Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	57507
Gene name	Zinc finger protein 608
Gene symbol	ZNF608
Synonyms (NCBI Gene)	NY-REN-36
Chromosome	5
Chromosome location	5q23.2

119

Show/Hide all (119)

miRTarBase ID	miRNA	Experiments	Reference
MIRT021566	hsa-miR-142-3p	Microarray	17612493
MIRT043368	hsa-miR-331-3p	CLASH	23622248
MIRT508448	hsa-miR-5683	HITS-CLIP	21572407
MIRT508446	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT508443	hsa-let-7f-2-3p	HITS-CLIP	21572407
MIRT508442	hsa-miR-1185-1-3p	HITS-CLIP	21572407
MIRT508441	hsa-miR-1185-2-3p	HITS-CLIP	21572407
MIRT508440	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT508439	hsa-miR-3924	HITS-CLIP	21572407
MIRT508438	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT614662	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT614661	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT614660	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT614659	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT614658	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT614657	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT614656	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT614655	hsa-miR-5582-3p	HITS-CLIP	23824327
MIRT545815	hsa-miR-548u	PAR-CLIP	20371350
MIRT545814	hsa-miR-7161-5p	PAR-CLIP	20371350
MIRT545813	hsa-miR-1183	PAR-CLIP	20371350
MIRT545811	hsa-miR-4272	PAR-CLIP	20371350
MIRT311394	hsa-miR-4668-5p	PAR-CLIP	20371350
MIRT508448	hsa-miR-5683	PAR-CLIP	21572407
MIRT552369	hsa-miR-3163	PAR-CLIP	21572407
MIRT508447	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT508446	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT508445	hsa-miR-190a-5p	PAR-CLIP	21572407
MIRT508444	hsa-miR-190b	PAR-CLIP	21572407
MIRT508443	hsa-let-7f-2-3p	PAR-CLIP	21572407
MIRT508442	hsa-miR-1185-1-3p	PAR-CLIP	21572407
MIRT508441	hsa-miR-1185-2-3p	PAR-CLIP	21572407
MIRT508440	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT508439	hsa-miR-3924	PAR-CLIP	21572407
MIRT552368	hsa-miR-6083	PAR-CLIP	21572407
MIRT508438	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT545815	hsa-miR-548u	PAR-CLIP	21572407
MIRT545814	hsa-miR-7161-5p	PAR-CLIP	21572407
MIRT545813	hsa-miR-1183	PAR-CLIP	21572407
MIRT545811	hsa-miR-4272	PAR-CLIP	21572407
MIRT545812	hsa-miR-5697	PAR-CLIP	21572407
MIRT545810	hsa-miR-1297	PAR-CLIP	21572407
MIRT545809	hsa-miR-26a-5p	PAR-CLIP	21572407
MIRT545808	hsa-miR-26b-5p	PAR-CLIP	21572407
MIRT545807	hsa-miR-4465	PAR-CLIP	21572407
MIRT311394	hsa-miR-4668-5p	PAR-CLIP	21572407
MIRT508448	hsa-miR-5683	PAR-CLIP	23446348
MIRT508447	hsa-miR-410-3p	PAR-CLIP	23446348
MIRT508446	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT508445	hsa-miR-190a-5p	PAR-CLIP	23446348
MIRT508444	hsa-miR-190b	PAR-CLIP	23446348
MIRT508443	hsa-let-7f-2-3p	PAR-CLIP	23446348
MIRT508442	hsa-miR-1185-1-3p	PAR-CLIP	23446348
MIRT508441	hsa-miR-1185-2-3p	PAR-CLIP	23446348
MIRT508440	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT508439	hsa-miR-3924	PAR-CLIP	23446348
