Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	5768
Gene name	Quiescin sulfhydryl oxidase 1
Gene symbol	QSOX1
Synonyms (NCBI Gene)	Q6QSCN6
Chromosome	1
Chromosome location	1q25.2
Summary	This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene play

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miRTarBase ID	miRNA	Experiments	Reference
MIRT022900	hsa-miR-124-3p	Microarray	18668037
MIRT051544	hsa-let-7e-5p	CLASH	23622248
MIRT722484	hsa-miR-4301	HITS-CLIP	19536157
MIRT722483	hsa-miR-532-3p	HITS-CLIP	19536157
MIRT722482	hsa-miR-6859-3p	HITS-CLIP	19536157
MIRT722481	hsa-miR-711	HITS-CLIP	19536157
MIRT722480	hsa-miR-3156-3p	HITS-CLIP	19536157
MIRT722479	hsa-miR-1343-3p	HITS-CLIP	19536157
MIRT722478	hsa-miR-6783-3p	HITS-CLIP	19536157
MIRT521552	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT521551	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT521550	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT521549	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT521548	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT521547	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT521546	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT521545	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT521544	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT521543	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT521542	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT521541	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT521540	hsa-miR-302e	HITS-CLIP	23313552
MIRT521539	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT521538	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT521537	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT521536	hsa-miR-520b	HITS-CLIP	23313552
MIRT521535	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT521534	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT521533	hsa-miR-520e	HITS-CLIP	23313552
MIRT521532	hsa-miR-3159	HITS-CLIP	23313552
MIRT521531	hsa-miR-520g-3p	HITS-CLIP	23313552
MIRT521530	hsa-miR-520h	HITS-CLIP	23313552
MIRT521529	hsa-miR-186-3p	HITS-CLIP	23313552
MIRT521528	hsa-miR-1234-3p	HITS-CLIP	23313552
MIRT521527	hsa-miR-7107-5p	HITS-CLIP	23313552
MIRT521526	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT521525	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT521552	hsa-miR-106a-5p	PAR-CLIP	23446348
MIRT521551	hsa-miR-106b-5p	PAR-CLIP	23446348
MIRT521550	hsa-miR-17-5p	PAR-CLIP	23446348
MIRT521549	hsa-miR-20a-5p	PAR-CLIP	23446348
MIRT521548	hsa-miR-20b-5p	PAR-CLIP	23446348
MIRT521547	hsa-miR-519d-3p	PAR-CLIP	23446348
MIRT521546	hsa-miR-526b-3p	PAR-CLIP	23446348
MIRT521545	hsa-miR-93-5p	PAR-CLIP	23446348
MIRT521544	hsa-miR-302a-3p	PAR-CLIP	23446348
MIRT521543	hsa-miR-302b-3p	PAR-CLIP	23446348
MIRT521542	hsa-miR-302c-3p	PAR-CLIP	23446348
MIRT521541	hsa-miR-302d-3p	PAR-CLIP	23446348
MIRT521540	hsa-miR-302e	PAR-CLIP	23446348
MIRT521539	hsa-miR-372-3p	PAR-CLIP	23446348
MIRT521538	hsa-miR-373-3p	PAR-CLIP	23446348
MIRT521537	hsa-miR-520a-3p	PAR-CLIP	23446348
MIRT521536	hsa-miR-520b	PAR-CLIP	23446348
MIRT521535	hsa-miR-520c-3p	PAR-CLIP	23446348
MIRT521534	hsa-miR-520d-3p	PAR-CLIP	23446348
MIRT521533	hsa-miR-520e	PAR-CLIP	23446348
MIRT521532	hsa-miR-3159	PAR-CLIP	23446348
MIRT521531	hsa-miR-520g-3p	PAR-CLIP	23446348
MIRT521530	hsa-miR-520h	PAR-CLIP	23446348
MIRT521529	hsa-miR-186-3p	PAR-CLIP	23446348
MIRT521528	hsa-miR-1234-3p	PAR-CLIP	23446348
MIRT521527	hsa-miR-7107-5p	PAR-CLIP	23446348
MIRT521526	hsa-miR-150-5p	PAR-CLIP	23446348
MIRT521525	hsa-miR-6778-3p	PAR-CLIP	23446348
MIRT521524	hsa-miR-6807-5p	PAR-CLIP	23446348
MIRT521523	hsa-miR-320e	PAR-CLIP	23446348
MIRT521522	hsa-miR-4781-3p	PAR-CLIP	23446348
MIRT521521	hsa-miR-4716-5p	PAR-CLIP	23446348
MIRT521520	hsa-miR-1273f	PAR-CLIP	23446348
