLIP-seq
MIRT1509494	hsa-miR-4800-5p	CLIP-seq
MIRT1509495	hsa-miR-5096	CLIP-seq
MIRT1509496	hsa-miR-513b	CLIP-seq
MIRT1509497	hsa-miR-542-3p	CLIP-seq
MIRT1509498	hsa-miR-548a-3p	CLIP-seq
MIRT1509499	hsa-miR-548e	CLIP-seq
MIRT1509500	hsa-miR-548f	CLIP-seq
MIRT1509501	hsa-miR-561	CLIP-seq
MIRT1509502	hsa-miR-569	CLIP-seq
MIRT1509503	hsa-miR-576-3p	CLIP-seq
MIRT1509504	hsa-miR-604	CLIP-seq
MIRT1509505	hsa-miR-609	CLIP-seq
MIRT1509506	hsa-miR-617	CLIP-seq
MIRT1509507	hsa-miR-623	CLIP-seq
MIRT1509508	hsa-miR-624	CLIP-seq
MIRT1509509	hsa-miR-647	CLIP-seq
MIRT1509510	hsa-miR-657	CLIP-seq
MIRT1509511	hsa-miR-676	CLIP-seq
MIRT1509512	hsa-miR-761	CLIP-seq
MIRT1509513	hsa-miR-889	CLIP-seq
MIRT1509514	hsa-miR-922	CLIP-seq
MIRT2153449	hsa-miR-1204	CLIP-seq
MIRT2153450	hsa-miR-1294	CLIP-seq
MIRT1509452	hsa-miR-1305	CLIP-seq
MIRT2153451	hsa-miR-146b-3p	CLIP-seq
MIRT1509455	hsa-miR-149	CLIP-seq
MIRT2153452	hsa-miR-1913	CLIP-seq
MIRT1509460	hsa-miR-214	CLIP-seq
MIRT2153453	hsa-miR-216a	CLIP-seq
MIRT2153454	hsa-miR-2278	CLIP-seq
MIRT2153455	hsa-miR-27a	CLIP-seq
MIRT2153456	hsa-miR-27b	CLIP-seq
MIRT1509464	hsa-miR-3064-5p	CLIP-seq
MIRT2153457	hsa-miR-3124-3p	CLIP-seq
MIRT2153458	hsa-miR-3140-5p	CLIP-seq
MIRT2153459	hsa-miR-3157-3p	CLIP-seq
MIRT2153460	hsa-miR-3173-5p	CLIP-seq
MIRT2153461	hsa-miR-324-3p	CLIP-seq
MIRT2153462	hsa-miR-3609	CLIP-seq
MIRT2153463	hsa-miR-361-3p	CLIP-seq
MIRT2153464	hsa-miR-3615	CLIP-seq
MIRT1509470	hsa-miR-3619-5p	CLIP-seq
MIRT2153465	hsa-miR-3917	CLIP-seq
MIRT2153466	hsa-miR-3926	CLIP-seq
MIRT2153467	hsa-miR-3940-5p	CLIP-seq
MIRT2153468	hsa-miR-3973	CLIP-seq
MIRT2153469	hsa-miR-4282	CLIP-seq
MIRT1509475	hsa-miR-4291	CLIP-seq
MIRT2153470	hsa-miR-4292	CLIP-seq
MIRT2153471	hsa-miR-4305	CLIP-seq
MIRT2153472	hsa-miR-4453	CLIP-seq
MIRT2153473	hsa-miR-4487	CLIP-seq
MIRT2153474	hsa-miR-4503	CLIP-seq
MIRT2153475	hsa-miR-4507	CLIP-seq
MIRT2153476	hsa-miR-451b	CLIP-seq
MIRT2153477	hsa-miR-452	CLIP-seq
MIRT2153478	hsa-miR-4529-5p	CLIP-seq
MIRT2153479	hsa-miR-4538	CLIP-seq
MIRT2153480	hsa-miR-4639-3p	CLIP-seq
MIRT2153481	hsa-miR-4640-5p	CLIP-seq
MIRT2153482	hsa-miR-4676-3p	CLIP-seq
MIRT2153483	hsa-miR-4690-3p	CLIP-seq
MIRT2153484	hsa-miR-4691-3p	CLIP-seq
MIRT2153485	hsa-miR-4693-5p	CLIP-seq
MIRT2153486	hsa-miR-4696	CLIP-seq
MIRT2153487	hsa-miR-4726-5p	CLIP-seq
MIRT2153488	hsa-miR-4730	CLIP-seq
MIRT2153489	hsa-miR-4753-3p	CLIP-seq
MIRT2153490	hsa-miR-4764-3p	CLIP-seq
MIRT2153491	hsa-miR-4768-5p	CLIP-seq
MIRT2153492	hsa-miR-4773	CLIP-seq
MIRT1509491	hsa-miR-4775	CLIP-seq
MIRT2153493	hsa-miR-4777-5p	CLIP-seq
MIRT1509492	hsa-miR-4794	CLIP-seq
