Gene Gene information from NCBI Gene database.
Entrez ID 57710
Gene name KIAA1614
Gene symbol KIAA1614
Synonyms (NCBI Gene)
-
Chromosome 1
Chromosome location 1q25.3
miRNA miRNA information provided by mirtarbase database.
242
miRTarBase ID miRNA Experiments Reference
MIRT687721 hsa-miR-590-3p HITS-CLIP 23313552
MIRT687719 hsa-miR-1295b-3p HITS-CLIP 23313552
MIRT687718 hsa-miR-4787-3p HITS-CLIP 23313552
MIRT493379 hsa-miR-4735-5p HITS-CLIP 23313552
MIRT687717 hsa-miR-4775 HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
6
GO ID Ontology Definition Evidence Reference
GO:0005634 Component Nucleus IBA
GO:0005938 Component Cell cortex IBA
GO:0007098 Process Centrosome cycle IBA
GO:0007163 Process Establishment or maintenance of cell polarity IBA
GO:0016324 Component Apical plasma membrane IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q5VZ46
Protein name Uncharacterized protein KIAA1614
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15737 DUF4685 354 478 Domain of unknown function (DUF4685) Family
Sequence
MEGTEAAAAKPAGGSPQGPKTGSGTASPVEGTSAVEWSGPEPQLDNGHPPRPWPCPQENR
TSSLMAPQPPRVWGVQLQGPSVLESKVRALKEKMTVAKQGVSPCSASQEWSSPKKPQCRR
GKAGRAGTPSEGSFLPGAVVAPRTQNLPDGQLDGSINEEQPARDGGPRLPRPPAPGREYC
NRGSPWPPEAEWTLPDHDRGPLLGPSSLQQSPIHGVTPGRPGGPGHCNKIIHIPSPRTGR
SYPFPDGVVTEADLDSTSLTSEEVFVPRTALLGERWRAGDLEALGAGSSVLSLSDRVERN
RLLLQEMLNVSGQSPRKVGTPAWTPSWDTAAPERPVGDVDWASGTSLQDSGQNRTVGPNP
EPVLSPRHEEATHLLQRARMKARTRPLRASHDIVPTITQGSRDGHRSPARDPRTTPACRD
SLQNGHTSDSSSGESSGGHRPRRGPSPSHVRFEDESAREAEFRHLERLQQRQRQVLST
VL
QAADQGPLRSKPDLADYINGAPRLRDAGQGTFHRLVGSLDRRGHPAPPAPGSERRCQACG
SCIDDPRPAQGKAPPVPRTLQELQAACGMERVLGGLSSPLRLLPAEPRLHMEWIRETHIG
DTVCPAEVDSALDSTDNSDNCRTDSEEAGTSQAGWACGRTQGSSPRLRLRGSRPRGHRWS
KKAEAELPWGLQAQQHLPRADDVEVENEVKEGRGHTPEGTLFLREDAKPPDLELKRVSLG
PQWQPGPGLGSHQPHPLDSRTPCRTAYATTAPMTPESSGPGGQAQVTESHESLEIVSPSS
LQQSHAEPSAPHQAWQPTASLCPEGWAPTPPPSRKTTSPVSHRKAALAGLLRLGDQTEPV
GIPRPPSRSAVLRTCELPPSQTQPSRPQVRHPLLALSTNNCNNSAPRGLQEPYGGAVHEG
RVERGPCSREPEPPLENSRDGGPQGFLGSADVATINSTGITLSLSSEESESSKESEGSLQ
RTGSGSGGHVLSRASAGAGTGPGSPSAAPLDQNKKRSSSIASTLGLKKLFSALGQSSRPK
LGKSRSYSVEQLQPAPPGLTSQSRAPSLQSLHPVSPSHQRRKAASFQNLHSLLSSKGNRS
SLYLVAGPGDHSAAGRPAKTSPRRALSVEDVGAPSLARTVGRLVEVFPDGTSQLQLQRSP
GGTFGFCVASGNGRPDSGMPSPLPQPHGWGGLSKQGRAFWLWSEAFLVFG
Sequence length 1190
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
IDIOPATHIC OSTEONECROSIS OF THE FEMORAL HEAD GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Colitis Ulcerative Ulcerative colitis Pubtator 27517910 Associate
★☆☆☆☆
Found in Text Mining only
Diabetes Mellitus Type 1 Diabetes mellitus, type 1 Pubtator 36175575 Stimulate
★☆☆☆☆
Found in Text Mining only
Hyperlipidemias Hyperlipidemia Pubtator 36175575 Associate
★☆☆☆☆
Found in Text Mining only
Hypothyroidism Hypothyroidism Pubtator 36175575 Associate
★☆☆☆☆
Found in Text Mining only
Nervous System Diseases Nervous system disease Pubtator 36175575 Associate
★☆☆☆☆
Found in Text Mining only
Polycystic Ovary Syndrome Polycystic ovary syndrome Pubtator 36175575 Associate
★☆☆☆☆
Found in Text Mining only
Ulcerative Colitis Ulcerative colitis BEFREE 27517910
★☆☆☆☆
Found in Text Mining only