GPBP1L1 (GC-rich promoter binding protein 1 like 1)

Gene

• Entrez ID: 60313
• Gene name: GC-rich promoter binding protein 1 like 1
• Gene symbol: GPBP1L1
• Synonyms (NCBI Gene): SP192
• Chromosome: 1
• Chromosome location: 1p34.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT021384	hsa-miR-9-5p	Microarray	17612493
MIRT028375	hsa-miR-32-5p	Sequencing	20371350
MIRT029427	hsa-miR-26b-5p	Microarray	19088304
MIRT044129	hsa-miR-30e-5p	CLASH	23622248
MIRT036480	hsa-miR-1226-3p	CLASH	23622248
MIRT279393	hsa-miR-3163	PAR-CLIP	20371350
MIRT460242	hsa-miR-409-5p	PAR-CLIP	20371350
MIRT523457	hsa-miR-548at-5p	PAR-CLIP	20371350
MIRT523456	hsa-miR-561-3p	PAR-CLIP	20371350
MIRT523455	hsa-miR-5580-3p	PAR-CLIP	20371350
MIRT279393	hsa-miR-3163	PAR-CLIP	20371350
MIRT523454	hsa-miR-664b-5p	PAR-CLIP	20371350
MIRT523453	hsa-miR-6892-5p	PAR-CLIP	20371350
MIRT523452	hsa-miR-487a-5p	PAR-CLIP	20371350
MIRT523451	hsa-miR-487b-5p	PAR-CLIP	20371350
MIRT460242	hsa-miR-409-5p	PAR-CLIP	20371350
MIRT564126	hsa-miR-548n	PAR-CLIP	20371350
MIRT564125	hsa-miR-548l	PAR-CLIP	20371350
MIRT560994	hsa-miR-32-3p	PAR-CLIP	20371350
MIRT560993	hsa-miR-329-5p	PAR-CLIP	20371350
MIRT564124	hsa-miR-4686	PAR-CLIP	20371350
MIRT560992	hsa-miR-25-3p	PAR-CLIP	20371350
MIRT028375	hsa-miR-32-5p	PAR-CLIP	20371350
MIRT560991	hsa-miR-363-3p	PAR-CLIP	20371350
MIRT560990	hsa-miR-367-3p	PAR-CLIP	20371350
MIRT560989	hsa-miR-92a-3p	PAR-CLIP	20371350
MIRT560988	hsa-miR-92b-3p	PAR-CLIP	20371350
MIRT564123	hsa-miR-3613-3p	PAR-CLIP	20371350
MIRT560987	hsa-miR-20a-3p	PAR-CLIP	20371350
MIRT560985	hsa-miR-4490	PAR-CLIP	20371350
MIRT564122	hsa-miR-7112-3p	PAR-CLIP	20371350
MIRT564121	hsa-miR-4711-5p	PAR-CLIP	20371350
MIRT560986	hsa-miR-137	PAR-CLIP	20371350
MIRT560984	hsa-miR-544a	PAR-CLIP	20371350
MIRT560983	hsa-miR-6738-3p	PAR-CLIP	20371350
MIRT560994	hsa-miR-32-3p	PAR-CLIP	20371350
MIRT560993	hsa-miR-329-5p	PAR-CLIP	20371350
MIRT560992	hsa-miR-25-3p	PAR-CLIP	20371350
MIRT028375	hsa-miR-32-5p	PAR-CLIP	20371350
MIRT560991	hsa-miR-363-3p	PAR-CLIP	20371350
MIRT560990	hsa-miR-367-3p	PAR-CLIP	20371350
MIRT560989	hsa-miR-92a-3p	PAR-CLIP	20371350
MIRT560988	hsa-miR-92b-3p	PAR-CLIP	20371350
MIRT560987	hsa-miR-20a-3p	PAR-CLIP	20371350
MIRT560985	hsa-miR-4490	PAR-CLIP	20371350
MIRT560986	hsa-miR-137	PAR-CLIP	20371350
MIRT560984	hsa-miR-544a	PAR-CLIP	20371350
MIRT560983	hsa-miR-6738-3p	PAR-CLIP	20371350
MIRT557538	hsa-miR-548c-3p	PAR-CLIP	21572407
MIRT557537	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT557536	hsa-miR-6776-5p	PAR-CLIP	21572407
