Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	5872
Gene name	RAB13, member RAS oncogene family
Gene symbol	RAB13
Synonyms (NCBI Gene)	GIG4
Chromosome	1
Chromosome location	1q21.3
Summary	This gene is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE). The encoded protein is involved in the assembly of tight junctions, which are c

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miRTarBase ID	miRNA	Experiments	Reference
MIRT005472	ebv-miR-BART16	ImmunoprecipitaionLuciferase reporter assayMicroarrayqRT-PCR	20413099
MIRT005473	ebv-miR-BART3-3p	ImmunoprecipitaionLuciferase reporter assayMicroarrayqRT-PCR	20413099
MIRT007119	hsa-miR-19a-3p	Luciferase reporter assay	23451058
MIRT052605	hsa-let-7a-5p	CLASH	23622248
MIRT040836	hsa-miR-18a-3p	CLASH	23622248
MIRT038865	hsa-miR-93-3p	CLASH	23622248
MIRT700404	hsa-miR-3929	HITS-CLIP	23313552
MIRT700402	hsa-miR-4419b	HITS-CLIP	23313552
MIRT700403	hsa-miR-4478	HITS-CLIP	23313552
MIRT700401	hsa-miR-6767-3p	HITS-CLIP	23313552
MIRT700400	hsa-miR-5690	HITS-CLIP	23313552
MIRT700399	hsa-miR-6746-5p	HITS-CLIP	23313552
MIRT700398	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT700397	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT700396	hsa-miR-214-5p	HITS-CLIP	23313552
MIRT700395	hsa-miR-6811-3p	HITS-CLIP	23313552
MIRT700394	hsa-miR-564	HITS-CLIP	23313552
MIRT700393	hsa-miR-1271-3p	HITS-CLIP	23313552
MIRT700392	hsa-miR-550a-3-5p	HITS-CLIP	23313552
MIRT700391	hsa-miR-550a-5p	HITS-CLIP	23313552
MIRT700390	hsa-miR-891a-3p	HITS-CLIP	23313552
MIRT700388	hsa-miR-7977	HITS-CLIP	23313552
MIRT700389	hsa-miR-6771-5p	HITS-CLIP	23313552
MIRT700387	hsa-miR-6514-3p	HITS-CLIP	23313552
MIRT700386	hsa-miR-665	HITS-CLIP	23313552
MIRT640918	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT640917	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT640916	hsa-miR-5193	HITS-CLIP	23824327
MIRT640915	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT640914	hsa-miR-3183	HITS-CLIP	23824327
MIRT640913	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT640911	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT640912	hsa-miR-4469	HITS-CLIP	23824327
MIRT640910	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT640909	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT640908	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT640907	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT640906	hsa-miR-155-3p	HITS-CLIP	23824327
