RBBP6 (RB binding protein 6, ubiquitin ligase)

Gene

• Entrez ID: 5930
• Gene name: RB binding protein 6, ubiquitin ligase
• Gene symbol: RBBP6
• Synonyms (NCBI Gene): MY038, P2P-R, PACT, RBQ-1, SNAMA
• Chromosome: 16
• Chromosome location: 16p12.1
• Summary: The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a p

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT052305	hsa-let-7b-5p	CLASH	23622248
MIRT045398	hsa-miR-149-5p	CLASH	23622248
MIRT035852	hsa-miR-1254	CLASH	23622248
MIRT250406	hsa-miR-193a-5p	PAR-CLIP	20371350
MIRT501409	hsa-miR-103a-3p	PAR-CLIP	20371350
MIRT501408	hsa-miR-107	PAR-CLIP	20371350
MIRT501407	hsa-miR-373-3p	PAR-CLIP	20371350
MIRT501406	hsa-miR-520b	PAR-CLIP	20371350
MIRT501405	hsa-miR-302a-3p	PAR-CLIP	20371350
MIRT501404	hsa-miR-302d-3p	PAR-CLIP	20371350
MIRT501403	hsa-miR-302e	PAR-CLIP	20371350
MIRT501402	hsa-miR-520c-3p	PAR-CLIP	20371350
MIRT501401	hsa-miR-302c-3p	PAR-CLIP	20371350
MIRT501400	hsa-miR-302b-3p	PAR-CLIP	20371350
MIRT501399	hsa-miR-520d-3p	PAR-CLIP	20371350
MIRT501398	hsa-miR-520e	PAR-CLIP	20371350
MIRT501397	hsa-miR-372-3p	PAR-CLIP	20371350
MIRT501396	hsa-miR-520a-3p	PAR-CLIP	20371350
MIRT194917	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT194903	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT194904	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT194909	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT194907	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT194910	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT194906	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT194913	hsa-miR-519a-3p	PAR-CLIP	20371350
MIRT194912	hsa-miR-519b-3p	PAR-CLIP	20371350
MIRT194911	hsa-miR-519c-3p	PAR-CLIP	20371350
MIRT194914	hsa-miR-3942-5p	PAR-CLIP	20371350
MIRT194916	hsa-miR-4703-5p	PAR-CLIP	20371350
MIRT250408	hsa-miR-1182	PAR-CLIP	20371350
MIRT194905	hsa-miR-16-2-3p	PAR-CLIP	20371350
MIRT194908	hsa-miR-195-3p	PAR-CLIP	20371350
MIRT194915	hsa-miR-3944-5p	PAR-CLIP	20371350
MIRT194918	hsa-miR-7856-5p	PAR-CLIP	20371350
MIRT250406	hsa-miR-193a-5p	PAR-CLIP	21572407
MIRT501409	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT501408	hsa-miR-107	PAR-CLIP	21572407
MIRT501407	hsa-miR-373-3p	PAR-CLIP	21572407
MIRT501406	hsa-miR-520b	PAR-CLIP	21572407
MIRT501405	hsa-miR-302a-3p	PAR-CLIP	21572407
MIRT501404	hsa-miR-302d-3p	PAR-CLIP	21572407
MIRT501403	hsa-miR-302e	PAR-CLIP	21572407
MIRT501402	hsa-miR-520c-3p	PAR-CLIP	21572407
MIRT501401	hsa-miR-302c-3p	PAR-CLIP	21572407
MIRT501400	hsa-miR-302b-3p	PAR-CLIP	21572407
MIRT501399	hsa-miR-520d-3p	PAR-CLIP	21572407
MIRT501398	hsa-miR-520e	PAR-CLIP	21572407
MIRT501397	hsa-miR-372-3p	PAR-CLIP	21572407
MIRT501396	hsa-miR-520a-3p	PAR-CLIP	21572407
MIRT194917	hsa-miR-6838-5p	PAR-CLIP	21572407
MIRT194903	hsa-miR-15a-5p	PAR-CLIP	21572407
MIRT194904	hsa-miR-16-5p	PAR-CLIP	21572407
MIRT194909	hsa-miR-424-5p	PAR-CLIP	21572407
MIRT194907	hsa-miR-195-5p	PAR-CLIP	21572407
MIRT194910	hsa-miR-497-5p	PAR-CLIP	21572407
MIRT194906	hsa-miR-15b-5p	PAR-CLIP	21572407
MIRT194913	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT194912	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT194911	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT194914	hsa-miR-3942-5p	PAR-CLIP	21572407