MIRT557535	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT557534	hsa-miR-3659	PAR-CLIP	21572407
MIRT557533	hsa-miR-6772-5p	PAR-CLIP	21572407
MIRT557532	hsa-miR-4455	PAR-CLIP	21572407
MIRT557531	hsa-miR-609	PAR-CLIP	21572407
MIRT557530	hsa-miR-3650	PAR-CLIP	21572407
MIRT557529	hsa-miR-567	PAR-CLIP	21572407
MIRT557528	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT557527	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT557526	hsa-miR-4658	PAR-CLIP	21572407
MIRT557525	hsa-miR-6790-5p	PAR-CLIP	21572407
MIRT557524	hsa-miR-297	PAR-CLIP	21572407
MIRT557523	hsa-miR-6818-5p	PAR-CLIP	21572407
MIRT523457	hsa-miR-548at-5p	PAR-CLIP	21572407
MIRT523456	hsa-miR-561-3p	PAR-CLIP	21572407
MIRT523455	hsa-miR-5580-3p	PAR-CLIP	21572407
MIRT279393	hsa-miR-3163	PAR-CLIP	21572407
MIRT523454	hsa-miR-664b-5p	PAR-CLIP	21572407
MIRT523453	hsa-miR-6892-5p	PAR-CLIP	21572407
MIRT523452	hsa-miR-487a-5p	PAR-CLIP	21572407
MIRT523451	hsa-miR-487b-5p	PAR-CLIP	21572407
MIRT460242	hsa-miR-409-5p	PAR-CLIP	21572407
MIRT279393	hsa-miR-3163	PAR-CLIP	21572407
MIRT460242	hsa-miR-409-5p	PAR-CLIP	21572407
MIRT523457	hsa-miR-548at-5p	PAR-CLIP	23446348
MIRT523456	hsa-miR-561-3p	PAR-CLIP	23446348
MIRT523455	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT279393	hsa-miR-3163	PAR-CLIP	23446348
MIRT523454	hsa-miR-664b-5p	PAR-CLIP	23446348
MIRT523453	hsa-miR-6892-5p	PAR-CLIP	23446348
MIRT523452	hsa-miR-487a-5p	PAR-CLIP	23446348
MIRT523451	hsa-miR-487b-5p	PAR-CLIP	23446348
MIRT460242	hsa-miR-409-5p	PAR-CLIP	23446348
MIRT279393	hsa-miR-3163	PAR-CLIP	23592263
MIRT460242	hsa-miR-409-5p	PAR-CLIP	23592263
MIRT440535	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440535	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT279393	hsa-miR-3163	PAR-CLIP	20371350
MIRT460242	hsa-miR-409-5p	PAR-CLIP	20371350
MIRT523457	hsa-miR-548at-5p	PAR-CLIP	20371350
MIRT523456	hsa-miR-561-3p	PAR-CLIP	20371350
MIRT523455	hsa-miR-5580-3p	PAR-CLIP	20371350
MIRT279393	hsa-miR-3163	PAR-CLIP	20371350
MIRT523454	hsa-miR-664b-5p	PAR-CLIP	20371350
MIRT523453	hsa-miR-6892-5p	PAR-CLIP	20371350
MIRT523452	hsa-miR-487a-5p	PAR-CLIP	20371350
MIRT523451	hsa-miR-487b-5p	PAR-CLIP	20371350
MIRT460242	hsa-miR-409-5p	PAR-CLIP	20371350
MIRT564126	hsa-miR-548n	PAR-CLIP	20371350
MIRT564125	hsa-miR-548l	PAR-CLIP	20371350
MIRT560994	hsa-miR-32-3p	PAR-CLIP	20371350
MIRT560993	hsa-miR-329-5p	PAR-CLIP	20371350
MIRT564124	hsa-miR-4686	PAR-CLIP	20371350
MIRT560992	hsa-miR-25-3p	PAR-CLIP	20371350
MIRT028375	hsa-miR-32-5p	PAR-CLIP	20371350