MIRT2153494	hsa-miR-486-3p	CLIP-seq
MIRT2153495	hsa-miR-495	CLIP-seq
MIRT2153496	hsa-miR-513a-5p	CLIP-seq
MIRT2153497	hsa-miR-518d-5p	CLIP-seq
MIRT2153498	hsa-miR-519b-5p	CLIP-seq
MIRT2153499	hsa-miR-519c-5p	CLIP-seq
MIRT2153500	hsa-miR-520c-5p	CLIP-seq
MIRT2153501	hsa-miR-520g	CLIP-seq
MIRT2153502	hsa-miR-520h	CLIP-seq
MIRT2153503	hsa-miR-526a	CLIP-seq
MIRT1509497	hsa-miR-542-3p	CLIP-seq
MIRT2153504	hsa-miR-548ah	CLIP-seq
MIRT2153505	hsa-miR-548s	CLIP-seq
MIRT2153506	hsa-miR-578	CLIP-seq
MIRT2153507	hsa-miR-590-3p	CLIP-seq
MIRT2153508	hsa-miR-607	CLIP-seq
MIRT2153509	hsa-miR-671-5p	CLIP-seq
MIRT1509512	hsa-miR-761	CLIP-seq
MIRT2153510	hsa-miR-874	CLIP-seq
MIRT1509514	hsa-miR-922	CLIP-seq
MIRT2373725	hsa-miR-101	CLIP-seq
MIRT2153449	hsa-miR-1204	CLIP-seq
MIRT2373726	hsa-miR-1205	CLIP-seq
MIRT2373727	hsa-miR-1224-3p	CLIP-seq
MIRT1509447	hsa-miR-1231	CLIP-seq
MIRT2373728	hsa-miR-124	CLIP-seq
MIRT1509450	hsa-miR-127-3p	CLIP-seq
MIRT2373729	hsa-miR-1293	CLIP-seq
MIRT2373730	hsa-miR-1301	CLIP-seq
MIRT1509452	hsa-miR-1305	CLIP-seq
MIRT2373731	hsa-miR-139-5p	CLIP-seq
MIRT2373732	hsa-miR-144	CLIP-seq
MIRT2373733	hsa-miR-145	CLIP-seq
MIRT1509455	hsa-miR-149	CLIP-seq
MIRT2373734	hsa-miR-150	CLIP-seq
MIRT2373735	hsa-miR-1909	CLIP-seq
MIRT1509460	hsa-miR-214	CLIP-seq
MIRT2153453	hsa-miR-216a	CLIP-seq
MIRT2373736	hsa-miR-217	CLIP-seq
MIRT1509463	hsa-miR-2355-5p	CLIP-seq
MIRT2373737	hsa-miR-2392	CLIP-seq
MIRT1509464	hsa-miR-3064-5p	CLIP-seq
MIRT2373738	hsa-miR-3119	CLIP-seq
MIRT2373739	hsa-miR-3187-3p	CLIP-seq
MIRT1509467	hsa-miR-337-3p	CLIP-seq
MIRT2373740	hsa-miR-338-3p	CLIP-seq
MIRT1509469	hsa-miR-3613-3p	CLIP-seq
MIRT2153463	hsa-miR-361-3p	CLIP-seq
MIRT1509470	hsa-miR-3619-5p	CLIP-seq
MIRT2373741	hsa-miR-3622a-3p	CLIP-seq
MIRT2373742	hsa-miR-3622b-3p	CLIP-seq
MIRT1509471	hsa-miR-3665	CLIP-seq
MIRT2373743	hsa-miR-3675-5p	CLIP-seq
MIRT2153466	hsa-miR-3926	CLIP-seq
MIRT1509474	hsa-miR-3934	CLIP-seq
MIRT2153469	hsa-miR-4282	CLIP-seq
MIRT1509475	hsa-miR-4291	CLIP-seq
MIRT2373744	hsa-miR-4299	CLIP-seq
MIRT2373745	hsa-miR-4316	CLIP-seq
MIRT2373746	hsa-miR-4323	CLIP-seq
MIRT2373747	hsa-miR-4418	CLIP-seq
MIRT2373748	hsa-miR-4421	CLIP-seq
MIRT2373749	hsa-miR-4436b-5p	CLIP-seq
MIRT2373750	hsa-miR-4456	CLIP-seq
MIRT2373751	hsa-miR-4483	CLIP-seq
MIRT2373752	hsa-miR-450b-5p	CLIP-seq
MIRT2373753	hsa-miR-4519	CLIP-seq
MIRT2153478	hsa-miR-4529-5p	CLIP-seq
MIRT2373754	hsa-miR-4530	CLIP-seq
MIRT2153483	hsa-miR-4690-3p	CLIP-seq
MIRT2153484	hsa-miR-4691-3p	CLIP-seq
MIRT2373755	hsa-miR-4717-5p	CLIP-seq
MIRT2373756	hsa-miR-4747-5p	CLIP-seq