MIRT508438	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT439193	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT439193	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT508448	hsa-miR-5683	HITS-CLIP	21572407
MIRT508446	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT508443	hsa-let-7f-2-3p	HITS-CLIP	21572407
MIRT508442	hsa-miR-1185-1-3p	HITS-CLIP	21572407
MIRT508441	hsa-miR-1185-2-3p	HITS-CLIP	21572407
MIRT508440	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT508439	hsa-miR-3924	HITS-CLIP	21572407
MIRT508438	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT614662	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT614661	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT614660	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT614659	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT614658	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT614657	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT614656	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT614655	hsa-miR-5582-3p	HITS-CLIP	23824327
MIRT545815	hsa-miR-548u	PAR-CLIP	20371350
MIRT545814	hsa-miR-7161-5p	PAR-CLIP	20371350
MIRT545813	hsa-miR-1183	PAR-CLIP	20371350
MIRT545811	hsa-miR-4272	PAR-CLIP	20371350
MIRT311394	hsa-miR-4668-5p	PAR-CLIP	20371350
MIRT508448	hsa-miR-5683	PAR-CLIP	21572407
MIRT552369	hsa-miR-3163	PAR-CLIP	21572407
MIRT508447	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT508446	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT508445	hsa-miR-190a-5p	PAR-CLIP	21572407
MIRT508444	hsa-miR-190b	PAR-CLIP	21572407
MIRT508443	hsa-let-7f-2-3p	PAR-CLIP	21572407
MIRT508442	hsa-miR-1185-1-3p	PAR-CLIP	21572407
MIRT508441	hsa-miR-1185-2-3p	PAR-CLIP	21572407
MIRT508440	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT508439	hsa-miR-3924	PAR-CLIP	21572407
MIRT552368	hsa-miR-6083	PAR-CLIP	21572407
MIRT508438	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT545815	hsa-miR-548u	PAR-CLIP	21572407
MIRT545814	hsa-miR-7161-5p	PAR-CLIP	21572407
MIRT545813	hsa-miR-1183	PAR-CLIP	21572407
MIRT545811	hsa-miR-4272	PAR-CLIP	21572407
MIRT545812	hsa-miR-5697	PAR-CLIP	21572407
MIRT545810	hsa-miR-1297	PAR-CLIP	21572407
MIRT545809	hsa-miR-26a-5p	PAR-CLIP	21572407
MIRT545808	hsa-miR-26b-5p	PAR-CLIP	21572407
MIRT545807	hsa-miR-4465	PAR-CLIP	21572407
MIRT311394	hsa-miR-4668-5p	PAR-CLIP	21572407
MIRT508448	hsa-miR-5683	PAR-CLIP	23446348
MIRT508447	hsa-miR-410-3p	PAR-CLIP	23446348
MIRT508446	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT508445	hsa-miR-190a-5p	PAR-CLIP	23446348
MIRT508444	hsa-miR-190b	PAR-CLIP	23446348
MIRT508443	hsa-let-7f-2-3p	PAR-CLIP	23446348
MIRT508442	hsa-miR-1185-1-3p	PAR-CLIP	23446348
MIRT508441	hsa-miR-1185-2-3p	PAR-CLIP	23446348
MIRT508440	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT508439	hsa-miR-3924	PAR-CLIP	23446348
MIRT508438	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT2379944	hsa-miR-4528	CLIP-seq
MIRT2397638	hsa-miR-27a	CLIP-seq
MIRT2397639	hsa-miR-27b	CLIP-seq
MIRT2379944	hsa-miR-4528	CLIP-seq
MIRT2397640	hsa-miR-513a-5p	CLIP-seq

