RCN1 (reticulocalbin 1)

Gene

• Entrez ID: 5954
• Gene name: Reticulocalbin 1
• Gene symbol: RCN1
• Synonyms (NCBI Gene): HEL-S-84, PIG20, RCAL, RCN
• Chromosome: 11
• Chromosome location: 11p13
• Summary: Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT025453	hsa-miR-34a-5p	Proteomics	21566225
MIRT025453	hsa-miR-34a-5p	Proteomics	21566225
MIRT1298338	hsa-miR-1245	CLIP-seq
MIRT1298339	hsa-miR-1297	CLIP-seq
MIRT1298340	hsa-miR-1305	CLIP-seq
MIRT1298341	hsa-miR-2052	CLIP-seq
MIRT1298342	hsa-miR-26a	CLIP-seq
MIRT1298343	hsa-miR-26b	CLIP-seq
MIRT1298344	hsa-miR-2964a-5p	CLIP-seq
MIRT1298345	hsa-miR-3119	CLIP-seq
MIRT1298346	hsa-miR-3158-3p	CLIP-seq
MIRT1298347	hsa-miR-3591-3p	CLIP-seq
MIRT1298348	hsa-miR-3611	CLIP-seq
MIRT1298349	hsa-miR-3676	CLIP-seq
MIRT1298350	hsa-miR-375	CLIP-seq
MIRT1298351	hsa-miR-4465	CLIP-seq
MIRT1298352	hsa-miR-4677-3p	CLIP-seq
MIRT1298353	hsa-miR-4679	CLIP-seq
MIRT1298354	hsa-miR-4724-5p	CLIP-seq
MIRT1298355	hsa-miR-4766-5p	CLIP-seq
MIRT1298356	hsa-miR-498	CLIP-seq
MIRT1298357	hsa-miR-5096	CLIP-seq
MIRT1298358	hsa-miR-513c	CLIP-seq
MIRT1298359	hsa-miR-514b-5p	CLIP-seq
MIRT1298360	hsa-miR-539	CLIP-seq
MIRT1298361	hsa-miR-548u	CLIP-seq
MIRT1298362	hsa-miR-550b	CLIP-seq
MIRT1298363	hsa-miR-561	CLIP-seq
MIRT1553029	hsa-miR-105	CLIP-seq
MIRT1553030	hsa-miR-181a	CLIP-seq
MIRT1553031	hsa-miR-181b	CLIP-seq
MIRT1553032	hsa-miR-181c	CLIP-seq
MIRT1553033	hsa-miR-181d	CLIP-seq
MIRT1553034	hsa-miR-23a	CLIP-seq
MIRT1553035	hsa-miR-23b	CLIP-seq
MIRT1553036	hsa-miR-23c	CLIP-seq
MIRT1553037	hsa-miR-3162-3p	CLIP-seq
MIRT1553038	hsa-miR-3660	CLIP-seq
MIRT1553039	hsa-miR-3671	CLIP-seq
MIRT1553040	hsa-miR-4262	CLIP-seq
MIRT1553041	hsa-miR-4446-5p	CLIP-seq
MIRT1553042	hsa-miR-4526	CLIP-seq
MIRT1553043	hsa-miR-4755-5p	CLIP-seq
MIRT1298357	hsa-miR-5096	CLIP-seq
MIRT1553044	hsa-miR-526b	CLIP-seq
MIRT1553045	hsa-miR-578	CLIP-seq
MIRT1553046	hsa-miR-607	CLIP-seq
MIRT1553047	hsa-miR-654-3p	CLIP-seq
MIRT1553048	hsa-miR-759	CLIP-seq
MIRT1553029	hsa-miR-105	CLIP-seq
MIRT1298339	hsa-miR-1297	CLIP-seq
MIRT1553030	hsa-miR-181a	CLIP-seq
MIRT1553031	hsa-miR-181b	CLIP-seq
MIRT1553032	hsa-miR-181c	CLIP-seq
MIRT1553033	hsa-miR-181d	CLIP-seq
MIRT1298342	hsa-miR-26a	CLIP-seq
MIRT1298343	hsa-miR-26b	CLIP-seq
MIRT2088755	hsa-miR-3127-3p	CLIP-seq
MIRT2088756	hsa-miR-3168	CLIP-seq
MIRT2088757	hsa-miR-3621	CLIP-seq
MIRT2088758	hsa-miR-3656	CLIP-seq
MIRT1553038	hsa-miR-3660	CLIP-seq
MIRT1553039	hsa-miR-3671	CLIP-seq