MIRT2373757	hsa-miR-4758-3p	CLIP-seq
MIRT1509488	hsa-miR-4761-5p	CLIP-seq
MIRT1509491	hsa-miR-4775	CLIP-seq
MIRT1509492	hsa-miR-4794	CLIP-seq
MIRT2373758	hsa-miR-5047	CLIP-seq
MIRT2373759	hsa-miR-506	CLIP-seq
MIRT2373760	hsa-miR-507	CLIP-seq
MIRT2373761	hsa-miR-508-5p	CLIP-seq
MIRT2373762	hsa-miR-509-3-5p	CLIP-seq
MIRT2373763	hsa-miR-509-5p	CLIP-seq
MIRT2373764	hsa-miR-511	CLIP-seq
MIRT2373765	hsa-miR-513a-3p	CLIP-seq
MIRT2373766	hsa-miR-541	CLIP-seq
MIRT1509497	hsa-miR-542-3p	CLIP-seq
MIRT2373767	hsa-miR-548ae	CLIP-seq
MIRT2373768	hsa-miR-548aj	CLIP-seq
MIRT2373769	hsa-miR-548am	CLIP-seq
MIRT2373770	hsa-miR-548q	CLIP-seq
MIRT2153505	hsa-miR-548s	CLIP-seq
MIRT2373771	hsa-miR-548x	CLIP-seq
MIRT2373772	hsa-miR-557	CLIP-seq
MIRT2153507	hsa-miR-590-3p	CLIP-seq
MIRT1509504	hsa-miR-604	CLIP-seq
MIRT2373773	hsa-miR-622	CLIP-seq
MIRT1509508	hsa-miR-624	CLIP-seq
MIRT1509509	hsa-miR-647	CLIP-seq
MIRT2373774	hsa-miR-654-5p	CLIP-seq
MIRT1509510	hsa-miR-657	CLIP-seq
MIRT1509512	hsa-miR-761	CLIP-seq
MIRT2373775	hsa-miR-766	CLIP-seq
MIRT2373776	hsa-miR-892b	CLIP-seq
MIRT1509514	hsa-miR-922	CLIP-seq
MIRT2373726	hsa-miR-1205	CLIP-seq
MIRT1509447	hsa-miR-1231	CLIP-seq
MIRT1509455	hsa-miR-149	CLIP-seq
MIRT2373735	hsa-miR-1909	CLIP-seq
MIRT2397338	hsa-miR-199a-5p	CLIP-seq
MIRT2397339	hsa-miR-199b-5p	CLIP-seq
MIRT2373736	hsa-miR-217	CLIP-seq
MIRT1509462	hsa-miR-2355-3p	CLIP-seq
MIRT2397340	hsa-miR-2467-3p	CLIP-seq
MIRT2153455	hsa-miR-27a	CLIP-seq
MIRT2153456	hsa-miR-27b	CLIP-seq
MIRT1509464	hsa-miR-3064-5p	CLIP-seq
MIRT2397341	hsa-miR-3126-3p	CLIP-seq
MIRT2397342	hsa-miR-3158-5p	CLIP-seq
MIRT1509466	hsa-miR-3166	CLIP-seq
MIRT2373743	hsa-miR-3675-5p	CLIP-seq
MIRT1509472	hsa-miR-3678-3p	CLIP-seq
MIRT2397343	hsa-miR-3944-5p	CLIP-seq
MIRT2397344	hsa-miR-4302	CLIP-seq
MIRT2373747	hsa-miR-4418	CLIP-seq
MIRT2153472	hsa-miR-4453	CLIP-seq
MIRT2153479	hsa-miR-4538	CLIP-seq
MIRT1509481	hsa-miR-4646-3p	CLIP-seq
MIRT2153484	hsa-miR-4691-3p	CLIP-seq
MIRT2153488	hsa-miR-4730	CLIP-seq
MIRT1509488	hsa-miR-4761-5p	CLIP-seq
MIRT1509490	hsa-miR-4771	CLIP-seq
MIRT2153492	hsa-miR-4773	CLIP-seq
MIRT1509492	hsa-miR-4794	CLIP-seq
MIRT2373762	hsa-miR-509-3-5p	CLIP-seq
MIRT2373763	hsa-miR-509-5p	CLIP-seq
MIRT2153496	hsa-miR-513a-5p	CLIP-seq
MIRT1509504	hsa-miR-604	CLIP-seq
MIRT1509508	hsa-miR-624	CLIP-seq
MIRT1509509	hsa-miR-647	CLIP-seq
MIRT2397345	hsa-miR-648	CLIP-seq
MIRT2153509	hsa-miR-671-5p	CLIP-seq
MIRT1509511	hsa-miR-676	CLIP-seq
MIRT2441786	hsa-miR-4267	CLIP-seq
MIRT2153476	hsa-miR-451b	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 607455
• HGNC: 18019