MIRT521519	hsa-miR-3926	PAR-CLIP	23446348
MIRT521518	hsa-miR-6835-5p	PAR-CLIP	23446348
MIRT521517	hsa-miR-6752-5p	PAR-CLIP	23446348
MIRT521516	hsa-miR-6842-5p	PAR-CLIP	23446348
MIRT521515	hsa-miR-7110-5p	PAR-CLIP	23446348
MIRT521514	hsa-miR-193b-5p	PAR-CLIP	23446348
MIRT521513	hsa-miR-6832-5p	PAR-CLIP	23446348
MIRT521512	hsa-miR-197-3p	PAR-CLIP	23446348
MIRT521511	hsa-miR-548s	PAR-CLIP	23446348
MIRT521510	hsa-miR-4701-5p	PAR-CLIP	23446348
MIRT521509	hsa-miR-588	PAR-CLIP	23446348
MIRT521508	hsa-miR-4435	PAR-CLIP	23446348
MIRT521507	hsa-miR-3187-3p	PAR-CLIP	23446348
MIRT521506	hsa-miR-6751-5p	PAR-CLIP	23446348
MIRT521505	hsa-miR-6803-5p	PAR-CLIP	23446348
MIRT521504	hsa-miR-5096	PAR-CLIP	23446348
MIRT722484	hsa-miR-4301	HITS-CLIP	19536157
MIRT722483	hsa-miR-532-3p	HITS-CLIP	19536157
MIRT722482	hsa-miR-6859-3p	HITS-CLIP	19536157
MIRT722481	hsa-miR-711	HITS-CLIP	19536157
MIRT722480	hsa-miR-3156-3p	HITS-CLIP	19536157
MIRT722479	hsa-miR-1343-3p	HITS-CLIP	19536157
MIRT722478	hsa-miR-6783-3p	HITS-CLIP	19536157
MIRT521552	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT521551	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT521550	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT521549	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT521548	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT521547	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT521546	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT521545	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT521544	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT521543	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT521542	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT521541	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT521540	hsa-miR-302e	HITS-CLIP	23313552
MIRT521539	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT521538	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT521537	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT521536	hsa-miR-520b	HITS-CLIP	23313552
MIRT521535	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT521534	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT521533	hsa-miR-520e	HITS-CLIP	23313552
MIRT521532	hsa-miR-3159	HITS-CLIP	23313552
MIRT521531	hsa-miR-520g-3p	HITS-CLIP	23313552
MIRT521530	hsa-miR-520h	HITS-CLIP	23313552
MIRT521529	hsa-miR-186-3p	HITS-CLIP	23313552
MIRT521528	hsa-miR-1234-3p	HITS-CLIP	23313552
MIRT521527	hsa-miR-7107-5p	HITS-CLIP	23313552
MIRT521526	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT521525	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT521552	hsa-miR-106a-5p	PAR-CLIP	23446348
MIRT521551	hsa-miR-106b-5p	PAR-CLIP	23446348
MIRT521550	hsa-miR-17-5p	PAR-CLIP	23446348
MIRT521549	hsa-miR-20a-5p	PAR-CLIP	23446348
MIRT521548	hsa-miR-20b-5p	PAR-CLIP	23446348
MIRT521547	hsa-miR-519d-3p	PAR-CLIP	23446348
MIRT521546	hsa-miR-526b-3p	PAR-CLIP	23446348
MIRT521545	hsa-miR-93-5p	PAR-CLIP	23446348
MIRT521544	hsa-miR-302a-3p	PAR-CLIP	23446348
MIRT521543	hsa-miR-302b-3p	PAR-CLIP	23446348
MIRT521542	hsa-miR-302c-3p	PAR-CLIP	23446348
MIRT521541	hsa-miR-302d-3p	PAR-CLIP	23446348
MIRT521540	hsa-miR-302e	PAR-CLIP	23446348
MIRT521539	hsa-miR-372-3p	PAR-CLIP	23446348
MIRT521538	hsa-miR-373-3p	PAR-CLIP	23446348
MIRT521537	hsa-miR-520a-3p	PAR-CLIP	23446348
MIRT521536	hsa-miR-520b	PAR-CLIP	23446348
MIRT521535	hsa-miR-520c-3p	PAR-CLIP	23446348
MIRT521534	hsa-miR-520d-3p	PAR-CLIP	23446348
MIRT521533	hsa-miR-520e	PAR-CLIP	23446348
MIRT521532	hsa-miR-3159	PAR-CLIP	23446348
MIRT521531	hsa-miR-520g-3p	PAR-CLIP	23446348
MIRT521530	hsa-miR-520h	PAR-CLIP	23446348
MIRT521529	hsa-miR-186-3p	PAR-CLIP	23446348
MIRT521528	hsa-miR-1234-3p	PAR-CLIP	23446348
MIRT521527	hsa-miR-7107-5p	PAR-CLIP	23446348
MIRT521526	hsa-miR-150-5p	PAR-CLIP	23446348