MIRT194916	hsa-miR-4703-5p	PAR-CLIP	21572407
MIRT250408	hsa-miR-1182	PAR-CLIP	21572407
MIRT194905	hsa-miR-16-2-3p	PAR-CLIP	21572407
MIRT194908	hsa-miR-195-3p	PAR-CLIP	21572407
MIRT194915	hsa-miR-3944-5p	PAR-CLIP	21572407
MIRT194918	hsa-miR-7856-5p	PAR-CLIP	21572407
MIRT142311	hsa-miR-548c-3p	PAR-CLIP	21572407
MIRT115493	hsa-miR-5692a	PAR-CLIP	21572407
MIRT142316	hsa-miR-3129-3p	PAR-CLIP	21572407
MIRT142329	hsa-miR-5583-5p	PAR-CLIP	21572407
MIRT115491	hsa-miR-4747-3p	PAR-CLIP	21572407
MIRT115492	hsa-miR-1295b-3p	PAR-CLIP	21572407
MIRT142335	hsa-miR-6793-3p	PAR-CLIP	21572407
MIRT115489	hsa-miR-323a-5p	PAR-CLIP	21572407
MIRT115490	hsa-miR-876-3p	PAR-CLIP	21572407
MIRT250406	hsa-miR-193a-5p	PAR-CLIP	23446348
MIRT501409	hsa-miR-103a-3p	PAR-CLIP	23446348
MIRT501408	hsa-miR-107	PAR-CLIP	23446348
MIRT501407	hsa-miR-373-3p	PAR-CLIP	23446348
MIRT501406	hsa-miR-520b	PAR-CLIP	23446348
MIRT501405	hsa-miR-302a-3p	PAR-CLIP	23446348
MIRT501404	hsa-miR-302d-3p	PAR-CLIP	23446348
MIRT501403	hsa-miR-302e	PAR-CLIP	23446348
MIRT501402	hsa-miR-520c-3p	PAR-CLIP	23446348
MIRT501401	hsa-miR-302c-3p	PAR-CLIP	23446348
MIRT501400	hsa-miR-302b-3p	PAR-CLIP	23446348
MIRT501399	hsa-miR-520d-3p	PAR-CLIP	23446348
MIRT501398	hsa-miR-520e	PAR-CLIP	23446348
MIRT501397	hsa-miR-372-3p	PAR-CLIP	23446348
MIRT501396	hsa-miR-520a-3p	PAR-CLIP	23446348
MIRT194917	hsa-miR-6838-5p	PAR-CLIP	23446348
MIRT194903	hsa-miR-15a-5p	PAR-CLIP	23446348
MIRT194904	hsa-miR-16-5p	PAR-CLIP	23446348
MIRT194909	hsa-miR-424-5p	PAR-CLIP	23446348
MIRT194907	hsa-miR-195-5p	PAR-CLIP	23446348
MIRT194910	hsa-miR-497-5p	PAR-CLIP	23446348
MIRT194906	hsa-miR-15b-5p	PAR-CLIP	23446348
MIRT194913	hsa-miR-519a-3p	PAR-CLIP	23446348
MIRT194912	hsa-miR-519b-3p	PAR-CLIP	23446348
MIRT194911	hsa-miR-519c-3p	PAR-CLIP	23446348
MIRT194914	hsa-miR-3942-5p	PAR-CLIP	23446348
MIRT194916	hsa-miR-4703-5p	PAR-CLIP	23446348
MIRT250408	hsa-miR-1182	PAR-CLIP	23446348
MIRT194905	hsa-miR-16-2-3p	PAR-CLIP	23446348
MIRT194908	hsa-miR-195-3p	PAR-CLIP	23446348
MIRT194915	hsa-miR-3944-5p	PAR-CLIP	23446348
MIRT194918	hsa-miR-7856-5p	PAR-CLIP	23446348
MIRT501409	hsa-miR-103a-3p	PAR-CLIP	24398324
MIRT501408	hsa-miR-107	PAR-CLIP	24398324
MIRT501407	hsa-miR-373-3p	PAR-CLIP	24398324
MIRT501406	hsa-miR-520b	PAR-CLIP	24398324
MIRT501405	hsa-miR-302a-3p	PAR-CLIP	24398324
MIRT501404	hsa-miR-302d-3p	PAR-CLIP	24398324
MIRT501403	hsa-miR-302e	PAR-CLIP	24398324
MIRT501402	hsa-miR-520c-3p	PAR-CLIP	24398324
MIRT501401	hsa-miR-302c-3p	PAR-CLIP	24398324
MIRT501400	hsa-miR-302b-3p	PAR-CLIP	24398324
MIRT501399	hsa-miR-520d-3p	PAR-CLIP	24398324
MIRT501398	hsa-miR-520e	PAR-CLIP	24398324
MIRT501397	hsa-miR-372-3p	PAR-CLIP	24398324
MIRT501396	hsa-miR-520a-3p	PAR-CLIP	24398324
MIRT194917	hsa-miR-6838-5p	PAR-CLIP	24398324
MIRT194903	hsa-miR-15a-5p	PAR-CLIP	24398324
MIRT194904	hsa-miR-16-5p	PAR-CLIP	24398324
MIRT194909	hsa-miR-424-5p	PAR-CLIP	24398324
MIRT194907	hsa-miR-195-5p	PAR-CLIP	24398324
MIRT194910	hsa-miR-497-5p	PAR-CLIP	24398324
MIRT194906	hsa-miR-15b-5p	PAR-CLIP	24398324
MIRT194913	hsa-miR-519a-3p	PAR-CLIP	24398324