MIRT560991	hsa-miR-363-3p	PAR-CLIP	20371350
MIRT560990	hsa-miR-367-3p	PAR-CLIP	20371350
MIRT560989	hsa-miR-92a-3p	PAR-CLIP	20371350
MIRT560988	hsa-miR-92b-3p	PAR-CLIP	20371350
MIRT564123	hsa-miR-3613-3p	PAR-CLIP	20371350
MIRT560987	hsa-miR-20a-3p	PAR-CLIP	20371350
MIRT560985	hsa-miR-4490	PAR-CLIP	20371350
MIRT564122	hsa-miR-7112-3p	PAR-CLIP	20371350
MIRT564121	hsa-miR-4711-5p	PAR-CLIP	20371350
MIRT560986	hsa-miR-137	PAR-CLIP	20371350
MIRT560984	hsa-miR-544a	PAR-CLIP	20371350
MIRT560983	hsa-miR-6738-3p	PAR-CLIP	20371350
MIRT560994	hsa-miR-32-3p	PAR-CLIP	20371350
MIRT560993	hsa-miR-329-5p	PAR-CLIP	20371350
MIRT560992	hsa-miR-25-3p	PAR-CLIP	20371350
MIRT028375	hsa-miR-32-5p	PAR-CLIP	20371350
MIRT560991	hsa-miR-363-3p	PAR-CLIP	20371350
MIRT560990	hsa-miR-367-3p	PAR-CLIP	20371350
MIRT560989	hsa-miR-92a-3p	PAR-CLIP	20371350
MIRT560988	hsa-miR-92b-3p	PAR-CLIP	20371350
MIRT560987	hsa-miR-20a-3p	PAR-CLIP	20371350
MIRT560985	hsa-miR-4490	PAR-CLIP	20371350
MIRT560986	hsa-miR-137	PAR-CLIP	20371350
MIRT560984	hsa-miR-544a	PAR-CLIP	20371350
MIRT560983	hsa-miR-6738-3p	PAR-CLIP	20371350
MIRT557538	hsa-miR-548c-3p	PAR-CLIP	21572407
MIRT557537	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT557536	hsa-miR-6776-5p	PAR-CLIP	21572407
MIRT557535	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT557534	hsa-miR-3659	PAR-CLIP	21572407
MIRT557533	hsa-miR-6772-5p	PAR-CLIP	21572407
MIRT557532	hsa-miR-4455	PAR-CLIP	21572407
MIRT557531	hsa-miR-609	PAR-CLIP	21572407
MIRT557530	hsa-miR-3650	PAR-CLIP	21572407
MIRT557529	hsa-miR-567	PAR-CLIP	21572407
MIRT557528	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT557527	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT557526	hsa-miR-4658	PAR-CLIP	21572407
MIRT557525	hsa-miR-6790-5p	PAR-CLIP	21572407
MIRT557524	hsa-miR-297	PAR-CLIP	21572407
MIRT557523	hsa-miR-6818-5p	PAR-CLIP	21572407
MIRT523457	hsa-miR-548at-5p	PAR-CLIP	21572407
MIRT523456	hsa-miR-561-3p	PAR-CLIP	21572407
MIRT523455	hsa-miR-5580-3p	PAR-CLIP	21572407
MIRT279393	hsa-miR-3163	PAR-CLIP	21572407
MIRT523454	hsa-miR-664b-5p	PAR-CLIP	21572407
MIRT523453	hsa-miR-6892-5p	PAR-CLIP	21572407
MIRT523452	hsa-miR-487a-5p	PAR-CLIP	21572407
MIRT523451	hsa-miR-487b-5p	PAR-CLIP	21572407
MIRT460242	hsa-miR-409-5p	PAR-CLIP	21572407
MIRT279393	hsa-miR-3163	PAR-CLIP	21572407
MIRT460242	hsa-miR-409-5p	PAR-CLIP	21572407
MIRT523457	hsa-miR-548at-5p	PAR-CLIP	23446348
MIRT523456	hsa-miR-561-3p	PAR-CLIP	23446348
MIRT523455	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT279393	hsa-miR-3163	PAR-CLIP	23446348