MIRT521525	hsa-miR-6778-3p	PAR-CLIP	23446348
MIRT521524	hsa-miR-6807-5p	PAR-CLIP	23446348
MIRT521523	hsa-miR-320e	PAR-CLIP	23446348
MIRT521522	hsa-miR-4781-3p	PAR-CLIP	23446348
MIRT521521	hsa-miR-4716-5p	PAR-CLIP	23446348
MIRT521520	hsa-miR-1273f	PAR-CLIP	23446348
MIRT521519	hsa-miR-3926	PAR-CLIP	23446348
MIRT521518	hsa-miR-6835-5p	PAR-CLIP	23446348
MIRT521517	hsa-miR-6752-5p	PAR-CLIP	23446348
MIRT521516	hsa-miR-6842-5p	PAR-CLIP	23446348
MIRT521515	hsa-miR-7110-5p	PAR-CLIP	23446348
MIRT521514	hsa-miR-193b-5p	PAR-CLIP	23446348
MIRT521513	hsa-miR-6832-5p	PAR-CLIP	23446348
MIRT521512	hsa-miR-197-3p	PAR-CLIP	23446348
MIRT521511	hsa-miR-548s	PAR-CLIP	23446348
MIRT521510	hsa-miR-4701-5p	PAR-CLIP	23446348
MIRT521509	hsa-miR-588	PAR-CLIP	23446348
MIRT521508	hsa-miR-4435	PAR-CLIP	23446348
MIRT521507	hsa-miR-3187-3p	PAR-CLIP	23446348
MIRT521506	hsa-miR-6751-5p	PAR-CLIP	23446348
MIRT521505	hsa-miR-6803-5p	PAR-CLIP	23446348
MIRT521504	hsa-miR-5096	PAR-CLIP	23446348
MIRT1280324	hsa-miR-1253	CLIP-seq
MIRT1280325	hsa-miR-185	CLIP-seq
MIRT1280326	hsa-miR-4306	CLIP-seq
MIRT1280327	hsa-miR-4644	CLIP-seq
MIRT1280328	hsa-miR-1200	CLIP-seq
MIRT1280329	hsa-miR-1260	CLIP-seq
MIRT1280330	hsa-miR-1260b	CLIP-seq
MIRT1280331	hsa-miR-188-3p	CLIP-seq
MIRT1280332	hsa-miR-3074-5p	CLIP-seq
MIRT1280333	hsa-miR-3140-5p	CLIP-seq
MIRT1280334	hsa-miR-3689a-3p	CLIP-seq
MIRT1280335	hsa-miR-3689c	CLIP-seq
MIRT1280336	hsa-miR-3936	CLIP-seq
MIRT1280337	hsa-miR-4651	CLIP-seq
MIRT1280338	hsa-miR-4680-3p	CLIP-seq
MIRT1280339	hsa-miR-4717-5p	CLIP-seq
MIRT1280340	hsa-miR-4728-5p	CLIP-seq
MIRT1280341	hsa-miR-608	CLIP-seq
MIRT1280342	hsa-miR-645	CLIP-seq
MIRT2082800	hsa-miR-1179	CLIP-seq
MIRT2082801	hsa-miR-4289	CLIP-seq
MIRT2308127	hsa-miR-124	CLIP-seq
MIRT2308128	hsa-miR-3130-3p	CLIP-seq
MIRT2308129	hsa-miR-3152-5p	CLIP-seq
MIRT2308130	hsa-miR-3192	CLIP-seq
MIRT2308131	hsa-miR-3622a-3p	CLIP-seq
MIRT2308132	hsa-miR-3622b-3p	CLIP-seq
MIRT2308133	hsa-miR-4786-5p	CLIP-seq
MIRT2308134	hsa-miR-4793-3p	CLIP-seq
MIRT2308135	hsa-miR-506	CLIP-seq
MIRT2308136	hsa-miR-544	CLIP-seq
MIRT2308137	hsa-miR-634	CLIP-seq
MIRT2308127	hsa-miR-124	CLIP-seq
MIRT2393309	hsa-miR-1913	CLIP-seq
MIRT2393310	hsa-miR-324-3p	CLIP-seq
MIRT2393311	hsa-miR-3714	CLIP-seq
MIRT2393312	hsa-miR-3910	CLIP-seq
MIRT2393313	hsa-miR-4313	CLIP-seq
MIRT2308135	hsa-miR-506	CLIP-seq
MIRT2308127	hsa-miR-124	CLIP-seq
MIRT2308135	hsa-miR-506	CLIP-seq
MIRT2457566	hsa-miR-28-5p	CLIP-seq
MIRT2457567	hsa-miR-3139	CLIP-seq
MIRT2457568	hsa-miR-3612	CLIP-seq
MIRT2457569	hsa-miR-4443	CLIP-seq
MIRT2457570	hsa-miR-4487	CLIP-seq
MIRT2457571	hsa-miR-650	CLIP-seq
MIRT2457572	hsa-miR-708	CLIP-seq
MIRT2082800	hsa-miR-1179	CLIP-seq
MIRT2605391	hsa-miR-1270	CLIP-seq
MIRT2605392	hsa-miR-24	CLIP-seq
MIRT2605393	hsa-miR-3155	CLIP-seq
MIRT2605394	hsa-miR-3155b	CLIP-seq
MIRT2605395	hsa-miR-4257	CLIP-seq
MIRT2605396	hsa-miR-432	CLIP-seq
MIRT2605397	hsa-miR-4419a	CLIP-seq
MIRT2605398	hsa-miR-4510	CLIP-seq
MIRT2605399	hsa-miR-4531	CLIP-seq
MIRT2308133	hsa-miR-4786-5p	CLIP-seq
MIRT2605400	hsa-miR-484	CLIP-seq
MIRT2605401	hsa-miR-620	CLIP-seq
MIRT2082800	hsa-miR-1179	CLIP-seq
MIRT2605391	hsa-miR-1270	CLIP-seq
MIRT2689198	hsa-miR-135a	CLIP-seq
MIRT2689199	hsa-miR-135b	CLIP-seq
MIRT2605392	hsa-miR-24	CLIP-seq
MIRT2308129	hsa-miR-3152-5p	CLIP-seq
MIRT2605393	hsa-miR-3155	CLIP-seq
MIRT2605394	hsa-miR-3155b	CLIP-seq
MIRT2308131	hsa-miR-3622a-3p	CLIP-seq
MIRT2308132	hsa-miR-3622b-3p	CLIP-seq
MIRT2689200	hsa-miR-3670	CLIP-seq
MIRT2605395	hsa-miR-4257	CLIP-seq
MIRT2605396	hsa-miR-432	CLIP-seq
MIRT2605397	hsa-miR-4419a	CLIP-seq
MIRT2689201	hsa-miR-4468	CLIP-seq
MIRT2605398	hsa-miR-4510	CLIP-seq
MIRT2605399	hsa-miR-4531	CLIP-seq
MIRT2308133	hsa-miR-4786-5p	CLIP-seq
MIRT2605400	hsa-miR-484	CLIP-seq
MIRT2605401	hsa-miR-620	CLIP-seq