MIRT640905	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT640904	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT640903	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT640901	hsa-miR-3685	HITS-CLIP	23824327
MIRT640902	hsa-miR-670-3p	HITS-CLIP	23824327
MIRT640900	hsa-miR-1238-3p	HITS-CLIP	23824327
MIRT632508	hsa-miR-1245a	HITS-CLIP	23824327
MIRT632507	hsa-miR-8079	HITS-CLIP	23824327
MIRT632506	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT632505	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT632504	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT632503	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT632502	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT632501	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT632500	hsa-miR-4795-5p	HITS-CLIP	23824327
MIRT632499	hsa-miR-3616-5p	HITS-CLIP	23824327
MIRT632498	hsa-miR-573	HITS-CLIP	23824327
MIRT528746	hsa-miR-590-3p	PAR-CLIP	22012620
MIRT528739	hsa-miR-411-5p	PAR-CLIP	22012620
MIRT528745	hsa-miR-6890-5p	PAR-CLIP	22012620
MIRT528744	hsa-miR-4735-5p	PAR-CLIP	22012620
MIRT528743	hsa-miR-1273f	PAR-CLIP	22012620
MIRT528742	hsa-miR-193b-5p	PAR-CLIP	22012620
MIRT528741	hsa-miR-6832-5p	PAR-CLIP	22012620
MIRT528740	hsa-miR-4775	PAR-CLIP	22012620
MIRT528739	hsa-miR-411-5p	PAR-CLIP	22012620
MIRT528738	hsa-miR-3170	PAR-CLIP	22012620
MIRT528737	hsa-miR-6855-5p	PAR-CLIP	22012620
MIRT528736	hsa-miR-3149	PAR-CLIP	22012620
MIRT528735	hsa-miR-129-5p	PAR-CLIP	22012620
MIRT640917	hsa-miR-2276-5p	qRT-PCRWestern blotting	34141710
MIRT700404	hsa-miR-3929	HITS-CLIP	23313552
MIRT700402	hsa-miR-4419b	HITS-CLIP	23313552
MIRT700403	hsa-miR-4478	HITS-CLIP	23313552
MIRT700401	hsa-miR-6767-3p	HITS-CLIP	23313552
MIRT700400	hsa-miR-5690	HITS-CLIP	23313552
MIRT700399	hsa-miR-6746-5p	HITS-CLIP	23313552
MIRT700398	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT700397	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT700396	hsa-miR-214-5p	HITS-CLIP	23313552
MIRT700395	hsa-miR-6811-3p	HITS-CLIP	23313552
MIRT700394	hsa-miR-564	HITS-CLIP	23313552
MIRT700393	hsa-miR-1271-3p	HITS-CLIP	23313552
MIRT700392	hsa-miR-550a-3-5p	HITS-CLIP	23313552
MIRT700391	hsa-miR-550a-5p	HITS-CLIP	23313552
MIRT700390	hsa-miR-891a-3p	HITS-CLIP	23313552
MIRT700388	hsa-miR-7977	HITS-CLIP	23313552
MIRT700389	hsa-miR-6771-5p	HITS-CLIP	23313552
MIRT700387	hsa-miR-6514-3p	HITS-CLIP	23313552
MIRT700386	hsa-miR-665	HITS-CLIP	23313552
MIRT640918	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT640917	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT640916	hsa-miR-5193	HITS-CLIP	23824327