• e!Ensembl: ENSG00000156639

Protein

• UniProt ID: Q9H8U3
• Protein name: AN1-type zinc finger protein 3 (Testis-expressed protein 27)
• PDB: 1X4W
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01754	zf-A20	17 → 36	A20-like zinc finger	Family
  PF01428	zf-AN1	157 → 197	AN1-like Zinc finger	Family

• Sequence:

  MGDAGSERSKAPSLPPRCPCGFWGSSKTMNLCSKCFADFQKKQPDDDSAPSTSNSQSDLF
  SEETTSDNNNTSITTPTLSPSQQPLPTELNVTSPSKEECGPCTDTAHVSLITPTKRSCGT
  DSQSENEASPVKRPRLLENTERSEETSRSKQKSRRRCFQCQTKLELVQQELGSCRCGYVF
  CMLHRLPEQHDCTFDHMGRGREEAIMKMVKLDRKVGRSCQRIGEGCS

• Sequence length: 227

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ANDROGENETIC ALOPECIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ARTHRITIS, JUVENILE	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DIABETES MELLITUS, NON-INSULIN-DEPENDENT	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DIABETES MELLITUS, TYPE 2	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INSOMNIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
JUVENILE CHRONIC POLYARTHRITIS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MONOARTICULAR JUVENILE RHEUMATOID ARTHRITIS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PAUCIARTICULAR JUVENILE RHEUMATOID ARTHRITIS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCOLIOSIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Acromegaly	Acromegaly	Pubtator	36435867	Associate	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes mellitus	Pubtator	30907055	Associate	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 2	Diabetes mellitus, type 2	Pubtator	24086726, 25273842, 29451423, 33353041	Associate	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	GWASDB_DG	22158537, 23300278		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	GWASCAT_DG	22158537		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	CTD_human_DG	22158537		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	27862917, 31145772		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Juvenile arthritis	Arthritis	CTD_human_DG	19565504		★☆☆☆☆ Found in Text Mining only
Juvenile psoriatic arthritis	Juvenile arthritis	CTD_human_DG	19565504		★☆☆☆☆ Found in Text Mining only
Juvenile-Onset Still Disease	Still Disease	CTD_human_DG	19565504		★☆☆☆☆ Found in Text Mining only
Polyarthritis, Juvenile, Rheumatoid Factor Negative	Seronegative polyarthritis	CTD_human_DG	19565504		★☆☆☆☆ Found in Text Mining only
Polyarthritis, Juvenile, Rheumatoid Factor Positive	Polyarthritis, Rheumatoid Factor Positive	CTD_human_DG	19565504		★☆☆☆☆ Found in Text Mining only