MIRT1553040	hsa-miR-4262	CLIP-seq
MIRT2088759	hsa-miR-4320	CLIP-seq
MIRT2088760	hsa-miR-4420	CLIP-seq
MIRT2088761	hsa-miR-4440	CLIP-seq
MIRT1298351	hsa-miR-4465	CLIP-seq
MIRT2088762	hsa-miR-4477a	CLIP-seq
MIRT1553042	hsa-miR-4526	CLIP-seq
MIRT2088763	hsa-miR-4527	CLIP-seq
MIRT2088764	hsa-miR-4734	CLIP-seq
MIRT2088765	hsa-miR-572	CLIP-seq
MIRT1553046	hsa-miR-607	CLIP-seq
MIRT2088766	hsa-miR-640	CLIP-seq
MIRT1553047	hsa-miR-654-3p	CLIP-seq
MIRT2313645	hsa-miR-1243	CLIP-seq
MIRT1298338	hsa-miR-1245	CLIP-seq
MIRT2313646	hsa-miR-1246	CLIP-seq
MIRT2313647	hsa-miR-1290	CLIP-seq
MIRT1298339	hsa-miR-1297	CLIP-seq
MIRT2313648	hsa-miR-145	CLIP-seq
MIRT2313649	hsa-miR-186	CLIP-seq
MIRT2313650	hsa-miR-1972	CLIP-seq
MIRT2313651	hsa-miR-200b	CLIP-seq
MIRT2313652	hsa-miR-200c	CLIP-seq
MIRT1298341	hsa-miR-2052	CLIP-seq
MIRT2313653	hsa-miR-2113	CLIP-seq
MIRT2313654	hsa-miR-224	CLIP-seq
MIRT1298342	hsa-miR-26a	CLIP-seq
MIRT1298343	hsa-miR-26b	CLIP-seq
MIRT2088755	hsa-miR-3127-3p	CLIP-seq
MIRT2313655	hsa-miR-3140-3p	CLIP-seq
MIRT2313656	hsa-miR-3144-3p	CLIP-seq
MIRT2313657	hsa-miR-3167	CLIP-seq
MIRT2313658	hsa-miR-3180-5p	CLIP-seq
MIRT2313659	hsa-miR-3200-5p	CLIP-seq
MIRT2313660	hsa-miR-337-3p	CLIP-seq
MIRT2313661	hsa-miR-33a	CLIP-seq
MIRT2313662	hsa-miR-33b	CLIP-seq
MIRT2313663	hsa-miR-3613-5p	CLIP-seq
MIRT2313664	hsa-miR-3654	CLIP-seq
MIRT1298349	hsa-miR-3676	CLIP-seq
MIRT2313665	hsa-miR-3915	CLIP-seq
MIRT2313666	hsa-miR-3928	CLIP-seq
MIRT2313667	hsa-miR-4265	CLIP-seq
MIRT2313668	hsa-miR-4276	CLIP-seq
MIRT2313669	hsa-miR-429	CLIP-seq
MIRT2313670	hsa-miR-4296	CLIP-seq
MIRT2313671	hsa-miR-4322	CLIP-seq
MIRT2088760	hsa-miR-4420	CLIP-seq
MIRT1298351	hsa-miR-4465	CLIP-seq
MIRT2313672	hsa-miR-4469	CLIP-seq
MIRT2313673	hsa-miR-450b-3p	CLIP-seq
MIRT2313674	hsa-miR-4642	CLIP-seq
MIRT2313675	hsa-miR-4648	CLIP-seq
MIRT2313676	hsa-miR-4650-5p	CLIP-seq
MIRT2313677	hsa-miR-4654	CLIP-seq
MIRT2313678	hsa-miR-4699-3p	CLIP-seq
MIRT2313679	hsa-miR-4712-5p	CLIP-seq
MIRT2313680	hsa-miR-4713-3p	CLIP-seq
MIRT2313681	hsa-miR-4769-5p	CLIP-seq
MIRT2313682	hsa-miR-4772-5p	CLIP-seq
MIRT2313683	hsa-miR-4777-3p	CLIP-seq
MIRT1298357	hsa-miR-5096	CLIP-seq
MIRT2313684	hsa-miR-576-5p	CLIP-seq
MIRT2313685	hsa-miR-586	CLIP-seq
MIRT1553046	hsa-miR-607	CLIP-seq
MIRT2313686	hsa-miR-630	CLIP-seq
MIRT2313687	hsa-miR-638	CLIP-seq
MIRT2313688	hsa-miR-769-3p	CLIP-seq
MIRT2313689	hsa-miR-770-5p	CLIP-seq
MIRT2313690	hsa-miR-876-5p	CLIP-seq
MIRT2313673	hsa-miR-450b-3p	CLIP-seq