Show/Hide all (28)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IBA
GO:0000139	Component	Golgi membrane	IDA	17331072, 29757379
GO:0000139	Component	Golgi membrane	IEA
GO:0003756	Function	Protein disulfide isomerase activity	IBA
GO:0003756	Function	Protein disulfide isomerase activity	IDA	17331072, 18393449
GO:0005576	Component	Extracellular region	IEA
GO:0005576	Component	Extracellular region	TAS
GO:0005615	Component	Extracellular space	HDA	16502470
GO:0005615	Component	Extracellular space	IBA
GO:0005615	Component	Extracellular space	IDA	10708601
GO:0005788	Component	Endoplasmic reticulum lumen	TAS
GO:0005794	Component	Golgi apparatus	IDA
GO:0005794	Component	Golgi apparatus	IEA
GO:0006457	Process	Protein folding	IBA
GO:0016020	Component	Membrane	IEA
GO:0016242	Process	Negative regulation of macroautophagy	IMP	24475161
GO:0016491	Function	Oxidoreductase activity	IEA
GO:0016971	Function	Flavin-dependent sulfhydryl oxidase activity	IBA
GO:0016971	Function	Flavin-dependent sulfhydryl oxidase activity	IDA	17331072, 18393449
GO:0016971	Function	Flavin-dependent sulfhydryl oxidase activity	IEA
GO:0016972	Function	Thiol oxidase activity	IEA
GO:0031093	Component	Platelet alpha granule lumen	TAS
GO:0035580	Component	Specific granule lumen	TAS
GO:0070062	Component	Extracellular exosome	HDA	23533145
GO:0070062	Component	Extracellular exosome	IDA	21082674
GO:0071949	Function	FAD binding	IDA	20211621
GO:0085029	Process	Extracellular matrix assembly	IMP	23867277
GO:1904724	Component	Tertiary granule lumen	TAS