MIRT194912	hsa-miR-519b-3p	PAR-CLIP	24398324
MIRT194911	hsa-miR-519c-3p	PAR-CLIP	24398324
MIRT194914	hsa-miR-3942-5p	PAR-CLIP	24398324
MIRT194916	hsa-miR-4703-5p	PAR-CLIP	24398324
MIRT250408	hsa-miR-1182	PAR-CLIP	24398324
MIRT194905	hsa-miR-16-2-3p	PAR-CLIP	24398324
MIRT194908	hsa-miR-195-3p	PAR-CLIP	24398324
MIRT194915	hsa-miR-3944-5p	PAR-CLIP	24398324
MIRT194918	hsa-miR-7856-5p	PAR-CLIP	24398324
MIRT439811	ebv-miR-BART10-3p	HITS-CLIP	22473208
MIRT439811	ebv-miR-BART10-3p	HITS-CLIP	22473208
MIRT250406	hsa-miR-193a-5p	PAR-CLIP	20371350
MIRT501409	hsa-miR-103a-3p	PAR-CLIP	20371350
MIRT501408	hsa-miR-107	PAR-CLIP	20371350
MIRT501407	hsa-miR-373-3p	PAR-CLIP	20371350
MIRT501406	hsa-miR-520b	PAR-CLIP	20371350
MIRT501405	hsa-miR-302a-3p	PAR-CLIP	20371350
MIRT501404	hsa-miR-302d-3p	PAR-CLIP	20371350
MIRT501403	hsa-miR-302e	PAR-CLIP	20371350
MIRT501402	hsa-miR-520c-3p	PAR-CLIP	20371350
MIRT501401	hsa-miR-302c-3p	PAR-CLIP	20371350
MIRT501400	hsa-miR-302b-3p	PAR-CLIP	20371350
MIRT501399	hsa-miR-520d-3p	PAR-CLIP	20371350
MIRT501398	hsa-miR-520e	PAR-CLIP	20371350
MIRT501397	hsa-miR-372-3p	PAR-CLIP	20371350
MIRT501396	hsa-miR-520a-3p	PAR-CLIP	20371350
MIRT194917	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT194903	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT194904	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT194909	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT194907	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT194910	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT194906	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT194913	hsa-miR-519a-3p	PAR-CLIP	20371350
MIRT194912	hsa-miR-519b-3p	PAR-CLIP	20371350
MIRT194911	hsa-miR-519c-3p	PAR-CLIP	20371350
MIRT194914	hsa-miR-3942-5p	PAR-CLIP	20371350
MIRT194916	hsa-miR-4703-5p	PAR-CLIP	20371350
MIRT250408	hsa-miR-1182	PAR-CLIP	20371350
MIRT194905	hsa-miR-16-2-3p	PAR-CLIP	20371350
MIRT194908	hsa-miR-195-3p	PAR-CLIP	20371350
MIRT194915	hsa-miR-3944-5p	PAR-CLIP	20371350
MIRT194918	hsa-miR-7856-5p	PAR-CLIP	20371350
MIRT250406	hsa-miR-193a-5p	PAR-CLIP	21572407
MIRT501409	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT501408	hsa-miR-107	PAR-CLIP	21572407
MIRT501407	hsa-miR-373-3p	PAR-CLIP	21572407
MIRT501406	hsa-miR-520b	PAR-CLIP	21572407
MIRT501405	hsa-miR-302a-3p	PAR-CLIP	21572407
MIRT501404	hsa-miR-302d-3p	PAR-CLIP	21572407
MIRT501403	hsa-miR-302e	PAR-CLIP	21572407
MIRT501402	hsa-miR-520c-3p	PAR-CLIP	21572407
MIRT501401	hsa-miR-302c-3p	PAR-CLIP	21572407
MIRT501400	hsa-miR-302b-3p	PAR-CLIP	21572407
MIRT501399	hsa-miR-520d-3p	PAR-CLIP	21572407
MIRT501398	hsa-miR-520e	PAR-CLIP	21572407
MIRT501397	hsa-miR-372-3p	PAR-CLIP	21572407
MIRT501396	hsa-miR-520a-3p	PAR-CLIP	21572407
MIRT194917	hsa-miR-6838-5p	PAR-CLIP	21572407
MIRT194903	hsa-miR-15a-5p	PAR-CLIP	21572407
MIRT194904	hsa-miR-16-5p	PAR-CLIP	21572407
MIRT194909	hsa-miR-424-5p	PAR-CLIP	21572407
MIRT194907	hsa-miR-195-5p	PAR-CLIP	21572407
MIRT194910	hsa-miR-497-5p	PAR-CLIP	21572407
MIRT194906	hsa-miR-15b-5p	PAR-CLIP	21572407
MIRT194913	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT194912	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT194911	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT194914	hsa-miR-3942-5p	PAR-CLIP	21572407
MIRT194916	hsa-miR-4703-5p	PAR-CLIP	21572407
MIRT250408	hsa-miR-1182	PAR-CLIP	21572407
MIRT194905	hsa-miR-16-2-3p	PAR-CLIP	21572407
MIRT194908	hsa-miR-195-3p	PAR-CLIP	21572407
MIRT194915	hsa-miR-3944-5p	PAR-CLIP	21572407
MIRT194918	hsa-miR-7856-5p	PAR-CLIP	21572407
MIRT142311	hsa-miR-548c-3p	PAR-CLIP	21572407
MIRT115493	hsa-miR-5692a	PAR-CLIP	21572407
MIRT142316	hsa-miR-3129-3p	PAR-CLIP	21572407
MIRT142329	hsa-miR-5583-5p	PAR-CLIP	21572407
MIRT115491	hsa-miR-4747-3p	PAR-CLIP	21572407
MIRT115492	hsa-miR-1295b-3p	PAR-CLIP	21572407
MIRT142335	hsa-miR-6793-3p	PAR-CLIP	21572407
MIRT115489	hsa-miR-323a-5p	PAR-CLIP	21572407
MIRT115490	hsa-miR-876-3p	PAR-CLIP	21572407
MIRT250406	hsa-miR-193a-5p	PAR-CLIP	23446348
MIRT501409	hsa-miR-103a-3p	PAR-CLIP	23446348
MIRT501408	hsa-miR-107	PAR-CLIP	23446348
MIRT501407	hsa-miR-373-3p	PAR-CLIP	23446348
MIRT501406	hsa-miR-520b	PAR-CLIP	23446348
MIRT501405	hsa-miR-302a-3p	PAR-CLIP	23446348
MIRT501404	hsa-miR-302d-3p	PAR-CLIP	23446348
MIRT501403	hsa-miR-302e	PAR-CLIP	23446348
MIRT501402	hsa-miR-520c-3p	PAR-CLIP	23446348
MIRT501401	hsa-miR-302c-3p	PAR-CLIP	23446348
MIRT501400	hsa-miR-302b-3p	PAR-CLIP	23446348
MIRT501399	hsa-miR-520d-3p	PAR-CLIP	23446348
MIRT501398	hsa-miR-520e	PAR-CLIP	23446348
MIRT501397	hsa-miR-372-3p	PAR-CLIP	23446348
MIRT501396	hsa-miR-520a-3p	PAR-CLIP	23446348
MIRT194917	hsa-miR-6838-5p	PAR-CLIP	23446348
MIRT194903	hsa-miR-15a-5p	PAR-CLIP	23446348
MIRT194904	hsa-miR-16-5p	PAR-CLIP	23446348
MIRT194909	hsa-miR-424-5p	PAR-CLIP	23446348
MIRT194907	hsa-miR-195-5p	PAR-CLIP	23446348
MIRT194910	hsa-miR-497-5p	PAR-CLIP	23446348
MIRT194906	hsa-miR-15b-5p	PAR-CLIP	23446348
MIRT194913	hsa-miR-519a-3p	PAR-CLIP	23446348
MIRT194912	hsa-miR-519b-3p	PAR-CLIP	23446348
MIRT194911	hsa-miR-519c-3p	PAR-CLIP	23446348
MIRT194914	hsa-miR-3942-5p	PAR-CLIP	23446348
MIRT194916	hsa-miR-4703-5p	PAR-CLIP	23446348
MIRT250408	hsa-miR-1182	PAR-CLIP	23446348
MIRT194905	hsa-miR-16-2-3p	PAR-CLIP	23446348
MIRT194908	hsa-miR-195-3p	PAR-CLIP	23446348
MIRT194915	hsa-miR-3944-5p	PAR-CLIP	23446348
MIRT194918	hsa-miR-7856-5p	PAR-CLIP	23446348
MIRT501409	hsa-miR-103a-3p	PAR-CLIP	24398324
MIRT501408	hsa-miR-107	PAR-CLIP	24398324
MIRT501407	hsa-miR-373-3p	PAR-CLIP	24398324
MIRT501406	hsa-miR-520b	PAR-CLIP	24398324
MIRT501405	hsa-miR-302a-3p	PAR-CLIP	24398324
MIRT501404	hsa-miR-302d-3p	PAR-CLIP	24398324
MIRT501403	hsa-miR-302e	PAR-CLIP	24398324
MIRT501402	hsa-miR-520c-3p	PAR-CLIP	24398324
MIRT501401	hsa-miR-302c-3p	PAR-CLIP	24398324
MIRT501400	hsa-miR-302b-3p	PAR-CLIP	24398324
MIRT501399	hsa-miR-520d-3p	PAR-CLIP	24398324
MIRT501398	hsa-miR-520e	PAR-CLIP	24398324
MIRT501397	hsa-miR-372-3p	PAR-CLIP	24398324
MIRT501396	hsa-miR-520a-3p	PAR-CLIP	24398324
MIRT194917	hsa-miR-6838-5p	PAR-CLIP	24398324
MIRT194903	hsa-miR-15a-5p	PAR-CLIP	24398324
MIRT194904	hsa-miR-16-5p	PAR-CLIP	24398324
MIRT194909	hsa-miR-424-5p	PAR-CLIP	24398324
MIRT194907	hsa-miR-195-5p	PAR-CLIP	24398324
MIRT194910	hsa-miR-497-5p	PAR-CLIP	24398324
MIRT194906	hsa-miR-15b-5p	PAR-CLIP	24398324
MIRT194913	hsa-miR-519a-3p	PAR-CLIP	24398324
MIRT194912	hsa-miR-519b-3p	PAR-CLIP	24398324
MIRT194911	hsa-miR-519c-3p	PAR-CLIP	24398324
MIRT194914	hsa-miR-3942-5p	PAR-CLIP	24398324
MIRT194916	hsa-miR-4703-5p	PAR-CLIP	24398324
MIRT250408	hsa-miR-1182	PAR-CLIP	24398324
MIRT194905	hsa-miR-16-2-3p	PAR-CLIP	24398324
MIRT194908	hsa-miR-195-3p	PAR-CLIP	24398324
MIRT194915	hsa-miR-3944-5p	PAR-CLIP	24398324
MIRT194918	hsa-miR-7856-5p	PAR-CLIP	24398324
MIRT1293889	hsa-miR-103a	CLIP-seq
MIRT1293890	hsa-miR-15a	CLIP-seq
MIRT1293891	hsa-miR-15b	CLIP-seq
MIRT1293892	hsa-miR-16	CLIP-seq
MIRT1293893	hsa-miR-195	CLIP-seq
MIRT1293894	hsa-miR-2054	CLIP-seq
MIRT1293895	hsa-miR-216b	CLIP-seq
MIRT1293896	hsa-miR-302a	CLIP-seq
MIRT1293897	hsa-miR-302b	CLIP-seq
MIRT1293898	hsa-miR-302c	CLIP-seq
MIRT1293899	hsa-miR-302d	CLIP-seq
MIRT1293900	hsa-miR-3171	CLIP-seq
MIRT1293901	hsa-miR-3609	CLIP-seq
MIRT1293902	hsa-miR-3613-3p	CLIP-seq
MIRT1293903	hsa-miR-3671	CLIP-seq
MIRT1293904	hsa-miR-372	CLIP-seq
MIRT1293905	hsa-miR-373	CLIP-seq
MIRT1293906	hsa-miR-424	CLIP-seq
MIRT1293907	hsa-miR-4495	CLIP-seq
MIRT1293908	hsa-miR-4502	CLIP-seq
MIRT1293909	hsa-miR-4528	CLIP-seq
MIRT1293910	hsa-miR-4699-3p	CLIP-seq
MIRT1293911	hsa-miR-4716-5p	CLIP-seq
MIRT1293912	hsa-miR-4753-3p	CLIP-seq
MIRT1293913	hsa-miR-497	CLIP-seq
MIRT1293914	hsa-miR-519a	CLIP-seq
MIRT1293915	hsa-miR-548ah	CLIP-seq
MIRT1293916	hsa-miR-548t	CLIP-seq
MIRT1293917	hsa-miR-616	CLIP-seq
MIRT1293918	hsa-miR-624	CLIP-seq
MIRT1293889	hsa-miR-103a	CLIP-seq
MIRT1293890	hsa-miR-15a	CLIP-seq
MIRT1293891	hsa-miR-15b	CLIP-seq
MIRT1293892	hsa-miR-16	CLIP-seq
MIRT1293893	hsa-miR-195	CLIP-seq
MIRT1293894	hsa-miR-2054	CLIP-seq
MIRT1293895	hsa-miR-216b	CLIP-seq
MIRT1293919	hsa-miR-296-3p	CLIP-seq
MIRT1293896	hsa-miR-302a	CLIP-seq
MIRT1293897	hsa-miR-302b	CLIP-seq
MIRT1293898	hsa-miR-302c	CLIP-seq
MIRT1293899	hsa-miR-302d	CLIP-seq
MIRT1293920	hsa-miR-323-3p	CLIP-seq
MIRT1293921	hsa-miR-323-5p	CLIP-seq
MIRT1293901	hsa-miR-3609	CLIP-seq
MIRT1293902	hsa-miR-3613-3p	CLIP-seq
MIRT1293903	hsa-miR-3671	CLIP-seq
MIRT1293904	hsa-miR-372	CLIP-seq
MIRT1293905	hsa-miR-373	CLIP-seq
MIRT1293922	hsa-miR-374c	CLIP-seq
MIRT1293906	hsa-miR-424	CLIP-seq
MIRT1293923	hsa-miR-4282	CLIP-seq
MIRT1293907	hsa-miR-4495	CLIP-seq
MIRT1293909	hsa-miR-4528	CLIP-seq
MIRT1293924	hsa-miR-4666-5p	CLIP-seq
MIRT1293910	hsa-miR-4699-3p	CLIP-seq
MIRT1293911	hsa-miR-4716-5p	CLIP-seq
MIRT1293912	hsa-miR-4753-3p	CLIP-seq
MIRT1293925	hsa-miR-4802-3p	CLIP-seq
MIRT1293926	hsa-miR-495	CLIP-seq
MIRT1293913	hsa-miR-497	CLIP-seq
MIRT1293914	hsa-miR-519a	CLIP-seq
MIRT1293915	hsa-miR-548ah	CLIP-seq
MIRT1293927	hsa-miR-548p	CLIP-seq
MIRT1293916	hsa-miR-548t	CLIP-seq
MIRT1293917	hsa-miR-616	CLIP-seq
MIRT1293918	hsa-miR-624	CLIP-seq
MIRT1293928	hsa-miR-655	CLIP-seq
MIRT2087367	hsa-miR-101	CLIP-seq
MIRT1293889	hsa-miR-103a	CLIP-seq
MIRT2087368	hsa-miR-144	CLIP-seq
MIRT1293895	hsa-miR-216b	CLIP-seq
MIRT2087369	hsa-miR-23a	CLIP-seq
MIRT2087370	hsa-miR-23b	CLIP-seq
MIRT2087371	hsa-miR-23c	CLIP-seq
MIRT1293896	hsa-miR-302a	CLIP-seq
MIRT1293897	hsa-miR-302b	CLIP-seq
MIRT1293898	hsa-miR-302c	CLIP-seq
MIRT1293899	hsa-miR-302d	CLIP-seq
MIRT1293920	hsa-miR-323-3p	CLIP-seq
MIRT2087372	hsa-miR-3647-3p	CLIP-seq
MIRT2087373	hsa-miR-3686	CLIP-seq
MIRT1293904	hsa-miR-372	CLIP-seq
MIRT1293905	hsa-miR-373	CLIP-seq
MIRT1293923	hsa-miR-4282	CLIP-seq
MIRT1293909	hsa-miR-4528	CLIP-seq
MIRT1293924	hsa-miR-4666-5p	CLIP-seq
MIRT1293910	hsa-miR-4699-3p	CLIP-seq
MIRT1293911	hsa-miR-4716-5p	CLIP-seq
MIRT2087374	hsa-miR-4778-5p	CLIP-seq
MIRT1293925	hsa-miR-4802-3p	CLIP-seq
MIRT2087375	hsa-miR-513a-3p	CLIP-seq
MIRT1293914	hsa-miR-519a	CLIP-seq
MIRT2087376	hsa-miR-582-5p	CLIP-seq
MIRT1293917	hsa-miR-616	CLIP-seq
MIRT1293918	hsa-miR-624	CLIP-seq
MIRT1293889	hsa-miR-103a	CLIP-seq
MIRT1293890	hsa-miR-15a	CLIP-seq
MIRT1293891	hsa-miR-15b	CLIP-seq
MIRT1293892	hsa-miR-16	CLIP-seq
MIRT1293893	hsa-miR-195	CLIP-seq
MIRT1293894	hsa-miR-2054	CLIP-seq
MIRT1293895	hsa-miR-216b	CLIP-seq
MIRT1293919	hsa-miR-296-3p	CLIP-seq
MIRT1293896	hsa-miR-302a	CLIP-seq
MIRT1293897	hsa-miR-302b	CLIP-seq
MIRT1293898	hsa-miR-302c	CLIP-seq
MIRT1293899	hsa-miR-302d	CLIP-seq
MIRT2312158	hsa-miR-3676	CLIP-seq
MIRT2087373	hsa-miR-3686	CLIP-seq
MIRT1293904	hsa-miR-372	CLIP-seq
MIRT1293905	hsa-miR-373	CLIP-seq
MIRT1293906	hsa-miR-424	CLIP-seq
MIRT2312159	hsa-miR-4291	CLIP-seq
MIRT2312160	hsa-miR-4452	CLIP-seq
MIRT1293909	hsa-miR-4528	CLIP-seq
MIRT1293924	hsa-miR-4666-5p	CLIP-seq
MIRT1293910	hsa-miR-4699-3p	CLIP-seq
MIRT1293911	hsa-miR-4716-5p	CLIP-seq
MIRT1293912	hsa-miR-4753-3p	CLIP-seq
MIRT2087374	hsa-miR-4778-5p	CLIP-seq
MIRT1293925	hsa-miR-4802-3p	CLIP-seq
MIRT1293913	hsa-miR-497	CLIP-seq
MIRT1293914	hsa-miR-519a	CLIP-seq
MIRT2312161	hsa-miR-545	CLIP-seq
MIRT1293917	hsa-miR-616	CLIP-seq
MIRT1293918	hsa-miR-624	CLIP-seq
MIRT1293889	hsa-miR-103a	CLIP-seq
MIRT2608713	hsa-miR-142-5p	CLIP-seq
MIRT1293890	hsa-miR-15a	CLIP-seq
MIRT1293891	hsa-miR-15b	CLIP-seq
MIRT1293892	hsa-miR-16	CLIP-seq
MIRT1293893	hsa-miR-195	CLIP-seq
MIRT1293896	hsa-miR-302a	CLIP-seq
MIRT1293897	hsa-miR-302b	CLIP-seq
MIRT1293898	hsa-miR-302c	CLIP-seq
MIRT1293899	hsa-miR-302d	CLIP-seq
MIRT1293900	hsa-miR-3171	CLIP-seq
MIRT2608714	hsa-miR-320a	CLIP-seq
MIRT2608715	hsa-miR-320b	CLIP-seq
MIRT2608716	hsa-miR-320c	CLIP-seq
MIRT2608717	hsa-miR-320d	CLIP-seq
MIRT2608718	hsa-miR-340	CLIP-seq
MIRT1293903	hsa-miR-3671	CLIP-seq
MIRT2312158	hsa-miR-3676	CLIP-seq
MIRT2087373	hsa-miR-3686	CLIP-seq
MIRT1293904	hsa-miR-372	CLIP-seq
MIRT1293905	hsa-miR-373	CLIP-seq
MIRT1293906	hsa-miR-424	CLIP-seq
MIRT2608719	hsa-miR-4429	CLIP-seq
MIRT1293907	hsa-miR-4495	CLIP-seq
MIRT1293908	hsa-miR-4502	CLIP-seq
MIRT1293909	hsa-miR-4528	CLIP-seq
MIRT1293910	hsa-miR-4699-3p	CLIP-seq
MIRT1293911	hsa-miR-4716-5p	CLIP-seq
MIRT2087374	hsa-miR-4778-5p	CLIP-seq
MIRT1293913	hsa-miR-497	CLIP-seq
MIRT1293914	hsa-miR-519a	CLIP-seq
MIRT1293917	hsa-miR-616	CLIP-seq
MIRT1293918	hsa-miR-624	CLIP-seq
MIRT2608713	hsa-miR-142-5p	CLIP-seq
MIRT1293890	hsa-miR-15a	CLIP-seq
MIRT1293891	hsa-miR-15b	CLIP-seq
MIRT1293892	hsa-miR-16	CLIP-seq
MIRT1293893	hsa-miR-195	CLIP-seq
MIRT1293900	hsa-miR-3171	CLIP-seq
MIRT2608714	hsa-miR-320a	CLIP-seq
MIRT2608715	hsa-miR-320b	CLIP-seq
MIRT2608716	hsa-miR-320c	CLIP-seq
MIRT2608717	hsa-miR-320d	CLIP-seq
MIRT2608718	hsa-miR-340	CLIP-seq
MIRT1293903	hsa-miR-3671	CLIP-seq
MIRT2312158	hsa-miR-3676	CLIP-seq
MIRT2087373	hsa-miR-3686	CLIP-seq
MIRT1293906	hsa-miR-424	CLIP-seq
MIRT2608719	hsa-miR-4429	CLIP-seq
MIRT1293907	hsa-miR-4495	CLIP-seq
MIRT1293908	hsa-miR-4502	CLIP-seq
MIRT2087374	hsa-miR-4778-5p	CLIP-seq
MIRT1293913	hsa-miR-497	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001701	Process	In utero embryonic development	IEA
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003723	Function	RNA binding	HDA	22681889
GO:0004842	Function	Ubiquitin-protein transferase activity	IDA	18851979
GO:0004842	Function	Ubiquitin-protein transferase activity	IEA
GO:0005515	Function	Protein binding	IPI	18624398, 18851979, 24726359, 32814053, 33961781
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005694	Component	Chromosome	IEA
GO:0005730	Component	Nucleolus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IDA	20873783
GO:0005813	Component	Centrosome	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IEA
GO:0006260	Process	DNA replication	IEA
GO:0006275	Process	Regulation of DNA replication	IMP	24726359
GO:0006397	Process	MRNA processing	IEA
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IBA
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IDA	18851979
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IEA
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IMP	24726359
GO:0006974	Process	DNA damage response	IEA
GO:0006974	Process	DNA damage response	IMP	24726359
GO:0008270	Function	Zinc ion binding	IEA
GO:0016567	Process	Protein ubiquitination	IBA
GO:0016567	Process	Protein ubiquitination	IEA
GO:0016607	Component	Nuclear speck	IDA
GO:0016740	Function	Transferase activity	IEA
GO:0019901	Function	Protein kinase binding	IPI	20873783
GO:0032991	Component	Protein-containing complex	IDA	20873783
GO:0035264	Process	Multicellular organism growth	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0048568	Process	Embryonic organ development	IEA
GO:0061053	Process	Somite development	IEA
GO:0061630	Function	Ubiquitin protein ligase activity	IBA
GO:0061630	Function	Ubiquitin protein ligase activity	IEA
GO:0061630	Function	Ubiquitin protein ligase activity	IMP	24726359

Other IDs

• MIM: 600938
• HGNC: 9889
• e!Ensembl: ENSG00000122257

Protein

• UniProt ID: Q7Z6E9
• Protein name: E3 ubiquitin-protein ligase RBBP6 (EC 2.3.2.27) (Proliferation potential-related protein) (Protein P2P-R) (RING-type E3 ubiquitin transferase RBBP6) (Retinoblastoma-binding Q protein 1) (RBQ-1) (Retinoblastoma-binding protein 6) (p53-associated cellular p
• Protein function: E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome (PubMed:18851979). May play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase
• PDB: 2C7H, 2YSA, 2YUR, 3ZTG, 6E5X
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF08783	DWNN	4 → 76	DWNN domain	Domain
  PF13696	zf-CCHC_2	156 → 176	Zinc knuckle	Domain
  PF04564	U-box	253 → 327	U-box domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Highly expressed in the placenta and testis. Expressed at lower levels in the brain, heart, kidney, liver and lung. Overexpressed in esophageal cancer. {ECO:0000269|PubMed:15475430}.