Show/Hide all (6)

GO ID	Ontology	Definition	Evidence
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IEA
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	ISS
GO:0005634	Component	Nucleus	IBA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
620972	29238	ENSG00000168916

Q9ULD9

Protein name

Zinc finger protein 608 (Renal carcinoma antigen NY-REN-36)

Protein function

Transcription factor, which represses ZNF609 transcription.

Family and domains

Sequence

MSVNISTAGKGVDPNTVDTYDSGDDWEIGVGNLIIDLDADLEKDRQKFEMNNSTTTTSSS
NSKDCGGPASSGAGATAALADGLKFASVQASAPQGNSHKETSKSKVKRSKTSKDANKSLP
SAALYGIPEISSTGKRQEVQGRPGEATGMNSALGQSVSSGGSGNPNSNSTSTSTSAATAG
AGSCGKSKEEKPGKSQSSRGAKRDKDAGKSRKDKHDLLQGHQNGSGSQAPSGGHLYGFGA
KSNGGGASPFHCGGTGSGSVAAAGEVSKSAPDSGLMGNSMLVKKEEEEEESHRRIKKLKT
EKVDPLFTVPAPPPPISSSLTPQILPSYFSPSSSNIAAPVEQLLVRTRSVGVNTCEVGVV
TEPECLGPCEPGTSVNLEGIVWHETEEGVLVVNVTWRNKTYVGTLLDCTKHDWAPPRFCE
SPTSDLEMRGGRGRGKRARSAAAAPGSEASFTESRGLQNKNRGGANGKGRRGSLNASGRR
TPPNCAAEDIKASPSSTNKRKNKPPMELDLNSSSEDNKPGKRVRTNSRSTPTTPQGKPET
TFLDQGCSSPVLIDCPHPNCNKKYKHINGLRYHQAHAHLDPENKLEFEPDSEDKISDCEE
GLSNVALECSEPSTSVSAYDQLKAPASPGAGNPPGTPKGKRELMSNGPGSIIGAKAGKNS
GKKKGLNNELNNLPVISNMTAALDSCSAADGSLAAEMPKLEAEGLIDKKNLGDKEKGKKA
TNCKTDKNLSKLKSARPIAPAPAPTPPQLIAIPTATFTTTTTGTIPGLPSLTTTVVQATP
KSPPLKPIQPKPTIMGEPITVNPALVSLKDKKKKEKRKLKDKEGKETGSPKMDAKLGKLE
DSKGASKDLPGHFLKDHLNKNEGLANGLSESQESRMASIKAEADKVYTFTDNAPSPSIGS
ASRLECSTLVNGQAPMAPLHVLTQNGAESSAAKTSSPAYSDISDAADDGGSDSRSEGMRS
KASSPSDIISSKDSVVKGHSSTTAQSSQLKESHSPYYHSYDPYYSPSYMHPGQVGAPAAG
NSGSTQGMKIKKESEEDAEKKDKAEQLDSKKVDHNSASLQPQHQSVITQRHPALAQSLYY
GQYAYGLYMDQKSLMATSPAYRQQYEKYYEDQRLAEQKMAQTGRGDCERKSELPLKELGK
EETKQKNMPSATISKAPSTPEPNKNHSKLGPSVPNKTEETGKSQLLSNHQQQLQADSFKA
KQMENHQLIKEAVEMKSVMDSMKQTGVDPTSRFKQDPDSRTWHHYVYQPKYLDQQKSEEL
DREKKLKEDSPRKTPNKESGVPSLPVSLTSIKEEPKEAKHPDSQSMEESKLKNDDRKTPV
NWKDSRGTRVAVSSPMSQHQSYIQYLHAYPYPQMYDPSHPAYRAVSPVLMHSYPGAYLSP
GFHYPVYGKMSGREETEKVNTSPSVNTKTTTESKALDLLQQHANQYRSKSPAPVEKATAE
REREAERERDRHSPFGQRHLHTHHHTHVGMGYPLIPGQYDPFQGLTSAALVASQQVAAQA
SASGMFPGQRRE

Sequence length

1512

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (8)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ALZHEIMER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEMENTIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OBESITY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PANCREATIC CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PARKINSON DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCOLIOSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (9)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Asthma	Asthma	Pubtator	37466093	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Endometrial Neoplasms	Endometrial neoplasm	Pubtator	35876160	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	BEFREE	28064239		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	Pubtator	28064239	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphoma Follicular	Lymphoma	Pubtator	28064239	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	Pubtator	23347264	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Obesity	Obesity	BEFREE	24788522		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Pancreatic carcinoma	Pancreatic carcinoma	GWASCAT_DG	28470677		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Pulmonary Disease Chronic Obstructive	Chronic obstructive pulmonary disease	Pubtator	37466093	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

ZNF608 (zinc finger protein 608)