MIRT640915	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT640914	hsa-miR-3183	HITS-CLIP	23824327
MIRT640913	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT640911	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT640912	hsa-miR-4469	HITS-CLIP	23824327
MIRT640910	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT640909	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT640908	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT640907	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT640906	hsa-miR-155-3p	HITS-CLIP	23824327
MIRT640905	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT640904	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT640903	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT640901	hsa-miR-3685	HITS-CLIP	23824327
MIRT640902	hsa-miR-670-3p	HITS-CLIP	23824327
MIRT640900	hsa-miR-1238-3p	HITS-CLIP	23824327
MIRT632508	hsa-miR-1245a	HITS-CLIP	23824327
MIRT632507	hsa-miR-8079	HITS-CLIP	23824327
MIRT632506	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT632505	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT632504	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT632503	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT632502	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT632501	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT632500	hsa-miR-4795-5p	HITS-CLIP	23824327
MIRT632499	hsa-miR-3616-5p	HITS-CLIP	23824327
MIRT632498	hsa-miR-573	HITS-CLIP	23824327
MIRT528746	hsa-miR-590-3p	PAR-CLIP	22012620
MIRT528739	hsa-miR-411-5p	PAR-CLIP	22012620
MIRT528745	hsa-miR-6890-5p	PAR-CLIP	22012620
MIRT528744	hsa-miR-4735-5p	PAR-CLIP	22012620
MIRT528743	hsa-miR-1273f	PAR-CLIP	22012620
MIRT528742	hsa-miR-193b-5p	PAR-CLIP	22012620
MIRT528741	hsa-miR-6832-5p	PAR-CLIP	22012620
MIRT528740	hsa-miR-4775	PAR-CLIP	22012620
MIRT528739	hsa-miR-411-5p	PAR-CLIP	22012620
MIRT528738	hsa-miR-3170	PAR-CLIP	22012620
MIRT528737	hsa-miR-6855-5p	PAR-CLIP	22012620
MIRT528736	hsa-miR-3149	PAR-CLIP	22012620
MIRT528735	hsa-miR-129-5p	PAR-CLIP	22012620
MIRT1281667	hsa-miR-1236	CLIP-seq
MIRT1281668	hsa-miR-1238	CLIP-seq
MIRT1281669	hsa-miR-1286	CLIP-seq
MIRT1281670	hsa-miR-142-3p	CLIP-seq
MIRT1281671	hsa-miR-146b-3p	CLIP-seq
MIRT1281672	hsa-miR-1827	CLIP-seq
MIRT1281673	hsa-miR-194	CLIP-seq
MIRT1281674	hsa-miR-3157-3p	CLIP-seq
MIRT1281675	hsa-miR-3173-5p	CLIP-seq
MIRT1281676	hsa-miR-325	CLIP-seq
MIRT1281677	hsa-miR-3614-3p	CLIP-seq
MIRT1281678	hsa-miR-3667-3p	CLIP-seq