MIRT2313680	hsa-miR-4713-3p	CLIP-seq
MIRT2313687	hsa-miR-638	CLIP-seq
MIRT2313688	hsa-miR-769-3p	CLIP-seq
MIRT1553030	hsa-miR-181a	CLIP-seq
MIRT1553031	hsa-miR-181b	CLIP-seq
MIRT1553032	hsa-miR-181c	CLIP-seq
MIRT1553033	hsa-miR-181d	CLIP-seq
MIRT2439882	hsa-miR-1910	CLIP-seq
MIRT2439883	hsa-miR-2355-3p	CLIP-seq
MIRT1553034	hsa-miR-23a	CLIP-seq
MIRT1553035	hsa-miR-23b	CLIP-seq
MIRT1553036	hsa-miR-23c	CLIP-seq
MIRT2313655	hsa-miR-3140-3p	CLIP-seq
MIRT1553037	hsa-miR-3162-3p	CLIP-seq
MIRT2439884	hsa-miR-320e	CLIP-seq
MIRT2439885	hsa-miR-3909	CLIP-seq
MIRT1553040	hsa-miR-4262	CLIP-seq
MIRT1553041	hsa-miR-4446-5p	CLIP-seq
MIRT2088762	hsa-miR-4477a	CLIP-seq
MIRT2439886	hsa-miR-455-3p	CLIP-seq
MIRT1553043	hsa-miR-4755-5p	CLIP-seq
MIRT2439887	hsa-miR-4799-5p	CLIP-seq
MIRT1298357	hsa-miR-5096	CLIP-seq
MIRT1553044	hsa-miR-526b	CLIP-seq
MIRT1553045	hsa-miR-578	CLIP-seq
MIRT2439888	hsa-miR-633	CLIP-seq
MIRT2439889	hsa-miR-676	CLIP-seq
MIRT1553048	hsa-miR-759	CLIP-seq
MIRT1553030	hsa-miR-181a	CLIP-seq
MIRT1553031	hsa-miR-181b	CLIP-seq
MIRT1553032	hsa-miR-181c	CLIP-seq
MIRT1553033	hsa-miR-181d	CLIP-seq
MIRT1553037	hsa-miR-3162-3p	CLIP-seq
MIRT1553040	hsa-miR-4262	CLIP-seq
MIRT1553041	hsa-miR-4446-5p	CLIP-seq
MIRT1553043	hsa-miR-4755-5p	CLIP-seq
MIRT2439887	hsa-miR-4799-5p	CLIP-seq
MIRT2457986	hsa-miR-1208	CLIP-seq
MIRT2457987	hsa-miR-4286	CLIP-seq
MIRT2313673	hsa-miR-450b-3p	CLIP-seq
MIRT2457988	hsa-miR-452	CLIP-seq
MIRT2457989	hsa-miR-4676-3p	CLIP-seq
MIRT2313680	hsa-miR-4713-3p	CLIP-seq
MIRT2313687	hsa-miR-638	CLIP-seq
MIRT2313688	hsa-miR-769-3p	CLIP-seq
MIRT2610248	hsa-let-7a	CLIP-seq
MIRT2610249	hsa-let-7b	CLIP-seq
MIRT2610250	hsa-let-7c	CLIP-seq
MIRT2610251	hsa-let-7d	CLIP-seq
MIRT2610252	hsa-let-7e	CLIP-seq
MIRT2610253	hsa-let-7f	CLIP-seq
MIRT2610254	hsa-let-7g	CLIP-seq
MIRT2610255	hsa-let-7i	CLIP-seq
MIRT2610256	hsa-miR-101	CLIP-seq
MIRT2610257	hsa-miR-1237	CLIP-seq
MIRT2313645	hsa-miR-1243	CLIP-seq
MIRT1298338	hsa-miR-1245	CLIP-seq
MIRT2313646	hsa-miR-1246	CLIP-seq
MIRT2313647	hsa-miR-1290	CLIP-seq
MIRT2610258	hsa-miR-132	CLIP-seq
MIRT2610259	hsa-miR-142-5p	CLIP-seq
MIRT2610260	hsa-miR-144	CLIP-seq
MIRT2313648	hsa-miR-145	CLIP-seq
MIRT2610261	hsa-miR-151-3p	CLIP-seq
MIRT1553030	hsa-miR-181a	CLIP-seq
MIRT1553031	hsa-miR-181b	CLIP-seq
MIRT1553032	hsa-miR-181c	CLIP-seq
MIRT1553033	hsa-miR-181d	CLIP-seq
MIRT2313649	hsa-miR-186	CLIP-seq
MIRT2313651	hsa-miR-200b	CLIP-seq
MIRT2313652	hsa-miR-200c	CLIP-seq
MIRT2610262	hsa-miR-202	CLIP-seq