MIM	HGNC	e!Ensembl
603120	9756	ENSG00000116260

O00391

Protein name

Sulfhydryl oxidase 1 (hQSOX) (EC 1.8.3.2) (Quiescin Q6)

Protein function

Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide (PubMed:17331072, PubMed:18393449, PubMed:23704371, PubMed:23867277, PubMed:30367560). Plays a role in dis

PDB

3LLI , 3LLK , 3Q6O , 4IJ3

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00085	Thioredoxin	42 → 147	Thioredoxin	Domain
PF18108	QSOX_Trx1	162 → 269	QSOX Trx-like domain	Domain
PF18371	FAD_SOX	295 → 396	Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase	Domain
PF04777	Evr1_Alr	405 → 504	Erv1 / Alr family	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in heart, placenta, lung, liver, skeletal muscle, pancreas and very weakly in brain and kidney. {ECO:0000269|PubMed:10708601, ECO:0000269|Ref.8}.

Sequence

MRRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSA
WAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPT
VRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFF
ARNNEEYLALIFEKGGSYLGREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLL
FRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIAPTVWKLADRSKIY
MADLESALHYILRIEVGRFPVLEGQRLVALKKFVAVLAKYFPGRPLVQNFLHSVNEWLKR
QKRNKIPYSFFKTALDDRKEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAAR
QNVDHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWSS
HNRVNARLAGAPSEDPQFPKVQWPPRELCSACHNERLDVPVWDVEATLNFLKAHFSPSNI
ILDFPAAGSAARRDVQNVAAAPELAMGALELESRNSTLDPGKPEMMKSPTNTTPHVPAEG
PEASRPPKLHPGLRAAPGQEPPEHMAELQRNEQEQPLGQWHLSKRDTGAALLAESRAEKN
RLWGPLEVRRVGRSSKQLVDIPEGQLEARAGRGRGQWLQVLGGGFSYLDISLCVGLYSLS
FMGLLAMYTYFQAKIRALKGHAGHPAA

Sequence length

747

Interactions

View interactions

	Reactome
			Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Neutrophil degranulation Post-translational protein phosphorylation

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ANOREXIA NERVOSA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
EATING DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (22)

Disease Name	Disease (Merged)	Source	PMID	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adenocarcinoma	Adenocarcinoma	BEFREE	29757379	★★★★★ ★☆☆☆☆ Found in Text Mining only
Adenocarcinoma of pancreas	Pancreatic adenocarcinoma	BEFREE	23098186	★★★★★ ★☆☆☆☆ Found in Text Mining only
ANOPHTHALMIA AND PULMONARY HYPOPLASIA	Syndromic microphthalmia	BEFREE	26976451	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	23098186, 23460839, 23536962, 23680167, 24359107, 24475161	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	30336636	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ductal Carcinoma	Ductal Carcinoma	BEFREE	23098186	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	28977922	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver Cirrhosis	Liver Cirrhosis	BEFREE	28977922	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	23098186, 23460839, 23536962, 23680167, 24359107, 24475161	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	30336636	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	24008827	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	23098186, 24359107, 29804717	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	23680167, 24359107, 30336636, 30910009	★★★★★ ★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	BEFREE	23098186, 23536962	★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasopharyngeal carcinoma	Nasopharyngeal Carcinoma	BEFREE	29423042	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	23098186, 23536962, 24359107, 24475161, 26158899, 29804717, 31575656	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	24008827	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Ductal Adenocarcinoma	Pancreatic adenocarcinoma	BEFREE	21989104	★★★★★ ★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	BEFREE	29686831	★★★★★ ★☆☆☆☆ Found in Text Mining only
Patent ductus arteriosus	Patent ductus arteriosus	BEFREE	21989104	★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	29804717	★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Intraepithelial Neoplasias	Prostatic Neoplasms	BEFREE	19597465	★★★★★ ★☆☆☆☆ Found in Text Mining only

QSOX1 (quiescin sulfhydryl oxidase 1)