RGS16 (regulator of G protein signaling 16)

Gene

• Entrez ID: 6004
• Gene name: Regulator of G protein signaling 16
• Gene symbol: RGS16
• Synonyms (NCBI Gene): A28-RGS14, A28-RGS14P, RGS-R
• Chromosome: 1
• Chromosome location: 1q25.3
• Summary: The protein encoded by this gene belongs to the `regulator of G protein signaling` family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in th

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT017280	hsa-miR-335-5p	Microarray	18185580
MIRT027511	hsa-miR-98-5p	Microarray	19088304
MIRT048122	hsa-miR-197-3p	CLASH	23622248
MIRT469304	hsa-miR-494-3p	PAR-CLIP	23592263
MIRT469303	hsa-miR-4450	PAR-CLIP	23592263
MIRT469302	hsa-miR-548aw	PAR-CLIP	23592263
MIRT469301	hsa-miR-518a-5p	PAR-CLIP	23592263
MIRT469300	hsa-miR-527	PAR-CLIP	23592263
MIRT469299	hsa-miR-6857-5p	PAR-CLIP	23592263
MIRT726747	hsa-miR-181a-5p	HITS-CLIP	22473208
MIRT726746	hsa-miR-181b-5p	HITS-CLIP	22473208
MIRT726745	hsa-miR-181c-5p	HITS-CLIP	22473208
MIRT726744	hsa-miR-181d-5p	HITS-CLIP	22473208
MIRT726747	hsa-miR-181a-5p	Luciferase reporter assay, qRT-PCR, Western blot	26013170
MIRT726747	hsa-miR-181a-5p	Luciferase reporter assay, qRT-PCR, Western blot	26013170
MIRT734888	hsa-miR-320a	RNA-seq, qRT-PCR	31801218
MIRT469304	hsa-miR-494-3p	PAR-CLIP	23592263
MIRT469303	hsa-miR-4450	PAR-CLIP	23592263
MIRT469302	hsa-miR-548aw	PAR-CLIP	23592263
MIRT469301	hsa-miR-518a-5p	PAR-CLIP	23592263
MIRT469300	hsa-miR-527	PAR-CLIP	23592263
MIRT469299	hsa-miR-6857-5p	PAR-CLIP	23592263
MIRT1304162	hsa-let-7a	CLIP-seq
MIRT1304163	hsa-let-7b	CLIP-seq
MIRT1304164	hsa-let-7c	CLIP-seq
MIRT1304165	hsa-let-7d	CLIP-seq
MIRT1304166	hsa-let-7e	CLIP-seq
MIRT1304167	hsa-let-7f	CLIP-seq
MIRT1304168	hsa-let-7g	CLIP-seq
MIRT1304169	hsa-let-7i	CLIP-seq
MIRT1304170	hsa-miR-122	CLIP-seq
MIRT1304171	hsa-miR-181a	CLIP-seq
MIRT1304172	hsa-miR-181b	CLIP-seq
MIRT1304173	hsa-miR-181c	CLIP-seq
MIRT1304174	hsa-miR-181d	CLIP-seq
MIRT1304175	hsa-miR-188-3p	CLIP-seq
MIRT1304176	hsa-miR-1915	CLIP-seq
MIRT1304177	hsa-miR-1976	CLIP-seq
MIRT1304178	hsa-miR-216a	CLIP-seq
MIRT1304179	hsa-miR-216b	CLIP-seq
MIRT1304180	hsa-miR-2276	CLIP-seq
MIRT1304181	hsa-miR-28-5p	CLIP-seq
MIRT1304182	hsa-miR-2861	CLIP-seq
MIRT1304183	hsa-miR-298	CLIP-seq
MIRT1304184	hsa-miR-31	CLIP-seq
MIRT1304185	hsa-miR-3123	CLIP-seq
MIRT1304186	hsa-miR-3139	CLIP-seq
MIRT1304187	hsa-miR-3141	CLIP-seq
MIRT1304188	hsa-miR-3155	CLIP-seq
MIRT1304189	hsa-miR-3155b	CLIP-seq
MIRT1304190	hsa-miR-3176	CLIP-seq
MIRT1304191	hsa-miR-338-5p	CLIP-seq