MIRT2313653	hsa-miR-2113	CLIP-seq
MIRT2610263	hsa-miR-212	CLIP-seq
MIRT1553034	hsa-miR-23a	CLIP-seq
MIRT1553035	hsa-miR-23b	CLIP-seq
MIRT1553036	hsa-miR-23c	CLIP-seq
MIRT1298344	hsa-miR-2964a-5p	CLIP-seq
MIRT2088755	hsa-miR-3127-3p	CLIP-seq
MIRT2313655	hsa-miR-3140-3p	CLIP-seq
MIRT2313656	hsa-miR-3144-3p	CLIP-seq
MIRT2610264	hsa-miR-3148	CLIP-seq
MIRT1553037	hsa-miR-3162-3p	CLIP-seq
MIRT2610265	hsa-miR-3163	CLIP-seq
MIRT2313657	hsa-miR-3167	CLIP-seq
MIRT2313658	hsa-miR-3180-5p	CLIP-seq
MIRT2610266	hsa-miR-3185	CLIP-seq
MIRT2313659	hsa-miR-3200-5p	CLIP-seq
MIRT2610267	hsa-miR-340	CLIP-seq
MIRT2610268	hsa-miR-3617	CLIP-seq
MIRT2313664	hsa-miR-3654	CLIP-seq
MIRT2610269	hsa-miR-3679-3p	CLIP-seq
MIRT2610270	hsa-miR-3688-5p	CLIP-seq
MIRT2610271	hsa-miR-3689d	CLIP-seq
MIRT1553040	hsa-miR-4262	CLIP-seq
MIRT2313667	hsa-miR-4265	CLIP-seq
MIRT2610272	hsa-miR-4273	CLIP-seq
MIRT2313669	hsa-miR-429	CLIP-seq
MIRT2313670	hsa-miR-4296	CLIP-seq
MIRT2610273	hsa-miR-4318	CLIP-seq
MIRT2313671	hsa-miR-4322	CLIP-seq
MIRT1553041	hsa-miR-4446-5p	CLIP-seq
MIRT2610274	hsa-miR-4458	CLIP-seq
MIRT2313672	hsa-miR-4469	CLIP-seq
MIRT2610275	hsa-miR-4470	CLIP-seq
MIRT2610276	hsa-miR-448	CLIP-seq
MIRT2610277	hsa-miR-4490	CLIP-seq
MIRT2610278	hsa-miR-4500	CLIP-seq
MIRT2610279	hsa-miR-4524	CLIP-seq
MIRT2313675	hsa-miR-4648	CLIP-seq
MIRT2610280	hsa-miR-4649-3p	CLIP-seq
MIRT2313677	hsa-miR-4654	CLIP-seq
MIRT2610281	hsa-miR-4677-5p	CLIP-seq
MIRT2610282	hsa-miR-4693-5p	CLIP-seq
MIRT2313678	hsa-miR-4699-3p	CLIP-seq
MIRT2313679	hsa-miR-4712-5p	CLIP-seq
MIRT1553043	hsa-miR-4755-5p	CLIP-seq
MIRT1298355	hsa-miR-4766-5p	CLIP-seq
MIRT2313681	hsa-miR-4769-5p	CLIP-seq
MIRT2610283	hsa-miR-4774-5p	CLIP-seq
MIRT2610284	hsa-miR-4790-5p	CLIP-seq
MIRT2439887	hsa-miR-4799-5p	CLIP-seq
MIRT2610285	hsa-miR-4802-3p	CLIP-seq
MIRT2610286	hsa-miR-4802-5p	CLIP-seq
MIRT2610287	hsa-miR-490-5p	CLIP-seq
MIRT2610288	hsa-miR-495	CLIP-seq
MIRT1298357	hsa-miR-5096	CLIP-seq
MIRT1553044	hsa-miR-526b	CLIP-seq
MIRT2610289	hsa-miR-548c-3p	CLIP-seq
MIRT1298361	hsa-miR-548u	CLIP-seq
MIRT1553045	hsa-miR-578	CLIP-seq
MIRT2610290	hsa-miR-582-5p	CLIP-seq
MIRT2439888	hsa-miR-633	CLIP-seq
MIRT2610291	hsa-miR-641	CLIP-seq
MIRT1553048	hsa-miR-759	CLIP-seq
MIRT2313689	hsa-miR-770-5p	CLIP-seq
MIRT2610292	hsa-miR-875-3p	CLIP-seq
MIRT2313690	hsa-miR-876-5p	CLIP-seq
MIRT2610293	hsa-miR-892a	CLIP-seq
MIRT2610294	hsa-miR-98	CLIP-seq
MIRT2610248	hsa-let-7a	CLIP-seq
MIRT2610249	hsa-let-7b	CLIP-seq