MIRT523454	hsa-miR-664b-5p	PAR-CLIP	23446348
MIRT523453	hsa-miR-6892-5p	PAR-CLIP	23446348
MIRT523452	hsa-miR-487a-5p	PAR-CLIP	23446348
MIRT523451	hsa-miR-487b-5p	PAR-CLIP	23446348
MIRT460242	hsa-miR-409-5p	PAR-CLIP	23446348
MIRT279393	hsa-miR-3163	PAR-CLIP	23592263
MIRT460242	hsa-miR-409-5p	PAR-CLIP	23592263
MIRT1028502	hsa-miR-1244	CLIP-seq
MIRT1028503	hsa-miR-1273e	CLIP-seq
MIRT1028504	hsa-miR-199a-3p	CLIP-seq
MIRT1028505	hsa-miR-199b-3p	CLIP-seq
MIRT1028506	hsa-miR-3129-5p	CLIP-seq
MIRT1028507	hsa-miR-3140-5p	CLIP-seq
MIRT1028508	hsa-miR-3189-5p	CLIP-seq
MIRT1028509	hsa-miR-3620	CLIP-seq
MIRT1028510	hsa-miR-3679-3p	CLIP-seq
MIRT1028511	hsa-miR-3691-3p	CLIP-seq
MIRT1028512	hsa-miR-371b-3p	CLIP-seq
MIRT1028513	hsa-miR-3922-5p	CLIP-seq
MIRT1028514	hsa-miR-411	CLIP-seq
MIRT1028515	hsa-miR-4427	CLIP-seq
MIRT1028516	hsa-miR-4446-3p	CLIP-seq
MIRT1028517	hsa-miR-4492	CLIP-seq
MIRT1028518	hsa-miR-4498	CLIP-seq
MIRT1028519	hsa-miR-4677-3p	CLIP-seq
MIRT1028520	hsa-miR-4718	CLIP-seq
MIRT1028521	hsa-miR-4729	CLIP-seq
MIRT1028522	hsa-miR-4758-3p	CLIP-seq
MIRT1028523	hsa-miR-491-3p	CLIP-seq
MIRT1028524	hsa-miR-513a-5p	CLIP-seq
MIRT1028525	hsa-miR-561	CLIP-seq
MIRT1028526	hsa-miR-616	CLIP-seq
MIRT1028527	hsa-miR-762	CLIP-seq
MIRT1028503	hsa-miR-1273e	CLIP-seq
MIRT1028507	hsa-miR-3140-5p	CLIP-seq
MIRT1028509	hsa-miR-3620	CLIP-seq
MIRT1028513	hsa-miR-3922-5p	CLIP-seq
MIRT1028515	hsa-miR-4427	CLIP-seq
MIRT1028526	hsa-miR-616	CLIP-seq
MIRT2442225	hsa-miR-3941	CLIP-seq
MIRT2442226	hsa-miR-466	CLIP-seq
MIRT2442227	hsa-miR-4672	CLIP-seq
MIRT2442228	hsa-miR-4731-3p	CLIP-seq
MIRT2442229	hsa-miR-4801	CLIP-seq
MIRT1028502	hsa-miR-1244	CLIP-seq
MIRT1028504	hsa-miR-199a-3p	CLIP-seq
MIRT1028505	hsa-miR-199b-3p	CLIP-seq
MIRT2541813	hsa-miR-203	CLIP-seq
MIRT2541814	hsa-miR-216a	CLIP-seq
MIRT1028506	hsa-miR-3129-5p	CLIP-seq
MIRT2541815	hsa-miR-3148	CLIP-seq
MIRT2541816	hsa-miR-337-3p	CLIP-seq
MIRT2541817	hsa-miR-342-3p	CLIP-seq
MIRT2541818	hsa-miR-3607-3p	CLIP-seq
MIRT1028510	hsa-miR-3679-3p	CLIP-seq
MIRT2541819	hsa-miR-3685	CLIP-seq
MIRT2541820	hsa-miR-3686	CLIP-seq
MIRT2541821	hsa-miR-3689a-5p	CLIP-seq
MIRT2541822	hsa-miR-3689b	CLIP-seq
MIRT2541823	hsa-miR-3689e	CLIP-seq
MIRT2541824	hsa-miR-3689f	CLIP-seq
MIRT1028511	hsa-miR-3691-3p	CLIP-seq
MIRT2541825	hsa-miR-384	CLIP-seq
MIRT2442225	hsa-miR-3941	CLIP-seq
MIRT2541826	hsa-miR-409-3p	CLIP-seq
MIRT2442226	hsa-miR-466	CLIP-seq
MIRT2442227	hsa-miR-4672	CLIP-seq
MIRT2541827	hsa-miR-4698	CLIP-seq
MIRT1028520	hsa-miR-4718	CLIP-seq
MIRT2541828	hsa-miR-4719	CLIP-seq
