EVA1C (eva-1 homolog C)

Gene Gene information from NCBI Gene database.
Gene Gene ontology Other IDs Protein Associated diseases
Entrez ID 59271
Gene name Eva-1 homolog C
Gene symbol EVA1C
Synonyms (NCBI Gene)
B18B19C21orf63C21orf64FAM176CPRED34SUE21
Chromosome 21
Chromosome location 21q22.11
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
6
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide all (6)
GO ID Ontology Definition Evidence Reference
GO:0005576 Component Extracellular region IBA
GO:0005576 Component Extracellular region IDA 19470522
GO:0008201 Function Heparin binding IBA
GO:0008201 Function Heparin binding IMP 19470522
GO:0016020 Component Membrane IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
Gene Gene ontology Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P58658
Protein name Protein eva-1 homolog C (Protein FAM176C) (SUE21)
Protein function Binds heparin.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02140 Gal_Lectin 75 → 158 Galactose binding lectin domain Domain
PF02140 Gal_Lectin 176 → 259 Galactose binding lectin domain Domain
PF14851 FAM176 301 → 441 FAM176 family Family
Tissue specificity TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:19470522}.
Sequence
Sequence length 441
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
4
Gene Gene ontology Other IDs Protein Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (4)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
CEREBRAL AMYLOID ANGIOPATHY — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
HEPATITIS VIRUS-RELATED HEPATOCELLULAR CARCINOMA — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma Likely benign ClinVar
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
NEUROBLASTOMA — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Show/Hide Text Mining Associations (7)
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Adenocarcinoma Adenocarcinoma BEFREE 17459020
★★★★★
★☆☆☆☆
Found in Text Mining only
Arthritis Rheumatoid Rheumatoid arthritis Pubtator 28358698 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Astrocytoma Astrocytoma Pubtator 34267752 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Carcinoma Hepatocellular Hepatocellular carcinoma Pubtator 33736632 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Glioma Glioma Pubtator 34267752 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Hemoglobinopathies Hemoglobinopathy BEFREE 15976179
★★★★★
★☆☆☆☆
Found in Text Mining only
Hepatitis B Chronic Hepatitis b Pubtator 33736632 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only