Gene Gene information from NCBI Gene database.
Entrez ID 57404
Gene name Cytochrome P450 family 20 subfamily A member 1
Gene symbol CYP20A1
Synonyms (NCBI Gene)
CYP-M
Chromosome 2
Chromosome location 2q33.2
Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein lacks
miRNA miRNA information provided by mirtarbase database.
1857
miRTarBase ID miRNA Experiments Reference
MIRT019761 hsa-miR-375 Microarray 20215506
MIRT023648 hsa-miR-1-3p Microarray 18668037
MIRT030397 hsa-miR-24-3p Microarray 19748357
MIRT717878 hsa-miR-1266-3p HITS-CLIP 19536157
MIRT717877 hsa-miR-3653-5p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
9
GO ID Ontology Definition Evidence Reference
GO:0004497 Function Monooxygenase activity IEA
GO:0005506 Function Iron ion binding IEA
GO:0005515 Function Protein binding IPI 28514442, 33961781
GO:0016020 Component Membrane HDA 19946888
GO:0016020 Component Membrane IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q6UW02
Protein name Cytochrome P450 20A1 (EC 1.14.-.-)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00067 p450 42 457 Cytochrome P450 Domain
Sequence
Sequence length 462
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
5
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ATTENTION DEFICIT HYPERACTIVITY DISORDER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
INSOMNIA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
MYOCARDIAL INFARCTION GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Carcinoma of lung Lung carcinoma BEFREE 31264381
★☆☆☆☆
Found in Text Mining only
Crohn Disease Crohn disease Pubtator 35872023 Associate
★☆☆☆☆
Found in Text Mining only
Hepatitis Chronic Hepatitis Pubtator 8390333 Associate
★☆☆☆☆
Found in Text Mining only
Lung Neoplasms Lung neoplasms Pubtator 31264381 Associate
★☆☆☆☆
Found in Text Mining only
Malignant neoplasm of lung Lung Cancer BEFREE 31264381
★☆☆☆☆
Found in Text Mining only
Pancreatic Neoplasms Pancreatic neoplasm Pubtator 28098172 Associate
★☆☆☆☆
Found in Text Mining only
Parkinson Disease Parkinson disease BEFREE 8797539
★☆☆☆☆
Found in Text Mining only
Parkinson Disease Parkinson disease Pubtator 9189044 Associate
★☆☆☆☆
Found in Text Mining only
PARKINSON DISEASE, LATE-ONSET Parkinson disease BEFREE 8797539
★☆☆☆☆
Found in Text Mining only
Polycystic Ovary Syndrome Polycystic ovary syndrome Pubtator 34233642 Stimulate
★☆☆☆☆
Found in Text Mining only