MIRT1281679	hsa-miR-371-3p	CLIP-seq
MIRT1281680	hsa-miR-371b-3p	CLIP-seq
MIRT1281681	hsa-miR-3938	CLIP-seq
MIRT1281682	hsa-miR-4280	CLIP-seq
MIRT1281683	hsa-miR-4302	CLIP-seq
MIRT1281684	hsa-miR-4307	CLIP-seq
MIRT1281685	hsa-miR-450b-5p	CLIP-seq
MIRT1281686	hsa-miR-4699-3p	CLIP-seq
MIRT1281687	hsa-miR-4722-5p	CLIP-seq
MIRT1281688	hsa-miR-4726-3p	CLIP-seq
MIRT1281689	hsa-miR-4729	CLIP-seq
MIRT1281690	hsa-miR-4773	CLIP-seq
MIRT1281691	hsa-miR-507	CLIP-seq
MIRT1281692	hsa-miR-515-3p	CLIP-seq
MIRT1281693	hsa-miR-519e	CLIP-seq
MIRT1281694	hsa-miR-548aa	CLIP-seq
MIRT1281695	hsa-miR-557	CLIP-seq
MIRT1281696	hsa-miR-570	CLIP-seq
MIRT1281697	hsa-miR-628-3p	CLIP-seq
MIRT1281698	hsa-miR-642a	CLIP-seq
MIRT1281699	hsa-miR-802	CLIP-seq
MIRT1281700	hsa-miR-874	CLIP-seq
MIRT1281668	hsa-miR-1238	CLIP-seq
MIRT1281671	hsa-miR-146b-3p	CLIP-seq
MIRT2083257	hsa-miR-31	CLIP-seq
MIRT2083258	hsa-miR-3150a-3p	CLIP-seq
MIRT1281674	hsa-miR-3157-3p	CLIP-seq
MIRT1281675	hsa-miR-3173-5p	CLIP-seq
MIRT2083259	hsa-miR-3175	CLIP-seq
MIRT1281676	hsa-miR-325	CLIP-seq
MIRT2083260	hsa-miR-3612	CLIP-seq
MIRT1281678	hsa-miR-3667-3p	CLIP-seq
MIRT1281681	hsa-miR-3938	CLIP-seq
MIRT1281684	hsa-miR-4307	CLIP-seq
MIRT2083261	hsa-miR-4651	CLIP-seq
MIRT1281689	hsa-miR-4729	CLIP-seq
MIRT2083262	hsa-miR-491-5p	CLIP-seq
MIRT1281696	hsa-miR-570	CLIP-seq
MIRT2083263	hsa-miR-608	CLIP-seq
MIRT1281697	hsa-miR-628-3p	CLIP-seq
MIRT1281698	hsa-miR-642a	CLIP-seq
MIRT2083264	hsa-miR-650	CLIP-seq
MIRT1281699	hsa-miR-802	CLIP-seq
MIRT1281700	hsa-miR-874	CLIP-seq
MIRT2083265	hsa-miR-939	CLIP-seq
MIRT1281669	hsa-miR-1286	CLIP-seq
MIRT1281670	hsa-miR-142-3p	CLIP-seq
MIRT1281673	hsa-miR-194	CLIP-seq
MIRT2083257	hsa-miR-31	CLIP-seq
MIRT2083258	hsa-miR-3150a-3p	CLIP-seq
MIRT2083259	hsa-miR-3175	CLIP-seq
MIRT2083260	hsa-miR-3612	CLIP-seq
MIRT1281677	hsa-miR-3614-3p	CLIP-seq
MIRT1281679	hsa-miR-371-3p	CLIP-seq
MIRT1281680	hsa-miR-371b-3p	CLIP-seq
MIRT1281682	hsa-miR-4280	CLIP-seq
MIRT1281683	hsa-miR-4302	CLIP-seq
MIRT1281684	hsa-miR-4307	CLIP-seq
MIRT2308625	hsa-miR-4497	CLIP-seq
MIRT1281685	hsa-miR-450b-5p	CLIP-seq
MIRT2083261	hsa-miR-4651	CLIP-seq
MIRT1281686	hsa-miR-4699-3p	CLIP-seq
MIRT1281687	hsa-miR-4722-5p	CLIP-seq
MIRT1281689	hsa-miR-4729	CLIP-seq
MIRT2083262	hsa-miR-491-5p	CLIP-seq
MIRT1281691	hsa-miR-507	CLIP-seq
MIRT1281692	hsa-miR-515-3p	CLIP-seq
MIRT1281693	hsa-miR-519e	CLIP-seq
MIRT1281695	hsa-miR-557	CLIP-seq
MIRT2083263	hsa-miR-608	CLIP-seq
MIRT2083264	hsa-miR-650	CLIP-seq