MIRT2610250	hsa-let-7c	CLIP-seq
MIRT2610251	hsa-let-7d	CLIP-seq
MIRT2610252	hsa-let-7e	CLIP-seq
MIRT2610253	hsa-let-7f	CLIP-seq
MIRT2610254	hsa-let-7g	CLIP-seq
MIRT2610255	hsa-let-7i	CLIP-seq
MIRT2610256	hsa-miR-101	CLIP-seq
MIRT2313645	hsa-miR-1243	CLIP-seq
MIRT1298338	hsa-miR-1245	CLIP-seq
MIRT2313646	hsa-miR-1246	CLIP-seq
MIRT2313647	hsa-miR-1290	CLIP-seq
MIRT2610258	hsa-miR-132	CLIP-seq
MIRT2610259	hsa-miR-142-5p	CLIP-seq
MIRT2610260	hsa-miR-144	CLIP-seq
MIRT2313648	hsa-miR-145	CLIP-seq
MIRT2610261	hsa-miR-151-3p	CLIP-seq
MIRT1553030	hsa-miR-181a	CLIP-seq
MIRT1553031	hsa-miR-181b	CLIP-seq
MIRT1553032	hsa-miR-181c	CLIP-seq
MIRT1553033	hsa-miR-181d	CLIP-seq
MIRT2313649	hsa-miR-186	CLIP-seq
MIRT2313651	hsa-miR-200b	CLIP-seq
MIRT2313652	hsa-miR-200c	CLIP-seq
MIRT2610262	hsa-miR-202	CLIP-seq
MIRT2313653	hsa-miR-2113	CLIP-seq
MIRT2610263	hsa-miR-212	CLIP-seq
MIRT1553034	hsa-miR-23a	CLIP-seq
MIRT1553035	hsa-miR-23b	CLIP-seq
MIRT1553036	hsa-miR-23c	CLIP-seq
MIRT1298344	hsa-miR-2964a-5p	CLIP-seq
MIRT2088755	hsa-miR-3127-3p	CLIP-seq
MIRT2313655	hsa-miR-3140-3p	CLIP-seq
MIRT2313656	hsa-miR-3144-3p	CLIP-seq
MIRT2610264	hsa-miR-3148	CLIP-seq
MIRT1553037	hsa-miR-3162-3p	CLIP-seq
MIRT2610265	hsa-miR-3163	CLIP-seq
MIRT2313657	hsa-miR-3167	CLIP-seq
MIRT2313658	hsa-miR-3180-5p	CLIP-seq
MIRT2313659	hsa-miR-3200-5p	CLIP-seq
MIRT2610267	hsa-miR-340	CLIP-seq
MIRT2610268	hsa-miR-3617	CLIP-seq
MIRT2313664	hsa-miR-3654	CLIP-seq
MIRT2610269	hsa-miR-3679-3p	CLIP-seq
MIRT2610270	hsa-miR-3688-5p	CLIP-seq
MIRT2313665	hsa-miR-3915	CLIP-seq
MIRT2313666	hsa-miR-3928	CLIP-seq
MIRT1553040	hsa-miR-4262	CLIP-seq
MIRT2313667	hsa-miR-4265	CLIP-seq
MIRT2610272	hsa-miR-4273	CLIP-seq
MIRT2313668	hsa-miR-4276	CLIP-seq
MIRT2313669	hsa-miR-429	CLIP-seq
MIRT2313670	hsa-miR-4296	CLIP-seq
MIRT2610273	hsa-miR-4318	CLIP-seq
MIRT2313671	hsa-miR-4322	CLIP-seq
MIRT2088760	hsa-miR-4420	CLIP-seq
MIRT1553041	hsa-miR-4446-5p	CLIP-seq
MIRT2610274	hsa-miR-4458	CLIP-seq
MIRT2610275	hsa-miR-4470	CLIP-seq
MIRT2610276	hsa-miR-448	CLIP-seq
MIRT2610278	hsa-miR-4500	CLIP-seq
MIRT2313673	hsa-miR-450b-3p	CLIP-seq
MIRT2610279	hsa-miR-4524	CLIP-seq
MIRT2313675	hsa-miR-4648	CLIP-seq
MIRT2610280	hsa-miR-4649-3p	CLIP-seq
MIRT2313677	hsa-miR-4654	CLIP-seq
MIRT2610281	hsa-miR-4677-5p	CLIP-seq
MIRT2610282	hsa-miR-4693-5p	CLIP-seq
MIRT2313678	hsa-miR-4699-3p	CLIP-seq
MIRT2313679	hsa-miR-4712-5p	CLIP-seq
MIRT2313680	hsa-miR-4713-3p	CLIP-seq
MIRT1553043	hsa-miR-4755-5p	CLIP-seq
MIRT1298355	hsa-miR-4766-5p	CLIP-seq
MIRT2313681	hsa-miR-4769-5p	CLIP-seq
MIRT2610284	hsa-miR-4790-5p	CLIP-seq
MIRT2439887	hsa-miR-4799-5p	CLIP-seq
MIRT2610285	hsa-miR-4802-3p	CLIP-seq
MIRT2610287	hsa-miR-490-5p	CLIP-seq
MIRT2610288	hsa-miR-495	CLIP-seq
MIRT1298357	hsa-miR-5096	CLIP-seq
MIRT1553044	hsa-miR-526b	CLIP-seq
MIRT1298361	hsa-miR-548u	CLIP-seq
MIRT2313684	hsa-miR-576-5p	CLIP-seq
MIRT1553045	hsa-miR-578	CLIP-seq
MIRT2610290	hsa-miR-582-5p	CLIP-seq
MIRT2439888	hsa-miR-633	CLIP-seq
MIRT2313687	hsa-miR-638	CLIP-seq
MIRT2610291	hsa-miR-641	CLIP-seq
MIRT1553048	hsa-miR-759	CLIP-seq
MIRT2313688	hsa-miR-769-3p	CLIP-seq
MIRT2313689	hsa-miR-770-5p	CLIP-seq
MIRT2610292	hsa-miR-875-3p	CLIP-seq
MIRT2313690	hsa-miR-876-5p	CLIP-seq
MIRT2610293	hsa-miR-892a	CLIP-seq
MIRT2610294	hsa-miR-98	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001701	Process	In utero embryonic development	IEA
GO:0005509	Function	Calcium ion binding	IBA
GO:0005509	Function	Calcium ion binding	IEA
GO:0005509	Function	Calcium ion binding	TAS	8416973
GO:0005515	Function	Protein binding	IPI	16713569, 32296183, 32814053, 36217030
GO:0005783	Component	Endoplasmic reticulum	IBA
GO:0005783	Component	Endoplasmic reticulum	IDA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005788	Component	Endoplasmic reticulum lumen	IEA
GO:0005788	Component	Endoplasmic reticulum lumen	TAS	8416973
GO:0043010	Process	Camera-type eye development	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 602735
• HGNC: 9934
• e!Ensembl: ENSG00000049449

Protein

• UniProt ID: Q15293
• Protein name: Reticulocalbin-1
• Protein function: May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF13202	EF-hand_5	208 → 233	EF hand	Domain
  PF13202	EF-hand_5	251 → 274	EF hand	Domain

• Sequence:

  MARGGRGRRLGLALGLLLALVLAPRVLRAKPTVRKERVVRPDSELGERPPEDNQSFQYDH
  EAFLGKEDSKTFDQLTPDESKERLGKIVDRIDNDGDGFVTTEELKTWIKRVQKRYIFDNV
  AKVWKDYDRDKDDKISWEEYKQATYGYYLGNPAEFHDSSDHHTFKKMLPRDERRFKAADL
  NGDLTATREEFTAFLHPEEFEHMKEIVVLETLEDIDKNGDGFVDQDEYIADMFSHEENGP
  EPDWVLSEREQFNEFRDLNKDGKLDKDEIRHWILPQDYDHAQAEARHLVYESDKNKDEKL
  TKEEILENWNMFVGSQATNYGEDLTKNHDEL

• Sequence length: 331

Pathways

Reactome:

Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
CARCINOMA	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLOR VISION DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LIVER CIRRHOSIS, EXPERIMENTAL	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Anaplastic carcinoma	Anaplastic Carcinoma	CTD_human_DG	16316942		★☆☆☆☆ Found in Text Mining only