MIRT1304192	hsa-miR-3529	CLIP-seq
MIRT1304193	hsa-miR-3652	CLIP-seq
MIRT1304194	hsa-miR-3659	CLIP-seq
MIRT1304195	hsa-miR-3660	CLIP-seq
MIRT1304196	hsa-miR-3670	CLIP-seq
MIRT1304197	hsa-miR-3675-5p	CLIP-seq
MIRT1304198	hsa-miR-3678-3p	CLIP-seq
MIRT1304199	hsa-miR-3690	CLIP-seq
MIRT1304200	hsa-miR-370	CLIP-seq
MIRT1304201	hsa-miR-379	CLIP-seq
MIRT1304202	hsa-miR-3922-3p	CLIP-seq
MIRT1304203	hsa-miR-3925-3p	CLIP-seq
MIRT1304204	hsa-miR-3925-5p	CLIP-seq
MIRT1304205	hsa-miR-3927	CLIP-seq
MIRT1304206	hsa-miR-3929	CLIP-seq
MIRT1304207	hsa-miR-425	CLIP-seq
MIRT1304208	hsa-miR-4254	CLIP-seq
MIRT1304209	hsa-miR-4257	CLIP-seq
MIRT1304210	hsa-miR-4262	CLIP-seq
MIRT1304211	hsa-miR-4419b	CLIP-seq
MIRT1304212	hsa-miR-4430	CLIP-seq
MIRT1304213	hsa-miR-4433	CLIP-seq
MIRT1304214	hsa-miR-4438	CLIP-seq
MIRT1304215	hsa-miR-4451	CLIP-seq
MIRT1304216	hsa-miR-4458	CLIP-seq
MIRT1304217	hsa-miR-4470	CLIP-seq
MIRT1304218	hsa-miR-4478	CLIP-seq
MIRT1304219	hsa-miR-4490	CLIP-seq
MIRT1304220	hsa-miR-4500	CLIP-seq
MIRT1304221	hsa-miR-4520a-3p	CLIP-seq
MIRT1304222	hsa-miR-4526	CLIP-seq
MIRT1304223	hsa-miR-4638-3p	CLIP-seq
MIRT1304224	hsa-miR-4650-3p	CLIP-seq
MIRT1304225	hsa-miR-4663	CLIP-seq
MIRT1304226	hsa-miR-4666-3p	CLIP-seq
MIRT1304227	hsa-miR-4685-5p	CLIP-seq
MIRT1304228	hsa-miR-4705	CLIP-seq
MIRT1304229	hsa-miR-4708-3p	CLIP-seq
MIRT1304230	hsa-miR-4712-5p	CLIP-seq
MIRT1304231	hsa-miR-4728-3p	CLIP-seq
MIRT1304232	hsa-miR-4773	CLIP-seq
MIRT1304233	hsa-miR-4774-5p	CLIP-seq
MIRT1304234	hsa-miR-484	CLIP-seq
MIRT1304235	hsa-miR-486-3p	CLIP-seq
MIRT1304236	hsa-miR-489	CLIP-seq
MIRT1304237	hsa-miR-494	CLIP-seq
MIRT1304238	hsa-miR-515-5p	CLIP-seq
MIRT1304239	hsa-miR-532-3p	CLIP-seq
MIRT1304240	hsa-miR-548aa	CLIP-seq
MIRT1304241	hsa-miR-676	CLIP-seq
MIRT1304242	hsa-miR-708	CLIP-seq
MIRT1304243	hsa-miR-765	CLIP-seq
MIRT1304244	hsa-miR-766	CLIP-seq
MIRT1304245	hsa-miR-770-5p	CLIP-seq
MIRT1304246	hsa-miR-936	CLIP-seq
MIRT1304247	hsa-miR-98	CLIP-seq
MIRT1304241	hsa-miR-676	CLIP-seq
MIRT1304241	hsa-miR-676	CLIP-seq
MIRT1304241	hsa-miR-676	CLIP-seq
MIRT1304241	hsa-miR-676	CLIP-seq
MIRT1304241	hsa-miR-676	CLIP-seq
MIRT1304162	hsa-let-7a	CLIP-seq
MIRT1304163	hsa-let-7b	CLIP-seq
MIRT1304164	hsa-let-7c	CLIP-seq
MIRT1304165	hsa-let-7d	CLIP-seq
MIRT1304166	hsa-let-7e	CLIP-seq
MIRT1304167	hsa-let-7f	CLIP-seq
MIRT1304168	hsa-let-7g	CLIP-seq
MIRT1304169	hsa-let-7i	CLIP-seq
MIRT2090127	hsa-miR-1178	CLIP-seq
MIRT1304170	hsa-miR-122	CLIP-seq
MIRT2090128	hsa-miR-1237	CLIP-seq
MIRT2090129	hsa-miR-1238	CLIP-seq
MIRT2090130	hsa-miR-1248	CLIP-seq
MIRT2090131	hsa-miR-1304	CLIP-seq
MIRT2090132	hsa-miR-136	CLIP-seq
MIRT2090133	hsa-miR-144	CLIP-seq
MIRT2090134	hsa-miR-146a	CLIP-seq
MIRT2090135	hsa-miR-146b-5p	CLIP-seq
MIRT1304171	hsa-miR-181a	CLIP-seq
MIRT1304172	hsa-miR-181b	CLIP-seq
MIRT1304173	hsa-miR-181c	CLIP-seq
MIRT1304174	hsa-miR-181d	CLIP-seq
MIRT1304175	hsa-miR-188-3p	CLIP-seq
MIRT1304176	hsa-miR-1915	CLIP-seq
MIRT2090136	hsa-miR-2115	CLIP-seq
MIRT2090137	hsa-miR-2355-5p	CLIP-seq
MIRT1304182	hsa-miR-2861	CLIP-seq
MIRT1304185	hsa-miR-3123	CLIP-seq
MIRT2090138	hsa-miR-3124-3p	CLIP-seq
MIRT2090139	hsa-miR-3127-3p	CLIP-seq
MIRT1304187	hsa-miR-3141	CLIP-seq
MIRT2090140	hsa-miR-3150b-3p	CLIP-seq
MIRT1304188	hsa-miR-3155	CLIP-seq
MIRT1304189	hsa-miR-3155b	CLIP-seq
MIRT2090141	hsa-miR-3183	CLIP-seq
MIRT2090142	hsa-miR-3194-3p	CLIP-seq
MIRT2090143	hsa-miR-338-3p	CLIP-seq
MIRT1304191	hsa-miR-338-5p	CLIP-seq
MIRT1304192	hsa-miR-3529	CLIP-seq
MIRT1304194	hsa-miR-3659	CLIP-seq
MIRT1304195	hsa-miR-3660	CLIP-seq
MIRT1304200	hsa-miR-370	CLIP-seq
MIRT2090144	hsa-miR-375	CLIP-seq
MIRT2090145	hsa-miR-378g	CLIP-seq
MIRT1304201	hsa-miR-379	CLIP-seq
MIRT1304203	hsa-miR-3925-3p	CLIP-seq
MIRT1304204	hsa-miR-3925-5p	CLIP-seq
MIRT1304205	hsa-miR-3927	CLIP-seq
MIRT1304206	hsa-miR-3929	CLIP-seq
MIRT1304209	hsa-miR-4257	CLIP-seq
MIRT1304210	hsa-miR-4262	CLIP-seq
MIRT2090146	hsa-miR-4268	CLIP-seq
MIRT1304211	hsa-miR-4419b	CLIP-seq
MIRT1304213	hsa-miR-4433	CLIP-seq
MIRT2090147	hsa-miR-4437	CLIP-seq
MIRT1304214	hsa-miR-4438	CLIP-seq
MIRT1304215	hsa-miR-4451	CLIP-seq
MIRT1304216	hsa-miR-4458	CLIP-seq
MIRT1304217	hsa-miR-4470	CLIP-seq
MIRT1304218	hsa-miR-4478	CLIP-seq
MIRT1304219	hsa-miR-4490	CLIP-seq
MIRT2090148	hsa-miR-4496	CLIP-seq
MIRT1304220	hsa-miR-4500	CLIP-seq
MIRT1304222	hsa-miR-4526	CLIP-seq
MIRT2090149	hsa-miR-4530	CLIP-seq
MIRT1304224	hsa-miR-4650-3p	CLIP-seq
MIRT2090150	hsa-miR-4659a-5p	CLIP-seq
MIRT2090151	hsa-miR-4659b-5p	CLIP-seq
MIRT1304225	hsa-miR-4663	CLIP-seq
MIRT1304226	hsa-miR-4666-3p	CLIP-seq
MIRT2090152	hsa-miR-4674	CLIP-seq
MIRT1304227	hsa-miR-4685-5p	CLIP-seq
MIRT2090153	hsa-miR-4689	CLIP-seq
MIRT2090154	hsa-miR-4691-5p	CLIP-seq
MIRT1304230	hsa-miR-4712-5p	CLIP-seq
MIRT2090155	hsa-miR-4722-5p	CLIP-seq
MIRT2090156	hsa-miR-4723-3p	CLIP-seq
MIRT2090157	hsa-miR-4725-5p	CLIP-seq
MIRT2090158	hsa-miR-4742-5p	CLIP-seq
MIRT2090159	hsa-miR-4764-5p	CLIP-seq
MIRT1304233	hsa-miR-4774-5p	CLIP-seq
MIRT2090160	hsa-miR-4776-3p	CLIP-seq
MIRT2090161	hsa-miR-4782-5p	CLIP-seq
MIRT2090162	hsa-miR-4784	CLIP-seq
MIRT2090163	hsa-miR-4800-5p	CLIP-seq
MIRT1304234	hsa-miR-484	CLIP-seq
MIRT2090164	hsa-miR-504	CLIP-seq
MIRT2090165	hsa-miR-511	CLIP-seq
MIRT2090166	hsa-miR-513a-5p	CLIP-seq
MIRT1304238	hsa-miR-515-5p	CLIP-seq
MIRT2090167	hsa-miR-516a-3p	CLIP-seq
MIRT2090168	hsa-miR-552	CLIP-seq
MIRT2090169	hsa-miR-589	CLIP-seq
MIRT2090170	hsa-miR-661	CLIP-seq
MIRT2090171	hsa-miR-665	CLIP-seq
MIRT1304241	hsa-miR-676	CLIP-seq
MIRT2090172	hsa-miR-711	CLIP-seq
MIRT2090173	hsa-miR-760	CLIP-seq
MIRT1304244	hsa-miR-766	CLIP-seq
MIRT2090174	hsa-miR-767-3p	CLIP-seq
MIRT1304245	hsa-miR-770-5p	CLIP-seq
MIRT2090175	hsa-miR-873	CLIP-seq
MIRT1304246	hsa-miR-936	CLIP-seq
MIRT1304247	hsa-miR-98	CLIP-seq
MIRT1304162	hsa-let-7a	CLIP-seq
MIRT1304163	hsa-let-7b	CLIP-seq
MIRT1304164	hsa-let-7c	CLIP-seq
MIRT1304165	hsa-let-7d	CLIP-seq
MIRT1304166	hsa-let-7e	CLIP-seq
MIRT1304167	hsa-let-7f	CLIP-seq
MIRT1304168	hsa-let-7g	CLIP-seq
MIRT1304169	hsa-let-7i	CLIP-seq
MIRT1304171	hsa-miR-181a	CLIP-seq
MIRT1304172	hsa-miR-181b	CLIP-seq
MIRT1304173	hsa-miR-181c	CLIP-seq
MIRT1304174	hsa-miR-181d	CLIP-seq
MIRT1304203	hsa-miR-3925-3p	CLIP-seq
MIRT1304205	hsa-miR-3927	CLIP-seq
MIRT1304209	hsa-miR-4257	CLIP-seq
MIRT1304210	hsa-miR-4262	CLIP-seq
MIRT1304214	hsa-miR-4438	CLIP-seq
MIRT1304215	hsa-miR-4451	CLIP-seq
MIRT1304216	hsa-miR-4458	CLIP-seq
MIRT1304220	hsa-miR-4500	CLIP-seq
MIRT1304230	hsa-miR-4712-5p	CLIP-seq
MIRT1304238	hsa-miR-515-5p	CLIP-seq
MIRT1304244	hsa-miR-766	CLIP-seq
MIRT1304245	hsa-miR-770-5p	CLIP-seq
MIRT1304246	hsa-miR-936	CLIP-seq
MIRT1304247	hsa-miR-98	CLIP-seq
MIRT1304241	hsa-miR-676	CLIP-seq
MIRT1304162	hsa-let-7a	CLIP-seq
MIRT1304163	hsa-let-7b	CLIP-seq
MIRT1304164	hsa-let-7c	CLIP-seq
MIRT1304165	hsa-let-7d	CLIP-seq
MIRT1304166	hsa-let-7e	CLIP-seq
MIRT1304167	hsa-let-7f	CLIP-seq
MIRT1304168	hsa-let-7g	CLIP-seq
MIRT1304169	hsa-let-7i	CLIP-seq
MIRT1304170	hsa-miR-122	CLIP-seq
MIRT2611198	hsa-miR-1285	CLIP-seq
MIRT2611199	hsa-miR-132	CLIP-seq
MIRT1304171	hsa-miR-181a	CLIP-seq
MIRT1304172	hsa-miR-181b	CLIP-seq
MIRT1304173	hsa-miR-181c	CLIP-seq
MIRT1304174	hsa-miR-181d	CLIP-seq
MIRT2611200	hsa-miR-1973	CLIP-seq
MIRT2611201	hsa-miR-212	CLIP-seq
MIRT1304185	hsa-miR-3123	CLIP-seq
MIRT2090140	hsa-miR-3150b-3p	CLIP-seq
MIRT1304188	hsa-miR-3155	CLIP-seq
MIRT1304189	hsa-miR-3155b	CLIP-seq
MIRT2611202	hsa-miR-3187-5p	CLIP-seq
MIRT2611203	hsa-miR-3192	CLIP-seq
MIRT2611204	hsa-miR-326	CLIP-seq
MIRT2611205	hsa-miR-330-5p	CLIP-seq
MIRT1304191	hsa-miR-338-5p	CLIP-seq
MIRT1304192	hsa-miR-3529	CLIP-seq
MIRT1304194	hsa-miR-3659	CLIP-seq
MIRT1304200	hsa-miR-370	CLIP-seq
MIRT2090145	hsa-miR-378g	CLIP-seq
MIRT1304201	hsa-miR-379	CLIP-seq
MIRT1304203	hsa-miR-3925-3p	CLIP-seq
MIRT1304204	hsa-miR-3925-5p	CLIP-seq
MIRT2611206	hsa-miR-3926	CLIP-seq
MIRT1304205	hsa-miR-3927	CLIP-seq
MIRT1304206	hsa-miR-3929	CLIP-seq
MIRT1304209	hsa-miR-4257	CLIP-seq
MIRT1304210	hsa-miR-4262	CLIP-seq
MIRT2611207	hsa-miR-4271	CLIP-seq
MIRT2611208	hsa-miR-4314	CLIP-seq
MIRT1304211	hsa-miR-4419b	CLIP-seq
MIRT2611209	hsa-miR-4432	CLIP-seq
MIRT1304213	hsa-miR-4433	CLIP-seq
MIRT1304214	hsa-miR-4438	CLIP-seq
MIRT1304215	hsa-miR-4451	CLIP-seq
MIRT1304216	hsa-miR-4458	CLIP-seq
MIRT1304217	hsa-miR-4470	CLIP-seq
MIRT2611210	hsa-miR-4475	CLIP-seq
MIRT1304218	hsa-miR-4478	CLIP-seq
MIRT2611211	hsa-miR-4486	CLIP-seq
MIRT1304219	hsa-miR-4490	CLIP-seq
MIRT2090148	hsa-miR-4496	CLIP-seq
MIRT1304220	hsa-miR-4500	CLIP-seq
MIRT2611212	hsa-miR-4522	CLIP-seq
MIRT2611213	hsa-miR-4646-5p	CLIP-seq
MIRT1304224	hsa-miR-4650-3p	CLIP-seq
MIRT1304225	hsa-miR-4663	CLIP-seq
MIRT1304227	hsa-miR-4685-5p	CLIP-seq
MIRT2090153	hsa-miR-4689	CLIP-seq
MIRT1304230	hsa-miR-4712-5p	CLIP-seq
MIRT2611214	hsa-miR-4725-3p	CLIP-seq
MIRT1304232	hsa-miR-4773	CLIP-seq
MIRT1304233	hsa-miR-4774-5p	CLIP-seq
MIRT2611215	hsa-miR-4779	CLIP-seq
MIRT2090162	hsa-miR-4784	CLIP-seq
MIRT1304234	hsa-miR-484	CLIP-seq
MIRT1304238	hsa-miR-515-5p	CLIP-seq
MIRT2611216	hsa-miR-612	CLIP-seq
MIRT2611217	hsa-miR-622	CLIP-seq
MIRT2611218	hsa-miR-7	CLIP-seq
MIRT1304244	hsa-miR-766	CLIP-seq
MIRT1304245	hsa-miR-770-5p	CLIP-seq
MIRT1304246	hsa-miR-936	CLIP-seq
MIRT1304247	hsa-miR-98	CLIP-seq
MIRT1304162	hsa-let-7a	CLIP-seq
MIRT1304163	hsa-let-7b	CLIP-seq
MIRT1304164	hsa-let-7c	CLIP-seq
MIRT1304165	hsa-let-7d	CLIP-seq
MIRT1304166	hsa-let-7e	CLIP-seq
MIRT1304167	hsa-let-7f	CLIP-seq
MIRT1304168	hsa-let-7g	CLIP-seq
MIRT1304169	hsa-let-7i	CLIP-seq
MIRT1304170	hsa-miR-122	CLIP-seq
MIRT2611198	hsa-miR-1285	CLIP-seq
MIRT2090132	hsa-miR-136	CLIP-seq
MIRT1304171	hsa-miR-181a	CLIP-seq
MIRT1304172	hsa-miR-181b	CLIP-seq
MIRT1304173	hsa-miR-181c	CLIP-seq
MIRT1304174	hsa-miR-181d	CLIP-seq
MIRT2611200	hsa-miR-1973	CLIP-seq
MIRT1304185	hsa-miR-3123	CLIP-seq
MIRT2090140	hsa-miR-3150b-3p	CLIP-seq
MIRT1304188	hsa-miR-3155	CLIP-seq
MIRT1304189	hsa-miR-3155b	CLIP-seq
MIRT2611202	hsa-miR-3187-5p	CLIP-seq
MIRT2611204	hsa-miR-326	CLIP-seq
MIRT2611205	hsa-miR-330-5p	CLIP-seq
MIRT1304191	hsa-miR-338-5p	CLIP-seq
MIRT1304192	hsa-miR-3529	CLIP-seq
MIRT1304194	hsa-miR-3659	CLIP-seq
MIRT1304200	hsa-miR-370	CLIP-seq
MIRT2090145	hsa-miR-378g	CLIP-seq
MIRT1304201	hsa-miR-379	CLIP-seq
MIRT1304203	hsa-miR-3925-3p	CLIP-seq
MIRT1304204	hsa-miR-3925-5p	CLIP-seq
MIRT2611206	hsa-miR-3926	CLIP-seq
MIRT1304205	hsa-miR-3927	CLIP-seq
MIRT1304206	hsa-miR-3929	CLIP-seq
MIRT1304209	hsa-miR-4257	CLIP-seq
MIRT1304210	hsa-miR-4262	CLIP-seq
MIRT2689725	hsa-miR-4267	CLIP-seq
MIRT2611207	hsa-miR-4271	CLIP-seq
MIRT1304211	hsa-miR-4419b	CLIP-seq
MIRT2611209	hsa-miR-4432	CLIP-seq
MIRT1304213	hsa-miR-4433	CLIP-seq
MIRT1304214	hsa-miR-4438	CLIP-seq
MIRT1304215	hsa-miR-4451	CLIP-seq
MIRT1304216	hsa-miR-4458	CLIP-seq
MIRT1304217	hsa-miR-4470	CLIP-seq
MIRT2611210	hsa-miR-4475	CLIP-seq
MIRT1304218	hsa-miR-4478	CLIP-seq
MIRT2611211	hsa-miR-4486	CLIP-seq
MIRT1304219	hsa-miR-4490	CLIP-seq
MIRT2090148	hsa-miR-4496	CLIP-seq
MIRT1304220	hsa-miR-4500	CLIP-seq
MIRT2611212	hsa-miR-4522	CLIP-seq
MIRT1304224	hsa-miR-4650-3p	CLIP-seq
MIRT1304225	hsa-miR-4663	CLIP-seq
MIRT1304227	hsa-miR-4685-5p	CLIP-seq
MIRT2090153	hsa-miR-4689	CLIP-seq
MIRT1304230	hsa-miR-4712-5p	CLIP-seq
MIRT2611214	hsa-miR-4725-3p	CLIP-seq
MIRT1304233	hsa-miR-4774-5p	CLIP-seq
MIRT2611215	hsa-miR-4779	CLIP-seq
MIRT2090162	hsa-miR-4784	CLIP-seq
MIRT1304234	hsa-miR-484	CLIP-seq
MIRT1304237	hsa-miR-494	CLIP-seq
MIRT1304238	hsa-miR-515-5p	CLIP-seq
MIRT2611216	hsa-miR-612	CLIP-seq
MIRT2611218	hsa-miR-7	CLIP-seq
MIRT1304244	hsa-miR-766	CLIP-seq
MIRT1304245	hsa-miR-770-5p	CLIP-seq
MIRT1304246	hsa-miR-936	CLIP-seq
MIRT1304247	hsa-miR-98	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003924	Function	GTPase activity	IEA
GO:0003924	Function	GTPase activity	TAS
GO:0005096	Function	GTPase activator activity	IDA	18434541
GO:0005096	Function	GTPase activator activity	IEA
GO:0005096	Function	GTPase activator activity	TAS	10747990
GO:0005515	Function	Protein binding	IPI	21784977
GO:0005516	Function	Calmodulin binding	TAS	10747990
GO:0005737	Component	Cytoplasm	IDA	10791963
GO:0005886	Component	Plasma membrane	TAS
GO:0007186	Process	G protein-coupled receptor signaling pathway	IEA
GO:0007186	Process	G protein-coupled receptor signaling pathway	ISS
GO:0007186	Process	G protein-coupled receptor signaling pathway	TAS
GO:0007601	Process	Visual perception	TAS	9469939
GO:0008277	Process	Regulation of G protein-coupled receptor signaling pathway	TAS	10747990
GO:0009968	Process	Negative regulation of signal transduction	IEA
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	ISS
GO:0043547	Process	Positive regulation of GTPase activity	IDA	18434541