MIRT2442228	hsa-miR-4731-3p	CLIP-seq
MIRT2442229	hsa-miR-4801	CLIP-seq
MIRT1028523	hsa-miR-491-3p	CLIP-seq
MIRT1028502	hsa-miR-1244	CLIP-seq
MIRT1028504	hsa-miR-199a-3p	CLIP-seq
MIRT1028505	hsa-miR-199b-3p	CLIP-seq
MIRT2541813	hsa-miR-203	CLIP-seq
MIRT2541814	hsa-miR-216a	CLIP-seq
MIRT1028506	hsa-miR-3129-5p	CLIP-seq
MIRT2541815	hsa-miR-3148	CLIP-seq
MIRT2541816	hsa-miR-337-3p	CLIP-seq
MIRT2541817	hsa-miR-342-3p	CLIP-seq
MIRT2541818	hsa-miR-3607-3p	CLIP-seq
MIRT1028510	hsa-miR-3679-3p	CLIP-seq
MIRT2541819	hsa-miR-3685	CLIP-seq
MIRT2541820	hsa-miR-3686	CLIP-seq
MIRT2541821	hsa-miR-3689a-5p	CLIP-seq
MIRT2541822	hsa-miR-3689b	CLIP-seq
MIRT2541823	hsa-miR-3689e	CLIP-seq
MIRT2541824	hsa-miR-3689f	CLIP-seq
MIRT1028511	hsa-miR-3691-3p	CLIP-seq
MIRT2541825	hsa-miR-384	CLIP-seq
MIRT2442225	hsa-miR-3941	CLIP-seq
MIRT2541826	hsa-miR-409-3p	CLIP-seq
MIRT2442226	hsa-miR-466	CLIP-seq
MIRT2442227	hsa-miR-4672	CLIP-seq
MIRT2541827	hsa-miR-4698	CLIP-seq
MIRT1028520	hsa-miR-4718	CLIP-seq
MIRT2541828	hsa-miR-4719	CLIP-seq
MIRT2442228	hsa-miR-4731-3p	CLIP-seq
MIRT2442229	hsa-miR-4801	CLIP-seq
MIRT1028523	hsa-miR-491-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IEA
GO:0003723	Function	RNA binding	IEA
GO:0005515	Function	Protein binding	IPI	16189514, 28514442, 32296183, 32814053, 33961781
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006351	Process	DNA-templated transcription	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IBA
GO:0045893	Process	Positive regulation of DNA-templated transcription	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q9HC44
• Protein name: Vasculin-like protein 1 (GC-rich promoter-binding protein 1-like 1)
• Protein function: Possible transcription factor.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15337	Vasculin	378 → 471	Vascular protein family Vasculin-like 1	Family

• Sequence:

  MAQHDFVPAWLNFSTPQSAKSPTATFEKHGEHLPRGEGRFGVSRRRHNSSDGFFNNGPLR
  TAGDSWHQPSLFRHDSVDSGVSKGAYAGITGNPSGWHSSSRGHDGMSQRSGGGTGNHRHW
  NGSFHSRKGCAFQEKPPMEIREEKKEDKVEKLQFEEEDFPSLNPEAGKQHQPCRPIGTPS
  GVWENPPSAKQPSKMLVIKKVSKEDPAAAFSAAFTSPGSHHANGNKLSSVVPSVYKNLVP
  KPVPPPSKPNAWKANRMEHKSGSLSSSRESAFTSPISVTKPVVLASGAALSSPKESPSST
  TPPIEISSSRLTKLTRRTTDRKSEFLKTLKDDRNGDFSENRDCDKLEDLEDNSTPEPKEN
  GEEGCHQNGLALPVVEEGEVLSHSLEAEHRLLKAMGWQEYPENDENCLPLTEDELKEFHM
  KTEQLRRNGFGKNGFLQSRSSSLFSPWRSTCKAEFEDSDTETSSSETSDDDAWK

• Sequence length: 474

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
HEARING LOSS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations