| GO ID |
Ontology |
Definition |
Evidence |
Reference |
| GO:0000976 |
Function |
Transcription cis-regulatory region binding |
IDA |
16603732 |
| GO:0005515 |
Function |
Protein binding |
IPI |
12482968, 14992727, 15199122, 15960975, 16603732, 16892064, 17041588, 17178841, 17500065, 17925232, 17998332, 18838538, 19131338, 19187761, 19556245, 20085832, 21220120, 21516116, 23414517, 23870121, 24981860, 25416956, 26496610, 26886794, 27705803, 32296183, 33961781, 37725512 |
| GO:0005634 |
Component |
Nucleus |
IDA |
15199122, 17500065 |
| GO:0005634 |
Component |
Nucleus |
IEA |
|
| GO:0005654 |
Component |
Nucleoplasm |
IDA |
|
| GO:0005654 |
Component |
Nucleoplasm |
IEA |
|
| GO:0005654 |
Component |
Nucleoplasm |
TAS |
|
| GO:0005730 |
Component |
Nucleolus |
IDA |
|
| GO:0006325 |
Process |
Chromatin organization |
IEA |
|
| GO:0006974 |
Process |
DNA damage response |
IDA |
17500065 |
| GO:0035097 |
Component |
Histone methyltransferase complex |
IDA |
17355966, 17500065, 19556245 |
| GO:0042393 |
Function |
Histone binding |
IDA |
15960975 |
| GO:0043627 |
Process |
Response to estrogen |
IDA |
16603732 |
| GO:0044665 |
Component |
MLL1/2 complex |
IPI |
23508102 |
| GO:0044666 |
Component |
MLL3/4 complex |
IDA |
17500065 |
| GO:0044666 |
Component |
MLL3/4 complex |
IPI |
23508102 |
| GO:0045815 |
Process |
Transcription initiation-coupled chromatin remodeling |
IDA |
19556245 |
| GO:0048188 |
Component |
Set1C/COMPASS complex |
IBA |
|
| GO:0048188 |
Component |
Set1C/COMPASS complex |
IDA |
17998332, 18838538 |
| GO:0048188 |
Component |
Set1C/COMPASS complex |
IEA |
|
| GO:0048188 |
Component |
Set1C/COMPASS complex |
IPI |
23508102 |
| GO:0071339 |
Component |
MLL1 complex |
IDA |
15960975 |
| GO:0071339 |
Component |
MLL1 complex |
IPI |
23508102 |
|
|
UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
|
Q15291 |
| Protein name |
Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3) |
| Protein function |
In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid |
| PDB |
3P4F
, 4X8N
, 4X8P
, 5F6K
, 5F6L
, 6KIU
, 6KIV
, 6KIW
, 6KIX
, 6KIZ
, 6KM7
, 6PWV
, 6PWW
, 6PWX
, 6W5I
, 6W5M
, 6W5N
, 7BRE
, 7MBM
, 7MBN
, 7UD5
, 7W67
, 7W6A
, 7W6I
, 7W6J
, 7W6L
, 8DU4
|
| Family and domains |
Pfam
| Accession |
ID |
Position in sequence |
Description |
Type |
| PF00400 |
WD40 |
58 → 94 |
WD domain, G-beta repeat |
Repeat |
|
| Tissue specificity |
TISSUE SPECIFICITY: Ubiquitously expressed. |
| Sequence |
MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAK IISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQ NKVLVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKT DSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPE PMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLD VAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKS EPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPP DAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSK KKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAKGKVQAELSQPLTAGGAISELL
|
|
| Sequence length |
538 |
| Interactions |
View interactions |