• Sequence:

  MSCVHYKFSSKLNYDTVTFDGLHISLCDLKKQIMGREKLKAADCDLQITNAQTKEEYTDD
  NALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAIDDSSASISLAQLTKTANL
  AEANASEEDKIKAMMSQSGHEYDPINYMKKPLGPPPPSYTCFRCGKPGHYIKNCPTNGDK
  NFESGPRIKKSTGIPRSFMMEVKDPNMKGAMLTNTGKYAIPTIDAEAYAIGKKEKPPFLP
  EEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHTCPTCH
  QNDVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPLMRS
  PISRQQDPLMIPVTSSSTHPAPSISSLTSNQSSLAPPVSGNPSSAPAPVPDITATVSISV
  HSEKSDGPFRDSDNKILPAAALASEHSKGTSSIAITALMEEKGYQVPVLGTPSLLGQSLL
  HGQLIPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSE
  RSQRTQGPSLPATPVFVPVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVP
  PPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEEEKKKSKLDE
  FTNDFAKELMEYKKIQKERRRSFSRSKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFS
  RSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQS
  PNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEK
  YYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPE
  KLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKS
  REPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTK
  RKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQK
  DEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPL
  DNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKI
  SLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEG
  SSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSK
  WDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDV
  SHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNF
  KSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDS
  PSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKS
  VDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSH
  SSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTA
  AVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKK
  HKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKSVTV

• Sequence length: 1792

Pathways

Reactome:

Antigen processing: Ubiquitination & Proteasome degradation

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
COLOR VISION DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OBESITY	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
RBBP6-related disorder	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenocarcinoma	Adenocarcinoma	BEFREE	17332367		★☆☆☆☆ Found in Text Mining only
Atrial Fibrillation	Atrial Fibrillation	BEFREE	28063245, 29379275		★☆☆☆☆ Found in Text Mining only
Autoimmune Diseases	Autoimmune Diseases	BEFREE	29032202		★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	24703106, 30237738, 31067223		★☆☆☆☆ Found in Text Mining only
Bronchioloalveolar Adenocarcinoma	Lung adenocarcinoma	BEFREE	17332367		★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	23799110	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	BEFREE	21676486		★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	21676486, 25127414		★☆☆☆☆ Found in Text Mining only
Carcinoma Ovarian Epithelial	Epithelial ovarian carcinoma	Pubtator	34132380	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	30305341		★☆☆☆☆ Found in Text Mining only
cervical cancer	Cervical Cancer	BEFREE	29501043		★☆☆☆☆ Found in Text Mining only
Cervix carcinoma	Cervix carcinoma	BEFREE	29501043		★☆☆☆☆ Found in Text Mining only
Colon Carcinoma	Colon Carcinoma	BEFREE	23799110, 26905308		★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Colonic neoplasm	Pubtator	23799110	Stimulate	★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	29369481, 31685801		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	23799110	Associate	★☆☆☆☆ Found in Text Mining only
Deep Vein Thrombosis	Thrombosis	BEFREE	28063245, 30607785		★☆☆☆☆ Found in Text Mining only
DYSTONIA 16 (disorder)	Dystonia	BEFREE	31246344		★☆☆☆☆ Found in Text Mining only
Dystonia Disorders	Dystonia	BEFREE	26231208		★☆☆☆☆ Found in Text Mining only
Encephalitis	Encephalitis	Pubtator	21061152	Associate	★☆☆☆☆ Found in Text Mining only
Encephalitis	Encephalitis	BEFREE	29032202		★☆☆☆☆ Found in Text Mining only
Esophageal carcinoma	Esophageal Carcinoma	BEFREE	15475430, 30223275		★☆☆☆☆ Found in Text Mining only
Esophageal Neoplasms	Esophagus Neoplasm	BEFREE	15475430, 30223275		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	25127414		★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung Neoplasms	BEFREE	21676486		★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	23799110	Stimulate	★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	25379943	Associate	★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	24703106, 30237738, 31067223		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of esophagus	Esophagus Neoplasm	BEFREE	15475430, 30223275		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	21676486, 25127414		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	30305341		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	25379943		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	15475430, 26905308, 29032202, 29501043, 31274515		★☆☆☆☆ Found in Text Mining only
Malignant tumor of cervix	Cervical Tumor	BEFREE	29501043		★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	23799110, 26905308		★☆☆☆☆ Found in Text Mining only
Mental disorders	Mental Disorders	BEFREE	29880047		★☆☆☆☆ Found in Text Mining only
Movement Disorders	Movement Disorders	BEFREE	31246344		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	15475430, 15617101, 21676486, 22139301, 24703106, 29369481, 30223275, 31685801		★☆☆☆☆ Found in Text Mining only
Neurodegenerative Disorders	Neurodegenerative Disorders	BEFREE	29170442		★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	30305341		★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	37322627	Associate	★☆☆☆☆ Found in Text Mining only
Peripheral Arterial Diseases	Vascular Diseases	BEFREE	27771367		★☆☆☆☆ Found in Text Mining only
Peripheral arterial stenosis	Peripheral arterial stenosis	BEFREE	27771367		★☆☆☆☆ Found in Text Mining only
Retinoblastoma	Retinoblastoma	BEFREE	15617101, 17454639, 22139301		★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma	Carcinoma	BEFREE	17332367		★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	25379943		★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	25379943	Associate	★☆☆☆☆ Found in Text Mining only