MIRT2083265	hsa-miR-939	CLIP-seq
MIRT2605711	hsa-miR-1178	CLIP-seq
MIRT1281668	hsa-miR-1238	CLIP-seq
MIRT1281671	hsa-miR-146b-3p	CLIP-seq
MIRT1281672	hsa-miR-1827	CLIP-seq
MIRT1281673	hsa-miR-194	CLIP-seq
MIRT2083257	hsa-miR-31	CLIP-seq
MIRT2083258	hsa-miR-3150a-3p	CLIP-seq
MIRT1281674	hsa-miR-3157-3p	CLIP-seq
MIRT1281675	hsa-miR-3173-5p	CLIP-seq
MIRT2083259	hsa-miR-3175	CLIP-seq
MIRT1281676	hsa-miR-325	CLIP-seq
MIRT2605712	hsa-miR-331-3p	CLIP-seq
MIRT2083260	hsa-miR-3612	CLIP-seq
MIRT1281678	hsa-miR-3667-3p	CLIP-seq
MIRT2605713	hsa-miR-3974	CLIP-seq
MIRT2605714	hsa-miR-4287	CLIP-seq
MIRT2605715	hsa-miR-4293	CLIP-seq
MIRT1281683	hsa-miR-4302	CLIP-seq
MIRT1281684	hsa-miR-4307	CLIP-seq
MIRT2308625	hsa-miR-4497	CLIP-seq
MIRT2605716	hsa-miR-4649-3p	CLIP-seq
MIRT2083261	hsa-miR-4651	CLIP-seq
MIRT2605717	hsa-miR-4685-3p	CLIP-seq
MIRT1281686	hsa-miR-4699-3p	CLIP-seq
MIRT2605718	hsa-miR-4713-5p	CLIP-seq
MIRT2605719	hsa-miR-4725-5p	CLIP-seq
MIRT1281688	hsa-miR-4726-3p	CLIP-seq
MIRT1281689	hsa-miR-4729	CLIP-seq
MIRT2605720	hsa-miR-4749-3p	CLIP-seq
MIRT2605721	hsa-miR-4786-3p	CLIP-seq
MIRT2605722	hsa-miR-483-3p	CLIP-seq
MIRT2083262	hsa-miR-491-5p	CLIP-seq
MIRT2605723	hsa-miR-504	CLIP-seq
MIRT2605724	hsa-miR-544b	CLIP-seq
MIRT1281696	hsa-miR-570	CLIP-seq
MIRT2083263	hsa-miR-608	CLIP-seq
MIRT1281697	hsa-miR-628-3p	CLIP-seq
MIRT1281698	hsa-miR-642a	CLIP-seq
MIRT2083264	hsa-miR-650	CLIP-seq
MIRT2605725	hsa-miR-767-3p	CLIP-seq
MIRT1281699	hsa-miR-802	CLIP-seq
MIRT1281700	hsa-miR-874	CLIP-seq
MIRT2083265	hsa-miR-939	CLIP-seq
MIRT2605711	hsa-miR-1178	CLIP-seq
MIRT1281671	hsa-miR-146b-3p	CLIP-seq
MIRT2083257	hsa-miR-31	CLIP-seq
MIRT2083258	hsa-miR-3150a-3p	CLIP-seq
MIRT1281674	hsa-miR-3157-3p	CLIP-seq
MIRT1281675	hsa-miR-3173-5p	CLIP-seq
MIRT2083259	hsa-miR-3175	CLIP-seq
MIRT2605712	hsa-miR-331-3p	CLIP-seq
MIRT2083260	hsa-miR-3612	CLIP-seq
MIRT2605714	hsa-miR-4287	CLIP-seq
MIRT2308625	hsa-miR-4497	CLIP-seq
MIRT2083261	hsa-miR-4651	CLIP-seq
MIRT2605717	hsa-miR-4685-3p	CLIP-seq
MIRT2605718	hsa-miR-4713-5p	CLIP-seq
MIRT2605719	hsa-miR-4725-5p	CLIP-seq
MIRT1281688	hsa-miR-4726-3p	CLIP-seq
MIRT2605720	hsa-miR-4749-3p	CLIP-seq
MIRT2605722	hsa-miR-483-3p	CLIP-seq
MIRT2083262	hsa-miR-491-5p	CLIP-seq
MIRT2605723	hsa-miR-504	CLIP-seq
MIRT1281696	hsa-miR-570	CLIP-seq
MIRT2083263	hsa-miR-608	CLIP-seq
MIRT1281698	hsa-miR-642a	CLIP-seq
MIRT2083264	hsa-miR-650	CLIP-seq
MIRT2605725	hsa-miR-767-3p	CLIP-seq
MIRT1281700	hsa-miR-874	CLIP-seq
MIRT2083265	hsa-miR-939	CLIP-seq

