Gene Gene information from NCBI Gene database.
Entrez ID 57532
Gene name Nuclear FMR1 interacting protein 2
Gene symbol NUFIP2
Synonyms (NCBI Gene)
182-FIP82-FIPFIP-82NUFP2PIG1
Chromosome 17
Chromosome location 17q11.2
miRNA miRNA information provided by mirtarbase database.
3245
miRTarBase ID miRNA Experiments Reference
MIRT005142 hsa-miR-30a-5p pSILAC 18668040
MIRT016195 hsa-miR-590-3p Sequencing 20371350
MIRT019613 hsa-miR-340-5p Sequencing 20371350
MIRT021149 hsa-miR-186-5p Sequencing 20371350
MIRT021672 hsa-miR-140-3p Sequencing 20371350
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
18
GO ID Ontology Definition Evidence Reference
GO:0003723 Function RNA binding HDA 22658674, 22681889
GO:0003723 Function RNA binding IBA
GO:0003723 Function RNA binding IDA 12837692
GO:0003723 Function RNA binding IEA
GO:0005515 Function Protein binding IPI 12837692, 16407062, 21653829, 25416956, 26184334, 28514442, 32296183, 32525608, 32814053, 33961781, 35709258
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
609356 17634 ENSG00000108256
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q7Z417
Protein name FMR1-interacting protein NUFIP2 (82 kDa FMRP-interacting protein) (82-FIP) (Cell proliferation-inducing gene 1 protein) (FMRP-interacting protein 2) (Nuclear FMR1-interacting protein 2)
Protein function Binds RNA.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15293 NUFIP2 89 688 Nuclear fragile X mental retardation-interacting protein 2 Family
Sequence
Sequence length 695
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
9
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ATTENTION DEFICIT HYPERACTIVITY DISORDER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
BREAST CARCINOMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
GOUT GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
MIGRAINE DISORDER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Alzheimer Disease Alzheimer disease Pubtator 37440991 Associate
★☆☆☆☆
Found in Text Mining only
Arthritis Rheumatoid Rheumatoid arthritis Pubtator 33482886 Associate
★☆☆☆☆
Found in Text Mining only
Asthma Asthma BEFREE 15879417
★☆☆☆☆
Found in Text Mining only
Astrocytoma Astrocytoma BEFREE 27683117
★☆☆☆☆
Found in Text Mining only
ATRIAL SEPTAL DEFECT 1 Atrial Septal Defect BEFREE 17050285
★☆☆☆☆
Found in Text Mining only
Atrial Septal Defects Atrial Septal Defect BEFREE 17050285
★☆☆☆☆
Found in Text Mining only
Attention Deficit Disorder Attention Deficit Hyperactivity Disorder BEFREE 18787232
★☆☆☆☆
Found in Text Mining only
Attention Deficit Disorder with Hyperactivity Attention deficit hyperactivity disorder Pubtator 32460900 Associate
★☆☆☆☆
Found in Text Mining only
Attention deficit hyperactivity disorder Attention Deficit Hyperactivity Disorder BEFREE 18787232
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Autism Spectrum Disorder Autism Pubtator 24267887, 27260404, 28344757, 32243819 Associate
★☆☆☆☆
Found in Text Mining only