Aniridia	Aniridia	Pubtator	21364908	Associate	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	27572108	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	CTD_human_DG	16316942		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	23916412	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma, Spindle-Cell	Carcinoma	CTD_human_DG	16316942		★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	UNIPROT_DG			★☆☆☆☆ Found in Text Mining only
Dementia	Dementia	BEFREE	31556943		★☆☆☆☆ Found in Text Mining only
Down Syndrome	Down Syndrome	BEFREE	28849527		★☆☆☆☆ Found in Text Mining only
Esophageal Squamous Cell Carcinoma	Esophageal squamous cell carcinoma	Pubtator	40244296	Associate	★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	35436915	Associate	★☆☆☆☆ Found in Text Mining only
Hereditary Breast and Ovarian Cancer Syndrome	Hereditary breast and ovarian cancer syndrome	Pubtator	27572108	Associate	★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of kidney	Kidney Cancer	BEFREE	14871811		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	18561328, 29453900		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	29453900		★☆☆☆☆ Found in Text Mining only
Nasopharyngeal Carcinoma	Nasopharyngeal carcinoma	Pubtator	31770211	Associate	★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	27790916		★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	Pubtator	21573212	Associate	★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	30172915		★☆☆☆☆ Found in Text Mining only
Osteopenia	Osteopenia	BEFREE	31032961		★☆☆☆☆ Found in Text Mining only
Periodontitis	Periodontitis	BEFREE	31032961		★☆☆☆☆ Found in Text Mining only
Presenile dementia	Senile Dementia	BEFREE	31556943		★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	18561328, 29453900		★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	18561328	Associate	★☆☆☆☆ Found in Text Mining only
Renal carcinoma	Renal Carcinoma	BEFREE	14871811		★☆☆☆☆ Found in Text Mining only
Scleroderma Systemic	Systemic sclerosis	Pubtator	20724591	Associate	★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	32871760	Stimulate	★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	38057406	Associate	★☆☆☆☆ Found in Text Mining only
Undifferentiated carcinoma	Carcinoma	CTD_human_DG	16316942		★☆☆☆☆ Found in Text Mining only
Vision Disorders	Visual disorder	Pubtator	21364908	Associate	★☆☆☆☆ Found in Text Mining only