Other IDs

• MIM: 602514
• HGNC: 9997
• e!Ensembl: ENSG00000143333

Protein

• UniProt ID: O15492
• Protein name: Regulator of G-protein signaling 16 (RGS16) (A28-RGS14P) (Retinal-specific RGS) (RGS-r) (hRGS-r) (Retinally abundant regulator of G-protein signaling)
• Protein function: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:11602604, PubMed:18434541). Play
• PDB: 2BT2, 2IK8
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00615	RGS	65 → 180	Regulator of G protein signaling domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Abundantly expressed in retina with lower levels of expression in most other tissues.
• Sequence:

  MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVL
  GWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEE
  FICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDL
  AAQASAASATLSSCSLDEPSHT

• Sequence length: 202

Pathways

Reactome:

G alpha (q) signalling events
G alpha (i) signalling events
G alpha (z) signalling events

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
INSOMNIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Bicuspid Aortic Valve Disease	Bicuspid aortic valve	Pubtator	36071494	Associate	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	19509421	Inhibit	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	26823172	Associate	★☆☆☆☆ Found in Text Mining only
Chondrosarcoma	Chondrosarcoma	Pubtator	26013170	Associate	★☆☆☆☆ Found in Text Mining only
Colitis Ulcerative	Ulcerative colitis	Pubtator	35830366	Stimulate	★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	19760045		★☆☆☆☆ Found in Text Mining only
Dermatitis Contact	Contact dermatitis	Pubtator	33318199	Associate	★☆☆☆☆ Found in Text Mining only
Familial lichen amyloidosis	Lichen amyloidosis	BEFREE	27635024		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	32319728	Associate	★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	20571966	Inhibit	★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of gastrointestinal tract	Malignant gastrointestinal tract tumors	BEFREE	19760045		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	20571966		★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	BEFREE	18521847		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	18521847		★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	16012519		★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	33845140	Associate	★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	20571966		★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	20571966	Associate	★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	36686485	Associate	★☆☆☆☆ Found in Text Mining only