Gene Gene information from NCBI Gene database.
Entrez ID 58526
Gene name MID1 interacting protein 1
Gene symbol MID1IP1
Synonyms (NCBI Gene)
G12-likeMIG12S14RSTRAIT11499THRSPL
Chromosome X
Chromosome location Xp11.4
miRNA miRNA information provided by mirtarbase database.
407
miRTarBase ID miRNA Experiments Reference
MIRT003160 hsa-miR-210-3p immunoprecipitaionMicroarrayqRT-PCR 19826008
MIRT020221 hsa-miR-130b-3p Sequencing 20371350
MIRT031163 hsa-miR-19b-3p Sequencing 20371350
MIRT040447 hsa-miR-615-3p CLASH 23622248
MIRT109826 hsa-miR-19a-3p HITS-CLIP 21572407
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
24
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 16189514, 25416956, 28298427, 33961781
GO:0005634 Component Nucleus IEA
GO:0005737 Component Cytoplasm IEA
GO:0005829 Component Cytosol IBA
GO:0005829 Component Cytosol IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
300961 20715 ENSG00000165175
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9NPA3
Protein name Mid1-interacting protein 1 (Gastrulation-specific G12-like protein) (Mid1-interacting G12-like protein) (Protein STRAIT11499) (Spot 14-related protein) (S14R) (Spot 14-R)
Protein function Plays a role in the regulation of lipogenesis in liver. Up-regulates ACACA enzyme activity. Required for efficient lipid biosynthesis, including triacylglycerol, diacylglycerol and phospholipid. Involved in stabilization of microtubules (By simi
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07084 Spot_14 2 179 Thyroid hormone-inducible hepatic protein Spot 14 Family
Sequence
Sequence length 183
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Carnitine metabolism
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
Flexion contracture Uncertain significance ClinVar
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
LIVER CIRRHOSIS, EXPERIMENTAL CTD
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Androgen-Insensitivity Syndrome Androgen-Insensitivity Syndrome BEFREE 27082501
★☆☆☆☆
Found in Text Mining only
Carcinoma Hepatocellular Hepatocellular carcinoma Pubtator 32316188 Associate
★☆☆☆☆
Found in Text Mining only
Colorectal Neoplasms Colorectal neoplasm Pubtator 34680125, 37110707 Associate
★☆☆☆☆
Found in Text Mining only
Fatty Liver Fatty Liver BEFREE 30700011
★☆☆☆☆
Found in Text Mining only
Hyperlipidemia Hyperlipidemia BEFREE 30700011
★☆☆☆☆
Found in Text Mining only
Opitz GBBB Syndrome, X-Linked Opitz GBBB Syndrome, X-Linked BEFREE 15070402
★☆☆☆☆
Found in Text Mining only
Steatohepatitis Fatty Liver BEFREE 30700011
★☆☆☆☆
Found in Text Mining only
Thyroid Neoplasms Thyroid cancer Pubtator 36281116 Associate
★☆☆☆☆
Found in Text Mining only