Show/Hide all (62)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0003924	Function	GTPase activity	IBA
GO:0003924	Function	GTPase activity	IDA	8294494
GO:0003924	Function	GTPase activity	IEA
GO:0005515	Function	Protein binding	IPI	9712853, 16525024, 18332111, 20008558, 21795389, 23772379
GO:0005525	Function	GTP binding	IDA	20937701
GO:0005525	Function	GTP binding	IEA
GO:0005768	Component	Endosome	IBA
GO:0005768	Component	Endosome	IEA
GO:0005794	Component	Golgi apparatus	IDA	18779367
GO:0005802	Component	Trans-Golgi network	IDA	18779367
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	15528189, 18779367
GO:0005886	Component	Plasma membrane	IEA
GO:0005911	Component	Cell-cell junction	IEA
GO:0005923	Component	Bicellular tight junction	IDA	8294494
GO:0005923	Component	Bicellular tight junction	IEA
GO:0006887	Process	Exocytosis	IBA
GO:0006893	Process	Golgi to plasma membrane transport	IDA	35343654
GO:0008021	Component	Synaptic vesicle	IBA
GO:0008104	Process	Intracellular protein localization	IEA
GO:0010737	Process	Protein kinase A signaling	IBA
GO:0010737	Process	Protein kinase A signaling	IMP	15096524
GO:0015031	Process	Protein transport	IEA
GO:0016020	Component	Membrane	IEA
GO:0016197	Process	Endosomal transport	IMP	18779367
GO:0016328	Component	Lateral plasma membrane	IDA
GO:0016787	Function	Hydrolase activity	IEA
GO:0030027	Component	Lamellipodium	IEA
GO:0030027	Component	Lamellipodium	ISS
GO:0030054	Component	Cell junction	TAS
GO:0030139	Component	Endocytic vesicle	IDA	15528189
GO:0030139	Component	Endocytic vesicle	IEA
GO:0030140	Component	Trans-Golgi network transport vesicle	IBA
GO:0030659	Component	Cytoplasmic vesicle membrane	IEA
GO:0030866	Process	Cortical actin cytoskeleton organization	ISS
GO:0031175	Process	Neuron projection development	IMP	20008558
GO:0031410	Component	Cytoplasmic vesicle	IDA	8294494
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0032456	Process	Endocytic recycling	IBA
GO:0032456	Process	Endocytic recycling	IEA
GO:0032456	Process	Endocytic recycling	IMP	15528189
GO:0032593	Component	Insulin-responsive compartment	ISS
GO:0032869	Process	Cellular response to insulin stimulus	ISS
GO:0034142	Process	Toll-like receptor 4 signaling pathway	IDA	10196138
GO:0035767	Process	Endothelial cell chemotaxis	IEA
GO:0035767	Process	Endothelial cell chemotaxis	ISS
GO:0042995	Component	Cell projection	IEA
GO:0043005	Component	Neuron projection	IDA	20008558
GO:0044795	Process	Trans-Golgi network to recycling endosome transport	ISS
GO:0046872	Function	Metal ion binding	IEA
GO:0051668	Process	Localization within membrane	IEA
GO:0055037	Component	Recycling endosome	IDA	18779367
GO:0055038	Component	Recycling endosome membrane	IEA
GO:0070062	Component	Extracellular exosome	HDA	19056867
GO:0070161	Component	Anchoring junction	IEA
GO:0070830	Process	Bicellular tight junction assembly	IMP	15096524
GO:0072659	Process	Protein localization to plasma membrane	IMP	15096524
GO:0097368	Process	Establishment of Sertoli cell barrier	ISS
GO:1902463	Process	Protein localization to cell leading edge	IEA

MIM	HGNC	e!Ensembl
602672	9762	ENSG00000143545

P51153

Protein name

Ras-related protein Rab-13 (EC 3.6.5.2) (Cell growth-inhibiting gene 4 protein)

Protein function

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to r

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00071	Ras	10 → 171	Ras family	Domain

Tissue specificity

TISSUE SPECIFICITY: Detected in several types of epithelia, including intestine, kidney, liver and in endothelial cells. {ECO:0000269|PubMed:8294494}.

Sequence

MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQ
VWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLG
NKCDMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLKSGGRRSGN
GNKPPSTDLKTCDKKNTNKCSLG

Sequence length

203

Interactions

View interactions

	KEGG		Reactome
	Tight junction		RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
PROSTATE CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (11)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	36901767, 37803063	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	30332650, 32978434, 39192986	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	24967941		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	34632655	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	31474334		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	27044746, 28498422		★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	BEFREE	31849524		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	37046345	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Peritonitis	Peritonitis	Pubtator	39192986	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	31474334		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	37803063	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

RAB13 (RAB13, member RAS oncogene family)